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| 1 | 中国劳动力市场上工资收入的户籍歧视显示文摘20世纪80年代以来中国城镇劳动力市场上的农民工数量剧增,然而农民工却长期遭受着方方面面的歧视。其中一个突出表现是农民工和城镇职工之间明显的收入差距。但是,收入差距在多大程度上来源于歧视,学者们的观点并不一致。本文以2007年CHIPs(中国居民家庭收入调查)数据为基础,使用4种方法分解农民工和城镇职工的工资差异,考察劳动力市场上的歧视程度,重点突出指数基准问题对分解结果的影响。本文的实证分析结果显示2007年中国劳动力市场上依然存在对农民工明显的工资待遇歧视,农民工和城镇职工工资差异中的36%无法用禀赋差异解释。本文还强调工资收入歧视并不是检验户籍歧视的唯一指标,准确判断户籍歧视需要更广阔的视角。 | 章莉 李实 William A.Darity Jr. Rhonda Vonshay Sharpe | 2014 | 管理世界2014，30，11： | 111 |
| 2 | 中国劳动力市场就业机会的户籍歧视及其变化趋势显示文摘文章首先厘清了劳动力市场分割理论与歧视经济学的区别和联系,并将中国劳动力市场上就业机会的户籍不平等现象界定为以农民工平等就业权利受侵害为本质的经济歧视。其次,使用中国家庭收入调查(CHIP)2002年和2007年数据,运用多元logit模型考察了中国劳动力市场上就业机会的户籍歧视状况和变化趋势。实证分析结果显示:(1)与城镇职工相比,农民工在职业获得、行业进入和所有制部门进入三个维度上都遭受了明显的户籍歧视;(2)与2002年相比,2007年就业机会的户籍歧视呈现恶化趋势,显示了经济发展过程中就业机会分配的'负滴漏效应';(3)农民工人力资本的就业机会回报显著低于城镇职工,这对农民工的人力资本投资决策可能会产生负向激励并导致'前市场歧视'的发生。最后,在理论和实证分析的基础上,文章提出了缓解就业机会户籍歧视的相关政策建议。 | 章莉 李实 William A.Darity Jr. Rhonda Vonshay Sharpe | 2016 | 财经研究2016，42，1： | 57 |
| 3 | Iron and liver fibrosis: Mechanistic and clinical aspects显示文摘Liver fibrosis is characterised by excessive deposition of extracellular matrix that interrupts normal liver functionality. It is a pathological stage in several untreated chronic liver diseases such as the iron overload syndrome hereditary haemochromatosis, viral hepatitis, alcoholic liver disease, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis and diabetes. Interestingly, regardless of the aetiology, iron-loading is frequently observed in chronic liver diseases. Excess iron can feed the Fenton reaction to generate unquenchable amounts of free radicals that cause grave cellular and tissue damage and thereby contribute to fibrosis. Moreover, excess iron can induce fibrosis-promoting signals in the parenchymal and non-parenchymal cells, which accelerate disease progression and exacerbate liver pathology. Fibrosis regression is achievable following treatment, but if untreated or unsuccessful, it can progress to the irreversible cirrhotic stage leading to organ failure and hepatocellular carcinoma, where resection or transplantation remain the only curative options. Therefore,understanding the role of iron in liver fibrosis is extremely essential as it can help in formulating iron-related diagnostic, prognostic and treatment strategies. These can be implemented in isolation or in combination with the current approaches to prepone detection, and halt or decelerate fibrosis progression before it reaches the irreparable stage. Thus, this review narrates the role of iron in liver fibrosis. It examines the underlying mechanisms by which excess iron can facilitate fibrotic responses. It describes the role of iron in various clinical pathologies and lastly,highlights the significance and potential of iron-related proteins in the diagnosis and therapeutics of liver fibrosis. | Kosha J Mehta Sebastien Je Farnaud Paul A Sharp | 2019 | World Journal of Gastroenterology2019，25，5： | 39 |
| 4 | 血管内超声去肾交感神经术治疗高血压:一项多中心,国际,单盲,随机,假手术对照试验显示文摘早期研究表明,基于射频的去肾交感神经术可降低中度高血压患者的血压。研究者研究了在没有使用抗高血压药物的情况下,使用血管内超声去。肾交感神经术是否会降低高血压患者的动态血压。 | 刘青 叶鹏 Azizi M Schmieder RE Mahfoud F Weber MA Daemen J Davies J Basile J Kirtane AJ Wang Y Lobo MD Saxena M Feyz L Rader F Lurz P Sayer J Sapoval M Levy T Sanghvi K Abraham J Sharp ASP Fisher NDL Bloch MJ Reeve-Stoffer H Coleman L Mullin C Mauri L | 2018 | 中华高血压杂志2018，26，10： | 27 |
