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| 1 | Towards Quantitatively Understanding the Complexity of Social-Ecological Systems——From Connection to Consilience显示文摘The complexity of social-ecological systems(SES) is rooted in the outcomes of node activities connected by network topology. Thus far, in network dynamics research, the connectivity degree(CND), indicating how many nodes are connected to a given node, has been the dominant concept. However, connectivity focuses only on network topology, neglecting the crucial relation to node activities, and thereby leaving system outcomes largely unexplained. Inspired by the phenomenon of ‘‘consensus of wills and coordination of activities' ' often observed in disaster risk management, we propose a new concept of network characteristic, the consilience degree(CSD),aiming to measure the way in which network topology and node activities together contribute to system outcomes. The CSD captures the fact that nodes may assume different states that make their activities more or less compatible.Connecting two nodes with in/compatible states will lead to outcomes that are un/desirable from the perspective of the SES in question. We mathematically prove that the CSD is a generalized CND, and the CND is a special case of CSD. As a general, fundamental concept, the CSD can facilitate the development of a new framework of network properties, models, and theories that allows us to understand patterns of network behavior that cannot be explained in terms of connectivity alone. We further demonstrate that a co-evolutionary mechanism can naturally improve the CSD. Given the generality of co-evolution in SES, we argue that the CSD is an inherent attribute rather than an artificial concept, which underpins the fundamental importance of the CSD to the study of SES. | Xiao-Bing Hu Peijun Shi Ming Wang Tao Ye Mark S.Leeson Sander E.van der Leeuw Jianguo Wu Ortwin Renn Carlo Jaeger | 2017 | International Journal of Disaster Risk Science2017，8，4： | 4 |
| 2 | Gastric sarcoidosis mimicking irritable bowel syndrome-Cause not association?显示文摘肉状瘤是可以在身体影响任何机关的未知原因论的系统病。胃肠道仅仅很少然而在肝外面被影响。症状可能是非特定的。急躁的肠症候群(IBS ) 是普通诊断。IBS 的识别被罗马 II 标准的使用帮助 - 当器质性病不在时。我们与胃的肉状瘤描述一个病人的第一个盒子与 IBS 介绍了症状,但是随后对抑制免疫力的治疗作出回应。 | John Samuel Leeds Mark Edward McAlindon Eleanor Lorenz Asha Kumari Dube David Surendran Sanders | 2006 | World Journal of Gastroenterology2006，12，29： | 3 |
| 3 | Efficient isolation of major procyanidin A-type dimers from peanut skins and B- type dimers from grape seeds 显示文摘 | Appeldoorn Maaike M Sanders Mark Vincken Jean- Paul et a/ | 2009 | Food Chemistry2009，117，4： | 1 |
| 4 | Primary periosteal lymphoma: an unusual presentation of non-Hodgkin’s lymphoma with radiographic, MR imaging, and pathologic correlation显示文摘 | Scot E. Campbell Timothy W. Filzen Shane M. Bezzant Douglas P. Beall Mark P. Burton Timothy G. Sanders Theodore W. Parsons | 2003 | Skeletal Radiology2003，，4： | 1 |
| 5 | Prediction of human microR- NA targets 显示文摘 | John B Sander C Marks DS | 2006 | Methods Mol Biol2006，342，： | 1 |
| 6 | Theory of mind-based action in children form the autism spectrum显示文摘 | Sander B Carolien R Mark MT et a1 | 2003 | J Autism Dev Disord2003，33，5： | 1 |
| 7 | mRNA turnover rate limits siRNA and microRNA efficacy显示文摘 | Larsson E Sander C Marks D | 2010 | Mol Syst Biol2010，6，： | 1 |
| 8 | STEM,STEM Education,STEM mania显示文摘 | Mark Sanders | 2009 | The Technology Teacher2009，68，4： | 1 |
| 9 | Reflux and irritable bowel syndrome are negative predictors of quality of life in coeliac disease and inflammatory bowel disease显示文摘 | Stephen M. Barratt John S. Leeds Kerry Robinson Premal J. Shah Alan J. Lobo Mark E. McAlindon David S. Sanders | 2011 | European Journal of Gastroenterology & Hepatology2011，，： | 1 |
| 10 | A real time RT-PCR assay for the specific detection of Peste des petits ruminants virus显示文摘 | Carrie A. Batten Ashley C. Banyard Donald P. King Mark R. Henstock Lorraine Edwards Anna Sanders Hubert Buczkowski Chris C.L. Oura Tom Barrett | 2010 | Journal of Virological Methods2010，，2： | 1 |
| 11 | Evaluating the role of small-bowel endoscopy in clinical practice: the largest single-centre experience显示文摘 | Reena Sidhu Mark E. McAlindon Kaye Drew Suzanne Hardcastle Iain C. Cameron David S. Sanders | 2012 | European Journal of Gastroenterology & Hepatology2012，，5： | 1 |
