|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | The incidence of Mirizzi syndrome in patients undergoing endoscopic retrograde cholangiopancreatography显示文摘BACKGROUND:Mirizzi syndrome is a rare complication of cholelithiasis,characterized by the narrowing of the common hepatic duct as a result of mechanical compression and/or inflammation due to biliary calculus impacted in the infundibula of the gallbladder or in the cystic duct.In this study,we aimed to describe the clinical presentations,investigations,operative details,and complications of seven patients who underwent endoscopic retrograde cholangiopancreatography and were finally diagnosed with Mirizzi syndrome in our center. METHOD:We performed a retrospective analysis of the records of 7 patients with Mirizzi syndrome who underwent endoscopic retrograde cholangiopancreatography. RESULTS:The incidence of Mirizzi syndrome was 1.07% of 656 patients given endoscopic retrograde cholangiopan- creatography.Ultrasonography was able to diagnose one case.Endoscopic retrograde cholangiopancreatography suggested the diagnosis in five cases and helped further in the management of these patients.Four patients had cholecystectomy and T-tube placement,and two had cholecystectomy and choledochoduodenostomy.One patient with typeⅠMirizzi syndrome according to the Csendes classification successfully underwent laparoscopic cholecystectomy. CONCLUSIONS:In the study,the incidence of Mirizzi syndrome was 1.07%of patients who underwent endoscopic retrograde cholangiopancreatography. Preoperative diagnosis of Mirizzi syndrome by endoscopicretrograde cholangiopancreatography is important to prevent complications. | Nadir Yonetci Ufuk Kutluana Mustafa Yilmaz Ugur Sungurtekin Koray Tekin | 2008 | Hepatobiliary & Pancreatic Diseases International2008，7，5： | 30 |
| 2 | Endoscopic submucosal dissection for premalignant lesions and noninvasive early gastrointestinal cancers显示文摘AIM: To investigate the indication, feasibility, safety, and clinical utility of endoscopic submucosal dissection (ESD) in the management of various gastrointestinal pathologies. METHODS: The medical records of 60 consecutive patients (34 female, 26 male) who underwent ESD at the gastroenterology department of Kocaeli University from 2006-2010 were examined. Patients selected for ESDhad premalignant lesions or non-invasive early cancers of the gastrointestinal tract and had endoscopic and histological diagnoses. Early cancers were considered to be confined to the submucosa, with no lymph node involvement by means of computed tomography and endosonography. RESULTS: Sixty ESD procedures were performed. The indications were epithelial lesions (n = 39) (33/39 adenoma with high grade dysplasia, 6/39 adenoma with low grade dysplasia), neuroendocrine tumor (n = 7), cancer (n = 7) (5/7 early colorectal cancer, 2/7 early gastric cancer), granular cell tumor (n = 3), gastrointestinal stromal tumor (n = 2), and leiomyoma (n = 2). En bloc and piecemeal resection rates were 91.6% (55/60) and 8.3% (5/60), respectively. Complete and incomplete resection rates were 96.6% (58/60) and 3.3% (2/60), respectively. Complications were major bleeding [n = 3 (5%)] and perforations [n = 5 (8.3%)] (4 colon, 1 stomach). Two patients with colonic perforations and two patients with submucosal lymphatic and microvasculature invasion (1 gastric carcinoid tumor, 1 colonic adenocarcinoma) were referred to surgery. During a mean follow-up of 12 mo, 1 patient with adenoma with high grade dysplasia underwent a second ESD procedure to resect a local recurrence. CONCLUSION: ESD is a feasible and safe method for treatment of premalignant lesions and early malignant gastrointestinal epithelial and subepithelial lesions. Successful en bloc and complete resection of lesions yield high cure rates with low recurrence. | Sadettin Hulagu Omer Senturk Cem Aygun Orhan Kocaman Altay Celebi Tolga Konduk Deniz Koc Goktug Sirin Ugur Korkmaz Ali Erkan Duman Neslihan Bozkurt Gokhan Dindar Tan Attila Yesim Gurbuz Orhan TarcinDivision of Gastroenterology Derince State Hospital Kocaeli 41900 Turkey Cem Kalayci | 2011 | World Journal of Gastroenterology2011，17，13： | 23 |
