|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | The MicroRNA-21/PTEN Pathway Regulates the Sensitivity of HER2-Positive Gastric Cancer Cells to Trastuzumab显示文摘 | Kojiro Eto Masaaki Iwatsuki Masayuki Watanabe Satoshi Ida Takatsugu Ishimoto Shiro Iwagami Yoshifumi Baba Yasuo Sakamoto Yuji Miyamoto Naoya Yoshida Hideo Baba | 2014 | Annals of Surgical Oncology2014，，1： | 2 |
| 2 | Generation of Pluripotent Stem Cells from Neonatal Mouse Testis显示文摘 | Mito Kanatsu-Shinohara Kimiko Inoue Jiyoung Lee Momoko Yoshimoto Narumi Ogonuki Hiromi Miki Shiro Baba Takeo Kato Yasuhiro Kazuki Shinya Toyokuni Megumi Toyoshima Ohtsura Niwa Mitsuo Oshimura Toshio Heike Tatsutoshi Nakahata Fumitoshi Ishino Atsuo Ogura T | 2004 | Cell2004，，7： | 2 |
| 3 | Cytopathic effects and local immune responses in repeated neoadjuvant HSV-tk+ ganciclovir gene therapy for prostate cancer显示文摘Objective:Cytopathic effects and local immune response were analyzed histologically in prostatic cancer(PCa)with in situ herpes simplex virus-thymidine kinase(HSV-tk)/ganciclovir(GCV)gene therapy(GT).Methods:Four high-risk PCa patients who received HSV-tk/GCV GT were investigated.After two cycles of intraprostatic injection of HSV-tk and administration of GCV,radical prostatectomy was performed.Formalin-fixed,paraffin-embedded sections were evaluated using immunohistochemistry.PCa with hormone therapy(HT,n=3)or without neoadjuvant therapy(NT,n=4)that were equivalent in terms of risk were also examined as reference.Immunoreactively-positive cells were counted in at least three areas in cancer tissue.Labeling indices(LI)were calculated as percentage values.Results:ssDNA LI in GT increased,indicating apoptosis,as well as tumor-infiltrating lymphocytes and CD68-positive macrophages,compared with their biopsies.GT cases showed significantly higher numbers of single-stranded DNA(ssDNA)LI,CD4/CD8-positive T cells and CD68-positive macrophages including M1/M2 macrophages than HT or NT cases.However,there was no significant difference in CD20-positive B cells among the types of case.There were strong correlations between CD8+T cells and CD68+macrophages(ρ=0.656,p<0.0001)as well as CD4+T cells and CD20+B cells(ρ=0.644,p<0.0001)in PCa with GT.Conclusions:Enhanced cytopathic effect and local immune response might be indicated in PCa patients with HSV-tk/GCV gene therapy. | Nobuyuki Yanagisawa Takefumi Satoh Ken-ichi Tabata Hideyasu Tsumura Yasutomo Nasu Masami Watanabe Timothy C.Thompson Isao Okayasu Yoshiki Murakumo Shiro Baba Masatsugu Iwamura | 2021 | Asian Journal of Urology2021，8，3： | 1 |
| 4 | Immunoassay for acetamiprid detection: application to residue analysis and comparison with liquid chromatography显示文摘 | Eiki Watanabe Shiro Miyake Koji Baba Heesoo Eun Shozo Endo | 2006 | Analytical and Bioanalytical Chemistry2006，，5： | 1 |
| 5 | Analytical evaluation of enzymelinked immunosorbent assay for nennicotinoid dinotefuran for potential application to quick and simple screening method in rice samples显示文摘 | Eiki Watanabe KOJl Baba SHIRO miyake | 2011 | Talanta2011，84，4： | 1 |
| 6 | Primary Malignant Melanoma of the Esophagus With Extensive Intraepithelial Extension显示文摘 | Kyoko Inadomi Takatsugu Ishimoto Masayuki Watanabe Masaaki Iwatsuki Kota Arima Satoshi Ida Yohei Nagai Shiro Iwagami Yoshifumi Baba Yasuo Sakamoto Yuji Miyamoto Yumi Honda Ken-ichi Iyama Hideo Baba | 2012 | The Annals of Thoracic Surgery2012，，6： | 1 |
