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| 1 | 区域创新系统的管治框架演化——来自深圳和东莞的对比实证显示文摘本文在电子企业问卷调查的基础上,对比分析深圳和东莞的区域创新机制,并进一步从管治角度构建区域创新机制差异的理论框架,在中国转型的体制背景下阐释管治的演化逻辑。结果显示,改革开放初期自上而下的管治模式相对于自下而上的管治,在各自向网络化管治模式演化的过程中,由于先发制度优势和组织能力禀赋,更能顺利的推动工业基础薄弱地区向区域创新系统的转变。最后指出,演化视角分析必须注重时间和地理的特殊性。 | 符文颖 Javier Revilla Diez Daniel Schiller | 2013 | 人文地理2013，28，4： | 8 |
| 2 | Gene expression changes in spleens of the wildlife reservoir species,Eurasian wild boar(Sus scrofa),naturally infected with Brucella suis biovar 2显示文摘Brucella suis is responsible for swine brucellosis worldwide.Of the five different B.suis biovars(bv.),bv.2 appears restricted to Europe where it is frequently isolated from wild boar and hares,can infect pigs and can cause human brucellosis.In this study,the differential gene expression profile was characterized in spleens of Eurasian wild boar naturally infected with B.suis bv.2.Of the 20,201 genes analyzed in the microarray,633 and 1,373 were significantly(fold change > 1.8;P < 0.01) upregulated and downregulated,respectively,in infected wild boar.The analysis was focused on genes that were over represented after conditional test for biological process gene ontology.Upregulated genes suggested that B.suis bv.2 infection induced cell maturation,migration and/or proliferation in infected animals.The genes downregulated in infected wild boar impaired the activity of several important cellular metabolic pathways such as metabolism,cytoskeleton organization and biogenesis,immune response and lysosomal function and vesicle-mediated transport.In addition,the response to stress,sperm fertility,muscle development and apoptosis seemed to be also impaired in infected animals.These results suggested that B.suis bv.2 may use strategies similar to other smooth brucellae to facilitate intracellular multiplication and the development of chronic infections.To our knowledge,this is the first report of the analysis of gene expression profile in hosts infected with B.suis bv.2,which is important to understand the molecular mechanisms at the host-pathogen interface in the main reservoir species with possible implications in the zoonotic cycle of the pathogen. | Ruth C.Galindo Pilar M.Muoz María J.de Miguel Clara M.Marin Javier Labairu Miguel Revilla José M.Blasco Christian Gortazar José de la Fuente | 2010 | Journal of Genetics and Genomics2010，37，11： | 6 |
| 3 | Aplastic anemia and severe pancytopenia during treatment with peg-interferon,ribavirin and telaprevir for chronic hepatitis C显示文摘Telaprevir and Boceprevir are the first direct acting antivirals approved for chronic hepatitis C in combination with peg-interferon alfa and ribavirin.Pancytopenia due to myelotoxicity caused by these drugs may occur,but severe hematological abnormalities or aplastic anemia(AA) have not been described.We collected all cases of severe pancytopenia observed during triple therapy with telaprevir in four Spanish centers since approval of the drug in 2011.Among 142 cirrhotic patients receiving treatment,7 cases of severe pancytopenia(5%) were identified and three were consistent with the diagnosis of AA.Mean age was 59 years,five patients had compensated cirrhosis and two patients had severe hepatitis C recurrence after liver transplantation.Severe pancytopenia was diagnosed a median of 10 wk after the initiation of therapy.Three patients had pre-treatment hematological abnormalities related to splenomegaly.In six patients,antiviral treatment was interrupted at the onset of hematological abnormalities.Two patients died due to septic complications and one patient due to acute alveolar hemorrhage.The remaining patients recovered.Severe pancytopenia and especially AA,are not rare during triple therapy with telaprevir in patients with advanced liver disease.Close monitoring is imperative in this setting to promptly detect serious hematological disorders and to prevent further complications. | Sabela Lens Jose L Calleja Ana Campillo Jose A Carrion Teresa Broquetas Christie Perello Juan de la Revilla Zoe Marino Maria-Carlota Londono Jose M Sanchez-Tapias Alvaro Urbano-Ispizua Xavier Forns | 2015 | World Journal of Gastroenterology2015，21，17： | 4 |
