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| 1 | Mapping wetland changes in China between 1978 and 2008显示文摘Four wetland maps for all China have been produced,based on Landsat and CBERS-02B remote sensing data between 1978 and 2008 (1978,1990,2000 and 2008).These maps were mainly developed by manual interpretation and validated by substantial field investigation in 2009.Based on these maps,we analyzed the 2008 wetland distribution in China and discussed wetland changes and their drivers over the past 30 years.(i) There were about 324097 km 2 of wetlands in 2008,for which inland marshes or swamps were the most common wetland type (35%),with lakes (26%) second.Most of the wetlands were in Heilongjiang,Inner Mongolia,Qinghai and Tibet,occupying about 55% of the national wetland area.(ii) From 1978 to 2008,China's wetland area continually and significantly decreased,by about 33% based on changes in the wetland map.This was in sharp contrast to the increase in artificial wetlands,which increased by about 122%.Inland marshes accounted for the main loss of total wetlands from 1978 to 2000.From 2000 through 2008,riverine and lacustrine wetlands constituted the main wetland loss.Fortunately however,the rate of wetland loss decreased from 5523 to 831 km 2 /a.(iii) The change ratio of lost natural wetlands (including inland and coastal wetlands) to non-wetlands has decreased slightly over the past 30 years.From 1978 to 1990,nearly all natural wetlands (98%) lost were transformed into non-wetlands.However,the ratio declined to 86% from 1990 to 2000,and to 77% from 2000 to 2008.(iv) All Chinese provinces were divided into three groups according to patterns of wetland changes,which could relate to the driving forces of such changes.Tibet was completely different from other provinces,as it was one representative example in which there was a net wetland increase,because of global warming and decreased human activity since 1990.Increased economic development caused considerable wetland loss in most eastern provinces,and artificial wetlands increased. | NIU ZhenGuo ZHANG HaiYing WANG XianWei YAO WenBo ZHOU DeMin ZHAO KuiYi ZHAO Hui LI NaNa HUANG HuaBing LI CongCong YANG Jun LIU CaiXia LIU Shuang WANG Lin LI Zhan YANG ZhenZhong QIAO Fei ZHENG YaoMin CHEN YanLei SHENG YongWei GAO XiaoHong ZHU WeiHong WANG WenQing WANG Hong WENG YongLing ZHUANG DaFang LIU JiYuan LUO ZhiCai CHENG Xiao GUO ZiQi GONG Peng | 2012 | Chinese Science Bulletin2012，57，22： | 51 |
| 2 | Deep Learning Based 2D Human Pose Estimation:A Survey显示文摘Human pose estimation has received significant attention recently due to its various applications in the real world. As the performance of the state-of-the-art human pose estimation methods can be improved by deep learning, this paper presents a comprehensive survey of deep learning based human pose estimation methods and analyzes the methodologies employed. We summarize and discuss recent works with a methodologybased taxonomy. Single-person and multi-person pipelines are first reviewed separately. Then, the deep learning techniques applied in these pipelines are compared and analyzed. The datasets and metrics used in this task are also discussed and compared. The aim of this survey is to make every step in the estimation pipelines interpretable and to provide readers a readily comprehensible explanation. Moreover, the unsolved problems and challenges for future research are discussed. | Qi Dang Jianqin Yin Bin Wang Wenqing Zheng | 2019 | Tsinghua Science and Technology2019，24，6： | 14 |
| 3 | A human circulating immune cell landscape in aging and COVID-19显示文摘Age-associated changes in immune cells have been linked to an increased risk for infection.However,a global and detailed characterization of the changes that human circulating immune cells undergo with age is lacking.Here,we combined scRNA-seq,mass cytometry and sCATAC-seq to compare immune cell types in peripheral blood collected from young and old subjects and patients with COVID-19.We found that the immune cell landscape was reprogrammed with age and was characterized by T cell polarization from naive and memory cells to effector,cytotoxic,exhausted and reg-ulatory cells,along with increased late natural killer cells,age-associated B cells,inflammatory monocytes and age-associated dendritic cells.In addition,the expression of genes,which were implicated in coron-avirus susceptibility,was upregulated in a cell subtype-specific manner with age.Notably,COVID-19 promoted age-induced immune cell polarization and gene expression related to inflammation and cellular senes-cence.Therefore,these findings suggest that a dysreg-ulated immune system and increased gene expression associated with SARS-CoV-2 susceptibility may at least partially account for COVID-19 vulnerability in the elderly. | Yingfeng Zheng Xiuxing Liu Wenqing Le Lihui Xie He Li Wen Wen Si Wang Shuai Ma Zhaohao Huang Jinguo Ye Wen Shi Yanxia Ye Zunpeng Liu Moshi Song Weiqi Zhang Jing-Dong J.Han Juan Carlos lzpisua Belmonte Chuanle Xiao Jing Qu Hongyang Wang Guang-Hui Liu Wenru Su | 2020 | Protein & Cell2020，11，10： | 10 |
