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| 1 | Bone mineral density and disorders of mineral metabolism in chronic liver disease显示文摘AIM:To estimate the prevalence and identify the risk factors for metabolic bone disease in patients with cirrhosis.METHODS:The study was performed on 72 Indian patients with cirrhosis(63 male, 9 female;aged < 50 years).Etiology of cirrhosis was alcoholism(n = 37), hepatitis B(n = 25) and hepatitis C(n = 10).Twenty-three patients belonged to Child class A, while 39 were in class B and 10 in class C.Secondary causes for metabolic bone disease and osteoporosis were ruled out.Sunlight exposure, physical activity and dietary constituents were calculated.Complete metabolic profiles were derived, and bone mineral density(BMD) was measured using dual energy X ray absorptiometry.Low BMD was defined as a Z score below-2.RESULTS:Low BMD was found in 68% of patients.Lumbar spine was the most frequently and severely affected site.Risk factors for low BMD included low physical activity, decreased sunlight exposure, and low lean body mass.Calcium intake was adequate, with unfavorable calcium:protein ratio and calcium:phosphorus ratio.Vitamin D deficiency was highly prevalent(92%).There was a high incidence of hypogonadism(41%).Serum estradiol level was elevated significantly in patients with normal BMD.Insulin-like growth factor(IGF) 1 and IGF binding protein 3 levels were below the age-related normal range in both groups.IGF-1 was signiflcantly lower in patients with low BMD.Serum osteocalcin level was low(68%) and urinary deoxypyridinoline to creatinine ratio was high(79%), which demonstrated low bone formation with high resorption.CONCLUSION:Patients with cirrhosis have low BMD.Contributory factors are reduced physical activity, low lean body mass, vitamin D def iciency and hypogonadism and low IGF-1 level. | Joe George Hosahithlu K Ganesh Shrikrishna Acharya Tushar R Bandgar Vyankatesh Shivane Anjana Karvat Shobna J Bhatia Samir Shah Padmavathy S Menon Nalini Shah | 2009 | World Journal of Gastroenterology2009，15，28： | 15 |
| 2 | Metastatic clear cell variant of hepatocellular carcinoma with an occult hepatic primary显示文摘Metastatic clear cell carcinomas are commonly seen in the kidney and lung. Clear cell variant of hepatocellular carci- noma is an uncommon tumour. Diagnosis is usually made by correlation of histopathology. tumour markers and im- munohistochemistry, especially HepPar 1. In this unusual case of metastatic clear cell carcinoma presenting as Sister Mary Joseph’s nodule, no primary evidence was observed radiologically in the liver, but the level of alfa fetoprotein was markedly elevated. Metastatic clear cell carcinoma of the liver with an occult hepatic primary was diagnosed by immunohistochemical profile of the tumour. | Samir ShahSamir Shah Sudeep Gupta Tanuja Shet Amita Maheshwari Rekha Wuntkal and Kunisshery Mallath Mohandas | 2005 | Hepatobiliary & Pancreatic Diseases International2005，4，2： | 3 |
| 3 | SCH 503034, a Novel Hepatitis C Virus Protease Inhibitor, Plus Pegylated Interferon α-2b for Genotype 1 Nonresponders显示文摘 | Christoph Sarrazin Regine Rouzier Frank Wagner Nicole Forestier Dominique Larrey Samir K. Gupta Musaddeq Hussain Amrik Shah David Cutler Jenny Zhang Stefan Zeuzem | 2007 | Gastroenterology2007，，4： | 2 |
| 4 | The contemporary management of splenic artery aneurysms显示文摘 | Ryan O. Lakin James F. Bena Timur P. Sarac Samir Shah Leonard P. Krajewski Sunita D. Srivastava Daniel G. Clair Vikram S. Kashyap | 2011 | Journal of Vascular Surgery2011，，： | 2 |
| 5 | Association of Serum Bilirubin with Ischemic Stroke Outcomes显示文摘 | Sandra Pineda Oh Young Bang Jeffrey L. Saver Sidney Starkman Susan W. Yun David S. Liebeskind Doojin Kim Latisha K. Ali Samir H. Shah Bruce Ovbiagele | 2008 | Journal of Stroke and Cerebrovascular Diseases2008，，3： | 1 |
