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| 1 | Characteristics of postintensive care syndrome in survivors of pediatric critical illness: A systematic review显示文摘AIM To synthesize the available evidence focusing on morbidities in pediatric survivors of critical illness that fall within the defined construct of postintensive care syndrome(PICS) in adults, including physical, neurocognitive and psychological morbidities.METHODS A comprehensive search was conducted in MEDLINE, EMBASE, the Cochrane Library, Psyc INFO, and CINAHL using controlled vocabulary and key word terms to identify studies reporting characteristics of PICS in pediatric intensive care unit(PICU) patients. Two reviewers independently screened all titles and abstracts and performed data extraction. From the 3176 articles identified in the search, 252 abstracts were identified for full text review and nineteen were identified for inclusion in the review. All studies reporting characteristics of PICS in PICU patients were included in the final synthesis. RESULTS Nineteen studies meeting inclusion criteria published between 1995 and 2016 were identified and categorized into studies reporting morbidities in each of three categories-physical, neurocognitive and psychological. The majority of included articles reported prospective cohort studies, and there was significant variability in the outcome measures utilized. A synthesis of the studies indicate that morbidities encompassing PICS are well-described in children who have survived critical illness, often resolving over time. Risk factors for development of these morbidities include younger age, lower socioeconomic status, increased number of invasive procedures or interventions, type of illness, and increased benzodiazepine andnarcotic administration.CONCLUSION PICS-related morbidities impact a significant proportion of children discharged from PICUs. In order to further define PICS in children, more research is needed using standardized tools to better understand the scope and natural history of morbidities after hospital discharge. Improving our understanding of physical, neurocognitive, and psychological morbidities after critical illness in the pediatric population is imperative for designing interventions to improve long-term outcomes in PICU patients. | Elizabeth A Herrup Beth Wieczorek Sapna R Kudchadkar | 2017 | World Journal of Critical Care Medicine2017，6，2： | 7 |
| 2 | Analyses of Lattice Traffic Flow Model on a Gradient Highway显示文摘The optimal current difference lattice hydrodynamic model is extended to investigate the traffic flow dynamics on a unidirectional single lane gradient highway. The effect of slope on uphill/downhill highway is examined through linear stability analysis and shown that the slope significantly affects the stability region on the phase diagram.Using nonlinear stability analysis, the Burgers, Korteweg-deVries(KdV) and modified Korteweg-deVries(mKdV) equations are derived in stable, metastable and unstable region, respectively. The effect of reaction coefficient is examined and concluded that it plays an important role in suppressing the traffic jams on a gradient highway. The theoretical findings have been verified through numerical simulation which confirm that the slope on a gradient highway significantly influence the traffic dynamics and traffic jam can be suppressed efficiently by considering the optimal current difference effect in the new lattice model. | Arvind Kumar Gupta Sapna Sharma Poonam Redhu | 2014 | Communications in Theoretical Physics2014，61，9： | 5 |