| 5 | 中国塔里木地块的视极移曲线显示文摘塔里木地块的视极移曲线由泥盆纪,晚石炭世,二叠纪,早三叠世和侏罗-白垩纪古地磁极联线构成。(D:P_(lat)=16,P_(long)=165,A_(95)=4;C_3:P_(lat)=41,P_(long)=160,A_(95)=4;P:P_(lat)=61,P_(long)=177,A_(95)=9;T_3:P_(lat)=69,P_(long)=183,A_(95)=11;J-K:P_(lat)=65,P_(long)=214,A_(95)=6)根据古地磁研究,塔里木地块在泥盆和二叠纪之间俯冲到哈萨克斯坦地块之下。塔里木,华北和华南的缝合年代在早三叠世和早白垩世之间,相对于西伯利亚,塔里木地块自白垩纪之后有较大的东向运动。 | 李燕平 李永安 张正坤 翟永健 李强 高振家 Robert Sharps Michael McWilliams | 1989 | 地质学报1989，63，3： | 13 |
| 6 | Factors influencing syphilis treatment failure and/or re-infection in HIV co-infected patients: immunosuppression or behaviors显示文摘背景最近的研究报导了有高度的梅毒的总的来说增加的率人的免疫不全评估病毒(HIV ) 合作感染。然而,几乎在 HIV 影响梅毒治疗失败或再感染的因素没有很少信息共同感染的病人。我们进行了研究评估在 HIV 与梅毒治疗 failure/re-infection 联系的因素到 2007 年 12 月的从 2005 年 1 月的感染 HIV 的病人的 3542 个医药记录列在后面在上面的我们考察了的共同感染的 patients.Methods 在在纽约的 HIV 诊所城市。病人们被快速的血浆分类重获 titer ( RPR )进 success/serofast (在到在治疗以后的 12 个月的 RPR 的4褶层减少, RPR 变换到没有4褶层增加的非电抗的、固执地稳定的反应 RPR ),并且 failure/re-infection (失败到在到在治疗以后的 12 个月的 RPR 的减少 4 褶层,从基线的 RPR 的4褶层增加)在满足了资格标准的 156 个病人的一个总数之中的 .Results ,( 78.2 ) 122 在 success/serofast 范畴下面,并且( 21.8 ) 34 在 failure/r 下面高度活跃的 antiretroviral 治疗(HAART ) 的 HIV 病毒的负担, CD4 房间计数,和使用没与梅毒治疗 failure/re-infection 被联系。然而,早梅毒舞台(OR:11.036, 95 CI:2.499-48.740, P=0.002 ) 并且高度(164 ) RPR titers (或:715.921, 95 CI:422.175-23 113.396, P 0.001 ) 显著地 associated.Conclusions 没有关联与梅毒治疗失败或再感染与沮丧的有免疫力的州被看见。然而,有早阶段梅毒的协会建议危险心理性行为可以是最重要的带因素,强调对安全的性教育的需要。 | Jong Hun Kim George Psevdos Jr Jin Suh Victoria Sharp | 2011 | Chinese Medical Journal2011，，14： | 10 |
| 7 | 塔里木地块侏罗、白垩纪的古地磁显示文摘本文对塔里木地块西北缘库车、拜城一带中新生代剖面进行了古地磁研究。库车与拜城两剖面具有不同方向产状,经产状校正之后,均为同一方向,表明磁性是在第三系褶皱之前获得的。热退磁结果表明500℃之前为现代地磁场方向,解阻温度为675℃,说明磁性载体为赤铁矿。 古地磁结果表明,塔里木地块在晚侏罗—晚白垩世之间没有经历大规模的构造运动。有可能自晚白垩世之后相对西伯利亚地块向北东方向移动过。 | 张正坤 李永安 李强 翟永建 李燕平 Michael McWilliams Allan cox Robert sharps | 1989 | 地震地质1989，11，3： | 7 |
| 8 | 高氮分压对碳热还原/氮化法合成氮化硅的影响显示文摘碳热还原/氮化合成氮化硅在1450-1650℃、氮气分压700-1100kPa下进行。非晶二氧化硅与石墨粉末以n(C)/n(SiO2)=4.5比率混合、压片。样品中的氧、氮、碳含量通过LECO元素分析仪测得。反应物和生成物中各物质组成通过XRD定性分析。结果表明,通过增加氮气分压,氮化硅的稳定温度升高,二氧化硅的还原速率随着温度升高而变大。碳化硅的生成仍无法避免。与常压下的碳热还原/氮化反应一致,高压下的碳化硅和氮化硅的生成亦为连续反应。 | 万小涵 张广清 John Sharp Oleg Ostrovski 俞乐 | 2015 | 有色金属工程2015，5，4： | 5 |
| 9 | Systematic review and meta-analysis on the association of tuberculosis in Crohn's disease patients treated with tumor necrosis factor-α inhibitors(Anti-TNFα)显示文摘AIM To perform a meta-analysis on the risk of developing Mycobacterium tuberculosis(TB) infection in Crohn's disease(CD) patients treated with tumor necrosis factoralpha(TNFα) inhibitors.METHODS A meta-analysis of randomized, double-blind, placebocontrolled trials of TNFα inhibitors for treatment of CD in adults was conducted. Arcsine transformation of TB incidence was performed to estimate risk difference. A novel epidemiologically-based correction(EBC) enabling inclusions of studies reporting no TB infection cases in placebo and treatment groups was developed to estimate relative odds.RESULTS Twenty-three clinical trial studies were identified, including 5669 patients. Six TB infection cases were reported