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| 1 | In vitro antioxidant and anti-inflammatory activities of Korean blueberry(Vaccinium corymbosum L.) extracts显示文摘Objective:To investigate in vitro antioxidant and anti-inflammatory activities of Korean blueberry(Vaccinium corymbosum L.).Methods:Total phenolic and flavonoid contents of the Korean blueberry water and ethanol extracts were determined before determining the potential of the extracts as antioxidant.Antioxidant activity of the extracts was determined by following some well established methods for free radical scavenging such as 2,2-diphenyl-picrylhydrazyl hydrate,1,2,2-azinobis-(3-ethylbenzothiazoline-6-sulfonicacid),free radical induced DNA damage,superoxide dismutaselike and catalase assay etc.Furthermore,1-(4,5-dimethylthiazol-2-yl)-3,5-diphenylformazan and nitric oxide assay were performed to determine the anti-inflammatory activity of the extracts.Results:Total phenolic contents were found(115.0±3.0) and(4.2±3.0) mg GAE/100 g fresh mass for both extracts,respectively and flavonoid contents were(1 942.8±7.0) and(1 292.1±6.0) mg CE/100 g fresh mass for water and ethonal extracts,respectively.Both the extracts displayed significant scavenging activity of some radicals such as 2,2-diphenyl-picrylhydrazyl hydrate(IC_(50) at 1.8 mg/mL and 2.05 mg/mL,respectively),l,2,2-azinobis-(3-ethylbenzothiazoline-6-sulfonicacid)(IC_(50) at1.5 mg/mL and 1.6 mg/mL,respectively) and nitrite(IC_(50) at 1.7 mg/mL and 1.5 mg/mL,respectively)etc.The extracts were found to prevent inflammation as well by reducing nitric oxide production and cytotoxicity in cell.Conclusions:The findings suggest that the fresh Korean blueberry could be used as a source of natural antioxidants and anti-inflammatory agents. | Nadira Binte Samad Trishna Debnath Michael Ye Md.Abul Hasnat Beong Ou Lim | 2014 | Asian Pacific Journal of Tropical Biomedicine2014,4,10: | 6 |
| 2 | Phenolic Contents, Antioxidant and Anti‐inflammatory Activities of Asparagus cochinchinensis ( L oureiro) M errill显示文摘 | Nadira Binte Samad Trishna Debnath Md. Abul Hasnat Mehnaz Pervin Da Hye Kim Jeong Eun Jo Sa Ra Park Beong Ou Lim | 2014 | Journal of Food Biochemistry2014,,1: | 1 |
| 3 | ANTIOXIDANT ACTIVITY OF BENINCASA HISPIDA SEEDS显示文摘 | NADIRA BINTE SAMAD TRISHNA DEBNATH HAI LAN JIN BO RAM LEE PYO JAM PARK SEUNG YUAN LEE BEONG OU LIM | 2013 | Journal of Food Biochemistry2013,,4: | 1 |
| 4 | ANTIOXIDANT POTENTIAL AND OXIDATIVE DNA DAMAGE PREVENTIVE ACTIVITY OF CHRYSANTHEMUM INDICUM EXTRACTS显示文摘 | TRISHNA DEBNATH HAI LAN JIN MD ABUL HASNAT YUNSUK KIM NADIRA BINTE SAMAD PYO‐JAM PARK BEONG OU LIM | 2013 | Journal of Food Biochemistry2013,,4: | 1 |
| 5 | ANTIOXIDANT ACTIVITY OF INONOTUS OBLIQUUS GROWN ON GERMINATED BROWN RICE EXTRACTS显示文摘 | TRISHNA DEBNATH DONG KI PARK BO RAM LEE HAI LAN JIN SEUNG YUAN LEE NADIRA BINTE SAMAD BEONG OU LIM | 2013 | Journal of Food Biochemistry2013,,4: | 1 |
| 6 | Antioxidant activity of Gardenia jasminoides Ellis fruit extracts显示文摘 | Trishna Debnath Pyo-Jam Park Narayan Chandra Deb Nath Nadira Binte Samad Hee Won Park Beong Ou Lim | 2011 | Food Chemistry2011,,3: | 1 |
| 7 | Pickering emulsions stabilized by nanoparticles with thermally responsive grafted polymer brushes显示文摘 | Trishna S Hong C D Krzyszt M | 2010 | Langmuir2010,26,15: | 1 |
| 8 | Antioxidant activity of Gardenia jasminoides Ellis fruit extracts显示文摘 | Trishna Debnath Pyo-Jam Park Narayan Chandra Deb Nath Nadira Binte Samad Hee Won Park Beong Ou Lim | 2011 | Food Chemistry2011,,3: | 1 |
| 9 | Antioxidant activity of Gardenia jasminoides Ellis fruit extracts 显示文摘 | Trishna D Pyo-Jam P NarayanB S | 2011 | Food Chemistry2011,128,: | 1 |
| 10 | Pickering emulsions stabilized by nanoparticles with thermally responsive grafted polymer brushes显示文摘 | Trishna Saigal Dong Hongchen Krzysztof Matyjaszewski | 2010 | Langmuir2010,26,15: | 1 |
| 11 | Emergence of staphylococcal cassette chromosome mec type Ⅰ with high-level mupirocin resistance among methicillin-resistant Staphylococcus aureus显示文摘Objective: To investigate the molecular epidemiology and antimicrobial resistance patterns of methicillin-resistant Staphylococcus aureus(MRSA) among healthcare workers and patients.Methods: MRSA isolates were recovered from nasal swabs collected at a tertiary care hospital of Nepal and confirmed on the basis of Gram staining, conventional biochemical tests, and PCR amplification of mec A gene. PCRs were also used for detection of the different resistance genes and staphylococcal cassette chromosome(SCC) mec types.Antibiotic susceptibility patterns of isolates were assessed by disc diffusion method and minimum inhibitory concentrations were determined by E-test.Results: A total of 29 MRSA were isolated from 536 nasal swabs(5.4%) of health care workers and patients at a tertiary care hospital in Nepal. All isolates were susceptible to amikacin, gentamicin, vancomycin(minimal inhibitory concentrations < 2 mg/m L), tigecycline, tetracycline, nitrofurantoin, rifampicin, quinupristin-dalfopristin, and linezolid. Among the 29 MRSA isolates, resistance to erythromycin(72%), ciprofloxacin(75%), co-trimoxazole(62%), clindamycin(10%), and chloramphenicol(10%) was found, and fifteen isolates(51%)exhibited high-level mupirocin resistance(minimal inhibitory concentrations > 1 024 mg/m L).Fourteen isolates were found harboring the mup A gene and one isolate was found carrying the novel mup B gene. High prevalence(68%) of SCCmec I type was found, followed by SCCmec V(13%) and SCCmec III(3%) among all the MRSA isolates.Conclusions: We found the emergence of SCCmec type I with high-level mupirocin resistance among MRSA in Nepal. Data also suggest that MRSA SCCmec type V strain has spread from the community to the hospital. | Prabhu Raj Joshi Mahesh Acharya Rajan Aryal Kamal Thapa Trishna Kakshapati Rathanin Seng Anjana Singh Sutthirat Sitthisak | 2017 | Asian Pacific Journal of Tropical Biomedicine2017,7,3: | 0 |