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| 1 | 2018加拿大心境障碍与焦虑障碍治疗协作组/国际双相障碍学会指南:双相障碍的管理显示文摘加拿大心境障碍与焦虑障碍治疗协作组(Canadian Network for Mood and Anxiety Treatments,CANMAT)曾于2005年发布了第1版双相障碍管理指南,并分别于2007、2009和2013年对该指南进行了更新,其中最近的2次更新是与国际双相障碍学会(International Society for Bipolar Disorders,ISBD)合作完成。2018版CANMAT/ISBD双相障碍治疗指南(以下简称指南)反映了自2005年首版指南发表以来本领域取得的重大进展,包括疾病诊断与疾病管理的更新以及药物治疗与心理治疗的近期研究进展。这些前沿进展中综合考虑了循证证据的级别,并基于治疗疗效、临床实践经验、安全性、耐受性和药物导致的转相风险等,对一线、二线及三线治疗方案进行了简明而清晰的推荐。本指南中新增内容涵盖了双相Ⅰ型障碍(BD-Ⅰ)的躁狂发作急性期、抑郁发作急性期和双相障碍维持期的一线及二线治疗推荐等级划分。这种对治疗推荐等级的划分综合考虑了治疗方法对双相障碍不同时相的影响,将进一步帮助临床医生做出基于循证证据的治疗决策。锂盐、喹硫平、双丙戊酸盐、阿塞那平、阿立哌唑、帕利哌酮、利培酮和卡利拉嗪单药或联合使用被推荐为躁狂发作急性期的一线治疗选择。BD-Ⅰ抑郁期的一线治疗选择包括喹硫平、鲁拉西酮、锂盐、拉莫三嗪单药,鲁拉西酮联合锂盐或双丙戊酸盐或拉莫三嗪辅助治疗。尽管急性期治疗有效的药物通常应继续用于BD-Ⅰ的维持期治疗,但也存在一些特殊情况(例如抗抑郁药)。现有数据表明,锂盐、喹硫平、双丙戊酸盐、拉莫三嗪、阿塞那平和阿立哌唑单药或联合治疗应被视为维持治疗的初始或更换治疗方案时的一线选择。除了探讨BD-Ⅰ的相关问题外,本指南中还对双相Ⅱ型障碍(BD-Ⅱ)的临床管理进行了系统回顾并给予治疗推荐,同时针对特殊人群也有相关推荐,如处于各个生殖周期的女性、儿童、青少年和老年人。此外,本指南中还讨论了特定精神疾病及共病(如物质滥用、焦虑障碍和代谢性疾病)的影响。最后,本指南中概述了安全性和药物监测的相关问题。CANMAT/ISBD工作组希望本指南能够成为全球临床医生的实用工具。 | Lakshmi N Yatham Sidney H Kennedy Sagar V Parikh Ayal Sehaffer David J Bond Benicio N Frey Verinder Sharma Benjamin I Goldstein Soham Rej Serge Beaulieu Martin Alda Glenda MaeQueen Roumen V Milev Arun Ravindran Claire O'Donovan Diane Mclntosh Raymond W Lam Gustavo Vazquez Flavio Kapczinski Roger S Melntyre Jan Kozicky Shigenobu Kanba Beny Lafer Trisha Suppes Joseph R Calabrese Eduard Vieta Gin Malhi Robert M Post Michael Berk 胡晨(译) 王刚(译) | 2019 | 中华精神科杂志2019，52，1： | 25 |
| 2 | Migraine and stroke显示文摘Migraines are generally considered a relatively benign neurological condition.However,research has shown an association between migraines and stroke,and especially between migraine with aura and ischaemic stroke.Patients can also suffer from migrainous infarction,a subset of ischaemic stroke that often occurs in the posterior circulation of younger women.The exact pathogenesis of migrainous infarct is not known,but it is theorised that the duration and local neuronal energy level from cortical spreading depression may be a key factor.Other factors contributing to migrainous infarct may include vascular,inflammatory,endothelial structure,patent foramen ovale,gender,oral contraceptive pill use and smoking.Vasoconstrictors such as the triptan and ergot class are commonly used to treat migraines and may also play a role.Migraine is also shown to be correlated to haemorrhagic stroke,although studies do not demonstrate causation versus association,and further studies are warranted.There are also some rare genetic diseases such as cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy,retinal vasculopathy with cerebral leukodystrophy and others,which can cause both migraines and infarcts.On imaging,many migraineurs are found to have white matter changes similar to those seen in patients with stroke.These may be caused in part by alterations in resting cerebral blood flow and vasoconstrictor use.In treating patients with migraines,it is important to identify and modify any vascular risk factors such as hypertension,smoking,oral contraceptive pill use and lifestyle factors.Further studies will determine if more aggressive treatment of migraines can ultimately lead to fewer strokes in this population. | Yonghua Zhang Aasheeta Parikh Shuo Qian | 2017 | Stroke & Vascular Neurology2017，2，3： | 8 |
| 3 | 载体对其负载的Cu-Co双金属催化剂上5-羟甲基糠醛氢解选择性生成2,5-二甲基呋喃的影响(英文)显示文摘碳-氧键氢解是生物质呋喃基化合物制备交通燃料常见的模型反应,其中5-羟甲基糠醛(HMF)转化为汽油添加剂2,5-二甲基呋喃(DMF)尤为引人关注.本文采用CeO_2,ZrO_2和Al_2O_3负载的Cu-Co双金属催化剂用于HMF选择性氢解制DMF的反应中.采用X射线衍射、N_2吸附-脱附、投射电镜、H_2-程序升温还原、氨-程序升温脱附和元素分析表征了新鲜的和使用过催化剂的结构,并将其与催化活性相关联.Cu-Co/CeO_2催化剂通过在大的Cu颗粒上还原C=O键生成了最多的2,5双(羟甲基呋喃)(BHMF).但Cu-Co/Al_2O_3催化剂具有高度分散的Cu,Cu-Co复合氧化物和大量的弱酸位,因而生成DMF的选择性最高.Cu-Co/ZrO_2催化剂则由于存在强酸位,DMF选择性较低,生成了各种过度氢解产物,如2,5而甲基四氢呋喃和5,5-二(亚甲基)双(2-甲基呋喃).因此,考察了Cu-Co/Al_2O_3催化剂上的反应路径,以及温度、氢气压力和时间等操作条件的影响,使其具有较优的HMF转化率和DMF选择性. | Sanjay Srivastava G.C.Jadeja Jigisha Parikh | 2017 | Chinese Journal of Catalysis2017，38，4： | 4 |