| 4 | Adsorption-energy-based activity descriptors for electrocatalysts in energy storage applications显示文摘Energy storage technologies, such as fuel cells, ammonia production and lithium–air batteries, are important strategies for addressing the global challenge of energy crisis and environmental pollution.Taking overpotential as a direct criterion, we illustrate in theory and experiment that the adsorption energies of charged species such as Li^++e^-and H^++e^-are a central parameter to describe catalytic activities related to electricity-in/electricity-out efficiencies. The essence of catalytic activity is revealed to relate with electronic coupling between catalysts and charged species. Based on adsorption energy, some activity descriptors such as d-band center, e_g-electron number and charge-transfer capacity are further defined by electronic properties of catalysts that directly affect interaction between catalysts and charged species. The present review is helpful for understanding the catalytic mechanisms of these electrocatalytic reactions and developing accurate catalytic descriptors, which can be employed to screen high-activity catalysts in future high-throughput calculations and experiments. | Youwei Wang Wujie Qiu Erhong Song Feng Gu Zhihui Zheng Xiaolin Zhao Yingqin Zhao Jianjun Liu Wenqing Zhang | 2018 | National Science Review2018，5，3： | 8 |
| 5 | An Epidemic of Hepatitis A--Liaoning Province,2020显示文摘What is already known about this topic?Hepatitis A(HA)is caused by acute hepatitis A virus(HAV)infection and was once very common in China.Following the 2008 introduction of the HA vaccine into the national Expanded Program on Immunization(EPI),the incidence of reported HA in China decreased markedly.However,HA epidemics still occur in Liaoning Province every 3–5 years,although with far fewer cases than in the pre-HA-vaccination era.What is added by this report?Between January 1,2020 and March 18,2020,the number of reported cases of HA in Dalian and Dandong cities of Liaoning Province increased significantly compared with the same period in previous years.All cases were sporadic,and cases were seen in nearly every township.The increase in HA occurred one month after local fresh seafood became available with most cases being among adults.A casecontrol study showed that consuming raw or undercooked seafood,clams,snapping shrimp,and oysters were significantly associated with the increase in HA.What are the implications for public health practices?Strengthening health education for residents to avoid consumption of raw seafood and encouraging HAV vaccination of adults aged 20 to 54 years are important to prevent periodic HAV endemic outbreaks.Further multisectoral cooperation must be emphasized on HA surveillance in areas with a high prevalence of HA. | Jing Sun Yuanqiu Li Xing Fang Yan Wang Yinan Han Yang Liu Jingyuan Cao Wenting Zhou Hui Zheng Wenqing Yao | 2020 | China CDC weekly2020，2，30： | 7 |
| 6 | 16S rRNA is a better choice than COI for DNA barcoding hydrozoans in the coastal waters of China显示文摘Identification of hydrozoan species is challenging, even for taxonomic experts, due to the scarcity of distinct morphological characters and phenotypic plasticity. DNA barcoding provides an efficient method for species identification, however, the choice between mitochondrial cytochrome c oxidase subunit I(COI) and large subunit ribosomal RNA gene(16S) as a standard barcode for hydrozoans is subject to debate. Herein, we directly compared the barcode potential of COI and 16S in hydrozoans using 339 sequences from 47 pelagic hydrozoan species. Analysis of Kimura 2-parameter genetic distances(K2P) documented the mean intraspecific/interspecific variation for COI and 16S to be 0.004/0.204 and 0.003/0.223, respectively. An obvious 'barcoding gap' was detected for all species in both markers and all individuals of a species clustered together in both the COI and 16S trees. These results suggested that the species within the studied taxa can be efficiently and accurately identified by COI and 16S. Furthermore, our results confirmed that 16S was a better phylogenetic marker for hydrozoans at the genus level, and in some cases at the family level. Considering the resolution and effectiveness for barcoding and phylogenetic analyses of Hydrozoa, we strongly recommend 16S as the standard barcode for hydrozoans. | ZHENG Lianming HE Jinru LIN Yuanshao CAO Wenqing ZHANG Wenjing | 2014 | Acta Oceanologica Sinica2014，33，4： | 7 |
