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| 1 | Long‐term entecavir therapy results in the reversal of fibrosis/cirrhosis and continued histological improvement in patients with chronic hepatitis B显示文摘 | Ting‐Tsung Chang Yun‐Fan Liaw Shun‐Sheng Wu Eugene Schiff Kwang‐Hyub Han Ching‐Lung Lai Rifaat Safadi Samuel S. Lee Waldemar Halota Zachary Goodman Yun‐Chan Chi Hui Zhang Robert Hindes Uchenna Iloeje Suzanne Beebe Bruce Kreter | 2010 | Hepatology2010，，： | 4 |
| 2 | Prognostic significance of hepatic encephalopathy in patients with cirrhosis treated with current standards of care显示文摘BACKGROUND Hepatic encephalopathy(HE)is a reversible neuropsychiatric complication of liver cirrhosis and occurs in up to 50%of cirrhotic patients.Studies examining the prognostic significance of HE are limited despite the high prevalence in cirrhosis.AIM To define the clinical outcomes of patients after an episode of HE treated with current standards-of-care.METHODS All patients hospitalised with HE requiring Rifaximin to 3 tertiary centres over46-mo(2012–2016)were identified via pharmacy dispensing records.Patients with hepatocellular carcinoma and those prescribed Rifaximin prior to admission were excluded.Medical records were reviewed to determine baseline characteristics and survival.The Kaplan-Meier method was used to calculate survival probability.Univariate survival analysis was performed with variables reaching statistical significance included in a multivariate analysis.The primary outcome was 12-mo mortality following commencement of Rifaximin.RESULTS188 patients were included.Median age was 57 years(IQR 50-65),71%were male and median model for end stage liver disease and Child Pugh scores were 25(IQR 18-31)and 11(IQR 9-12)respectively.The most common causes of cirrhosis were alcohol(62%),hepatitis C(31%)and non-alcoholic fatty liver disease(20%).A precipitating cause for HE was found in 92%patients with infection(43%),GI bleeding(16%),medication non-compliance(15%)and electrolyte imbalance(14%)the most common.During a mean follow up period of 12±13 mo 107(57%)patients died and 32(17%)received orthotopic liver transplantation.Themost common causes of death were decompensated chronic liver disease(57%)and sepsis(19%).The probability of survival was 44%and 35%at 12-and 24-mo respectively.At multivariate analysis a model for end stage liver disease>15 and international normalised ratio reached statistical significance in predicting mortality.CONCLUSION Despite advances made in the management of HE patients continue to have poor survival.Thus,in all patients presenting with HE the appropriateness of orthotopic liver transplantation should be considered. | Anuj Bohra Thomas Worland Samuel Hui Ryma Terbah Ann Farrell Marcus Robertson | 2020 | World Journal of Gastroenterology2020，26，18： | 4 |
| 3 | Increased activity of the complement system in the liver of patients with alcoholic hepatitis显示文摘 | Hong Shen Barbara A. French Hui Liu Brittany C. Tillman Samuel W. French | 2014 | Experimental and Molecular Pathology2014，，3： | 2 |
| 4 | TLR3/4 signaling is mediated via the NFκB-CXCR4/7 pathway in human alcoholic hepatitis and non-alcoholic steatohepatitis which formed Mallory–Denk bodies显示文摘 | Hui Liu Jun Li Brittany Tillman Timothy R. Morgan Barbara A. French Samuel W. French | 2014 | Experimental and Molecular Pathology2014，，2： | 2 |
| 5 | Chanson:Hydrodynamic load balancing显示文摘 | Hui Chi-Chung Samuel T | 1999 | IEEE Transaction Parallel Distributed System1999，10，11： | 1 |
| 6 | 3D Conformal radiotherapy for gastric cancer—results of a comparative planning study显示文摘 | Trevor Leong David Willis Daryl Lim Joon Sara Condron Andrew Hui Samuel Y.K. Ngan | 2005 | Radiotherapy and Oncology2005，，3： | 1 |
| 7 | Chanson : hydrodynamic load balancing 显示文摘 | HUI C C SAMUEL T | 1999 | IEEE Transactions on Parallel and Distributed Systems1999，10，11： | 1 |
| 8 | Minimal communication cost software construction in the Internet environment 显示文摘 | Hui Chi-Chung Samuel T C | 1997 | Acta Informatica1997，34，8： | 1 |
| 9 | Comprehensive molecular diagnosis of 179 Leber congenital amaurosis and juvenile retinitis pigmentosa patients by targeted next generation sequencing显示文摘 | Xia Wang Hui Wang Vincent Sun Han-Fang Tuan Vafa Keser Keqing Wang Huanan Ren Irma Lopez Jacques E Zaneveld Sorath Siddiqui Stephanie Bowles Ayesha Khan Jason Salvo Samuel G Jacobson Alessandro Iannaccone Feng Wang David Birch John R Heckenlively Gerald A | 2013 | Journal of Medical Genetics2013，，10： | 1 |
| 10 | Deficiency of intestinal mucin‐2 ameliorates experimental alcoholic liver disease in mice显示文摘 | Phillipp Hartmann Peng Chen Hui J. Wang Lirui Wang Declan F. McCole Katharina Brandl Peter St?rkel Clara Belzer Claus Hellerbrand Hidekazu Tsukamoto Samuel B. Ho Bernd Schnabl | 2013 | Hepatology2013，，： | 1 |