across 5 studies, all from patients receiving TNFα inhibitors. Eighteen studies reported no TB infection cases in placebo and TNFα inhibitor treatment arms. TB infection risk was significantly increased among patients receiving TNFα inhibitors, with a risk difference of 0.028(95%CI: 0.0011-0.055). The odds ratio was 4.85(95%CI: 1.02-22.99) with EBC and 5.85(95%CI: 1.13-30.38) without EBC.CONCLUSION The risk of TB infection is higher among CD patients receiving TNFα inhibitors. Understanding the immunopathogenesis of CD is crucial, since using TNFα inhibitors in these patients could favor mycobacterial infections, particularly Mycobacterium avium subspecies paratuberculosis, which ultimately could worsen their clinical condition. | Brent L Cao Ahmad Qasem Robert C Sharp Latifa S Abdelli Saleh A Naser | 2018 | World Journal of Gastroenterology2018，24，25： | 4 |
| 10 | Physical modeling and visualization of soil liquefaction under high confining stress显示文摘The mechanisms of seismically-induced liquefaction of granular soils under high confining stresses are still not fully understood. Evaluation of these mechanisms is generally based on extrapolation of observed behavior at shallow depths.Three centrifuge model tests were conducted at RPI's experimental facility to investigate the effects of confining stresses on the dynamic response ora deep horizontal deposit of saturated sand. Liquefaction was observed at high confining stresses in each of the tests. A system identification procedure was used to estimate the associated shear strain and stress time histories.These histories revealed a response marked by shear strength degradation and dilative patterns. The recorded accelerations and pore pressures were employed to generate visual animations of the models. These visualizations revealed a liquefaction front traveling downward and leading to large shear strains and isolation of upper soil layers. | Lenart González Tarek Abdoun Mourad Zeghal Vivian Kallou Michael K. Sharp | 2005 | Earthquake Engineering and Engineering Vibration2005，4，1： | 4 |
| 11 | 消融的冰川:加拿大班夫国家公园亚高山带鲍湖中持久性有机氯的主要来源显示文摘有机氯杀虫剂和多氯联苯(PCB)是环境中普遍而稳固的化合物。现已查明,由于它们从温暖的地区逐渐蒸发出来,并在较冷的地区凝聚下来,因而它们富集在寒冷的环境中。在本研究中,我们的结果是,消融的冰川供给阿尔伯达亚高山带湖泊中的有机氯输入量为50%~97%,而提供的水量为73%。对氚的分析结果表明,在夏季的中、晚期,至少10%的冰川消融物是在1950~1970年期间沉积下来的,这期间它受到有机氯更多的污染。这一发现表明,气候变暖可能会使消融的冰川成为日益增多的淡水污染物来源。由于有机物贫乏的冰川粘土对多氯联苯这样的疏水化合物的吸附能力有限,因此冰川水流带来的有机氯大多呈溶解状态。 | Jules M. Blais David W. Schindler Derek C. G. Muir Martin Sharp David Donald MelissaLafrenière Eric Braekevelt William M. J. Strachan 周立志 | 2001 | AMBIO-人类环境杂志2001，30，7： | 4 |
| 12 | 急性儿茶酚胺暴露引起可逆的无心脏细胞再生的心肌细胞损伤显示文摘儿茶酚胺增加心脏收缩力,但暴露于高浓度儿茶酚胺或长时间暴露可引起心脏损伤。最近的一项研究表明,小鼠单次皮下注射异丙肾上腺素(isoproterenol,ISO;200 mg/kg)导致急性心肌细胞死亡(8%-10%),但在1个月之内心脏完整修复。心脏再生是通过内源性原癌基因蛋白质cKit+心脏干细胞介导新的心肌细胞形成。 | 刘莉 叶鹏 Wallner M Duran JM Mohsin S Troupes CD Vanhoutte D Borghetti G Vagnozzi RJ Gross P Yu D Trappanese DM Kubo H Toib A Sharp TE Harper SC Volkert MA Starosta T Feldsott EA Berretta RM Wang T Barbe MF Molkentin JD Houser SR | 2016 | 中华高血压杂志2016，24，8： | 4 |
