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| 1 | 植物表型组学:发展、现状与挑战显示文摘随着遥感、机器人技术、计算机视觉和人工智能的发展,植物表型组学研究已经步入了快速成长阶段。本文首先介绍了植物表型组学的发展简史,包括其理论核心、研究方法、在生物研究中的应用以及国际上最新的研究动向。然后,针对各类表型技术载体平台如手持、人载、车载、田间实时监控、大型室内外自动化平台和航空机载等,分析这些技术手段在室内、外植物研究中的应用情况和实际问题。为了对表型研究中产生的巨量图像和传感器数据进行量化分析,把大数据转化为有实际意义的性状信息和生物学知识,本文着重讨论了后期表型数据解析和相应的研发过程。最后,提出表型组学的应用前景与未来展望,以期为中国的表型研究提供指导和建议。 | 周济 Francois Tardieu Tony Pridmore John Doonan Daniel Reynolds Neil Hall Simon Griffiths 程涛 朱艳 王秀娥 姜东 丁艳锋 | 2018 | 南京农业大学学报2018，41，4： | 64 |
| 2 | Identification of Differentially Senescing Mutants of Wheat and Impacts on Yield,Biomass and Nitrogen Partitioning显示文摘Increasing photosynthetic capacity by extending canopy longevity during grain filling using slow senescing stay-green genotypes is a possible means to improve yield in wheat. Ethyl methanesulfonate (EMS) mutated wheat lines (Triticum aestivum L. cv. Paragon) were screened for fast and slow canopy senescence to investigate the impact on yield and nitrogen partitioning. Stay-green and fast-senescing lines with similar anthesis dates were characterised in detail. Delayed senescence was only apparent at higher nitrogen supply with low nitrogen supply enhancing the rate of senescence in all lines. In the stay-green line 3 (SG3), on a whole plant basis, tiller and seed number increased whilst thousand grain weight (TGW) decreased; although a greater N uptake was observed in the main tiller, yield was not affected. In fast-senescing line 2 (FS2), yield decreased, principally as a result of decreased TGW. Analysis of N-partitioning in the main stem indicated that although the slow-senescing line had lower biomass and consequently less nitrogen in all plant parts, the proportion of biomass and nitrogen in the flag leaf was greater at anthesis compared to the other lines; this contributed to the grain N and yield of the slow-senescing line at maturity in both the main tiller and in the whole plant. A field trial confirmed senescence patterns of the two lines, and the negative impact on yield for FS2 and a positive impact for SG3 at low N only. The lack of increased yield in the slow-senescing line was likely due to decreased biomass and additionally a possible sink limitation. | Adinda P.Derkx Simon Orford Simon Griffiths M.John Foulkes Malcolm J. Hawkesford | 2012 | Journal of Integrative Plant Biology2012，54，8： | 9 |
| 3 | An Exploration of Deep-Learning Based Phenotypic Analysis to Detect Spike Regions in Field Conditions for UK Bread Wheat显示文摘Wheat is one of the major crops in the world,with a global demand expected to reach 850 million tons by 2050 that is clearly outpacing current supply.The continual pressure to sustain wheat yield due to the world’s growing population under fluctuating climate conditions requires breeders to increase yield and yield stability across environments.We are working to integrate deep learning into field-based phenotypic analysis to assist breeders in this endeavour.We have utilised wheat images collected by distributed CropQuant phenotyping workstations deployed for multiyear field experiments of UK bread wheat varieties.Based on these image series,we have developed a deep-learning based analysis pipeline to segment spike regions from complicated backgrounds.As a first step towards robust measurement of key yield traits in the field,we present a promising approach that employ Fully Convolutional Network(FCN)to performsemantic segmentation of images to segment wheat spike regions.We also demonstrate the benefits of transfer learning through the use of parameters obtained from other image datasets.We found that the FCN architecture had achieved a Mean classification Accuracy(MA)>82%on validation data and>76%on test data and Mean Intersection over Union value(MIoU)>73%on validation data and and>64%on test datasets.Through this phenomics research,we trust our attempt is likely to form a sound foundation for extracting key yield-related traits such as spikes per unit area and spikelet number per spike,which can be used to assist yield-focused wheat breeding objectives in near future. | Tahani Alkhudaydi Daniel Reynolds Simon Griffiths Ji Zhou Beatriz de la Iglesia | 2019 | Plant Phenomics2019，1，1： | 5 |