| 3 | Secondary pancreatic involvement by a diffuse large B-cell lymphoma presenting as acute pancreatitis显示文摘Diffuse large B-cell lymphoma is the most common type of non-Hodgkin's lymphoma. More than 50% of patients have some site of extra-nodal involvement at diagnosis, including the gastrointestinal tract and bone marrow. However, a diffuse large B-cell lymphoma presenting as acute pancreatitis is rare. A 57-year-old female presented with abdominal pain and matted lymph nodes in her axilla. She was admitted with a diagnosis of acute pancreatitis. Abdominal computed tomography (CT) scan showed diffusely enlarged pancreas due to infiltrative neoplasm and peripancreatic lymphadenopathy. Biopsy of the axillary mass revealed a large B-cell lymphoma. The patient was classified as stage Ⅳ, based on the Ann Arbor Classification, and as having a high-risk lymphoma, based on the International Prognostic Index. She was started on chemotherapy with CHOP (cyclophosphamide, doxorubicin, vincristine and prednisone). Within a week after chemotherapy, the patient’s abdominal pain resolved. Follow-up CT scan of the abdomen revealed a marked decrease in the size of the pancreas and peripancreatic lymphadenopathy. A literature search revealed only seven cases of primary involvement of the pancreas in B-cell lymphoma presenting as acute pancreatitis. However, only one case of secondary pancreatic involvement by B-cell lymphoma presenting as acute pancreatitis has been published. Our case appears to be the second report of such a manifestation. Both cases responded well to chemotherapy. | M Wasif Saif Sapna Khubchandani Marek Walczak | 2007 | World Journal of Gastroenterology2007，13，36： | 4 |
| 4 | Inhibiting Mitochondrial Fission Protects the Heart Against Ischemia/Reperfusion Injury显示文摘 | Sang-Bing Ong Sapna Subrayan Shiang Y. Lim Derek M. Yellon Sean M. Davidson Derek J. Hausenloy | 2010 | Circulation2010，，18： | 3 |
| 5 | Nonlinear analysis of traffic jams in an anisotropic continuum model显示文摘This paper presents our study of the nonlinear stability of a new anisotropic continuum traffic flow model in which the dimensionless parameter or anisotropic factor controls the non-isotropic character and diffusive influence.In order to establish traffic flow stability criterion or to know the critical parameters that lead,on one hand,to a stable response to perturbations or disturbances or,on the other hand,to an unstable response and therefore to a possible congestion,a nonlinear stability criterion is derived by using a wavefront expansion technique.The stability criterion is illustrated by numerical results using the finite difference method for two different values of anisotropic parameter.It is also been observed that the newly derived stability results are consistent with previously reported results obtained using approximate linearisation methods.Moreover,the stability criterion derived in this paper can provide more refined information from the perspective of the capability to reproduce nonlinear traffic flow behaviors observed in real traffic than previously established methodologies. | Arvind Kumar Gupta Sapna Sharma | 2010 | Chinese Physics B2010，19，11： | 3 |
| 6 | Properties of a New Dental Photocurable Resin based on the Expanding Monomer and Threecomponent Photoinitiator System显示文摘The purpose of this study was to use a three-component photoinitiation system comprising 1wt% CQ(camphorquinone), 2wt% DMAEMA(2-(dimethylamino) ethyl meth acrylate) and 2wt% Ph2I+PF6-(diphenyliodonium hexafluorophosphate) to initiate the copolymerization of the matrix resins which combine bisphenol-S-bis(3-methacrylate-2-hydroxy propyl) ether(BisS-GMA) with the expanding monomer unsaturated spiro orthoesters 2-methylene-1,4,6-trispiro[4,4] nonane(MTOSN), for minimizing the volumetric shrinkage that generally occurs during polymerization. It was hypothesized that MTOSN would expand volumetrically during polymerization under the three-component photoinitiator system and further reductions in volumetric shrinkage would be obtained. The performance study which consists of degree of conversion and condition of the ring-opening reactions of MTOSN, volumetric shrinkage and mechanical properties including tensile bond strength, compressive strength and Vicker's hardness were carried out respectively by Fourier transfer infrared, the dilatometer and the universal testing machine. The results supported that the dental composites based on the expanding monomer and three-component photoinitiator system engendered a greater decrease of volumetric shrinkage and better mechanical properties. | 付静 LIU Wenjia LIU Xiaoqing Sapna laxmi tuladhar WAN Qianbing 王航 | 2014 | Journal of Wuhan University of Technology(Materials Science)2014，29，2： | 3 |
