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| 1 | 多模态语篇分析的进展与前沿显示文摘1990年代以来,功能语言学与语篇分析的多模态转向使多模态语篇分析成为语言学与传播学研究的热点之一。近年来,多模态研究逐渐从将语言学理论简单应用于图像、手势等非语言符号的分析,转向对多模态表意资源的跨学科系统阐释与实证研究。因此,具有独特理论体系和分析方法的多模态研究正成为一个新兴的人文学科。一方面,融合语言学、传媒学、认知心理学等学科的跨学科理论体系正在形成并被应用于阐释动态语篇等更复杂的符号与行为体系;另一方面,应用电脑模拟、语料库检索等数字技术的新型研究工具和方法迅速发展。多模态分析的理论与方法也逐渐被应用于课堂教学、广告传媒、法庭辩论等各种社会行为和语篇的研究。 | 冯德正 张德禄 Kay O'Halloran | 2014 | 当代语言学2014，16，1： | 112 |
| 2 | Revisions to the Tumor,Node,Metastasis staging of lung cancer(8th edition):Rationale,radiologic findings and clinical implications显示文摘The Tumor, Node, Metastasis(TNM) staging system,adopted by the Union for International Cancer Control(UICC) and the American Joint Committee on Cancer(AJCC), has been recently revised, with the new 8^(th) edition of the staging manual being published in January 2017. This edition has few but important evidencebased changes to the TNM staging system used for lung cancer. Radiologists should be aware of the updated classification system to accurately provide staging information to oncologists and oncosurgeons. In this article, we discuss the rationale, illustrate the changes with relevance to Radiology, and review the clinical implications of the 8^(th) edition of the UICC/AJCC TNM staging system with regards to lung cancer. | Fernando U Kay Asha Kandathil Kiran Batra Sachin S Saboo Suhny Abbara Prabhakar Rajiah | 2017 | World Journal of Radiology2017，9，6： | 39 |
| 3 | Electro-acupuncture to prevent prolonged postoperative ileus:A randomized clinical trial显示文摘AIM:To examine whether acupuncture can prevent prolonged postoperative ileus(PPOI)after intraperitoneal surgery for colon cancer. METHODS:Ninety patients were recruited from the Fudan University Cancer Hospital,Shanghai,China. After surgery,patients were randomized to receive acupuncture(once daily,starting on postoperative day 1, for up to six consecutive days)or usual care.PPOI was defined as an inability to pass flatus or have a bowel movement by 96 h after surgery.The main outcomes were time to first flatus,time to first bowel movement, and electrogastroenterography.Secondary outcomes were quality of life(QOL)measures,including pain, nausea,insomnia,abdominal distension/fullness,and sense of well-being. RESULTS:No significant differences in PPOI on day 4 (P=0.71)or QOL measures were found between the groups.There were also no group differences when the data were analyzed by examining those whose PPOI had resolved by day 5(P=0.69)or day 6(P= 0.88).No adverse events related to acupuncture were reported. CONCLUSION:Acupuncture did not prevent PPOI andwas not useful for treating PPOI once it had developed in this population. | M Kay Garcia Joseph S Chiang Bob Thornton J Lynn Palmer Jennifer McQuade Lorenzo Cohen | 2010 | World Journal of Gastroenterology2010，16，1： | 27 |