| 4 | Invasion genetics: Lessons from a ubiquitous bird, the house sparrow Passer domesticus显示文摘 | Andrea L. LIEBL Aaron W. SCHREY Samuel C. ANDREW Elizabeth L.SHELDON Simon C. GRIFFITH | 2015 | Current Zoology2015，61，3： | 4 |
| 5 | Role of neutrophils in BCG immunotherapy for bladder cancer 显示文摘 | Simons MP O'Donnell MA Griffith TS | 2008 | Urol Oncol2008，26，4： | 1 |
| 6 | Neutrophils and TRAIL:insights into BCG immunotherapy for bladder can- cer显示文摘 | Simons MP Nauseef WM Griffith TS | 2007 | Immunol Res2007，39，13： | 1 |
| 7 | Hydrophobic layers and epicuticular wax powders in Bromelaceae显示文摘 | SIMON PIERCE KATE MAXWELL HOWARD GRIFFITHS | 2001 | American Journal of Botany2001，88，8： | 1 |
| 8 | Role of neutrophils in BCG immunotherapy for bladder cancer显示文摘 | Mark P. Simons Michael A. O’Donnell Thomas S. Griffith | 2008 | Urologic Oncology: Seminars and Original Investigations2008，，4： | 1 |
| 9 | Barrett’s esophagus: cancer and molecular biology显示文摘 | Michael K. Gibson Arashinder S. Dhaliwal Nicholas J. Clemons Wayne A. Phillips Katerina Dvorak Daniel Tong Simon Law E. Daniel Pirchi Jari R?s?nen Mark J. Krasna Kaushal Parikh Kausilia K. Krishnadath Yu Chen Leonard Griffiths Benjamin J. Colleypriest J. | 2013 | Ann NY Acad Sci2013，，1： | 1 |
| 10 | Enantioselective hydrogenation显示文摘 | Slipszenko J A Griffiths S P Simons K E | 1998 | Journal of Catalysts1998，179，： | 1 |
| 11 | Calcium overload in selectively vulnerable neurons of the hippocampus during and after ischemia: an electron microscopy study in the rat 显示文摘 | SIMON RP GRIFFITHS T EVANS MC | 1984 | J Cereb Blood Flow Metab1984，4，3： | 1 |
| 12 | A Pseudo-Response Regulator is misexpressed in the photoperiod insensitive Ppd-D1a mutant of wheat (Triticum aestivum L.)显示文摘 | James Beales Adrian Turner Simon Griffiths John W. Snape David A. Laurie | 2007 | Theoretical and Applied Genetics2007，，5： | 1 |
| 13 | Construction and analysis of a BAC library in the grass Brachypodium sylvaticum: its use as a tool to bridge the gap between rice and wheat in elucidating gene content显示文摘 | Tracie N. Foote Simon Griffiths Sebastien Allouis Graham Moore | 2004 | Functional & Integrative Genomics2004，，1： | 1 |
| 14 | Neutrophils and TRAIL: insights into BCG immunotherapy for bladder cancer显示文摘 | Mark P. Simons William M. Nauseef Thomas S. Griffith | 2007 | Immunologic Research (-)2007，，1： | 1 |
| 15 | Barrett’s esophagus: cancer and molecular biology显示文摘 | Michael K. Gibson Arashinder S. Dhaliwal Nicholas J. Clemons Wayne A. Phillips Katerina Dvorak Daniel Tong Simon Law E. Daniel Pirchi Jari R?s?nen Mark J. Krasna Kaushal Parikh Kausilia K. Krishnadath Yu Chen Leonard Griffiths Benjamin J. Colleypriest J. | 2013 | Ann. N.Y. Acad. Sci2013，，1： | 1 |
| 16 | Enantioselective hydrogenation显示文摘 | Slipszenko J A Griffiths S P Simons K E | 1998 | Journal of Catalysts1998，179，7： | 1 |
| 17 | Blockade of N-methyl- D-aspartate receptors may protect against ischemic damage in the brain显示文摘 | Simon RP Swan JH Griffiths T | 1984 | Science1984，226，4676： | 1 |
| 18 | Molecular characterization of transforming plasmind rearrangements in transgenic rice reveals a recombination hotspots in the CaMV 35S promoter and confirms the predominance of micohomology mediated recombination显示文摘 | Ajay Kohli Simon Griffiths Natalia Palacios | 1999 | The Plant J1999，17，6： | 1 |
| 19 | Neutrophils and TRAIL: insight into BCG immunotherapy for bladder cancer 显示文摘 | Simons MP Nauseef WM Griffith TS | 2007 | Immuno Res2007，39，13： | 1 |
| 20 | Identifying wheat genomic regions for improving grain protein concentration independently of grain yield using multiple inter-related populations显示文摘 | Matthieu Bogard Vincent Allard Pierre Martre Emmanuel Heumez John W. Snape Simon Orford Simon Griffiths Oorbessy Gaju John Foulkes Jacques Gouis | 2013 | Molecular Breeding2013，，3： | 1 |
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