| 7 | LINE-1 hypomethylation in gastric cancer, detected by bisulfite pyrosequencing, is associated with poor prognosis显示文摘 | Hironobu Shigaki Yoshifumi Baba Masayuki Watanabe Asuka Murata Shiro Iwagami Keisuke Miyake Takatsugu Ishimoto Masaaki Iwatsuki Hideo Baba | 2013 | Gastric Cancer2013，，4： | 1 |
| 8 | Prognostic Nutritional Index Predicts Outcomes of Gastrectomy in the Elderly显示文摘 | Masayuki Watanabe Masaaki Iwatsuki Shiro Iwagami Takatsugu Ishimoto Yoshifumi Baba Hideo Baba | 2012 | World Journal of Surgery2012，，7： | 1 |
| 9 | Negative lymph-node count is associated with survival in patients with resected esophageal squamous cell carcinoma显示文摘 | Yoshifumi Baba Masayuki Watanabe Hironobu Shigaki Shiro Iwagami Takatsugu Ishimoto Masaaki Iwatsuki Hideo Baba | 2012 | Surgery2012，，： | 1 |
| 10 | Immunoassay for acetamiprid detection: application to residue analysis and comparison with liquid chromatography 显示文摘 | Eiki Watanabe Shiro Miyake Koji Baba | 2006 | Analytical and Bioanalytical Chemistry2006，386，5： | 1 |
| 11 | p53 immunohistochemical expression and patient prognosis in esophageal squamous cell carcinoma显示文摘 | Asuka Murata Yoshifumi Baba Masayuki Watanabe Hironobu Shigaki Keisuke Miyake Ryuichi Karashima Yu Imamura Satoshi Ida Takatsugu Ishimoto Shiro Iwagami Yasuo Sakamoto Yuji Miyamoto Naoya Yoshida Hideo Baba | 2013 | Medical Oncology2013，，4： | 1 |
| 12 | Generation of Pluripotent Stem Cells from Neonatal Mouse Testis显示文摘 | Mito Kanatsu-Shinohara Kimiko Inoue Jiyoung Lee Momoko Yoshimoto Narumi Ogonuki Hiromi Miki Shiro Baba Takeo Kato Yasuhiro Kazuki Shinya Toyokuni Megumi Toyoshima Ohtsura Niwa Mitsuo Oshimura Toshio Heike Tatsutoshi Nakahata Fumitoshi Ishino Atsuo Ogura T | 2004 | Cell2004，，7： | 1 |
| 13 | An application of tetra zolim(MTT) colorimetric assay for the screening of anti - herpes simplex virus compounds显示文摘 | Histoshi Takeuchi Masanori Baba Shiro Shigeta | 1991 | Viral Methods1991，33，2： | 1 |
| 14 | LINE-1 Hypomethylation Is Associated With a Poor Prognosis Among Patients With Curatively Resected Esophageal Squamous Cell Carcinoma显示文摘 | Shiro Iwagami Yoshifumi Baba Masayuki Watanabe Hironobu Shigaki Keisuke Miyake Takatsugu Ishimoto Masaaki Iwatsuki Kentaro Sakamaki Yasuo Ohashi Hideo Baba | 2013 | Annals of Surgery2013，，3： | 1 |
| 15 | p53 immunohistochemical expression and patient prognosis in esophageal squamous cell carcinoma显示文摘 | Asuka Murata Yoshifumi Baba Masayuki Watanabe Hironobu Shigaki Keisuke Miyake Ryuichi Karashima Yu Imamura Satoshi Ida Takatsugu Ishimoto Shiro Iwagami Yasuo Sakamoto Yuji Miyamoto Naoya Yoshida Hideo Baba | 2013 | Medical Oncology2013，，4： | 1 |
| 16 | Difference in rectal dosimetry between pre-plan and post-implant analysis in transperineal interstitial brachytherapy for prostate cancer显示文摘 | Hiromichi Ishiyama Masashi Kitano Takefumi Satoh Yuzuru Niibe Mineko Uemae Tetsuo Fujita Shiro Baba Kazushige Hayakawa | 2006 | Radiotherapy and Oncology2006，，： | 1 |
| 17 | LINE-1 Hypomethylation Is Associated With a Poor Prognosis Among Patients With Curatively Resected Esophageal Squamous Cell Carcinoma显示文摘 | Shiro Iwagami Yoshifumi Baba Masayuki Watanabe Hironobu Shigaki Keisuke Miyake Takatsugu Ishimoto Masaaki Iwatsuki Kentaro Sakamaki Yasuo Ohashi Hideo Baba | 2013 | Annals of Surgery2013，，3： | 1 |