| 13 | Molecular mechanisms involved in intestinal iron absorption显示文摘铁是在人的食谱的必要踪迹金属由于它的要求在很多个新陈代谢的过程的角色。在食谱,铁在很多种不同形式是在场的,是通常描述了哈他们(从在动物织物的血色素和肌球素) 并且 non-haem 铁(包括氧化铁和盐,含铁锡和 lactoferrin ) 。这评论描述从食谱和它的版本协调铁的吸收进发行量的分子的机制。当铁运输小径的许多部件被阐明了时,很多个关键问题尚待被决定。在这个区域的未来工作将由饮食、体液的因素关于铁和它的规定的 transcellular 流动提供一幅更清楚的图画。 | Paul Sharp Surjit Kaila Srai | 2007 | World Journal of Gastroenterology2007，13，35： | 3 |
| 14 | Efficacy of selective laser trabeculoplasty following incisional glaucoma surgery显示文摘AIM: To evaluate the efficacy of selective laser trabeculoplasty(SLT) in glaucomatous eyes with previous incisional glaucoma surgery. METHODS: A retrospective cohort of eyes that underwent SLT at a single institution from 2013-2015 were followed for 1 y. Reduction in intraocular pressure(IOP) following SLT was evaluated in eyes with prior trabeculectomy with Ex Press mini shunt(Alcon, Ft Worth, TX, USA), Ahmed valve(New World Medical, Cucamonga, CA, USA), or combined phacoemulsification-trabeculectomy. A control group was included with eyes without prior surgery that underwent SLT. Success was defined as >20% drop in IOP from pre-SLT baseline. RESULTS: One-hundred and six eyes were included with 53 in both the prior glaucoma surgery(PGS) and no prior glaucoma surgery(NPGS) groups. Mean pre-SLT IOP was 19.2±4.3 and 20.6±6.0 mm Hg for PGS and NPGS groups, respectively(P=0.17). Both groups produced statistically significant IOP reductions at 1 and 6 mo(P<0.04). At 6 mo, mean IOP reduction reached 7.3% and 10.8% for the PGS and NPGS groups, respectively(P=0.42). Overall, 27.9% and 31.7% of eyes in PGS and NPGS groups met success criteria at 1 y(P=0.70). In the PGS group, eyes with baseline IOP ≥21 mm Hg had IOP reductions of 18.1%(P<0.001), 16.7%(P<0.01), and 8.4%(P=0.31) compared to eyes with baseline IOP <21 mm Hg who had IOP reductions of 2.3%(P=0.39), 3.4%(P=0.19), and 1.1%(P=0.72) at 1, 6 mo, and 1 y, respectively. CONCLUSION: SLT is efficacious in eyes with prior incisional glaucoma surgery and results in similar IOP reductions compared to eyes without PGS. A larger IOP reduction is observed following SLT in eyes with higher pre-SLT IOP. | Robert Allan Sharpe Leah L Kammerdiener David B.Williams Sudeep K.Das Matthew J.Nutaitis | 2018 | International Journal of Ophthalmology(English edition)2018，11，1： | 3 |
| 15 | Identification and imaging of soil and soil-pile deformation in the presence of liquefaction显示文摘A simple identification technique is developed to visualize the dynamic deformation mechanisms of centrifuge models of saturated soil and soil-pile systems using the measurements provided by sparsely distributed sensors. Cross-correlation analyses are employed first to assess the variation of shear wave velocity profile with time as soil experiences stiffness reduction and degradation during dynamic excitations. The corresponding time-dependent modal configurations are determined using the finite-element technique. These configurations are used along with recorded motions to evaluate optimal time histories of displacement and strain fields based on a spectral motion reconstruction. Visualizations of the response of infinite slope and soil-pile centrifuge models revealed salient and complex multi-dimensional deformation patterns, especially at high pore pressure ratios. The developed technique provides an effective tool to visualize and analyze the dynamic response of centrifuge, shake-table and field soil systems. | M. Zeghal P. V. Kallou C. Oskay T. Abdoun M. K. Sharp | 2006 | Earthquake Engineering and Engineering Vibration2006，5，2： | 3 |