| 7 | Mutant TP53 in Duodenal Samples of Pancreatic Juice From Patients With Pancreatic Cancer or High-Grade Dysplasia显示文摘 | Mitsuro Kanda Yoshihiko Sadakari Michael Borges Mark Topazian James Farrell Sapna Syngal Jeffrey Lee Ihab Kamel Anne Marie Lennon Spencer Knight Sho Fujiwara Ralph H. Hruban Marcia Irene Canto Michael Goggins | 2013 | Clinical Gastroenterology and Hepatology2013，，6： | 2 |
| 8 | Frequent Detection of Pancreatic Lesions in Asymptomatic High-Risk Individuals显示文摘 | Marcia Irene Canto Ralph H. Hruban Elliot K. Fishman Ihab R. Kamel Richard Schulick Zhe Zhang Mark Topazian Naoki Takahashi Joel Fletcher Gloria Petersen Alison P. Klein Jennifer Axilbund Constance Griffin Sapna Syngal John R. Saltzman Koenraad J. Mortele | 2012 | Gastroenterology2012，，4： | 2 |
| 9 | Calculation of Risk of Colorectal and Endometrial Cancer Among Patients With Lynch Syndrome显示文摘 | Elena Stoffel Bhramar Mukherjee Victoria M. Raymond Nabihah Tayob Fay Kastrinos Jennifer Sparr Fei Wang Prathap Bandipalliam Sapna Syngal Stephen B. Gruber | 2009 | Gastroenterology2009，，5： | 2 |
| 10 | Precision phenotyping of contrasting potato(Solanum tuberosum L.) varieties in a novel aeroponics system for improving nitrogen use efficiency: In search of key traits and genes显示文摘With increasing population, degrading soil health, limited arable land area, and high cost of nitrogen(N) fertilizers, improving nitrogen use efficiency(NUE) of potato is an inevitable approach to save the environment and achieve sufficient tuber yields with less N fertilizer supply. Recently, we have developed an aeroponics system to study NUE in potato using genomics, physiology, and breeding approaches. This study aims on precision phenotyping of plants of two distinct potato varieties(Kufri Gaurav, N efficient;Kufri Jyoti, N inefficient) in the novel aeroponics system. Plants were grown in aeroponics under controlled conditions with low N(0.75 mmol L^-1NO3^-) and high N(7.5 mmol L^-1NO3^-) levels. Plant biomass, root traits, total chlorophyll content, and plant N were increased with increasing N supply, whereas higher NUE parameters namely NUE, agronomic NUE(Ag NUE), N uptake efficiency(NUp E), harvest index(HI), and N harvest index(NHI) were observed at low N. An NUE efficient cv. Kufri Gaurav showed higher tuber dry weight, fresh tuber yield, tuber number per plant, early start of tuber harvesting, root traits, stolon traits, NUE parameters, and higher amino acid(aspartic acid and asparagine) content at low N supply. Higher expression of nitrate reductase(NR), nitrite reductase(NIR), and asparagine synthetase(AS) genes was observed in the leaf tissues of Kufri Gaurav at high N. Thus, aeroponics-based precision phenotyping enables identification of NUE efficient genotypes based on key traits and genes involved in improving NUE in potato. Further, this study suggests that the potential of aeroponics can be utilized to investigate N biology in potato under different N regimes. | Jagesh K.TIWARI Sapna DEVI Tanuja BUCKSETH Nilofer ALI Rajesh K.SINGH Rasna ZINTA Vijay K.DUA Swarup K.CHAKRABARTI | 2020 | Journal of Integrative Agriculture2020，19，1： | 2 |
| 11 | Analysis of the wave properties of a new two-lane continuum model with the coupling effect显示文摘A multilane extension of the single-lane anisotropic continuum model (GK model) developed by Gupta and Katiyar for traffic flow is discussed with the consideration of the coupling effect between the vehicles of different lanes in the instantaneous traffic situation and the lane-changing effect.The conditions for securing the linear stability of the new model are presented.The shock and the rarefaction waves,the local cluster effect and the phase transition are investigated through simulation experiments with the new model and are found to be consistent with the diverse nonlinear dynamical phenomena observed in a real traffic flow.The analysis also focuses on empirically observed twolane phenomena,such as lane usage inversion and the density dependence of the number of lane changes.It is shown that single-lane dynamics can be extended to multilane cases without changing the basic properties of the single-lane model.The results show that the new multilane model is capable of explaining some particular traffic phenomena and is in accordance with real traffic flow. | Arvind Kumar Gupta Sapna Sharma | 2012 | Chinese Physics B2012，21，1： | 2 |