| 18 | Quality of life after brachytherpay or radical prostatectomy for localized prostate cancer显示文摘 | Shunichi Namiki Takefumi Satoh Shiro Baba | 2006 | Urology2006，68，6： | 1 |
| 19 | Recovery of serum testosterone following neoadjuvant and adjuvant androgen deprivation therapy in men treated with prostate brachytherapy显示文摘AIM: To investigate the time course of testosterone(T) recovery after cessation of androgen deprivation therapy(ADT) in patients treated with brachytherapy. METHODS: One-hundred and seventy-four patients treated between June 1999 and February 2009 were studied. Patients were divided into a short-term usage group(≤ 12 mo, n = 91) and a long-term usage group(≥ 36 mo, n = 83) according to the duration of gonadotropin-releasing hormone agonist therapy. Median follow-up was 29 mo in the short-term group and was 60 mo in the long-term group.RESULTS: Cumulative incidence rates of T recovery to normal and supracastrate levels at 24 mo after cessationwere 28.8% and 74.6%, respectively, in the long-term usage group, whereas these values were 96.4% and 98.8% in the short-term usage group. T recovery to normal and supracastrate levels occurred significantly more rapidly in the short-term than in the long-term usage group(P < 0.001 and P < 0.001, respectively). Five years after cessation, 22.6% of patients maintained a castrate T level in the long-term usage group. On multivariate analysis, lower T levels(< 10 ng/d L) at cessation of ADT was significantly associated with prolonged T recovery to supracastrate levels in the longterm usage group(P = 0.002). CONCLUSION: Lower T levels at cessation of ADT were associated with prolonged T recovery in the longterm usage group. Five years after cessation of longterm ADT, approximately one-fifth of patients still had castrate T levels. When determining the therapeutic effect, especially biochemical control, we should consider this delay in T recovery. | Hideyasu Tsumura Takefumi Satoh Hiromichi Ishiyama Shuhei Hirano Kenichi Tabata Shinji Kurosaka Kazumasa Matsumoto Tetsuo Fujita Masashi Kitano Shiro Baba Kazushige Hayakawa Masatsugu Iwamura | 2015 | World Journal of Radiology2015，7，12： | 0 |
| 20 | Contracted interlayer distance in graphene/sapphire heterostructure显示文摘绝缘体上的 graphene 的直接生长被期望在性能产出重要改进基于 graphene 电子并且 spintronic 设备。在这研究,我们成功地揭示原子安排和单个层的 graphene 和 -Al 2 O < 潜水艇 class= “ a-plus-plus ” > 3 (0001) 。-Al 2 O < 潜水艇 class= “ a-plus-plus ” > 3 (0001) 揭示了 apparentcontradiction。在里面飞机分析证明单个层的 graphene 不以一种单人赛水晶的取向附生的方式,但是相当在多晶的形式成长,与二强烈显著的比较喜欢的取向。这建议相对弱的界面的相互作用是起作用的。然而,我们表明那在 graphene 和 -Al 2 O <潜水艇class=“ a-plus-plus ”> 3 (0001)存在,是由在 graphene 和 -Al 2 O <潜水艇class=“ a-plus-plus ”> 3 (0001)表面。界面的相互作用被显示被涉及 graphene 系统和 -Al 2 O < 潜水艇 class= “ a-plus-plus ” > 3 (0001), 而非货车 der Waals 相互作用。做的如此的特征原因 graphene 洞并且使 graphene 能在 -Al 2 O < 潜水艇 class= “ a-plus-plus ” > 有尽管有强壮的界面的相互作用的一个仅仅小精力障碍的 3 (0001) 表面。 | Shiro Entani Liubov Yu. Antipina Pavel V. Avramov Manabu Ohtomo Yoshihiro Matsumoto Norie Hirao Iwao Shimoyama Hiroshi Naramoto Yuji Baba Pavel B. Sorokin Seiji Sakai | 2015 | Nano Research2015，8，5： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员