| 16 | RNAi:double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals显示文摘 | Zamore PD Tuschl T Sharp PA | 2000 | Cell2000，101，1： | 2 |
| 17 | The role of internationalization in explaining innovation performance显示文摘 | Mario I. Kafouros Peter J. Buckley John A. Sharp Chengqi Wang | 2007 | Technovation2007，，1： | 2 |
| 18 | Stereotactic body radiation therapy for management of spinal metastases in patients without spinal cord compression: a phase 1–2 trial显示文摘 | Xin Shelley Wang Laurence D Rhines Almon S Shiu James N Yang Ugur Selek Ibrahima Gning Ping Liu Pamela K Allen Syed S Azeem Paul D Brown Hadley J Sharp David C Weksberg Charles S Cleeland Eric L Chang | 2012 | Lancet Oncology2012，，4： | 2 |
| 19 | The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate显示文摘 | Patrick S. Ward Jay Patel David R. Wise Omar Abdel-Wahab Bryson D. Bennett Hilary A. Coller Justin R. Cross Valeria R. Fantin Cyrus V. Hedvat Alexander E. Perl Joshua D. Rabinowitz Martin Carroll Shinsan M. Su Kim A. Sharp Ross L. Levine Craig B. Thompson | 2010 | Cancer Cell2010，，3： | 2 |
| 20 | Prognostic value of baseline FDG uptake on PET-CT in esophageal carcinoma显示文摘AIM: To evaluate the influence of baseline maximum standardized uptake value(SUVmax) on survival in a cohort of patients, undergoing positron emission tomography-computed tomography(PET-CT) scan for esophageal carcinoma. METHODS: The pre-treatment SUVmax numeric reading was determined in patients with confirmed esophageal or junctional cancer having PET-CT scan during the time period 1st January 2007 until 31 st July 2012. A minimum follow up of 12 mo was required. Patients were subdivided into quartiles according to SUVmax value and the influence of SUVmax on survival was assessed using univariate and multivariate analysis. The following pre-treatment factors were investigated: patient characteristics, tumor characteristics and planned treatment. RESULTS: The study population was 271 patients(191male) with esophageal or junctional carcinoma. The median age was 65 years(range 40-85) and histologic subtype was adenocarcinoma in 197 patients and squamous carcinoma in 74 patients. The treatment intent was radical in 182 and palliative in 89 patients. SUVmax was linked to histologic subtype(P = 0.008), tumor site(P = 0.01) and Union for International Cancer Control(UICC) stage(P < 0.001). On univariate analysis, prognosis was significantly associated with SUVmax(P = 0.001), T-stage(P < 0.001) and UICC stage(P < 0.001). On multivariate analysis, only T-stage and UICC stage remained significant. CONCLUSION: Pretreatment SUVmax was not a useful marker in isolation for determining prognosis of patients with esophageal carcinoma. | Omar S Al-Taan Amar Eltweri David Sharpe Peter M Rodgers Sukhbir S Ubhi David J Bowrey | 2014 | World Journal of Gastrointestinal Oncology2014，6，5： | 2 |
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