| 7 | Composition and ecological distribution of ichthyoplankton in eastern Beibu Gulf显示文摘Surveys were conducted in four seasons in the eastern Beibu Gulf from July 2006 to November 2007,to determine the ichthyoplankton composition,abundance,as well as environmental factors impacted on their spatiotemporal distributions.The fish eggs and larvae were sorted from 303 zooplankton quantitative samples,in which at least 1 order,60 families,31 genera and 61 species of fish eggs and larvae were identified.The species number was highest in summer whereas lowest in winter.With the most abundant fish egg (the average density was 2.41 ind./m 3),spring was the main spawning season,while the greatest mean density of fish larva was 1.35 ind./m 3 in summer.In the whole year around,fish eggs had the trends to aggregate in the nearshore of Guangxi coast,fish larvae were more abundant in the northern water.Relationships between fish eggs and larvae abundance and environmental factors were analyzed by using the Yield-Density model.The spatiotemporal distribution of ichthyoplankton in eastern Beibu Gulf was closely related to the Chl a concentration,and the optimal temperature,salinity and Chl a were 19.4-21.7 C,31.8-33.1 and 1.5-4.8 mg/m 3,respectively.Additionally,the distribution of fish larvae could be effected by ocean currents in summer and autumn. | ZHOU Meiyu LIN Yuanshao YANG Shengyun CAO Wenqing ZHENG Lianming | 2011 | Acta Oceanologica Sinica2011，30，1： | 3 |
| 8 | Modes of genetic adaptations underlying functional innovations in the rumen显示文摘The rumen is the hallmark organ of ruminants and hosts a diverse ecosystem of microorganisms that facilitates efficient digestion of plant fibers.We analyzed 897 transcriptomes from three Cetartiodactyla lineages:ruminants,camels and cetaceans,as well as data from ruminant comparative genomics and functional assays to explore the genetic basis of rumen functional innovations.We identified genes with relatively high expression in the rumen,of which many appeared to be recruited from other tissues.These genes show functional enrichment in ketone body metabolism,regulation of microbial community,and epithelium absorption,which are the most prominent biological processes involved in rumen innovations.Several modes of genetic change underlying rumen functional innovations were uncovered,including coding mutations,genes newly evolved,and changes of regulatory elements.We validated that the key ketogenesis rate-limiting gene(HMGCS2)with five ruminant-specific mutations was under positive selection and exhibits higher synthesis activity than those of other mammals.Two newly evolved genes(LYZ1 and DEFB1)are resistant to Gram-positive bacteria and thereby may regulate microbial community equilibrium.Furthermore,we confirmed that the changes of regulatory elements accounted for the majority of rumen gene recruitment.These results greatly improve our understanding of rumen evolution and organ evo-devo in general. | Xiangyu Pan Yudong Cai Zongjun Li Xianqing Chen Rasmus Heller Nini Wang Yu Wang Chen Zhao Yong Wang Han Xu Songhai Li Ming Li Cunyuan Li Shengwei Hu Hui Li Kun Wang Lei Chen Bin Wei Zhuqing Zheng Weiwei Fu Yue Yang Tingting Zhang Zhuoting Hou Yueyang Yan Xiaoyang Lv Wei Sun Xinyu Li Shisheng Huang Lixiang Liu Shengyong Mao Wenqing Liu Jinlian Hua Zhipeng Li Guojie Zhang Yulin Chen Xihong Wang Qiang Qiu Brian PDalrymple Wen Wang Yu Jiang | 2021 | Science China(Life Sciences)2021，64，1： | 3 |