| 4 | Urbanization, energy use and greenhouse effects in economic development显示文摘 | Jyoti Parikh Vibhooti Shukla | 1995 | Global Environmental Change1995，，2： | 3 |
| 5 | Immunohistochemical analysis of the Wnt/β-catenin signaling pathway in pancreatic neuroendocrine neoplasms显示文摘AIM: To investigate the role of the Wnt/β-catenin pathway in pancreatic neuroendocrine neoplasms(PanN ENs). METHODS: Tissue microarrays containing 88 PanN ENs were immunohistochemically labeled with antibodies to β-catenin, E-cadherin, adenomatous polyposis coli(APC), chromogranin and synaptophysin. One case had only metastatic tumors resected, whereas others(n = 87) received pancreatectomy with or without partial hepatectomy. Pathology slides, demographic, clinicopathologic, and follow up data were reviewed. Patients' demographics, clinicopathologic features, and immunohistochemical results from 87 primary tumors were compared between patients with low stage(stage Ⅰ/Ⅱ) and high stage(stage Ⅲ/Ⅳ) tumors. In addition, correlation of immunohistochemical results from primary tumors with disease-specific survival(DSS) was evaluated. RESULTS: Strong membranous β-catenin staining in the primary tumor was observed in all 13 stage Ⅲ/Ⅳ Pan NENs as compared to 47%(35/74) of stage Ⅰ/Ⅱtumors(P < 0.01). However, the strong membranous β-catenin staining was unassociated with tumor grade or DSS. Decreased membranous β-catenin staining was associated with decreased membranous E-cadherin labeling. Nuclear β-catenin staining was seen in 15%(2/13) of stage Ⅲ/Ⅳ Pan NENs as compared to 0%(0/74) of stage Ⅰ/Ⅱ tumors(P = 0.02). The case with metastasectomy only also showed nuclear β-catenin staining. Two of the three cases with nuclear β-catenin staining were familial adenomatous polyposis(FAP) patients. Lack of APC expression was seen in 70%(57/81) of the cases, including the 3 cases with nuclear β-catenin staining. Expression of E-cadherin and APC in primary tumor was not correlated with tumor grade, tumor stage, or disease specific survival. CONCLUSION: The Wnt/β-catenin pathway was altered in some PanN ENs, but did not Impact DSS. PanN ENs in FAP patients demonstrated nuclear β-catenin accumulation and loss of APC. | Vivian Weiss Julie Dueber Jesse P Wright Justin Cates Frank Revetta Alexander A Parikh Nipun B Merchant Chanjuan Shi | 2016 | World Journal of Gastrointestinal Oncology2016，8，8： | 3 |
| 6 | 妊娠并发症及妊娠特点与未来血压升高风险的关系显示文摘妊娠特点与心血管病风险相关,但其与高血压或血压水平的独立关联仍不明确。该研究将瑞典医学出生登记与Vsterbotten(瑞典北部)干预研究数据相联系。纳入妊娠前无高血压的40岁经产女性15 896人,用线性回归和Logistic回归分析以前妊娠因素与血压水平及高血压的关系。妊娠因素包括胎次、首次分娩年龄、子痫前期、妊娠期糖尿病、胎盘早剥、小于胎龄儿(出生体质量〈相同胎龄儿第3百分位)或死胎。 | Parikh NI Norberg M Ingelsson E Cnattingius S Vasan RS Domellf M Jansson JH Edstedt Bonamy AK 赵狄 练桂丽 | 2017 | 中华高血压杂志2017，25，2： | 3 |
| 7 | Improving intermittent androgen deprivation therapy: lessons learned from basic and translational research显示文摘断断续续的雄激素剥夺治疗(IADT ) 在有 nonmetastatic 疾病的前列腺癌症病人是连续雄激素剥夺治疗(ADT ) 的一种选择。ADT 与象热闪光,性机能障碍,贫血症,疲劳,肌肉质量的损失,骨质疏松症,新陈代谢的症候群和早熟的心血管的疾病那样的众多的副作用被联系。IADT 与改进生活并且到前列腺癌症的延期前进的质量到阉割抵抗的意愿被开发。由与 ADT 相比的 IADT 的生活的稍微改进的质量的好处在多重临床的试用被表明。IADT 被注意是到在有前列腺癌症,但是在与变形前列腺癌症在病人执行的研究的生物化学的复发的病人的 ADT 的 noninferior,结果是不确定的。我们的最近的研究建议 5 个 alpha-reductase 禁止者的管理能显著地在 IADT 的离开周期期间延长当离开周期持续时间是短的时,忍受雄激素敏感的前列腺肿瘤的老鼠的幸存。这评论在动物模型和这发现进诊所的潜在的翻译在 IADT 讨论 5 alpha-reductase 抑制的幸存利益。 | Rahul A Parikh Laura E Pascal Benjamin J Davieses Zhou Wang | 2014 | Asian Journal of Andrology2014，16，4： | 2 |