| 4 | Bone Marrow Mesenchymal Stem Cells Stimulate Cardiac Stem Cell Proliferation and Differentiation显示文摘 | Konstantinos E. Hatzistergos Henry Quevedo Behzad N. Oskouei Qinghua Hu Gary S. Feigenbaum Irene S. Margitich Ramesh Mazhari Andrew J. Boyle Juan P. Zambrano Jose E. Rodriguez Raul Dulce Pradip M. Pattany David Valdes Concepcion Revilla Alan W. Heldman Ia | 2010 | Circulation Research2010，，7： | 2 |
| 5 | Building dynamic capabilities in product de- velopment: How do contextual antecedents matter? 显示文摘 | Isabel M Prieto Elena Revilla Beatriz Rodr?' guez- Prado | 2009 | Scandinavian Journal of Management2009，25，： | 1 |
| 6 | The Dark Side of Buyer-Supplier Relationships: A Social Capital Perspective 显示文摘 | Villena V H Revilla E Choi T Y | 2011 | Journal of Operations Management2011，29，6： | 1 |
| 7 | Callus induction and a preliminary attempt to obtain cell suspensions from embryos and levels of Juglans regia L 显示文摘 | Rodriguez R Revilla M A Perez C | 1987 | Acta Hort (ISHS)1987，12，： | 1 |
| 8 | Contribution of autoch- thonous maize populations for adaptation to European con- ditions显示文摘 | Revilla P Boyat A lvarez A | 2006 | Euphytica2006，152，2： | 1 |
| 9 | Various applications of liquid chromatography-mass spectrometry to the analysis of phenolic compounds 显示文摘 | PEREZ-MAGARINO S REVILLA I BELTRAN S | 1999 | Chromatogr A1999，，847： | 1 |
| 10 | Anthocyanin composition of Cabernet Sauvignon and Tempranillo grapes at different stages of ripening显示文摘 | Revilla E | 2003 | J Agric Food Chem2003，51，： | 1 |
| 11 | Knowledge integration taxonomy in buyer-supplier relationships: Trade-offs between efficiency and innovation 显示文摘 | Revilla E and Villena V H | 2012 | International Journal of Production Eco-nomics2012，140，2： | 1 |
| 12 | Prognostic Significance of Uric Acid Serum Concentration in Patients With Acute Ischemic Stroke显示文摘 | ángel Chamorro Victor Obach álvaro Cervera Marian Revilla Ramón Deulofeu John H. Aponte | 2002 | Stroke: Journal of the American Heart Association2002，，： | 1 |
| 13 | Effect of locust bean/xanthan gum addition and replacement of pork fat with olive oil on the quality characteristicsof low-fat frankfurters显示文摘 | LURUENA-MARTINEZ M A VIVAR-QUINTANA A M REVILLA I | 2004 | Meat Science2004，68，3： | 1 |
| 14 | Insect damage to sweet corn hybrids in the south Atlantic European coast显示文摘 | Malvar R A Revilla P Velasco P | 2002 | Journal of American Society for Horticultural Science2002，127，： | 1 |
| 15 | Eutrophication Assessment in Basque Estuaries: Comparing a North American and a European Method显示文摘 | Maialen Garmendia Suzanne Bricker Marta Revilla ángel Borja Javier Franco Juan Bald Victoriano Valencia | 2012 | Estuaries and Coasts2012，，4： | 1 |
| 16 | Correlation of ultrasound bone velocity with dual energy X-ray bone absorptionmetry in rat bone specimens显示文摘 | Amo C Revilla M Hermandez ER | 1996 | Invest R adiol1996，31，2： | 1 |
| 17 | Potential of remote sensing techniques for tsunami hazard and vulnerability analysis – a case study from Phang-Nga province, Thailand显示文摘 | R?mer H. Willroth P. Kaiser G. Vafeidis A. T. Ludwig R. Sterr H. Revilla Diez J | 2012 | 2012 (159)2012，，159： | 1 |
| 18 | Analysis of several phenolic compounds with potential antioxidant properties in grape extracts and wines by high- performance liquid chromatography - photodiode array detection without sample preparation显示文摘 | Ryan J M | 2000 | J Chrom2000，，： | 1 |
| 19 | Identification of anthocyanin derivatives in grape skin extracts and red wines by liquid chromatography with diode array and mass spectrometric detection 显示文摘 | Revilla I Perez-Magarino S Gonzalez-SanJose ML | 1999 | Journal of Chromatography A1999，847，： | 1 |
| 20 | Nutraceutical composition, antioxidant activity and hypocholesterolemic effect of a water- soluble enzymatic extract from rice bran 显示文摘 | Revilla E Maria CS Miramontes E | 2009 | Food Research International2009，42，3： | 1 |
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