| 3 | Cetuximab plus FOLFOX6 or FOLFIRI in metastatic colorectal cancer: CECOG trial显示文摘AIM: To investigate efficacy and safety of cetuximab combined with two chemotherapy regimens in patients with unresectable metastatic colorectal cancer (mCRC). METHODS: Randomized patients received cetuximab with 5-fluorouracil (5-FU), folinic acid (FA) and oxaliplatin (FOLFOX) 6 (arm A, n = 74) or 5-FU, FA and irinotecan (FOLFIRI) (arm B, n = 77). KRAS mutation status was determined retrospectively in a subset of tumors (n = 117). RESULTS: No significant difference was found between treatment arms A and B in the progression-free survival (PFS) rate at 9 mo, 45% vs 34%; median PFS, 8.6 mo vs 8.3 mo [hazard ratio (HR) = 1.06]; overall response rate (ORR) 43% vs 45% [odds ratio (OR) = 0.93] and median overall survival (OS), 17.4 mo vs 18.9 mo (HR = 0.98). Patients with KRAS wild-type tumors demonstrated improved PFS (HR = 0.55, P = 0.0051), OS, (HR = 0.62, P = 0.0296) and ORR (53% vs 36%) and in arm A, improved PFS (HR = 0.49, P = 0.0196), OS (HR = 0.48, P = 0.0201) and ORR (56%vs 30%), compared with patients with KRAS mutated tumors. In arm B no significant differences were found in efficacy by KRAS mutation status. Treatment in arms A and B was generally well tolerated. CONCLUSION: This study confirms that combinations of cetuximab with FOLFOX6 or FOLFIRI are effective and significantly improve clinical outcome in KRAS wild-type compared with KRAS mutated mCRC. | Janja Ocvirk Thomas Brodowicz Fritz Wrba Tudor E Ciuleanu Galina Kurteva Semir Beslija Ivan Koza Zsuzsanna Pápai Diethelm Messinger Ugur Yilmaz Zsolt Faluhelyi Suayib Yalcin Demetris Papamichael Miklós Wenczl Zrinka Mrsic-Krmpotic Einat Shacham-Shmueli Damir Vrbanec Regina Esser Werner Scheithauer Christoph C Zie-linski | 2010 | World Journal of Gastroenterology2010，16，25： | 17 |
| 4 | Periodontopathogen profile of healthy and oral lichen planus patients with gingivitis or periodontitis显示文摘Oral lichen planus (OLP) is a chronic inflammatory disease that is frequently detected in oral tissues. The aim of our study was to identify the prevalence of the detection of periodontopathogenic microorganisms (Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, Tannerella forsythia and Treponema denticola in OLP patients and to compare with this prevalence of periodontopathogenic microorganisms in healthy non-OLP patients. Our study included 27 (18 chronic periodontitis (OLPP) and 9 gingivitis (OLPG)) patients diagnosed with OLP along with 26 (13 chronic periodontitis (HP) and 13 gingivitis (HG)) healthy non-OLP patients. The multiplex polymerase chain reaction (PCR) with subsequent reverse hybridization method (micro-IDent) was used for identifying periodontopathogenic microorganisms present in subgingival plaque samples. The percentages of detection for A. actinomycetemcomitans, P. gingivalis, P. intermedia, T. forsythia and T. denticola in subgingival plaque samples taken from OLP patients (OLPG and OLPP) were 18.5%, 85.1%, 81.4%, 88.8% and 74%, respectively. Meanwhile, in the non-OLP patients (HG and HP), these values were 7.6%, 50%, 46.1%, 73% and 57.7%, respectively. Thus, comparing the non-OLP groups with the OLP groups, the