| 12 | Cyclosporine for Ocular Inflammatory Diseases显示文摘 | R. Oktay Ka?maz John H. Kempen Craig Newcomb Ebenezer Daniel Sapna Gangaputra Robert B. Nussenblatt James T. Rosenbaum Eric B. Suhler Jennifer E. Thorne Douglas A. Jabs Grace A. Levy-Clarke C. Stephen Foster | 2010 | Ophthalmology2010，，3： | 1 |
| 13 | An (s,S) perishable system with arbitrary distributed leadtimes显示文摘 | Kalpakam S Sapna S P | 1996 | Opsearch1996，，33： | 1 |
| 14 | Freeze–dried synthesized bifunctional biopolymer nanocomposite for efficient fluoride removal and antibacterial activity显示文摘Local fluoride contamination and bacterial infections in potable water have dangerous effects on the human body and are today a global concern.In this study,we have synthesized a pH-responsive bifunctional biopolymer nanocomposite(HAZ)of humic acid with incorporating aluminum zirconium bimetallic oxide by deep freeze–drying method.Fast nucleation and interconnection of nanoparticles form a highly porous network because of sublimation of frozen HAZ.This duo nanocomposite has efficiently worked for fluoride removal and showed potent antibacterial activity against the Escherichia coli Gram-negative and Staphylococcus aureus Gram-positive bacteria.The X-ray photoelectron spectroscopy(XPS)analysis demonstrates that the hydroxyl groups act as a pivot in the ion exchange process of adsorption,each element of bimetallic oxide primarily takes part in the adsorption mechanism.The maximum adsorption capacity of the adsorbent was 180.62 mg/g at pH seven.Thermodynamic parameters like Gibbs free energy change(△G0),entropy(△S0),and enthalpy(△H0)indicate that the process was endothermic,feasible,and taken place by a chemisorption mechanism.This is the first novel freeze–dried bifunctional biopolymer nanocomposite composed of humic acid natural polymer incorporated with Al–Zr metal oxide,and it exhibited three times higher adsorption efficacy with excellent antibacterial action at a concentration of 5μg/mL of the nanocomposite. | Sapna Nehra Ankita Dhillon Dinesh Kumar | 2020 | Journal of Environmental Sciences2020，32，8： | 1 |
| 15 | Controlled porosity osmotic pump-based controlled release systems of pseudoephedrine显示文摘 | Sapna N Makhija Pradeep R Vavia | 2003 | Journal of Controlled Release2003，，1： | 1 |
| 16 | Frequent Detection of Pancreatic Lesions in Asymptomatic High-Risk Individuals显示文摘 | Marcia Irene Canto Ralph H. Hruban Elliot K. Fishman Ihab R. Kamel Richard Schulick Zhe Zhang Mark Topazian Naoki Takahashi Joel Fletcher Gloria Petersen Alison P. Klein Jennifer Axilbund Constance Griffin Sapna Syngal John R. Saltzman Koenraad J. Mortele | 2012 | Gastroenterology2012，，4： | 1 |
| 17 | Stability indicating HPTLC method for the simultaneous determination of pseudoephedrine and cetirizine in pharmaceutical formulations显示文摘 | Sapna N Makhija Pradeep R Vavia | 2001 | Journal of Pharmaceutical and Biomedical Analysis2001，25，： | 1 |
| 18 | Genotoxicity of the Herbicide Butachlor in Cultured Human Lymphocytes Mutation Research, Genetic Toxicology 显示文摘 | Sapna S Natarajan P L Govindaswamy S | 1995 | 344 (1 - 2): 63 -671995，344，12： | 1 |
| 19 | A Novel Technique for the Fabrication of Laboratory Scale Model Functionally Graded Materials 显示文摘 | Lambros J Santare M H Li H and Sapna Ⅲ G H | 1999 | Experimental Mechanics1999，39，3： | 1 |
| 20 | CanonicalWnts function as potent regulators of osteogenesis by human mesenc-hymal stem cells显示文摘 | Guizhong Liu Sapna Vijayakumar Luca Grumolato | 2009 | JCB2009，185，： | 1 |
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