| 4 | Biomarkers in diabetic nephropathy: Present and future显示文摘Diabetic nephropathy(DN) is the leading cause of end stage renal disease in the Western world. Microalbuminuria(MA) is the earliest and most commonly used clinical index of DN and is independently associated with cardiovascular risk in diabetic patients. Although MA remains an essential tool for risk stratification and monitoring disease progression in DN, a number of factors have called into question its predictive power. Originally thought to be predictive of future overt DN in 80% of patients, we now know that only around 30% of microalbuminuric patients progress to overt nephropathy after 10 years of follow up. In addition, advanced structural alterations in the glomerular basement membrane may already have occurred by the time MA is clinically detectable.Evidence in recent years suggests that a significant proportion of patients with MA can revert to normoalbuminuria and the concept of nonalbuminuric DN is well-documented, reflecting the fact that patients with diabetes can demonstrate a reduction in glomerular filtration rate without progressing from normo-to MA. There is an unmet clinical need to identify biomarkers with potential for earlier diagnosis and risk stratification in DN and recent developments inthis field will be the focus of this review article. | Gemma Currie Gerard Mc Kay Christian Delles | 2014 | World Journal of Diabetes2014，5，6： | 26 |
| 5 | Characteristics of hepatocellular carcinoma in cirrhotic and non-cirrhotic non-alcoholic fatty liver disease显示文摘AIM: To determine characteristics and prognosticpredictors of patients with hepatocellular carcinoma(HCC) in association with non-alcoholic fatty liver disease(NAFLD).METHODS: We reviewed the records of all patients with NAFLD associated HCC between 2000 and 2012. Data collected included demographics; histology; presence or absence of cirrhosis, size and number of HCC, alpha-fetoprotein, body mass index(BMI), and the presence of diabetes, hypertension, or dyslipidaemia.RESULTS: Fifty-four patients with NAFLD associated HCC were identified. Mean age was 64 years with 87% male. Fifteen percent(8/54) were not cirrhotic. 11%, 24% and 50% had a BMI of < 25 kg/m2, 25-29 kg/m2 and ≥ 30 kg/m2 respectively. Fifty-nine percent were diabetic, 44% hypertensive and 26% hyperlipidaemic. Thirty-four percent of the patients had ≤ 1 of these risk factors. Non-cirrhotics had a significantly larger mean tumour diameter at diagnosis than cirrhotics(P = 0.041). Multivariate analysis did not identify any other patient characteristics that predicted the size or number of HCC.CONCLUSION: HCC can develop in NAFLD without cirrhosis. At diagnosis such tumours are larger than those in cirrhotics, conferring a poorer prognosis. | Christopher Leung Sern Wei Yeoh Desmond Patrick Shara Ket Kaye Marion Paul Gow Peter W Angus | 2015 | World Journal of Gastroenterology2015，21，4： | 24 |