periodontopathogens' percentages of detection in the OLP groups were higher than those in the non-OLP groups. According to our study results, OLP patients have higher levels of infection with A. actinomycetemcomitans, P. gingivalis, P. intermedia, T. forsythia and T. denticola than non-OLP patients. We argue that the high percentages in patients with OLP may help identify the importance of periodontopathogenic microorganisms in the progress of periodontal diseases of OLP. | Abdullah Seckin Ertugrul Ugur Arslan Recep Dursun Sema Sezgin Hakki | 2013 | International Journal of Oral Science2013，5，2： | 15 |
| 5 | Effects of Helicobacter pylori infection on gastric epithelial cell kinetics in patients with chronic renal failure显示文摘AIM: To evaluate the effects of Helicobacter pylori infection on gastric epithelial cell kinetics in patients with chronic renal failure (CRF).METHODS: Forty-four patients were enrolled in this study and divided into four groups with respect to their Helicobacter pylori (H pylori) and CRF status. Groups were labeled as follows: 1a: normal renal function, H pylori negative (n = 12), 1b: normal renal function,H pylori positive (n = 11), 2a: CRF, H pylori negative (n = 10), 2b: CRF, H pylori positive (n = 11). Upper gastrointestinal endoscopy was done in all the patients involved in the study. During endoscopical investigation,antral biopsy specimens were taken from each patient.In order to evaluate the cell apoptosis and proliferation in gastric epithelial cells, Bax and proliferating cell nuclear antigen (PCNA) labeling indexes (LI) were assessed with immunohistochemical staining method.RESULTS: For groups 1a, 1b, 2a, and 2b, mean Bax LI was identified as 34.4±13.7, 44.1±16.5, 46.3±20.5,60.7±13.8, respectively and mean PCNA LI was identified as 36.2±17.2, 53.6±25.6, 59.5±25.6, 67.2±22,respectively. When the one-way ANOVA test was applied,statistically significant differences were detected between the groups for both Bax LI (P = 0.004 <0.01) and PCNA LI (P = 0.009 <0.01). When groups were compared further in terms of Bax LI and PCNA LI with Tukey's HSD test for multiple pairwise comparisons, statistically significant difference was observed only between groups 1a and 2b (P = 0.006 <0.01).CONCLUSION: In gastric epithelial cells, expression of both the pre-apoptotic protein Bax and the proliferation marker PCNA increase with H pylori infection. This increase is more evident in patients with uremia. These findings suggest that uremia accelerates apoptosis and proliferation in gastric epithelial cells. | Selim Aydemir Binnaz Handan Ozdemir Gurden Gur Ibrahim Dogan Ugur Yilmaz Sedat Boyacioglu | 2005 | World Journal of Gastroenterology2005，11，45： | 11 |
| 6 | Lipoma within inverted Meckel’s diverticulum as a cause of recurrent partial intestinal obstruction and hemorrhage: A case report and review of literature显示文摘Lipoma within an inverted Meckel's diverticulum presen- ting with hemorrhage and partial intestinal obstruction is an exceptional clinical entity. We report a case of 47-year-old male with a history of recurrent episodes of partial intestinal obstruction and melena due to a subserosal lipoma located in the base of an inverted Meckel's diverticulum. According to our knowledge, this is the first case of a lipoma within a Meckel's diverticulum giving rise to this clinical scenario without the existence of heterotrophic gastric or pancreatic tissues. | Güldeniz Karadeniz Cakmak Ali Ugur Emre Oge Tascilar Sibel Bekta■ Bulent Hamdi Uan Oktay Irkorucu Kemal Karakaya Yucel Ustundag Mustafa Comert | 2007 | World Journal of Gastroenterology2007，13，7： | 11 |
