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199篇 您的检索式:作者名="Rowe S M"
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1最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL 2014神经病学与神经康复学杂志2014,11,3:31
2美国国立老化研究所与阿尔茨海默病协会诊断指南写作组:阿尔茨海默病临床前阶段的定义显示文摘阿尔茨海默病(AD)的病理生理过程在痴呆诊断的多年前就开始了。这一长期的AD“临床前”阶段是治疗干预的关键机会,但需进一步阐明AD的病理级联过程和临床症状出现之间的联系。美国国立老化研究所和AD协会召集了一个国际工作组对AD生物标志物、流行病学和神经心理学的证据进行综述并提出建议,以确定能够预测由“正常”认知到轻度认知功能障碍(MCI)及AD痴呆的最佳预测指标。根据目前已有的主要科学证据,我们提出了一个概念性的框架和用于操作的研究标准,以通过纵向临床研究来验证和改进这些模型。这些建议仅用于研究目的,目前不涉及临床应用。我们希望这些建议能提供一个共识,以推进临床前AD的研究,最终推动更早期治疗干预的进展,使得一些疾病减缓药物的疗效发挥最大。Sperling RA Aisen PS Beckett LA Bennett DA Craft S Fagan AM Iwatsubo T Jack CR Jr Kaye J Montine TJ Park DC Reiman EM Rowe CC Siemers E Stern Y Yaffe K Carrillo MC Thies B Morrison-Bogorad M Wagster MV Phelps CH 贾建平(译) 郭起浩(译) 黄丽(译) 陆璐(译) 张逸驰(译) 邢怡(译) 2012中华神经科杂志2012,45,5:22
3Oxidative environments decrease tenderization of beef steaks through inactivation of μ-ealpain显示文摘Rowe L J Maddock K P Lonergan S M 2004J Anita Sci2004,82,:1
4Viscosity-Elastic Analysis of Hot Mix Asphalt Pavement显示文摘Rowe B Sharrock S F Bouldin M J 1995Transportation Research Record1995,,1482:1
5Progress in cystic fibrosis and the CF Therapeutics Development Network 显示文摘Rowe S M Borowitz D S Burns J L ct al 2012Thorax2012,67,10:1
6Seeing red? Putting sportswear in context显示文摘ROWE C HARRIS J M ROBERTS S C 2005Nature2005,437,:1
7Value Orientations, Awareness of Consequences, and Participation in a Whale Watching Education Program in Oregon 显示文摘Christensen A Rowe S Needham M D 2007Human Dimensions of Wildlife2007,12,4:1
8Recent developments in underwater wet welding 显示文摘Rowe M Liu S 2001Science and Technology of Welding and Joining2001,6,6:1
9查看详情显示文摘Rowe D M Shukla V S Savvides N 0,,5809:1
10Early postmortem biochemical factors influence tenderness and water-holding capacity of three porcine muscles显示文摘MELODY J L LONERGAN S M ROWE L J 2004J Anita Sci2004,,82:1
11Synthesis of surface-initiated stimuli-responsive diblock eopolymer brushes utilizing a combination of ATRP and RAFT polymerization techniques显示文摘Rowe M A Hammer B A G Boyes S G 2008Macromolecules2008,41,12:1
12Is the current BMI obesity classification appropriate for black and white post- menopausal women? 显示文摘EVANS E M ROWE D A GACETTE S B etal 2006Int J Obes (Lond)2006,30,5:1
13The effect of deformation on the contact area in grinding 显示文摘ROWE W B MORGAN M N QI H S 1993CIRP Annals: Manufacturing Technology1993,42,1:1
14Recent developments in underwater wet welding 显示文摘Rowe M Liu S 2001Science and Technology of Welding and Joining2001,6,6:1
15MBE growth and properties of ZnO on sapphire and SiC substrates 显示文摘Johnson M A L Fujita S Row landW H J Electron Mater0,25,5:1
16Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death 显示文摘Henderson S Rowe M Gregory C 1991Cell1991,65,7:1
17Early postmortem biochemical factors influence tenderness and water-holding capacity of three porcine muscles显示文摘Melody J L Lonergan S M Rowe L J 2004Journal of Animal Science2004,82,:1
18Robust detection of stochastic nuclear quadrupole resonance signals 显示文摘SOMASUNDARAM S D JAKOBSSON A ROWE M D 2008IEEE Transactions on Signal Processing2008,56,9:1
19Serum 2-hydroxyglutarate levels predict isocitrate dehydrogenase mutations and clinical outcome in acute myeloid leukemia显示文摘DiNardo C D Propert K J Loren A W Paietta E Sun Z X Levine R L Straley K S Yen K Patel J P Agresta S Abdel-Wahab O Perl A E Litzow M R Rowe J M Lazarus H M Fernandez H F Margolis D J Tallman M S Luger S M Carroll M 2012Blood2012,121,24:1
20Solution combustion synthesis of g(L)-Bi2MoOs and photocatalytic activity under solar radiation 显示文摘Dipankar S Giridhar M Guru Row T N Mater 2011Resear Bulletin2011,46,:1
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