| 6 | 美国国立老化研究所与阿尔茨海默病协会诊断指南写作组:阿尔茨海默病临床前阶段的定义显示文摘阿尔茨海默病(AD)的病理生理过程在痴呆诊断的多年前就开始了。这一长期的AD“临床前”阶段是治疗干预的关键机会,但需进一步阐明AD的病理级联过程和临床症状出现之间的联系。美国国立老化研究所和AD协会召集了一个国际工作组对AD生物标志物、流行病学和神经心理学的证据进行综述并提出建议,以确定能够预测由“正常”认知到轻度认知功能障碍(MCI)及AD痴呆的最佳预测指标。根据目前已有的主要科学证据,我们提出了一个概念性的框架和用于操作的研究标准,以通过纵向临床研究来验证和改进这些模型。这些建议仅用于研究目的,目前不涉及临床应用。我们希望这些建议能提供一个共识,以推进临床前AD的研究,最终推动更早期治疗干预的进展,使得一些疾病减缓药物的疗效发挥最大。 | Sperling RA Aisen PS Beckett LA Bennett DA Craft S Fagan AM Iwatsubo T Jack CR Jr Kaye J Montine TJ Park DC Reiman EM Rowe CC Siemers E Stern Y Yaffe K Carrillo MC Thies B Morrison-Bogorad M Wagster MV Phelps CH 贾建平(译) 郭起浩(译) 黄丽(译) 陆璐(译) 张逸驰(译) 邢怡(译) | 2012 | 中华神经科杂志2012，45，5： | 22 |
| 7 | SPIRIT 2013声明:定义临床研究方案的标准条目显示文摘临床研究方案是临床研究设计、实行、报告和评价的基础。然而,临床研究方案及现存的临床研究方案指引在内容和质量上差异很大。本文描述了《规范临床研究方案内容》(Standard Protocol Items:Recommendations for Interventional Trials 2013 ),简称SPIRIT2013声明,一个临床研究方案必须报告的条目指引的系统建立和范围。 | An-Wen Chan Jennifer M.Tetzlaff Douglas G.Altman Andreas Laupacis Peter C.GΦtzsche Karmela Krleza-Jeri AsbjΦrn Hróbjartsson Howard Mann Kay Dickersin Jesse A.Berlin Caroline J.Doré Wendy R.Parulekar William S.M.Summerskill Trish Groves Kenneth F.Schulz Harold C.Sox Frank W.Rockhold Drummond Rennie David Moher 钟丽丹 郑颂华 吴泰相 李幼平 商洪才 张伯礼 唐旭东 吕爱平 卞兆祥 | 2013 | 中国循证医学杂志2013，13，12： | 23 |
| 8 | 经直肠超声引导自动活检枪前列腺穿刺260例分析显示文摘目的 :研究经直肠超声引导自动活检枪前列腺穿刺在诊断早期前列腺癌方面的意义。方法 :患者分为两组 ,第 1组 2 30例为经每年一次 PSA筛选 ,PSA>4μg/ L而进行直肠指检 (DRE)和经直肠超声引导自动活检枪穿刺 (TRU S)加活检的澳大利亚患者 ;第 2组 30例为 DRE有可疑结节而进行 TRUS加活检的国内病例。结果 :经直肠超声引导自动活检枪前列腺穿刺所获标本取材全部优良 ,符合病理诊断的要求。第 1组检出前列腺癌82例 ,其中 T2 a期以内 80例 ,T2 b 2例 ,不典型增生 19例 ;第 2组检出前列腺癌 8例 ,其中 1例属 T2 b,已行根治性前列腺切除术 ,另外 7例至少在 T3期以上。所有患者穿刺后未发生严重并发症。结论 :经直肠超声引导自动活检枪前列腺穿刺是确诊早期前列腺癌的重要的方法 ,而且并发症少 ,值得推广。 | 白强 张华卿 王振声 李青 Keith W Kaye | 2001 | 临床泌尿外科杂志2001，16，9： | 17 |
| 9 | Regression of cirrhosis during treatment with tenofovir disoproxil fumarate for chronic hepatitis B: a 5-year open-label follow-up study显示文摘 | Patrick Marcellin Edward Gane Maria Buti Nezam Afdhal William Sievert Ira M Jacobson Mary Kay Washington George Germanidis John F Flaherty Raul Aguilar Schall Jeffrey D Bornstein Kathryn M Kitrinos G Mani Subramanian John G McHutchison E Jenny Heathcote | 2012 | The Lancet2012，，： | 14 |