| 9 | PM_(2.5)and water-soluble inorganic ion concentrations decreased faster in urban than rural areas in China显示文摘We investigated variations of PM_(2.5)and water-soluble inorganic ions chemical characteristics at nine urban and rural sites in China using ground-based observations.From 2015 to 2019,mean PM_(2.5)concentration across all sites decreased by 41.9μg/m~3with a decline of 46%at urban sites and 28%at rural sites,where secondary inorganic aerosol(SIAs)contributed to 21%(urban sites)and 17%(rural sites)of the decreased PM_(2.5).SIAs concentrations underwent a decline at urban locations,while sulfate(SO_(4)^(2–)),nitrate(NO_(3)^(–)),and ammonium(NH_(4)^(+))decreased by 49.5%,31.3%and 31.6%,respectively.However,only SO_(4)^(2–)decreased at rural sites,NO_(3)^(–)increased by 21%and NH_(4)^(+)decreased slightly.Those changes contributed to an overall SIAs increase in 2019.Higher molar ratios of NO_(3)^(–)to SO_(4)^(2–)and NH_(4)^(+)to SO_(4)^(2–)were observed at urban sites than rural sites,being highest in the heavily polluted days.Mean molar ratios of NH_(3)/NH_xwere higher in 2019 than 2015 at both urban and rural sites,implying increasing NH_xremained as free NH_(3).Our observations indicated a slower transition from sulfate-driven to nitrate-driven aerosol pollution and less efficient control of NO_(x)than SO_(2)related aerosol formation in rural regions than urban regions.Moreover,the common factor at urban and rural sites appears to be a combination of lower SO_(4)^(2–)levels and an increasing fraction of NO_(3)^(–)to PM_(2.5)under NH_(4)^(+)-rich conditions.Our findings imply that synchronous reduction in NO_(x)and NH_(3)emissions especially rural areas would be effective to mitigate NO_(3)^(–)-driven aerosol pollution. | Yangyang Zhang Aohan Tang Chen Wang Xin Ma Yunzhe Li Wen Xu Xiaoping Xia Aihua Zheng Wenqing Li Zengguo Fang Xiufen Zhao Xianlong Peng Yuping Zhang Jian Han Lijuan Zhang Jeffrey L.Collett Jr Xuejun Liu | 2022 | Journal of Environmental Sciences2022，34，12： | 2 |
| 10 | Creating burdock polysaccharide-oleanolic acid-ursolic acid nanoparticles to deliver enhanced anti-inflammatory effects:fabrication,structural characterization and property evaluation显示文摘This study explored the potential of polysaccharides from Actium lappa(ALPs)as natural wall materials for producing ALP-based nanoparticles to deliver poorly water-soluble oleanolic acid(OA)and ursolic acid(UA).Encapsulating OA+UA with ALPs(ALP:OA+UA,50:1;OA:UA,1:1)changed the crystalline nature to a more amorphous state through hydrogen bonding and involving O-H/C-O/O-C-O groups.ALP-OA/UA nanoparticles had a particle size and zeta potential(in water)of 199.1 nm/-7.15 mV,with a narrow unimodal size distribution,and excellent pH,salt solution,temperature and storage stability.Compared with ALPs,ALPOA/UA nanoparticles showed enhanced anti-inflammatory activity(especially at a dose of 100μg/mL)in a CuSO-induced zebrafish inflammation model via down-regulating the NF-κB signalling pathway and gene expression of associated transcription factors and cytokines(TNF-α,IL-1βand IL-8).Therefore,ALP-based nanoparticles are natural and anti-inflammatory carriers for hydrophobic bioactive molecules. | Shanshan Zhu Zhichang Qiu Xuguang Qiao Geoffrey I.N.Waterhouse Wenqing Zhu Wenting Zhao Qiuxia He Zhenjia Zheng | 2023 | Food Science and Human Wellness2023，12，2： | 2 |
| 11 | Aequorea taiwanensis n. sp. (Hydrozoa,Leptomedusae) and mtCOI sequence analysis for the genus Aequorea显示文摘Aequorea taiwanensis,a new hydrozoan species from the Taiwan Strait was described using morphological and molecular characteristics.Both morphological and mitochondrial cytochrome oxidase subunit I(mtCOI) data supported A.taiwanensis n.sp.as a valid species.Sequence divergence and genetic distance of A.taiwanensis n.sp.,A.papillata and A.conica were analysed based on the mtCOI gene sequences.The mtCOI sequences from these three species of the genus Aequorea showed high variation frequency,with sequence divergences ranging from 9.10% to 11.9%,and pairwise genetic distances ranging from 0.097 to 0.130.MtCOI sequence analysis provided diagnostic molecular systematic characteristics for accurate identification and discrimination of the species of Aequorea or their populations,and will be used to resolve evolutionary relationships among them.It was suggested that 10%-20% pairwise mtCOI sequence differences indicated the species-level divergence among congeneric species in the Hydromedusae. | ZHENG Lianming LIN Yuanshao LI Shaojing CAO Wenqing XU Zhenzu HUANG Jiaqi | 2009 | Acta Oceanologica Sinica2009，28，1： | 2 |
| 12 | HBeAg induces liver sinusoidal endothelial cell activation to promote intrahepatic CD8 T cell immunity and HBV clearance显示文摘To the Editor It is believed that the inherent tolerogenic property of the liver is involved in the chronicity of hepatitis B virus(HBV)infection[1].However,exposure to HBV in adults usually leads to spontaneous clearance of the virus and the induction of potent and effective anti-HBV T cell immunity in the liver[2],suggesting that the immune microenvironment of the liver switches from limiting to allowing effector T cell responses during acute resolution of HBV infection. | Xiaohong Xie Jinzhuo Luo Ruth Broering Dan Zhu Wenqing Zhou Mengji Lu Xin Zheng Ulf Dittmer Dongliang Yang Jia Liu | 2021 | Cellular & Molecular Immunology2021，18，11： | 1 |