| 11 | Tire-derived carbon for catalytic preparation of biofuels from feedstocks containing free fatty acids显示文摘The utilization of waste feedstocks rich in free fatty acids(FFAs)improves biofuel production on the basis of economics and sustainability.However,converting these feedstocks to usable biofuel poses inherent problems in terms of the FFA to biofuel conversion yield and the catalyst lifetime.Here,we report novel ferric sulfate impregnated carbon derived from waste tires as highly active catalysts for FFA to biofuel conversion.Our approach takes advantage of facile synthesis methods involving sonication and dehydration processes to create materials that are useful for the efficient catalytic conversion of FFAs to advanced biofuels.Esterification of FFAs to fatty acid methyl esters was achieved at 65C and atmospheric pressure with>98%yield even in the presence of triglycerides.These catalysts maintained similar activity after four successive uses,which indicates that the active catalytic sites are effectively supported by the three-dimensional meso/microporous architecture of the tire-derived carbon. | Zachary D.Hood Shiba P.Adhikari Samuel F.Evans Hui Wang Yunchao Li Amit K.Naskar Miaofang Chi Abdou Lachgar M.Parans Paranthaman | 2018 | Carbon Resources Conversion2018，1，2： | 0 |
| 12 | Natural history and outcomes of patients with liver cirrhosis complicated by hepatic hydrothorax显示文摘BACKGROUNDHepatic hydrothorax (HH) is an uncommon and difficult-to-manage complicationof cirrhosis with limited treatment options.AIMTo define the clinical outcomes of patients presenting with HH managed withcurrent standards-of-care and to identify factors associated with mortality.METHODSCirrhotic patients with HH presenting to 3 tertiary centres from 2010 to 2018 wereretrospectively identified. HH was defined as pleural effusion in the absence ofcardiopulmonary disease. The primary outcomes were overall and transplant-freesurvival at 12-mo after the index admission. Cox proportional hazards analysiswas used to determine factors associated with the primary outcomes.RESULTSOverall, 84 patients were included (mean age, 58 years) with a mean model forend-stage liver disease score of 29. Management with diuretics alone achievedlong-term resolution of HH in only 12% patients. At least one thoracocentesis wasperformed in 73.8% patients, transjugular intrahepatic portosystemic shuntinsertion in 11.9% patients and 33% patients received liver transplantation within12-mo of index admission. Overall patient survival and transplant-free survival at12 mo were 68% and 41% respectively. At multivariable analysis, current smoking [hazard ratio (HR) = 8.65, 95% confidence interval (CI): 3.43-21.9, P < 0.001) and acute kidneyinjury (AKI) (HR = 2.91, 95%CI: 1.21-6.97, P = 0.017) were associated with a significantly increasedrisk of mortality.CONCLUSIONCirrhotic patients with HH are a challenging population with a poor 12-mo survival despitecurrent treatments. Current smoking and episodes of AKI are potential modifiable factors affectingsurvival. HH is often refractory of diuretic therapy and transplant assessment should beconsidered in all cases. | Sarah Romero Andy KH Lim Gurpreet Singh Chamani Kodikara Rachel Shingaki-Wells Lynna Chen Samuel Hui Marcus Robertson | 2022 | World Journal of Gastroenterology2022，28，35： | 0 |
| 13 | Influence of Halide Choice on Formation of Low-Dimensional Perovskite Interlayer in Efficient Perovskite Solar Cells显示文摘Recent advances in heterojunction and interfacial engineering of perovskite solar cells(PSCs)have enabled great progress in developing highly efficient and stable devices.Nevertheless,the effect of halide choice on the formation mechanism,crystallography,and photoelectric properties of the lowdimensional phase still requires further detailed study.In this work,we present key insights into the significance of halide choice when designing passivation strategies comprising large organic spacer salts,clarifying the effect of anions on the formation of quasi-2D/3D heterojunctions.To demonstrate the importance of halide influences,we employ novel neo-pentylammonium halide salts with different halide anions(neoPAX,X=I,Br,or Cl).We find that regardless of halide selection,iodide-based(neoPA)_(2)(FA)_((n-1))PbnI_((3n+1))phases are formed above the perovskite substrate,while the added halide anions diffuse and passivate the perovskite bulk.In addition,we also find the halide choice has an influence on the degree of dimensionality(n).Comparing the three halides,we find that chloride-based salts exhibit superior crystallographic,enhanced carrier transport,and extraction compared to the iodide and bromide analogs.As a result,we report high power conversion efficiency in quasi-2D/3D PSCs,which are optimal when using chloride salts,reaching up to 23.35%,and improving long-term stability. | Xueping Liu Thomas Webb Linjie Dai Kangyu Ji Joel A.Smith Rachel C.Kilbride Mozhgan Yavari Jinxin Bi Aobo Ren Yuanyuan Huang Zhuo Wang Yonglong Shen Guosheng Shao Stephen J.Sweeney Steven Hinder Hui Li David G.Lidzey Samuel D.Stranks Neil C.Greenham S.Ravi P.Silva Wei Zhang | 2022 | Energy & Environmental Materials2022，5，2： | 0 |
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