| 10 | 保留尿道括约功能的前列腺癌根治术165例报告显示文摘目的 探讨保留尿道括约功能的前列腺癌根治术后病人发生尿失禁的影响因素。 方法 采用尿道外括约肌保留、膀胱颈及前列腺前括约肌 (PPS)保留、勃起神经保留等方法行前列腺根治手术 16 5例。通过调查表和尿垫试验 ,从主观和客观两方面进行随访。 结果 尿道外括约肌保留组尿失禁发生率为 0 .7% ,括约肌修复组为 5 .3% ;按年龄分组 :5 0岁~组拔除导尿管时 ,6 0 %出现尿失禁 ,6 0岁~组拔除导尿管时 ,82 %出现尿失禁。但 3个月以后 ,两组趋于一致。 结论 外科技术和病人年龄是影响根治性前列腺切除术后尿失禁发生的重要因素 ,保留尿道外括约肌及保留尿控制机制可以减少术后尿失禁发生率。年轻病人术后易恢复尿控状态 。 | 白强 王振声 李青 Glenice wilson Margaret McCarthy Keith W Kaye | 2001 | 中华泌尿外科杂志2001，22，8： | 14 |
| 11 | Evaluating the Effect of Tillage on Carbon Sequestration Using the Minimum Detectable Difference Concept显示文摘Three long-term field trials in humid regions of Canada and the USA were used to evaluate the influence of soil depth and sample numbers on soil organic carbon (SOC) sequestration in no-tillage (NT) and moldboard plow (MP) corn (Zea mays L.) and soybean (Glycine max L.) production systems. The first trial was conducted on a Maryhill silt loam (Typic Hapludalf) at Elora, Ontario, Canada, the second on a Brookston clay loam (Typic Argiaquoll) at Woodslee, Ontario, Canada, and the third on a Thorp silt loam (Argiaquic Argialboll) at Urbana, Illinois, USA. No-tillage led to significantly higher SOC concentrations in the top 5 cm compared to MP at all 3 sites. However, NT resulted in significantly lower SOC in sub-surface soils as compared to MP at Woodslee (10-20 cm, P = 0.01) and Urbana (20-30 cm, P < 0.10). No-tillage had significantly more SOC storage than MP at the Elora site (3.3 Mg C ha-1) and at the Woodslee site (6.2 Mg C ha-1) on an equivalent mass basis (1350 Mg ha-1 soil equivalent mass). Similarly, NT had greater SOC storage than MP at the Urbana site (2.7 Mg C ha-1) on an equivalent mass basis of 675 Mg ha-1 soil. However, these differences disappeared when the entire plow layer was evaluated for both the Woodslee and Urbana sites as a result of the higher SOC concentrations in MP than in NT at depth. Using the minimum detectable difference technique, we observed that up to 1500 soil sample per tillage treatment comparison will have to be collected and analyzed for the Elora and Woodslee sites and over 40 soil samples per tillage treatment comparison for the Urbana to statistically separate significant differences in the SOC contents of sub-plow depth soils. Therefore, it is impracticable, and at the least prohibitively expensive, to detect tillage-induced differences in soil C beyond the plow layer in various soils. | X. M. YANG C. F. DRURY M. M. WANDER B. D. KAY | 2008 | Pedosphere2008，18，4： | 11 |