| 12 | Disentangling the drivers of β diversity along latitudinal and elevational gradients 显示文摘 | Kraft NJB Comita LS Chase JM Sanders NJ Swenson NG Crist TO Stegen JC Mark V Brad B Anderson MJ | 2011 | Science2011，333，6050： | 1 |
| 13 | Tranexamic acid for intracerebral haemorrhage within 2 hours of onset: protocol of a phase Ⅱ randomised placebo-controlled double-blind multicentre trial显示文摘Rationale Haematoma growth is common early after intracerebral haemorrhage(ICH),and is a key determinant of outcome.Tranexamic acid,a widely available antifibrinolytic agent with an excellent safety profile,may reduce haematoma growth.Methods and design Stopping intracerebral haemorrhage with tranexamic acid for hyperacute onset presentation including mobile stroke units(STOP-MSU)is a phase Ⅱ double-blind,randomised,placebo-controlled,multicentre,international investigator-led clinical trial,conducted within the estimand statistical framework.Hypothesis In patients with spontaneous ICH,treatment with tranexamic acid within 2 hours of onset will reduce haematoma expansion compared with placebo.Sample size estimates A sample size of 180 patients(90 in each arm)would be required to detect an absolute difference in the primary outcome of 20%(placebo 39%vs treatment 19%)under a two-tailed significance level of 0.05.An adaptive sample size re-estimation based on the outcomes of 144 patients will allow a possible increase to a prespecified maximum of 326 patients.Intervention Participants will receive 1 g intravenous tranexamic acid over 10 min,followed by 1 g intravenous tranexamic acid over 8 hours;or matching placebo.Primary efficacy measure The primary efficacy measure is the proportion of patients with haematoma growth by 24±6 hours,defined as either≥33%relative increase or≥6 mL absolute increase in haematoma volume between baseline and follow-up CT scan.Discussion We describe the rationale and protocol of STOP-MSU,a phase Ⅱ trial of tranexamic acid in patients with ICH within 2 hours from onset,based in participating mobile stroke units and emergency departments. | Nawaf Yassi Henry Zhao Leonid Churilov Bruce C V Campbell Teddy Wu Henry Ma Andrew Cheung Timothy Kleinig Helen Brown Philip Choi Jiann-Shing Jeng Annemarei Ranta Hao-Kuang Wang Geoffrey C Cloud Rohan Grimley Darshan Shah Neil Spratt Der-Yang Cho Karim Mahawish Lauren Sanders John Worthington Ben Clissold Atte Meretoja Vignan Yogendrakumar Mai Duy Ton Duc Phuc Dang Nguyen Thai My Phuong Huy-Thang Nguyen Chung Y Hsu Gagan Sharma Peter J Mitchell Bernard Yan Mark W Parsons Christopher Levi Geoffrey A Donnan Stephen M Davis | 2022 | Stroke & Vascular Neurology2022，7，2： | 1 |
| 14 | Prediction of human microRNA targets显示文摘 | JOHN B SANDER C MARKS D S | 2006 | Methods in Molecular Biology (Clifton NJ)2006，342，1： | 1 |
| 15 | Prediction of human microRNA targets显示文摘 | John B Sander C Marks DS | 2006 | Methods Mol Biol2006，342，： | 1 |
| 16 | Relation between pO 2 , 31 P magnetic resonance spectroscopy parameters and treatment outcome in patients with high-grade soft tissue sarcomas treated with thermoradiotherapy显示文摘 | Mark W. Dewhirst Jean M. Poulson Daohai Yu Linda Sanders Micha?l Lora-Michiels Zeljko Vujaskovic Ellen L. Jones Thaddeus V. Samulski Barbara E. Powers David M. Brizel Leonard R. Prosnitz H. Cecil Charles | 2005 | International Journal of Radiation Oncology Biology Physics2005，，2： | 1 |
| 17 | miR-122,a mammalian liver-specific microRNA,is processed from hcr mRNA and may downregulate the high affinity cationic amino acid transporter CAT-1显示文摘 | Chang J Nicolas E Marks D Sander C Lerro A Buendia MA | 2004 | RNA Biol2004，1，2： | 1 |
| 18 | Prediction of human microRNA targets 显示文摘 | John B Sander C Marks DS | 2006 | Methods Mol Biol2006，342，： | 1 |
| 19 | miR-122, a mammalian liver-specific microRNA, is processed from hcr mRNA and may downregulate the high affinity cationic amino acid transporter CAT-1 显示文摘 | Chang J Nicolas E Marks D Sander C Lerro A Buendia MA | 2004 | RNA Biol2004，1，2： | 1 |
| 20 | Identification of virus-encoded microRNAs 显示文摘 | Pfeffer S Zavolan M Grasser FA Chien M Russo JJ Ju J John B Enright AJ Marks D Sander C Tuschl T | 2004 | Science2004，304，5671： | 1 |
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