| 7 | SOME INEQUALITIES OF HERMITE-HADAMARD TYPE FOR s-CONVEX FUNCTIONS显示文摘In this paper several inequalities of the left-hand side of Hermite-Hadamard’s inequality are obtained for s-convex functions. | Mohammad W. Alomari Maslina Darus Ugur S. Kirmaci | 2011 | Acta Mathematica Scientia2011，31，4： | 9 |
| 8 | Protective effects of erythropoietin against acute lung injury in a rat model of acute necrotizing pancreatitis显示文摘瞄准:为了调查外长的 erythro-poietin (EPO ) 的效果,在钠 taurodeoxycholate- 的一个试验性的模型的尖锐的肺损害(ALI ) 上的管理导致了尖锐引起坏死胰腺炎(ANP ) 。方法:47 只男 Wistar 白鼠随机被划分成 7 个组:假冒的组(n = 5 ) , 3 个 ANP 组(n = 7 各个) 并且 3 个 EPO 组(n = 7 各个) 。ANP 被导致由后退进胆总管的 5% 钠 taurodeoxycholate 的注入。在 EPO 组的老鼠收到了 1000 U/kg 肌内的 EPO 立即在 ANP 的正式就职以后。在 ANP 组的老鼠相反被给 1 mL 生理盐水。所有动物被牺牲在手术后 24 h, 48 h 和 72 h。浆液 amilase, IL-2, IL-6 和肺织物 malondialdehyde (MDA ) 被测量。胸膜渗漏体积和肺 / 身体重量(LW/BW ) 比率是计算的。TNF-alpha, IL-2 和 IL-6 的织物层次组织化学地是屏蔽免疫。另外, ox-LDL 累积与免疫者荧光灯的染色被估计。在肺的组织病理学说的改变也被获得。结果:吝啬的胸膜渗漏体积,计算 LW/BW 比率,浆液 IL-6 和肺织物 MDA 层次比在 ANP 组在 EPO 组是显著地更低的。不,统计上,有效差量在这些组之中在浆液或 IL-2 的织物价值被观察。当时, ox-LDL 的肿瘤坏死 factor-alpha (TNF-alpha ) 和 IL-6 和累积的水平在 ANP 组的肺纸巾是明显的与 EPO 组相比,特别地在 72 h。组织病理学说的评估在外长的 EPO 管理以后在肺损害参数证实了改进,特别地在 48 h 和 72 h。结论:EPO 管理由禁止 polymorphonuclear (PMNL ) 在 ALI 参数导致重要减少累积,减少专业版的层次在每氧化的循环,保存微脉管的内皮房间正直和减少的氧化联系压力的类脂化合物的煽动性的 cytokines 并且因此,能在导致 ANP 的 ALI 被认为是一个 cytoprotective 代理人。 | Oge Tascilar Güldeniz Karadeniz Cakmak Ishak Ozel Tekin Ali Ugur Emre Bulent Hamdi Ucan Burak Bahadir Serefden Acikgoz Oktay Irkorucu Kemal Karakaya Hakan Balbaloglu Gürkan Kertis Handan Ankarali Mustafa Comert | 2007 | World Journal of Gastroenterology2007，13，46： | 8 |
| 9 | Percutaneous peritoneal drainage in isolated neonatal gastric perforation显示文摘A comment on the article by He et al, 'Idiopathic neonatal pneumoperitoneum with favorable outcome:A case report and review', published on World Journal of Gastroenterology that reported a case of idiopathic neonatal pneumoperitoneum, possibly due to gastric perforation, with a favorable outcome without surgical intervention. | Mustafa Aydin Ugur Deveci Erdal Taskin Unal Bakal Mehmet Kilic | 2015 | World Journal of Gastroenterology2015，21，45： | 8 |
| 10 | Appendiceal mucocele: Case reports and review of current literature显示文摘The mucocele of the appendix is an uncommon disorder which is often asymptomatic but sometimes causes acute appendicitis-like symptoms. Sometimes, patients with mucocele can present with confusing symptoms. Preoperative suspicion and diagnosis of appendiceal mucocele are important. Ultrasonography and computed tomography are useful tools for the diagnosis of appendiceal mucocele. It may be also recognised by colonoscopy as a smooth submucosal lesion of the cecum. Optima management of the mucocele could be achieved through accurate preoperative diagnosis. Preoperative diagnosis is a major component for minimizing intra-operative and post-operative complications. We herein report five cases and discuss the diagnostic methods and surgical treatment. | Kemal Karakaya Figen Barut Ali Ugur Emre Hamdi Bulent Ucan Guldeniz Karadeniz Cakmak Oktay Irkorucu Oge Tascilar Yucel Ustundag Mustafa Comert | 2008 | World Journal of Gastroenterology2008，14，14： | 8 |
| 11 | Usefulness of hounsfield unit and density in the assessment and treatment of urinary stones显示文摘Computed tomography(CT) is widely used to examine stones in the urinary system.In addition to the size and location of the stone and the overall health of the kidney,CT can also assess the density of the stone in Hounsfield units(HU).The HU,or Hounsfield density,measured by CT,is related to the density of the tissue or stone.A number of studies have assessed the use of HU in urology.HUs have been used to predict the type and opacity of stones during diagnosis,and the efficacy has been assessed using methods