| 8 | A Multicenter Analysis of Distal Pancreatectomy for Adenocarcinoma: Is Laparoscopic Resection Appropriate?显示文摘 | David A. Kooby William G. Hawkins C. Max Schmidt Sharon M. Weber David J. Bentrem Theresa W. Gillespie Johnita Byrd Sellers Nipun B. Merchant Charles R. Scoggins Robert C.G. Martin Hong Jin Kim Syed Ahmad Clifford S. Cho Alexander A. Parikh Carrie K. Chu | 2010 | Journal of the American College of Surgeons2010，，5： | 2 |
| 9 | Clinical laboratory and imaging evidence for effectiveness of agarose-agarose macrobeads containing stem-like cells derived from a mouse renal adenocarcinoma cell population (RMBs) in treatment-resistant, advanced metastatic colorectal cancer:Evaluation of显示文摘Objective: The complexity, heterogeneity and capacity of malignant neoplastic cells and tumors for rapid change and evolution suggest that living-cell-based biological-systems approaches to cancer treatment are merited. Testing this hypothesis, the tumor marker, metabolic activity, and overall survival(OS) responses, to the use of one such system, implantable macrobeads [RENCA macrobeads(RMBs)], in phase I and IIa clinical trials in advanced,treatment-resistant metastatic colorectal cancer(m CRC) are described here.Methods: Forty-eight m CRC patients(30 females; 18 males), who had failed all available, approved treatments,underwent RMB implantation(8 RMB/kg body weight) up to 4 times in phase I and phase IIa open-label trials.Physicals, labs [tumor and inflammation markers, lactate dehydrogenase(LDH)] and positron emission tomography-computed tomography(PET-CT) imaging to measure number/volume and metabolic activity of the tumors were performed pre-and 3-month-post-implantation to evaluate safety and initial efficacy(as defined by biological responses). PET-CT maximum standard uptake value(SUVmax)(baseline and d 90; SUVmax ≥2.5), LDH,and carcinoembryonic antigen(CEA) and/or cancer antigen 19-9(CA 19-9) response(baseline, d 30 and/or d 60)were assessed and compared to OS.Results: Responses after implantation were characterized by an at least 20% decrease in CEA and/or CA 19-9 in75% of patients. Fluorodeoxyglucose(FDG)-positive lesions(phase I, 39; 2 a, 82) were detected in 37/48 evaluable patients, with 35% stable volume and stable or decreased SUV(10) plus four with necrosis; 10, increased tumor volume, SUV. LDH levels remained stable and low in Responders(R)(d 0–60, 290.4–333.9), but increased steadily in Non-responders(NR)(d 0–60, 382.8–1,278.5)(d 60, P=0.050). Responders to RMBs, indicated by the changes in the above markers, correlated with OS(R mean OS=10.76 months; NR mean OS=4.9 months; P=0.0006).Conclusions: The correlations of the tumor marker, tumor volume and SUV changes on PET-CT, and LDH levels themselves, and with OS, support the concept of a biological response to RMB implantation and the validity of the biological-systems approach to m CRC. A phase III clinical trial is planned. | Barry H.Smith Lawrence S.Gazda Thomas J.Fahey Angelica Nazarian Melissa A.Laramore Prithy Martis Zoe P.Andrada Joanne Thomas Tapan Parikh Sudipta Sureshbabu Nathaniel Berman Allyson J.Ocean Richard D.Hall David J.Wolf | 2018 | Chinese Journal of Cancer Research2018，30，1： | 2 |
