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| 1 | Suppression of Meloidogyne javanica by antagonistic and plant growth-promoting rhizobacteria显示文摘Four rhizobacteria selected out of over 500 isolates from rhizosphere of the vegetables in China were further studied for suppression of the root-knot nematode and soil-borne fungal pathogens in laboratory and greenhouse in Belgium. They were identified as Brevibacillus brevis or Bacillus subtilis by Biolog test and partial 16s rDNA sequence comparison. They not only inhibited the radial growth of the root-infecting fungi Rhizoctonia solani SX-6, Pythium aphanidermatum ZJP-1 and Fusarium oxysporum f.sp. cucumerinum ZJF-2 in vitro, but also exhibited strong nematicidal activity by killing the second stage larvae of Meloidogyne javanica to varying degrees in the greenhouse. The toxic principles of bacterium B7 that showed the highest juvenile mortality were partially characterized. The active factors were heat stability and resistance to extreme pH values. B7 used either as seed dressing or soil drench significantly reduced the nematode populations in the rhizosphere and enhanced the growth of mungbean plants over the controls in the presence or absence of R. solani. | 李斌 谢关林 SOAD A COOSEMANS J | 2005 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2005，6，6： | 6 |
| 2 | Phytochemical studies and anti-ulcerative colitis effect of Moringa oleifera seeds and Egyptian propolis methanol extracts in a rat model显示文摘Objective: To analyze the phytochemical constituents, and to explore potential protective effect of the methanol extract of Moringa oleifera(M. oleifera) seeds and Egyptian propolis, each alone or concurrently administered on acetic acid-induced ulcerative colitis in rats. Methods: Eight groups of 5 rats each were used: normal control group with distilled water, model group, two groups with M. oleifera seeds(100 and 200 mg/kg), two groups with propolis(50 and 100 mg/kg), one group with concurrent administration of both, and one group with prednisolone(reference drug). Macro-and microscopic picture, ulcer index and lesion scores, oxidative markers, inflammatory mediators, in vitro activity of the inflammatory enzymes and 1, 1-diphenyl-2-picrylhydrazyl free radicals scavenging activity were evaluated. The phytochemical constituents of both extracts were explored by GC-MS analysis. Results: Both treatments modulated the macro-and microscopic picture, decreased the ulcerative index, lesion score, oxidative markers and inflammatory mediators, and inhibited the COX-1 and COX-2 enzymes. Propolis appeared to be powerful free radicals scavenger. A powerful synergistic effect of both treatments in modulating the course of the disease was reported. GCMS analysis of methanol extract of M. oleifera seeds and propolis revealed the presence of 50 and 34 compounds, respectively. Conclusions: M. oleifera seeds and propolis methanol extracts have modulated the course of acetic acid-induced ulcerative colitis. Moreover, both treatments induce a good synergistic effect against the disease. Isolation of the active constituents is recommended. | Attia H.Atta Samar M.Mouneir Soad M.Nasr Doaa Sedky Amany M.Mohamed Shimaa A.Atta Hassan Mohamed Desouky | 2019 | Asian Pacific Journal of Tropical Biomedicine2019，9，3： | 4 |
| 3 | Anti-hyperglycemic activity of the leaves of Tetracera scandens Linn. Merr. (Dilleniaceae) in alloxan induced diabetic rats显示文摘 | Abdulrashid Umar Qamar U. Ahmed Bala Y. Muhammad Bashar Bello S. Dogarai Siti Zaiton Bt. Mat Soad | 2010 | Journal of Ethnopharmacology2010，，1： | 2 |