including extracorporeal shock wave lithotripsy(ESWL),percutaneous nephrolithotomy(PCNL),ureterorenoscopic ureterolithotripsy(URSL),and medical expulsive treatment(MET).Previous studies have focused on the success rate of HU for predicting the type of stone and of ESWL treatment.Understanding the composition of the stone plays a key role in determining the most appropriate treatment modality.The most recent reports have suggested that the HU value and its variants facilitate prediction of stone composition.However,the inclusion of data regarding urine,such as pH and presence of crystals,increases the predictive accuracy.HUs,which now form part of the clinical guidelines,allow us to predict the success of ESWL; therefore,they should be takeninto account when ESWL is considered as a treatment option.However,there are currently insufficient data available regarding the value of HU for assessing the efficacy of PCNL,URSL,and MET.Studies performed to date suggest that these values would make a significant contribution to the diagnosis and treatment of urinary system stones.However,more data are required to assess this further. | Adnan Gücük Ugur üyetürk | 2014 | World Journal of Nephrology2014，3，4： | 7 |
| 12 | Variation of vertical and horizontal drilling rates depending on some rock properties in the marble quarries显示文摘The main objective of this study is to determine the rates of vertically and horizontally oriented drilling processes in marble quarries and to observe the factors affecting the drilling rates in terms of physical and mechanical properties of the rocks. In situ drilling tests were performed in different marble quarries with different marble types and drilling times and penetration rates for a series of successive depthincrements were trying to be determined under vertically and horizontally oriented conditions. In order to understand the relation between the parameters that are investigated within the scope of this research, uniaxial compressive strength, Brazilian tensile strength, impact strength, Bohme abrasion strength, P-wave velocity, porosity, unit volume weight, Schmidt hardness index and brittleness index values were correlated with the drilling rates. It was noticed that the porosity and unit volume weight could be taken as the key parameters among them for obtaining meaningful correlation with drilling performance. It was also observed that the physical and mechanical rock properties are more relevant in vertical drilling than horizontal drilling. | Servet Demirdag Nazmi Sengun Ibrahim Ugur Tamer Efe Deniz Akbay Rasit Altindag | 2014 | International Journal of Mining Science and Technology2014，24，2： | 7 |
| 13 | Influences of 2.5wt%Mn addition on the microstructure and mechanical properties of Cu-Al-Ni shape memory alloys显示文摘微观结构和 Cu-11.9wt%Al-3.8wt%Ni 形状记忆 alloySMA 的机械性质上的 2.5wt%Mn 增加的影响借助于扫描电子 microscopySEM 被学习,传播电子 microscopyTEM ,并且微分扫描试验性的结果显示出的 calorimeterDSC.The Mn 增加更加在 Cu-Al-Ni alloy.The martensitic 转变影响奥氏体马氏体转变温度和马氏体的类型,这从 mixed111 | Ugur Sari | 2010 | International Journal of Minerals,Metallurgy and Materials2010，17，2： | 6 |
| 14 | Decreased paraoxonase1 activity and increased malondialdehyde and oxidative DNA damage levels in primary open angle glaucoma显示文摘To investigate the malondialdehyde(MDA) levels,paraoxonase1(PON1) activity and 8-hydroxy 2-deoxyguanosine(8-OHd G) levels in the primary open angle glaucoma(POAG) patient.Blood samples from 52 healthy individuals and 53 patients with POAG were analyzed for MDA and 8-OHd G by high-performance liquid chromatography(HPLC) and PON1 by spectrophotometry.The data obtained were analyzed statistically.MDA levels were 10.46±8.4 and 4.70±1.79 μmol; PON1 levels were 121 ±39.55 and 161.62 ±60.22 U/m L; and 8-OHd G values were1.32 ±0.53/10~6 d G and 0.47 ±0.27/10~6 d G in the POAG patients and the control group,respectively.The difference was significant in MDA levels,8-OHd G levels and PON1 activity in POAG patients in comparison with controls(P <0.001).We concluded that the observed increase in MDA and 8-OHd G levels may be correlated with decreased PON1 activity.Oxidative stress plays an important role in glaucoma development. | Ugur Yilmaz Mumcu Ibrahim Kocer Orhan Ates H.Hakan Alp | 2016 | International Journal of Ophthalmology(English edition)2016，9，10： | 6 |
| 15 | Efficacy and safety of pegylated-interferon α-2a in hemodialysis patients with chronic hepatitis C显示文摘AIM: To evaluate the efficacy and safety of pegylated-interferon alpha-2a in hemodialysis patients with chronichepatitis C.METHODS: Thirty-six hemodialysis patients with chronichepatitis C were enrolled in a controlled and prospectivestudy. All patients were treatment naive, positivetested for anti-HCV antibodies, and positive tested forserum HCV-RNA. Twenty-two patients received 135 μgpeglyated-interferon a-2a weekly for 48 wk (group A).The remaining patients were left untreated, elevenrefused therapy, and three were not candidates forkidney transplantation and were allocated to the controlgroup (group B). At the end of the treatment biochemicaland virological response was evaluated, and 24 wk aftercompletetion of therapy sustained virological response(SVR) was assessed. Side effects were monitored.RESULTS: Of 22 hemodialysis patients, 12 were maleand 10 female, with a mean age of 35.2 ± 12.1 years.Virological end-of-treatment response was observed in14 patients (82.4%) in group A and in one patient (7.1%)in group B (P = 0.001). Sustained virological responsewas observed in 11 patients (64.7%) in group A and inone patient in group B (7.1%). Biochemical responseparameters normalized in 10/14 patients (71.4%) at theend of the treatment. ALT levels in group B were initiallyhigh in six patients and normalized in one of them (25%)at the end of the 48 wk. In five patients (22.7%) therapyhad to be stopped at mo 4 due to complications ofweakness, anemia, and bleeding.CONCLUSION: SVR could be achieved in 64.7% ofpatients on hemodialysis with chronic hepatitis C by atreatment with peglyated-interferon a-2a. Group A hada significantly better efficacy compared to the controlgroup B, but the side effects need to be concerned. | Celal Ayaz Mustafa Kemal Celen Ugur Nedim Yuce Mehmet Faruk Geyik | 2008 | World Journal of Gastroenterology2008，14，2： | 5 |
| 16 | He/icobacter py/ori infection in hemodialysis patients: Susceptibility to amoxicillin and clarithromycin显示文摘AIM: To evaluate susceptibility of Helicobacter pylori to amoxicillin and clarithromycin in end-stage renal disease (ESRD) patients and non-uremic controls.METHODS: The subjects with dyspeptic complaints were 33 ESRD patients and 46 age- and sex-matched nonuremic controls who exhibited H pylori on antral biopsy specimens. The two groups were age and sex matched.The H pylori strains' pattern of susceptibility to amoxicillin and clarithromycin was investigated with the agar dilution technique.RESULTS: None of the H pylori strains from either group showed resistance to amoxicillin with the agar dilution method. Twelve (36.4%) of the ESRD group strains and 7 (15.2%) of the control group strains showed resistance to clarithromycin, and this difference was statistically significant (P<0.05).CONCLUSION: Resistance to amoxicillin does not appear to be an important problem in H pylori-infected ESRD and non-uremic patients in our region. In contrast, the rates of resistance to clarithromycin are high, particularly in the ESRD population. | Selim Aydemir Sedat Boyacioglu Gurden Gur Muge Demirbilek Fusun Kamber Can Murat Korkmaz Ugur Yilmaz | 2005 | World Journal of Gastroenterology2005，11，6： | 5 |