| 12 | Diagnostic utility of IgG and IgM immunohistochemistry in autoimmune liver disease显示文摘AIM:To assess the role of IgM and IgG immunohistochemistry(IHC) in the evaluation of autoimmune liver conditions-autoimmune hepatitis(AIH),primary biliary cirrhosis(PBC),and primary sclerosing cholangitis(PSC).METHODS:Forty one biopsies from untreated patients diagnosed with autoimmune liver disease(AIH,n = 20;PBC,n = 13;PSC,n = 8) and fourteen biopsies of patients with chronic hepatitis C were selected.IgM and IgG-positive plasma cells were counted in each sample.RESULTS:A predominance of IgG-positive plasma cells was seen in AIH(90% of cases),PSC(75% of cases),and chronic hepatitis C(100% of cases),while IgMpositive plasma cells predominated in PBC(92.8% ofcases).The IgM /IgG ratio(< 1 or ≥ 1) accurately distinguished PBC from AIH in 90.9% of cases(sensitivity = 92.3%,specificity = 90%),and PBC from either AIH or PSC in 87.8% of cases(sensitivity = 92.3%,specificity = 85.7%).CONCLUSION:Plasmacytic infiltrates expressing predominantly IgM are characteristic of PBC,while other forms of liver disease analyzed in this study,including AIH,typically show an IgG-predominant plasma cell infiltrate.Our data indicate that IgM and IgG IHC may be a useful tool when PBC is a diagnostic consideration. | Roger Klein Moreira Frank Revetta Elizabeth Koehler Mary Kay Washington | 2010 | World Journal of Gastroenterology2010，16，4： | 11 |
| 13 | 粗粒度并行遗传算法收敛性分析及优化运算显示文摘提出了一种新型的粗粒度并行遗传算法 ( CGGA) ,该算法利用多个子种群基于不同的编码方式进行进化计算 .首先各子群体独立进行交叉、变异和选择遗传操作 ,每代进化后迁移算子被引入用来进行种群间的信息交流 ,迁移算子将各个子种群的最优个体替换相邻种群最差个体后继续进化 .基于时齐遍历马尔可夫链理论 ,给出了 CGGA各个子种群的概率转移矩阵与其进化概率转移矩阵 ,证明了以概率 1全局收敛 .对典型的测试函数 CGGA进行了求解 .仿真结果表明 ,本算法的收敛性能优于经典遗传算法 ( CGA) ,可以有效解决 | 戴晓明 陈昌领 邵惠鹤 Kay Das 程铁鹏 茅雪飞 | 2003 | 上海交通大学学报2003，37，4： | 11 |
| 14 | 辅助沟通系统概要显示文摘在中国,康复及相关专业在近十年发展快速,生活质量成为急性医疗照护之后的首要重点。沟通是人类特有且重要的技能,也是影响生活质量的重要因素之一。人类利用沟通将想法分享给其他人,也用沟通为自己的权益发声。本文宗旨是介绍辅助沟通的基本概念,包含辅助沟通简介、辅助沟通类型、可从辅助沟通获益的族群、辅助沟通语言介入服务原则,以及跨专业团队成员角色讨论。 | Szu-Han Kay Chen Katya Hill 孙克兴 褚立希 | 2012 | 中国康复理论与实践2012，18，9： | 11 |
| 15 | 系统综述与网状Meta分析的PRISMA扩展声明显示文摘PRISMA声明旨在提高系统综述和META分析报告的完整性,该声明已经广泛用于指导系统综述和META分析的报告和发表。原始的PRISMA声明是针对两种干预措施比较的传统的系统综述与META分析而制定的,然而,随着多种干预措施比较的系统综述的发展,实施和报告这一类系统综述面临较大挑战。此时,针对网状META分析的PRISMA扩展声明应运而生,旨在提高网状META分析系统综述的报告质量。PRISMA扩展声明是由专家们通过DELPHI调查、面对面讨论和共识大会而最终确立的。PRISMA扩展声明是在原始PRISMA声明的报告清单的基础上经过修改,最终确定了32个条目,每个条目均与网状META分析报告的内容直接相关。本文对网状META分析的PRISMA扩展声明进行了阐述,对报告清单各条目进行了举例说明,并详细说明了在原始PRISMA声明的基础上新增和修改各条目的理由。此外,PRISMA扩展声明强调了在网状META分析的实际操作中需要重点关注的信息。本文的目标读者包括网状META分析的作者与读者,以及期刊杂志的编辑与同行评审。 | 李志霞 杨俊 叶欣 周凌波 杨智荣 孙凤 詹思延 Brian Hutton Georgia Salanti Deborah M.Caldwell Anna Chaimani Christopher H.Schmid Chris Cameron John P.A.Ioannidis Sharon Straus Kristian Thorlund Jeroen P.Jansen Cynthia Mulrow Ferrán Catalá-López Peter C.Gozsche Kay Dickersin Isabelle Boutron Douglas G.Altman David Moher | 2016 | 中国循证心血管医学杂志2016，8，6： | 11 |