| 4 | Different pathways for sodium entry in cardiac cells during ischemia and early reperfusion显示文摘 | Delphine Baetz Monique Bernard Caroline Pinet Sophie Tamareille Soad Chattou Houda El Banani Alain Coulombe Danielle Feuvray | 2003 | Molecular and Cellular Biochemistry (-)2003，，1： | 2 |
| 5 | Anti-hyperglycemic activity of the leaves of Tetracera scandens Linn. Merr. (Dilleniaceae) in alloxan induced diabetic rats显示文摘 | Abdulrashid Umar Qamar U. Ahmed Bala Y. Muhammad Bashar Bello S. Dogarai Siti Zaiton Bt. Mat Soad | 2010 | Journal of Ethnopharmacology2010，，1： | 2 |
| 6 | Sesamol Alleviates the Cytotoxic Effect of Cyclophosphamide on Normal Human Lung WI-38 Cells via Suppressing RAGE/NF-κB/Autophagy Signaling显示文摘Cyclophosphamide(CYL)is a chemotherapeutic medication commonly used in managing various malignancies like breast cancer or leukemia.Though,CYL has been documented to induce lung toxicity.Mechanism of CYL toxicity is through oxidative stress and the release of damage-associated molecular patterns(DAMPs).Sesamol(SES)is a natural antioxidant isolated from Sesamum indicum and its effect against CYL-induced lung toxicity is not studied yet.This study aims to inves-tigate whether SES could prevent any deleterious effects induced by CYL on lung using normal human lung cells,WI-38 cell line,without suppressing its efficacy.Cells were pretreated with SES and/or CYL for 24 h,then cell viability was estimated by MTS and trypan blue assays.The mode of cell death was determined by AO/EB staining.Additionally,caspase-3 level,oxidative stress,and inflammatory markers were evaluated by colorimetric and ELISA techniques.qRT-PCR was performed to evaluate RAGE,NF-κB,and Beclin-1 mRNA-expression.CYL-treated WI-38 cells developed a significantly increased cell death with enhanced oxidative and RAGE/NF-κb/Autophagy signaling,which were all attenuated after pretreatment with SES.Thus,we concluded that SES offered a protective role against CYL-induced lung injury via suppressing oxidative stress and RAGE/NF-κB/Autophagy signaling,which is a natural safe therapeutic option against CYL toxicities. | Soad Z.El-Emam | 2021 | Natural Products and Bioprospecting2021，11，3： | 2 |
| 7 | Protective Effect of Egyptian Propolis against Rabbit Pasteurellosis显示文摘 | Somia A. Nassar Amira H. Mohamed Hamdy Soufy Soad M. Nasr Stelvio M. Bandiera | 2013 | BioMed Research International2013，，： | 1 |
| 8 | Phytochemical, antioxidant and hepatoprotective effects of different fractions of Moringa oleifera leaves methanol extract against liver injury in animal model显示文摘Objective: To evaluate the potential antioxidant and hepatoprotective effects of n-hexane, dichloromethane(DCM), ethyl acetate(EtOAc), n-butanol and aqueous fractions of Moringa oleifera(M. oleifera) leaves methanol extract against carbon tetrachloride(CCl_4)-induced liver injury in rats. Methods: These fractions were prepared from the M. oleifera leaves methanol extract by solubilization in water and partitioning in n-hexane, EtOAc, DCM and n-butanol. Their phyto-components were identified by GC-MS analysis. The in vitro antioxidant effect of these fractions was carried out by assessment of 1,1-diphenyl-2-picrylhydrazyl scavenging activity. A total of 40 Sprague Dawley rats were allocated into 8 equal groups: group 1 given olive oil(1 m L/kg b.wt.), group 2 injected with CCl_4, group 3 to 7 administered with n-hexane, DCM, EtOAc, n-butanol and aqueous fractions, respectively after CCl_4, group 8 administered with silymarin after CCl_4. The activities of aspartate aminotransferase, alanine aminotransferase, and the levels of total cholesterol, triglycerides, glucose, total