| 17 | Neuroprotective effects of daidzein on focal cerebral ischemia injury in rats显示文摘Daidzein, a plant extract, has antioxidant activity. It is hypothesized, in this study, that daidzein exhibits neuroprotective effects on cerebral ischemia. Rat models of middle cerebral artery occlusion were intraperitoneally administered daidzein. Biochemical and immunohistochemical tests showed that superoxide dismutase and nuclear respiratory factor 1 expression levels in the brain tissue decreased after ischemia and they increased obviously after daidzein administration; malondialdehyde level and apoptosis-related cysteine peptidase caspase-3 and caspase-9 immunoreactivity in the brain tissue increased after ischemia and they decreased obviously after daidzein administration. Hematoxylin-eosin staining and luxol fast blue staining results showed that intraperitoneal administration of daidzein markedly alleviated neuronal damage in the ischemic brain tissue. These findings suggest that daidzein exhibits neuroprotective effects on ischemic brain tissue by decreasing oxygen free radical production, which validates the aforementioned hypothesis. | Adem Bozkurt Aras Mustafa Guven Tar?k Akman Adile Ozkan Halil Murat Sen Ugur Duz Y?ld?ray Kalkan Coskun Silan Murat Cosar | 2015 | Neural Regeneration Research2015，10，1： | 4 |
| 18 | Low eradication rate of Helicobacterpyloriwith triple 7-14 days and quadriple therapy in Turkey显示文摘AIM:The eradication rate of Helicobacter pylori (H pylon) shows variation among countries and regimens of treatment.We aimed to study the eradication rates of different regimens in our region and some factors affecting the rate of eradication.METHODS:One hundred and sixty-four Hpylori positivepatients (68 males, 96 females; mean age:48±12 years)with duodenal or gastric ulcer without a smoking history were included in the study. The patients were divided into three groups according to the treatment regimens. Omeprazole 20mg, clarithromycin 500mg, amoxicillin 1g were given twice daily for 1 week (Group I) and 2 weeks (Group Ⅱ).Patients in Group Ⅲ received bismuth subsitrate 300mg,tetracyline 500 mg and metronidazole 500mg four times daily in addition to Omeprazole 20mg twice daily.Two biopsies each before and after treatment were obtained from antrum and corpus, and histopathologically evaluated.Eradication was assumed to be successful if no Hpylorus was detected from four biopsy specimens taken after treatment. The effects of factors like age, sex, Hpyloridensity on antrum and corpus before treatment, the total Hpylori density, and the inflammation scores on the rate of Hpylori eradication were evaluated.RESULTS:The overall eradication rate was 42%. The rates in groups Ⅱ and Ⅲ were statistically higher than that in group I (P<0.05). The rates of eradication were 24.5%,40.7% and 61.5% in groups Ⅰ, Ⅱ and Ⅲ, respectively. The eradication rate was negatively related to either corpus Hpylori density or total Hpyloridensity (P<0.05).The median age was older in the group in which the eradication failed in comparison to that with successful eradication (55yr vs 39yr, P<0.001). No correlation between sex and Hpylori eradication was found.CONCLUSION: Our rates of eradication were significantly lower when compared to those reported in literature.We believe that advanced age and high Hpyloridensity are negative predictive factors for the rate of Hpylorieradication. | Yuksel Gumurdulu Ender Serin Birol zer Fazilet Kayaselcuk Kursat Ozsahin Arif Mansur Cosar Murat Gursoy Gurden Gur Ugur Yilmaz Sedat Boyacioglu | 2004 | World Journal of Gastroenterology2004，10，5： | 4 |
