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| 1 | Factors influencing syphilis treatment failure and/or re-infection in HIV co-infected patients: immunosuppression or behaviors显示文摘背景最近的研究报导了有高度的梅毒的总的来说增加的率人的免疫不全评估病毒(HIV ) 合作感染。然而,几乎在 HIV 影响梅毒治疗失败或再感染的因素没有很少信息共同感染的病人。我们进行了研究评估在 HIV 与梅毒治疗 failure/re-infection 联系的因素到 2007 年 12 月的从 2005 年 1 月的感染 HIV 的病人的 3542 个医药记录列在后面在上面的我们考察了的共同感染的 patients.Methods 在在纽约的 HIV 诊所城市。病人们被快速的血浆分类重获 titer ( RPR )进 success/serofast (在到在治疗以后的 12 个月的 RPR 的4褶层减少, RPR 变换到没有4褶层增加的非电抗的、固执地稳定的反应 RPR ),并且 failure/re-infection (失败到在到在治疗以后的 12 个月的 RPR 的减少 4 褶层,从基线的 RPR 的4褶层增加)在满足了资格标准的 156 个病人的一个总数之中的 .Results ,( 78.2 ) 122 在 success/serofast 范畴下面,并且( 21.8 ) 34 在 failure/r 下面高度活跃的 antiretroviral 治疗(HAART ) 的 HIV 病毒的负担, CD4 房间计数,和使用没与梅毒治疗 failure/re-infection 被联系。然而,早梅毒舞台(OR:11.036, 95 CI:2.499-48.740, P=0.002 ) 并且高度(164 ) RPR titers (或:715.921, 95 CI:422.175-23 113.396, P 0.001 ) 显著地 associated.Conclusions 没有关联与梅毒治疗失败或再感染与沮丧的有免疫力的州被看见。然而,有早阶段梅毒的协会建议危险心理性行为可以是最重要的带因素,强调对安全的性教育的需要。 | Jong Hun Kim George Psevdos Jr Jin Suh Victoria Sharp | 2011 | Chinese Medical Journal2011,,14: | 10 |
| 2 | Provider–Patient Communication About Adherence to Anti-retroviral Regimens Differs by Patient Race and Ethnicity显示文摘 | M. Barton Laws Yoojin Lee William H. Rogers Mary Catherine Beach Somnath Saha P. Todd Korthuis Victoria Sharp Jonathan Cohn Richard Moore Ira B. Wilson | 2014 | AIDS and Behavior2014,,7: | 1 |
| 3 | Co-infection of hepatitis B and hepatitis C virus in human immunodeficiency virus-infected patients in New York City,United States显示文摘瞄准:为了学习流行和风险因素,与人的免疫不全与三倍的感染联系了在一张城市的诊所人口的病毒(HIV )/hepatitis B (HBV )/hepatitis C 病毒(HCV ) 。方法:5639 个病人的回顾的图表评论在纽约城市里在圣卢凯斯鲁塞韦尔特医院 HIV 诊所(全面照顾的中心) 列在后面,从 1999 年 1 月的美国到 2007 年 5 月。下列人口统计的特征被分析:年龄,性别,种族和 HIV 冒因素的风险。多重逻辑回归分析被执行在这些病毒的获得上评估人口统计的因素的影响。结果:HIV/HBV, HIV/HCV 和 HIV/HBV/HCV 感染在 252/5639 (4.47%) 被检测, 1411/5639 (25.02%) 和 89/5639 (1.58%) 病人分别地。HIV/HBV 合作感染与男性被联系(或 1.711;P = 0.005 ) ,黑色跑(或 2.091;P <
0.001 ) ,人与 \O 性交人(MSM )( 或 1.747;P = 0.001 ) ,静脉内的药使用(IDU )( 或 0.114;P <
0.001 ) , IDU 和异性爱的活动(或 0.247;P = 0.018 ) ,或未知(或 1.984;P = 0.004 ) 。HIV/HCV 合作感染与男性被联系(或 1.241;P = 0.011 ) ,黑色跑(或 0.788;P = 0.036 ) , MSM (或 0.565;P <
0.001 ) , IDU (或 8.956;P <
0.001 ) , IDU 和异性爱的活动(或 9.106;P <
0.001 ) , IDU 和 MSM (或 9.179;P <
0.001 ) ,或输送(或 3.224;P <
0.001 ) 。HIV/HBV/HCV 合作感染与男性被联系(或 2.156;P = 0.015 ) , IDU (或 6.345;P <
0.001 ) , IDU 和异性爱的活动(或 9.731;P <
0.001 ) , IDU 和 MSM (或 9.228;P <
0.001 ) ,或未知(或 4.219;P = 0.007 ) 。结论:我们的学习证明有 HBV/HCV/HIV 的合作感染显著地与 IDU 被联系。这些结果加亮需要加强教育和综合照顾的最佳的模型,特别地为有 IDU 的人口,到减少病毒的传播的风险。 | Jong Hun Kim George Psevdos Jr Jin Suh Victoria Lee Sharp | 2008 | World Journal of Gastroenterology2008,14,43: | 1 |
| 4 | Predictors of loss of hepatitis B surface antigen in HIV-infected patients显示文摘AIM:To study factors associated with loss of hepatitis B surface antigen (HBsAg) in patients co-infected with human immunodeficiency virus (HIV) and hepatitis B virus (HBV).METHODS:We retrospectively reviewed the medical records of 5681 patients followed up at two New York City HIV clinics from January 1999 to May 2007.Clinical and laboratory parameters including baseline and follow-up HIV viral loads,CD4 cell counts,alanine transaminase levels,demographics,presence of hepatitis C infection,and treatment with highly active antiretroviral therapy dually active against both HIV and HBV infection,were analyzed to determine factors associated with loss of HBsAg.RESULTS:Three hundred and fifty five patients (355/5681,6.84%) were co-infected with HIV and HBV and were evaluated.Of these,226 patients with more than 12 mo follow-up were included in further analysis to determine factors associated with loss of HBsAg in the long-term follow-up.In the univariate analysis,baseline CD4 cell count was associated with loss of HBsAg (P=0.052).Cox regression analysis revealed that loss of HBsAg was associated with baseline CD4 cell count > 500 cells/mm3 (P=0.016,odds ratio:76.174,95% confidence interval:2.233-2598.481).CONCLUSION:Our study showed an interesting association of loss of HBsAg in HIV-HBV co-infected patients with higher CD4 cell count,suggesting that T-cell cytolytic activity against HBV may still be effective in clearing HBV infection. | George Psevdos Jong Hun Kim Jin S Suh Victoria Lee Sharp | 2010 | World Journal of Gastroenterology2010,16,9: | 0 |