| 10 | CD5 expression promotes IL-10 production through activation of the MAPK/Erk pathway and upregulation of TRPC1 channels in B lymphocytes显示文摘CD5 is constitutively expressed on T cells and a subset of mature normal and leukemic B cells in patients with chronic lymphocytic leukemia(CLL).Important functional properties are associated with CD5 expression in B cells,including signal transducer and activator of transcription 3 activation,IL-10 production and the promotion of B-lymphocyte survival and transformation.However,the pathway(s)by which CD5 influences the biology of B cells and its dependence on B-cell receptor(BCR)co-signaling remain unknown.In this study,we show that CD5 expression activates a number of important signaling pathways,including Erk1/2,leading to IL-10 production through a novel pathway independent of BCR engagement.This pathway is dependent on extracellular calcium(Ca2+)entry facilitated by upregulation of the transient receptor potential channel 1(TRPC1)protein.We also show that Erk1/2 activation in a subgroup of CLL patients is associated with TRPC1 overexpression.In this subgroup of CLL patients,small inhibitory RNA(siRNA)for CD5 reduces TRPC1 expression.Furthermore,siRNAs for CD5 or for TRPC1 inhibit IL-10 production.These findings provide new insights into the role of CD5 in B-cell biology in health and disease and could pave the way for new treatment strategies for patients with B-CLL. | Soizic Garaud Taher E Taher Marjolaine Debant Miguel Burgos Sarra Melayah Christian Berthou Kaushal Parikh Jacques-Olivier Pers Damien Luque-Paz Gilles Chiocchia Maikel Peppelenbosch David A Isenberg Pierre Youinou Olivier Mignen Yves Renaudineau Rizgar A Mageed | 2018 | Cellular & Molecular Immunology2018，15，2： | 2 |
| 11 | Indigenous plant medicines for health care:treatment of Diabetes mellitus and hyperlipidemia显示文摘Medicinal plants have played an important role in treating and preventing a variety of diseases throughout the world. Metabolic syndrome had become a global epidemic, defined as a cluster of three of five criteria: insulin resistance and glucose intolerance, abdominal obesity, hypertension, low high-density cholesterol, and hypertriglyceridemia. The current review focuses on Indian medicinal plant drugs and plants used in the treatment of diabetes and hyperlipidemia. Though there are various approaches to reduce the ill-effects of diabetes and hyperlipidemia and its secondary complications, plant-based drugs are preferred due to lesser side effects and low cost. The current review focuses on twenty-three medicinal plants used in the treatment of Diabetes mellitus and nine medicinal plants used in the treatment of hyperlipidemia. The wealth of knowledge on medicinal plants points to a great potential for research and the discovery of new drugs to fight diseases, including diabetes and hyperlipidemia. | Nisha H. Parikh Palak K. Parikh Charmy Kothari | 2014 | Chinese Journal of Natural Medicines2014，12，5： | 2 |
| 12 | Liver regeneration after liver resection: Clinical aspects and correlation with infective complications显示文摘AIM:To investigate whether early liver regeneration after resection in patients with hepatic tumors might be influenced by post-operative infective complications.METHODS:A retrospective analysis of 27 liver resections for tumors performed in a single referral center from November 2004 to January 2010.Regeneration was evaluated by multidetector computed tomographyat a mean follow-up of 43.85 d.The Clavien-Dindo classification was used to evaluate postoperative events in the first 6 mo after transplantation,and Centers for Disease Control and Prevention definitions were used for healthcare associated infections data.Generalized linear regression models with Gaussian family distribution and log link function were used to reveal the principal promoters of early liver regeneration.RESULTS:Ten of the 27 patients(37%)underwent chemotherapy prior to surgery,with a statistically significant prevalence of patients with metastasis(P=0.007).Eight patients(30%)underwent