| 6 | Effect of counterions on surface and foaming properties of dodecyl sulfate显示文摘 | Rahul P Bagwe Dinesh O Shah | 2003 | Journal of Colloid and Interface Science2003，，267： | 1 |
| 7 | Creating Value through Enterprise Risk Management: A Practical Approach for the Insurance Industry 显示文摘 | Jerry Miccolis&Samir Shah | 2001 | Tillinghast-Towers Perrin Monograph2001，，： | 1 |
| 8 | Effects of statin therapy on the progression of chronic kidney disease显示文摘 | Samir Shah James Paparello Farhad R. Danesh | 2005 | Advances in Chronic Kidney Disease2005，，2： | 1 |
| 9 | Postoperative Mediastinitis in Children: Epidemiology, Microbiology and Risk Factors for Gram-Negative Pathogens显示文摘 | Caroline B. Long Samir S. Shah Ebbing Lautenbach Susan E. Coffin Sarah Tabbutt J William Gaynor Louis M. Bell | 2005 | The Pediatric Infectious Disease Journal2005，，4： | 1 |
| 10 | Clinical, biological, and histologic parameters as predictors of relapse in ulcerative colitis显示文摘 | Alain Bitton Mark A. Peppercorn Donald A. Antonioli John L. Niles Samir Shah Athos Bousvaros Bernard Ransil Gary Wild Albert Cohen Michael D. deB Edwardes Anthony C. Stevens | 2001 | Gastroenterology2001，，1： | 1 |
| 11 | Effects of statin therapy on the progression of chronic kidney disease显示文摘 | Samir Shah James Paparello Farhad R. Danesh | 2005 | Advances in Chronic Kidney Disease2005，，2： | 1 |
| 12 | Steatosis Is an Independent Predictor of Relapse Following Rapid Virologic Response in Patients With HCV Genotype 3显示文摘 | Samir R. Shah Keyur Patel Patrick Marcellin Graham R. Foster Michael Manns Shyam Kottilil Letha Healey Erik Pulkstenis G. Mani Subramanian John G. McHutchison Mark S. Sulkowski Stefan Zeuzem David R. Nelson | 2011 | Clinical Gastroenterology and Hepatology2011，，8： | 1 |
| 13 | Association of Serum Bilirubin with Ischemic Stroke Outcomes显示文摘 | Sandra Pineda Oh Young Bang Jeffrey L. Saver Sidney Starkman Susan W. Yun David S. Liebeskind Doojin Kim Latisha K. Ali Samir H. Shah Bruce Ovbiagele | 2008 | Journal of Stroke and Cerebrovascular Diseases2008，，3： | 1 |
| 14 | SCH 503034, a Novel Hepatitis C Virus Protease Inhibitor, Plus Pegylated Interferon α-2b for Genotype 1 Nonresponders显示文摘 | Christoph Sarrazin Regine Rouzier Frank Wagner Nicole Forestier Dominique Larrey Samir K. Gupta Musaddeq Hussain Amrik Shah David Cutler Jenny Zhang Stefan Zeuzem | 2007 | Gastroenterology2007，，4： | 1 |
| 15 | Clinical, biological, and histologic parameters as predictors of relapse in ulcerative colitis显示文摘 | Alain Bitton Mark A. Peppercorn Donald A. Antonioli John L. Niles Samir Shah Athos Bousvaros Bernard Ransil Gary Wild Albert Cohen Michael D. deB Edwardes Anthony C. Stevens | 2001 | Gastroenterology2001，，1： | 1 |
| 16 | A MULTI-INSTITUTIONAL, 5-YEAR ANALYSIS OF INITIAL AND MULTIPLE VENTRICULAR SHUNT REVISIONS IN CHILDREN显示文摘 | Jay G. Berry Matthew A. Hall Vidya Sharma Liliana Goumnerova Anthony D. Slonim Samir S. Shah | 2008 | Neurosurgery2008，，2： | 1 |
| 17 | Liver Transplantation: East versus West显示文摘 | Akash Shukla Hemant Vadeyar Mohamed Rela Samir Shah | 2013 | Journal of Clinical and Experimental Hepatology2013，，3： | 1 |
| 18 | An overview of nontradition- al formulations of static and dynamic equilibrium network design 显示文摘 | T L Friesz Samir Shah | 2001 | Transportantion Research: Part B2001，35，3： | 1 |
| 19 | Variation in Prevalence, Diagnostic Criteria, and Initial Management Options for Eosinophilic Gastrointestinal Diseases in the United States显示文摘 | Jonathan M Spergel Wendy M Book Elizabeth Mays Lihal Song Samir S Shah Nicholas J Talley Peter A Bonis | 2011 | Journal of Pediatric Gastroenterology and Nutrition2011，，： | 1 |
| 20 | Sigmoid Volvulus in Three College-Age Teenagers显示文摘 | Mark Slidell Samir A Shah Edward R | 2004 | J Clin Gastroenterol2004，38，10： | 1 |
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