| 13 | Fe-doped NiCo_(2)O_(4)hollow hierarchical sphere as an efficient electrocatalyst for oxygen evolution reaction显示文摘We prepared porous Fe-doped nickel cobaltate(Fe-NiCo_(2)O_(4))hollow hierarchical nanospheres through a facile self-templated synthetic strategy.Due to the porous hollow structure and composition,the Fe-NiCo_(2)O_(4)presented vastly superior electrocatalytic activity for the oxygen evolution reaction(OER),compared with NiCo_(2)O_(4)and the majority of other OER catalysts.With an aim of stimulating a current density of 10 mA$cm-2,the Fe-NiCo_(2)O_(4)catalyst needs an overpotential of 210 mV,which is on a par with the general properties of commercial IrO2.In addition,the Fe-NiCo_(2)O_(4)catalyst performed stably in long-term testing.The excellent activity and long-term stability showed that such catalysts have great promise for widespread application in the field of water splitting. | Wenqing ZHENG Han SUN Xinping LI Shu ZHANG Zhuoxun YIN Wei CHEN Yang ZHOU | 2021 | Frontiers of Materials Science2021，15，4： | 1 |
| 14 | Synthesis of flowe-like CuO nanostructures as a sensitive sensor for catalysis显示文摘 | Teng Fei Yao Wenqing Zheng Youfei | 2008 | Sensors and Actuators B:Chemical2008，134，： | 1 |
| 15 | Synthesis of flower-like CuO nanostructures as a sensitive sensor for catalysis显示文摘 | TENG FEI YAO WENQING ZHENG YOUFEI | 2008 | Sensors and Actuators B:Chemical2008，134，2： | 1 |
| 16 | Classification of two species of Bidens based on discrete stationary wavelet transform extraction of FTIR spectra combined with probability neural network显示文摘 | Cungui Cheng Jia Liu Wenqing Cao Renwei Zheng Hong Wang Changjiang Zhang | 2010 | Vibrational Spectroscopy2010，，1： | 1 |
| 17 | Synthesis of flower-like CuO nanostructures as a sensitive sensor for catalysis显示文摘 | Teng Fei Yao Wenqing Zheng Youfei | 2008 | Sensors and Actuators B:Chemical2008，134，2： | 1 |
| 18 | 显示文摘 | Zheng Xinyou Zhu Wenqing Wu Youzhi | 2004 | Acta Optica Sinica2004，，： | 1 |
| 19 | An Interactive Image Segmentation Algorithm Based on Graph Cut显示文摘 | Qiuhua Zheng Wenqing Li Weihua Hu Guohua Wu | 2012 | Procedia Engineering2012，，： | 1 |
| 20 | Image-Aided Analysis of Ballast Particle Movement Along a High-Speed Railway显示文摘As a core infrastructure of high-speed railways,ballast layers constituted by graded crushed stones feature noteworthy particle movement compared with normal railways,which may cause excessive settlement and have detrimental effects on train operation.However,the movement behavior remains ambiguous due to a lack of effective measurement approaches and analytical methods.In this study,an image-aided technique was developed in a full-scale model test using digital cameras and a colorbased identification approach.A total of 1274 surface ballast particles were manually dyed by discernible colors to serve as tracers in the test.The movements of the surface ballast particles were tracked using the varied pixels displaying tracers in the photos that were intermittently taken during the test in the perpendicular direction.The movement behavior of ballast particles under different combinations of train speeds and axle loads was quantitatively evaluated.The obtained results indicated that the surface ballast particle movements were slight,mainly concentrated near sleepers under low-speed train loads and greatly amplified and extended to the whole surface when the train speed reached 360 km.h-1.Additionally,the development of ballast particle displacement statistically resembled its rotation.Track vibration contributed to the movements of ballast particles,which specifically were driven by vertical acceleration near the track center and horizontal acceleration at the track edge.Furthermore,the development trends of ballast particle movements and track settlement under long-term train loading were similar,and both stabilized at nearly the same time.The track performance,including the vibration characteristics,accumulated settlement,and sleeper support stiffness,was determined to be closely related to the direction and distribution of ballast particle flow,which partly deteriorated under high-speed train loads. | Xuecheng Bian Wenqing Cai Zheng Luo Chuang Zhao Yunmin Chen | 2023 | Engineering2023，，8： | 0 |
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