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| 1 | Characteristics of Rat Lumbar Vertebral Body Bone Mineral Density and Differential Segmental Responses to Sex Hormone Deficiency:a Clinical Multidetector Computed Tomography Study显示文摘Objective To investigate sex hormone deficiency related osteoporosis and efficacy of different therapies. Methods Orchiectomized and ovariectomized rat models are used to investigate sex hormone deficiency related osteoporosis and efficacy of different therapies. A rat vertebral body can be longitudinally divided into central portion, which contain more trabecular bone, and para-endplate portions which contain more compact bone. In matured male and female Wistar and Sprague-Dawley rat lumbar spines, we investigated baseline bone mineral density (BMD) characteristics and the differential segmental responses in bone loss within the lumbar vertebral body post gonadal surgery with clinical multidetector computed tomography. Results Para-endplate sections had a higher BMD than central sections. The cephalad para-endplate sections had a higher BMD than the caudad para-endplate sections. Eight weeks after gonadal removal, there was more bone loss in central sections than para-endplate sections. The relative difference of bone loss between para-endplate and central sections was more apparent in male rats than in female rats. There was more bone loss in caudad sections than cephalad sections; this lead to a further increase of BMD difference between caudad para-endplate sections and cephalad para-endplate sections post gonadal surgery. Conclusion The approach described in this study provided a consistent way to study BMD change within predominantly compact bone portion and trabecular bone portion of the vertebral body. | DENG Min WANG Yi Xiang James F. GRIFFITH LU Gang Anil T AHUJA POON Wai S | 2012 | Biomedical and Environmental Sciences2012，25，6： | 2 |
| 2 | Fas ligand-induced apoptosis as a mechanism of immune privilege显示文摘 | Griffith T S Brunner T Fletcher S M | | 0，，： | 2 |
| 3 | Virtu-alness and Knowledge in Teams:Managing the Love Triangle of Organizations,Individuals,And Information Technology 显示文摘 | GRIFFITH T L SAWYER J E NEALE M A | 2003 | MIS Quarterly2003，，2： | 1 |
| 4 | Pure hemozoin is inflammatory in vivo and activates the NALP3 inflammasome via release of uric acid 显示文摘 | Griffith JW Sun T McIntosh MT | 2009 | J Immunol2009，183，8： | 1 |
| 5 | Fas ligand-induced apoptosis as a mechanism of immune privilege显示文摘 | Griffith TS Brunner T Fletcher SM | 1995 | Science1995，270，5239： | 1 |
| 6 | An official ATS/IDSA statement:diagnosis,treatment,and prevention of nontuberculous mycobacterial diseases显示文摘 | Griffith DE Aksamit T Brown-Elliott BA | | 0，，04： | 1 |
| 7 | Learning author-topic models from text corpora显示文摘 | Rosen-Zvi M Chemudugunta C Griffiths T | | 0，，： | 1 |
| 8 | Probabilistic topic models 显示文摘 | Steyvers M Griffiths T L | 2007 | Handbook of Latent Semantic Analysis2007，427，7： | 1 |
| 9 | A framework for biological criteria for Florida streams using benthic macroinvertebrates 显示文摘 | BARBOUR M T GERRITSEN J GRIFFITH G E | 1996 | Journal of the North American Benthological Society1996，15，2： | 1 |
| 10 | A framework for biological criteria for Florida streams using benthic macroinvertebrates显示文摘 | Barbour M T Gerritsen J Griffith G E | 1996 | Journal of the North American Benthological Society1996，15，： | 1 |
| 11 | Assessment of cerebral haemodynamics and vascular reserve in patients with symptomatic carotid artery occlusion: an integrated MR method 显示文摘 | GRIFFITHS PD GAINES P CLEVELAND T | 2005 | Neuroradiology2005，47，3： | 1 |
| 12 | Why New Technologies Fail显示文摘 | Griffith T L Zammuto R F Aiman-Smith L | 1999 | Industrial Management1999，41，3： | 1 |
| 13 | Teallach: A Model-Based User Interface Development Environment for Object显示文摘 | GRIFFITHS T BARCLAY PJ | 2001 | Interacting with Computers2001，14，1： | 1 |
| 14 | Evolution of quasiparticle charge in the fractional quantum hall regime 显示文摘 | Griffiths T G Comforti E Heiblum M | 2000 | Phvs Rev Lett2000，85，18： | 1 |
| 15 | How to Grow a Mind: Statistics, Structure, and Abstraction 显示文摘 | Tenenbaum J Kemp C Griffiths T | 2011 | Science2011，，12： | 1 |
| 16 | Lipid productivity as a key characteristic for choosing algal species for biodiesel production显示文摘 | Griffiths M J Harrison S T L | 2009 | J Appl Phyco12009，21，： | 1 |
| 17 | Cortical activation during perception of a rotating wide-field acoustic stimulus显示文摘 | GRIFFITHS T D GREEN G G | 1999 | Neuroimage1999，10，： | 1 |
| 18 | Molecular characteriza tion of Phl as a major chromosome pairing locus in polyploid wheat显示文摘 | Griffiths S Sharp R Foote T N etal | 2006 | Nature2006，439，： | 1 |
| 19 | Fas ligand-induced apoptosis as a mechanism of immune privilege显示文摘 | Griffith TS Brunner T Fletcher SM | 1995 | Science1995，270，5239： | 1 |
| 20 | The effect of Cd^2+ on the biosynthesis of chlorophyll in leaves of barley plant 显示文摘 | Stobart A K Griffiths W T Ameen B I | 1985 | Plant Physiology1985，63，： | 1 |
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