embolization,3 with primary tumors,and 5 with secondary tumors.Twenty patients(74%)experienced complications,with 12(60%)experiencing Clavien-Dindo Grade 3a to 5 complications.Regeneration≥100%occurred in 10(37%)patients.The predictors were smaller future remnant liver volume(-0.002;P<0.001),and a greater spleen volume/future remnant liver volume ratio(0.499;P=0.01).Patients with a resection of≥5 Couinaud segments experienced greater early regeneration(P=0.04).Nine patients experienced surgical site infections,and in 7 cases Clavien-Dindo Grade 3a to 4 complications were detected(P=0.016).There were no significant differences between patients with primary or secondary tumors,and either onset or infections or severity of surgical complications.CONCLUSION:Regardless of the onset of infective complications,future remnant liver and spleen volumes may be reliable predictors of early liver regeneration after hepatic resection on an otherwise healthy liver. | Duilio Pagano Marco Spada Vishal Parikh Fabio Tuzzolino Davide Cintorino Luigi Maruzzelli Giovanni Vizzini Angelo Luca Alessandra Mularoni Paolo Grossi Bruno Gridelli Salvatore Gruttadauria | 2014 | World Journal of Gastroenterology2014，20，22： | 2 |
| 13 | Management of the primary tumor in patients with metastatic pancreatic neuroendocrine tumor: a contemporary single-institution review显示文摘 | Matias Bruzoni Purvi Parikh Rolando Celis Chandrakanth Are Quan P. Ly Jane L. Meza Aaron R. Sasson | 2009 | The American Journal of Surgery2009，，3： | 2 |
| 14 | Total laparoscopic removal of accessory gallbladder:A case report and review of literature显示文摘Accessory gallbladder is a rare congenital anomaly occurring in 1 in 4000 births, that is not associated with any specific symptoms. Usually this cannot be diagnosed on ultrasonography and hence they are usually not diagnosed preoperatively. Removal of the accessory gallbladder is necessary to avoid recurrence of symptoms. H-type accessory gallbladder is a rare anomaly. Once identified intra-operatively during laparoscopic cholecystectomy, the surgery is usually converted to open. By using the main gallbladder for liver traction and doing a dome down technique for the accessory gallbladder, we were able to perform the double cholecystectomy with intra-operative cholangiogram laparoscopically. Laparoscopic cholecystectomy was performed in 27-year-old male for biliary colic. Prior imaging with computer tomography-scan and ultrasound did not show a duplicated gallbladder. Intraoperatively after ligation of cystic artery and duct an additional structure was seen on its medial aspect. Intraoperative cholangiogram confirmed the patency of intra-hepatic and extra-hepatic biliary ducts. Subsequent dissection around this structure revealed a second gallbladder with cystic duct(H-type). Pathological analysis confirmed the presence of two gallbladders with features of chronic cholecystitis. It is important to use cholangiogram to identify structural anomalies and avoid complications. | Yaniv Cozacov Gokulakkrishna Subhas Michael Jacobs Janak Parikh | 2015 | World Journal of Gastrointestinal Surgery2015，7，12： | 2 |
| 15 | Endoscopic Ultrasound and Computed Tomography Predictors of Pancreatic Cancer Resectability显示文摘 | Philip Q. Bao J. Chad Johnson Elizabeth H. Lindsey David A. Schwartz Ron C. Arildsen Ewa Grzeszczak Alexander A. Parikh Nipun B. Merchant | 2008 | Journal of Gastrointestinal Surgery2008，，1： | 2 |
| 16 | Integrating demand side options in electric utility planning: a multi-objective approach显示文摘 | Chattopadhyay D Banerjee R Parikh J | 1995 | IEEE Trans on Power Systems1995，10，2： | 2 |