proteins and albumin in serum were determined spectrophotometrically. Glutathione reduced, lipid peroxide by-products levels, glutathione-s-transferase and catalase enzyme activities in the liver homogenate were determined by spectrophotometer. Liver specimens were also examined for histopathological alterations under light microscope. Results: The GCMS analysis of different fractions of the M. oleifera leaves methanol extract revealed that n-hexane, DCM, EtOAc, n-butanol, and aqueous fractions contained 17, 22, 23, 19 and 32 compounds, respectively. The percent and the molecular structure of each component in each fraction were identified. The n-butanol and EtOAc fractions exhibited the strongest in vitro antioxidant activity against 1,1-diphenyl-2-picrylhydrazyl. CCl_4 significantly decreased glutathione reduced and total proteins concentration and glutathione-s-transferase and catalase activities but increased lipid peroxide by-products and total cholesterol levels. The n-hexane followed by aqueous and DCM fractions were the most potent to regulate serum enzyme activities and lipid peroxide by-products levels in the liver homogenate. Conclusions: n-hexane, DCM, and aqueous fractions have the highest effectiveness against CCl_4-induced hepatotoxicity. Isolation and purification of the active constituents require further experiments. | Attia H.Atta Soad M.Nasr Abduljalil H.Almaweri Doaa Sedky Amany M.Mohamed Hassan M.Desouky Mostafa A.Shalaby | 2018 | Asian Pacific Journal of Tropical Medicine2018，11，7： | 1 |
| 9 | Protective effect of whey proteins against nonalcoholic fatty liver in rats显示文摘 | Essam M Soad H Abdel-Gawad I | | 0，，： | 1 |
| 10 | CorreIation between viral load of HBV in chronic hepatitis B patients and pre- core and basal core promoter mutations显示文摘 | Soad G Zohreh S Seyed MH | 2013 | Hepat Mon2013，13，2： | 1 |
| 11 | New rapid validated HPTLC method for the determination of galanthamine in Amaryllidaceae plant extracts显示文摘 | AMINA H SOAD M HALA M | 2008 | Phytochemical Analysis2008，19，4： | 1 |
| 12 | physioloigical insulinemia acutely modulates plasma leptin显示文摘 | Soad MF | 1998 | Diabetes1998，47，： | 1 |
| 13 | Protective effect of Jasonia montana against ethinylestradiol-induced cholestasis in rats显示文摘 | Mohammed A. Hussein Soad M. Abdel-Gawad | 2009 | Saudi Pharmaceutical Journal2009，，1： | 1 |
| 14 | Genetic factors weight in as clues to obesity显示文摘 | Soad MF Wabitsch M Jensen PB | 1998 | Diabetes1998，47，3： | 1 |
| 15 | QUANTITATIVE, QUALITATIVE AND TOXIGENIC EVALUATIONS OF XEROPHILIC MOLD IN TRADITIONAL EGYPTIAN SALTED FISH, MOLOUHA显示文摘 | ALI MEAWADAHMED SOAD AHMEDISMAIL HOSNY ABD‐EL‐LATIEFABD‐EL‐RAHMAN | 2005 | Journal of Food Safety2005，，1： | 1 |
| 16 | Analysis of fine structure and biochemical changes of retina during aging of W istar albino rats显示文摘 | Hassan IH El‐Sayyad Soad A Khalifa Fawkia I El‐Sayyad Shaker A Mousa Ezaldin AM Mohammed | 2014 | Clin Experiment Ophthalmol2014，，2： | 1 |
| 17 | Home countries’ determinants of outward foreign direct investment in developing economies:Malaysian Case显示文摘 | Rosfadzimi Mat Soad & Abd Halim Mohd Noor | 2011 | Prosiding Rerkem2011，，2： | 1 |
| 18 | Physioloigical insulinemia acutely modulates plasma leptin显示文摘 | SOAD MF | 1998 | Diabetes1998，47，： | 1 |
| 19 | Functional role of matrix rnetalloproteinases in ouarian tumor plasticity 显示文摘 | Soad AK Fletcher MS Coffin JE | 2004 | Am J Obstet Gyneol2004，190，4： | 1 |
| 20 | Vitamin D Supplementation in Infants With Chronic Congestive Heart Failure显示文摘 | Soad Shedeed | 2012 | Pediatric Cardiology2012，，5： | 1 |
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