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201篇 您的检索式:作者名="SIMON RP"
    题名 作者 年代 出处 被引量
1缺血性脑损伤机制的研究进展显示文摘在美国,中风是致死第三大因素,致残的首要因素。中风引起的脑损伤由有着复杂相互作用的多个通路引起,包括兴奋性神经毒性,酸中毒,电解质失衡,围梗死去极化,氧化和硝化应激,炎症反应和细胞凋亡。对于中风而言,现在有效的治疗途径很少。那么,探索新的治疗方法就需要对各种脑缺血损伤机制的全面了解。本文讨论基本的中风的病理生理过程,揭示治疗干预可靶向复杂通路。Doyle KP Simon RP Stenztl-Peore MP 王竞 杜俊蓉 2008国际药学研究杂志2008,35,4:14
2Prior ischemic stress protects against experimental stroke 显示文摘Simon RP Niiro M Gwinn R 1993Neurosci Lett1993,163,2:1
3Ca^2+-permeable acid-sensing ion channels and ischemic brain injury显示文摘Xiong ZG Chu XP Simon RP 2006J Membr Biol2006,209,1:1
4Acid sensing ion channels novel therapeutic targets for ischemic brain injury显示文摘Xiong ZG Chu XP Simon RP 2007Front Biosci2007,,12:1
5Noninvasive prediction of fibrosis in patients with chronic hepatitis C 显示文摘Thabut D Simon M Myers RP 2003Hepatology2003,37,2:1
6Involvement of caspase-3-like protease in the mechanism of cell death following focally evoked limbic seizures显示文摘Henshall DC Chen J Simon RP 2000Neurochem2000,74,3:1
7Involvement of caspase - 3 - like protease in the mechanism of cell death following focally evoked limbic sei2 zures 显示文摘Henshall DC Chen J Simon RP 2000J Neurochem2000,74,3:1
8Status epilepticus:Causes,clinical features and consequences in 98 patients显示文摘Aminoff MJ Simon RP 1980Am J Med1980,69,:1
9Subcellular distribution of Bel-2 family proteins and 14-3-3 within the hippocampus during seizure-induced neuronaldeath in the rat显示文摘Schindler CK Shinoda S Simon RP 2004Neurosci Lett2004,356,3:1
10Involvement of caspase-3-1ike protease in the mechenism of cell death folowing focaly evoked limbic seizure 显示文摘Henshall DC Chen J Simon RP 2000J Neurochem2000,74,:1
11A potential role for excitotoxins in the pathophysiology of spinal cord injury 显示文摘Faden AI Simon RP 1998Ann Neurol1998,23,6:1
12Cyclic AMP response element binding protein (CREB) and CREB binding protein (CBP) in global cerebral ischemia显示文摘Jin K Mao XO Simon RP 2001J Mol Neurosci2001,16,1:1
13Hypoxia versus ischemia显示文摘Simon RP 1999Neurology1999,52,:1
14Spatio-temporal profile of DNA fragmentation and its relationship to patterns of epileptiform activity following focally evoked limbic seizures显示文摘Henshall DC Sinclair J Simon RP 2000Brain Res2000,858,2:1
15Acid sensing ion channels novel therapeutic targets for isehemic brain injury 显示文摘Xiong ZG Chu XP Simon RP 2007Front Biosci2007,1,12:1
16The role of glutamate in central nervous system health and disease-a review显示文摘Simon RP 2007The Veterinary Journal2007,173,:1
17Epilepsy and apoptosis path ways显示文摘Henshall DC Simon RP 2005J Cereb Blood Flow Metab2005,25,12:1
18Subcellular distribution of bel-2 family proteins and 14-3-3 within the hippoeampus during seizure induced neural death in the rat 显示文摘Schindler CK Shinoda S Simon RP 2004Neurnsei Lett2004,356,3:1
19Ethanol and the nervous system显示文摘Charness ME Simon RP Greenberg DA 1989N Engl J Med1989,321,7:1
20Involvement of caspase-3-like protease in the mechanism of cell death following focally evoked limbic seizures显示文摘Henshall DC Chen J Simon RP 2000J Neurochem2000,74,3:1
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