| 16 | Recent advances on phylogenomics of gymnosperms and a new classification显示文摘Living gymnosperms comprise four major groups:cycads,Ginkgo,conifers,and gnetophytes.Relationships among/within these lineages have not been fully resolved.Next generation sequencing has made available a large number of sequences,including both plastomes and single-copy nuclear genes,for reconstruction of solid phylogenetic trees.Recent advances in gymnosperm phylogenomic studies have updated our knowledge of gymnosperm systematics.Here,we review major advances of gymnosperm phylogeny over the past 10 years and propose an updated classification of extant gymnosperms.This new classification includes three classes(Cycadopsida,Ginkgoopsida,and Pinopsida),five subclasses(Cycadidae,Ginkgoidae,Cupressidae,Pinidae,and Gnetidae),eight orders(Cycadales,Ginkgoales,Araucariales,Cupressales,Pinales,Ephedrales,Gnetales,and Welwitschiales),13 families,and 86 genera.We also described six new tribes including Acmopyleae Y.Yang,Austrocedreae Y.Yang,Chamaecyparideae Y.Yang,Microcachrydeae Y.Yang,Papuacedreae Y.Yang,and Prumnopityeae Y.Yang,and made 27 new combinations in the genus Sabina. | Yong Yang David Kay Ferguson Bing Liu Kang-Shan Mao Lian-Ming Gao Shou-Zhou Zhang Tao Wan Keith Rushforth Zhi-Xiang Zhang | 2022 | Plant Diversity2022，44，4： | 10 |
| 17 | 光动力学疗法辅助手术治疗脑恶性肿瘤显示文摘本文报告应用激光 血卟啉衍生物辅助手术治疗26例脑恶性肿瘤,其中21例为恶性胶质瘤4例为脑转移癌,1例为恶性脑膜瘤。我们认为应用4~7mg/kg体重HPD和波长630nm激光.剂量达到300J/cm辅助手术治疗脑恶性胂瘤未增加并发症的发生.且取得了较好的治疗效果。 | 朱树干 周茂德 张成 鲍秀峰 李新钢 庞琦 吴思恩 陈增谦 赵献光 孙向东 Andrew H Kaye M.D | 1993 | 中国肿瘤临床1993，20，12： | 10 |
| 18 | 湖南烟溪病圃稻瘟病菌的有性态及微卫星标记的遗传多样性分析显示文摘用 2对稻瘟病菌的两性能育菌株 (交配型 1.1和交配型 1.2 )测定了来自湖南烟溪病圃上的 4年 12 4个稻瘟病菌株的交配型 ,用微卫星分子标记分析其中 10 5个菌株的遗传多样性及其亲缘关系。12 4个菌株中 ,2 8个为交配型 1.1,39个为交配型 1.2 ,5 7个不育 ,分别占供试菌株的 2 2 .5 8%、31.4 5 %和 4 5 .97% ;在 0 .6 7相似性的基础上 ,7对微卫星引物扩增出的标记可将 10 5个菌株区分为 6个系谱群。 | 沈瑛 Julien FROUIN 何月秋 Claudia KAYE 肖放 Jean Loup NOTTEGHEM 刘二 Didier THARREAU | 2004 | 中国水稻科学2004，18，3： | 10 |
| 19 | 稻瘟病菌株CH63和TH16杂交组合的遗传图谱构建及无毒基因定位显示文摘测定了CH63和TH16杂交后代(F1 代子囊孢子群体)在36个水稻品种上的致病性,依据F1 代子囊孢子群体在不同品种上的无毒性/毒性表型和SSR、SCAR和RAPD等分子标记的多态性位点共分离构建了稻瘟病菌的遗传图谱。图谱共有151个标记位点,7个连锁群,全长1038.4 cM。由杂交后代在不同品种上的无毒性/毒性分离鉴定出CH63菌株持有多个无毒基因,在该遗传图谱中初步定位了Avr2 K59、Avr C105 TTP1、Avr Zh156、Avr Xuan1641、Avr Xuan6392 和Avr C103 TTP 6个无毒基因,分别定位在第1、第4和第7染色体上。 | 王艳丽 Claudia KAYE Amandine BORDAT Henri ADREIT Jo■lle MILLAZZO 郑小波 沈瑛 Didier THARREAU | 2005 | 中国水稻科学2005，19，2： | 9 |
| 20 | 高纤维膳食和补充乙酸盐改变肠道菌群,预防醋酸脱氧皮质酮-盐型高血压小鼠高血压和心力衰竭的发展显示文摘水果和蔬菜的膳食摄入与高血压的发生率较低有关,但所涉及的机制尚未阐明。该研究评估了高纤维膳食和短链脂肪酸(short-chain fatty acid,SCFA)(乙酸盐)对肠道微生物群和预防心血管病的影响。方法:用盐皮质激素诱发小鼠高血压模型,观测正常喂食组、高纤维喂食组和补充乙酸盐组的肠道微生物、心脏结构/功能和血压水平。 | 刘莉 叶鹏 Marques FZ Nelson EM Chu PY Horlock D Fiedler A Ziemann M Tan JK Kuruppu S Rajapakse NW El-Osta A Mackay CR Kaye DM | 2016 | 中华高血压杂志2016，24，12： | 8 |
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