| 19 | A Model Predictive Control for Microgrids Considering Battery Aging显示文摘The increasing number of distributed energy resources(DERs),advancing communication and computation technologies,and reliability concerns of the customers have caused an intense interest in the concept of microgrid.Although DERs are the biggest motivation of the microgrids due to their intermittent generation characteristics,they constitute a risk for system reliability.Battery storage systems(BSSs)stand as one of the most effective solutions for this reliability problem.However,the inappropriate use of BSS creates other operational problems in power systems.In order to deal with these concerns explicitly in microgrids,an optimized microgrid central controller(MGCC)is the key factor,which controls the realtime operation of a microgrid.This work proposes a model predictive control(MPC)based MGCC that will provide optimal control of the microgrid,considering economic and operational constraints.The proposed system will minimize the energy cost of the microgrid by utilizing mixed-integer linear programming(MILP)assuming the presence of DERs and BSS as well as the bi-directional grid connection.Moreover,the aging effect of BSS will be considered in the proposed optimization problem which will provide an up-to-date system model.The proposed method is evaluated using real load and photovoltaic(PV)generation data. | Ugur Can Yilmaz Mustafa Erdem Sezgin Murat Gol | 2020 | Journal of Modern Power Systems and Clean Energy2020，8，2： | 3 |
| 20 | Clinical and impression cytology findings of amniotic membrane and oral mucosal membrane transplantation for the management of socket contracture显示文摘AIM:To investigate and compare the cytopathological and clinical effects of amniotic membrane transplantation(AMT)and oral mucosal membrane transplantation(OMMT)in socket contraction.METHODS:Twelve patients who could not be fitted with ocular prosthesis due to socket contracture were included in this study.Seven patients underwent AMT and 5 patients underwent OMMT.Thirteen patients who had healthy sockets were included as control group.Depth of inferior fornix,degree of inflammation,extent of the socket contracture and socket volume were measured in the preoperative period and at sixth and twelfth weeks postoperatively.Impression cytology of conjunctival fornices and tear transforming growth factor beta-1(TGFβ1)levels were determined.RESULTS:In the AMT group,socket volume and lower fornix depth values were significantly higher(P=0.030and P=0.004 respectively)and inflammation levels and impression cytology stages(P=0.037 and P=0.022respectively)were significantly lower in postoperative period compared to preoperative period.In the OMMT group,no statistical differences were found in terms of clinical parameters,inflammation levels and impression cytology stages of preoperative versus postoperative values.Preoperative tear TGFβ1 levels were higher in AMT and OMMT groups compared to the control group(25.5 ng/mL,26.3 ng/mL and 21.7 ng/mL respectively).Decreased tear TGFβ1 levels were observed in both the AMT and OMMT groups postoperatively(median decrease value=2.1 ng/mL and 2.7 ng/mL respectively).CONCLUSION:AMT is associated with postoperative improvement in inferior fornix depth,socket volume,inflammation and impression cytology levels and may bea more proper alternative method than OMMT in the management of socket contracture. | Bengi Ece Kurtul Ugur Erdener Mehmet Cem Mocan Murat Irkec Mehmet Orhan | 2014 | International Journal of Ophthalmology(English edition)2014，7，2： | 3 |
您所在的机构暂未开通此部分的功能，请联系管理员