| 17 | Solid-phase sequence scanning for drug resistance detection in tuberculosis 显示文摘 | Head S R Parikh K Rogers Y H | 1999 | Mol Cellular Probes1999，13，2： | 2 |
| 18 | Intermittent gastric outlet obstruction caused by a prolapsing antral gastric polyp显示文摘Most gastric polyps have an asymptomatic presentation and are an incidental finding on upper endoscopy. Symptomatic presentations can range from an ulcerated polyp leading to anemia and occult bleed to complete gastric outlet obstruction. We report a case of an 89-year-old woman who presented with postprandial nausea and early satiety. Her upper endoscopy revealed a 2 cm pedunculated hyperplastic polyp arising from the antrum of the stomach which was seen prolapsing into the pylorus causing intermittent gastric outlet obstruction. In the present report, we statistically analyzed 39 prolapsing gastric polyps previously reported in the English literature and demonstrate the current utility of monopolar snare polypectomy in establishing a histological diagnosis while offering simultaneous treatment. Additionally, we review the literature for the management of all hyperplastic gastric polyps in relation to advancements in digestive endoscopy. | Mehul Parikh Brian Kelley Gabriel Rendon Bincy Abraham | 2010 | World Journal of Gastrointestinal Oncology2010，2，5： | 2 |
| 19 | Is myopia a protective factor against central serous chorioretinopathy?显示文摘AIM: To evaluate if any association exists between central serous chorioretinopathy(CSCR) and the refractive status of the eye.· METHODS: This retrospective, institutional, case control study included 499 patients, wherein 262 patients diagnosed as acute CSCR, were compared with an age and gender matched control group of 237 patients. All patients were evaluated with a detailed systemic and ocular history, objective and subjective refractions for both eyes and complete ocular examination by a retina specialist, at all visits. Optical coherence tomography confirmed the diagnosis of CSCR.·RESULTS: The mean age was found to be 40±7y in the study group(Group 1) compared to 38±10y in the control group(Group 2). Most common refractive status in the study group, was emmetropia seen in 191 patients(72.9%), followed by hypermetropia seen in 47 patients(17.9%) and astigmatism seen in 21 patients(8.0%). Only3 subjects(1.1%) had myopia, which was less than or equal to 1.0 D, compared to 70 subjects(29.5%) in the control group, suggesting a statistically significant lower incidence of CSCR among the myopic patients(P <0.0001). With respect to the systemic factors, 26(9.9%)patients were using systemic steroids in the study group(Group 1) compared to none in the control group(Group 2)suggesting a statistically significant association of CSCR with systemic steroid use(P <0.05). No other significant systemic risk factors were noted.· CONCLUSION: Though CSCR is a multifactorial disease, myopia serves as a protective factor for CSCR.Thus, myopic eyes are less likely to develop CSCR.Since both retinal pigment epithelium(RPE) and choriocapillaris are postulated in the pathogenesis of CSCR, chorio-retinal thinning and atrophy seen in myopic eyes are less likely to cause CSCR. | George J.Manayath Saurabh Arora Hardik Parikh Parag K.Shah Sarvesh Tiwari Venkatapathy Narendran | 2016 | International Journal of Ophthalmology(English edition)2016，9，2： | 2 |
| 20 | Vedolizumab for the treatment of active ulcerative colitis: A randomized controlled phase 2 dose‐ranging study显示文摘 | Asit Parikh Timothy Leach Tim Wyant Catherine Scholz Serap Sankoh Diane R. Mould Terry Ponich Irving Fox Brian G. Feagan | 2011 | Inflamm Bowel Dis2011，，8： | 2 |
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