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| 1 | 虚拟货币及其扩展:初步思考显示文摘随着信息加密和网络计算机技术日趋成熟,科技正在推动全球经济的转型变革。虚拟货币的产生在此过程中又显得至关重要。虚拟货币方案在许多情况下便于对等网络交互绕过传统的中央结算所。虚拟货币及其关联技术(特别是基于区块链的分布式账本)正在迅速发展,其未来前景难以预测。虚拟货币带来了许多潜在益处,包括更快速、高效的支付和转账等,并将最终促进普惠金融。一些虚拟货币方案背后的分布式账本技术提供的潜在益处将远超虚拟货币本身。但是,虚拟货币的出现也引发了许多潜在风险,如成为洗钱、恐怖融资、偷税漏税和欺诈等犯罪的工具。虚拟货币虽然目前的规模仍非常有限,对现阶段货币政策实施产生的风险亦甚微,但随着新技术的广泛应用,其对金融稳定产生的影响会日益显现。有关虚拟货币的有效监管对策还处于起步阶段。虚拟货币的在国家层面跨越了不同机构的职责,并在全球范围内操作,其监管难度很大。并且,许多虚拟货币在传统金融系统之外运作,缺乏透明度,其操作过程更难以被监管。各国监管机构已开始着手应对这些挑战且方式各异。需要注意的是,国家主管部门需认真权衡监管方式,既要适当处置风险又不能扼杀创新。为了在国家层面推进发展进程和促进政策的完善,国际层面也应进行更多努力。随着经验的不断积累,可考虑提出国际标准和最优方法,为不同领域的最优监管对策提供指导,从而促进跨辖区的协调。也可在此类标准基础上,为一些领域设立跨国合作和协调的框架。 | 何东 卡尔·哈伯梅尔 罗斯·莱科 郭建伟 郇志坚 Vikram Haksar Yasmin Almeida Mikari Kashima Nadim Kyriakos-Saad Hiroko Oura Tahsin Saadi Sedik Natalia Stetsenko Concepcion Verdugo.Yepes | 2016 | 金融监管研究2016，，4： | 22 |
| 2 | 基于胜任力模型培养护士长领导力的效果研究显示文摘目的探讨基于胜任力模型培养护士长领导力的效果。方法选取22名护士长进行为期3年的岗位领导力培训,包括成立管理委员会、论证护士长领导力以及基于胜任力模型的沟通和关系管理、临床实践知识、职业水准、经营知识和技能等方面培训内容的构建,研究结束后,比较护士长培训前后的领导力及护士对护士长的满意度。结果培训后,护士长的领导力各维度得分提高,护士对护士长的满意度各条目得分均提高。结论以护理管理者胜任力模型为基础的护理管理培训和实践可以有效提升护士长的岗位胜任力。 | 侯艳 沈晓雁 张异凡 陈立新 邢广军 Chanell Carcallas Concepcion | 2018 | 护理管理杂志2018，18，10： | 20 |
| 3 | Direct conversion of human fibroblasts into retinal pigment epithelium-like cells by defined factors显示文摘功能的网膜的颜料上皮(RPE ) 的产生具有到再生药的地的大治疗学的兴趣并且可以为网膜的退化疾病提供可能的痊愈,包括年龄相关的有斑点的退化(AMD ) 。尽管 RPE 房间能从胚胎的干细胞被生产或导致了 pluripotent 干细胞,决定系的抄写因素驾驶的直接房间 reprogramming 提供一条立即的线路给他们的产生。由监视人的 RPE 特定的 Best1::GFP 记者,我们报导进 RPE 系使用的人的成纤维细胞的变换定义抄写因素的集合。我们发现 Best1::GFP 积极房间形成了殖民地并且展出了早阶段 RPE 房间的词法、分子的特征。而且,他们能在 Retinoic 酸(RA ) 和表明小径的声音的刺猬(嘘) 的激活之上获得色素沉着。我们的学习不仅建立了一个理想的平台调查调整 RPE 房间命运决心的 transcriptional 网络,而且提供了其他的策略产生为疾病建模,屏蔽的药,和网膜的退化的房间治疗补充 pluripotent 干细胞的使用的功能的 RPE 房间。 | Kejing Zhang Guang-Hui Liu Fei Yi Nuria Montserrat Tomoaki Hishida Concepcion Rodriguez Esteban Juan Carlos Izpisua Belmonte] | 2014 | Protein & Cell2014，5，1： | 6 |
| 4 | A widely adaptable approach to generate integration-free iPSCs from non-invasively acquired human somatic cells显示文摘 | Zhichao Ding Lina Sui Ruotong Ren Yanjun Liu Xiuling Xu Lina Fu Ruijun Bai Tingting Yuan Ying Hao Weiqi Zhang Huize Pan Wensu Liu Han Yu Concepcion Rodriguez Esteban Xiaobing Yu Ze Yang Jian Li Xiaomin Wang Juan Carlos Izpisua Belmonte Guang-Hui Liu Fei Yi Jing Qu | 2015 | Protein & Cell2015，6，5： | 5 |
| 5 | 菲律宾高等教育质量保障体系及实践显示文摘2008年11月6-7日,由上海市教育评估院主办、以'完善教育质量保障体系与运行机制'为主题的首届上海教育评估论坛在上海举办。来自亚太地区的130多位代表出席此次论坛。教育部原副部长吴启迪应邀作主旨报告,教育部高等教育教学评估中心主任季平、亚太地区多位知名教育质量保障专家及有关省市教育评估机构代表分别作专题报告。论论的成功举办,将对亚太地区各国教育质量保障领域的交流与合作、促进我国各级教育评估机构的能力建设、提升上海乃至全国教育质量质量起到积极推动作用。本期择要刊登部分专题报告的主要观点和内容,以飨读者。 | Concepcion V.Pijano | 2009 | 教育发展研究2009，29，3： | 3 |
| 6 | Bone Marrow Mesenchymal Stem Cells Stimulate Cardiac Stem Cell Proliferation and Differentiation显示文摘 | Konstantinos E. Hatzistergos Henry Quevedo Behzad N. Oskouei Qinghua Hu Gary S. Feigenbaum Irene S. Margitich Ramesh Mazhari Andrew J. Boyle Juan P. Zambrano Jose E. Rodriguez Raul Dulce Pradip M. Pattany David Valdes Concepcion Revilla Alan W. Heldman Ia | 2010 | Circulation Research2010，，7： | 2 |
| 7 | Precise in vivo genome editing via single homology arm donor mediated intron-targeting gene integration for genetic disease correction显示文摘In vivo genome editing represents a powerful strategy for both understanding basic biology and treating inherited diseases.However,it remains a challenge to develop universal and efficient in vivo genome-editing tools for tissues that comprise diverse cell types in either a dividing or non-dividing state.Here,we describe a versatile in vivo gene knock-in methodology that enables the targeting of a broad range of mutations and cell types through the insertion of a minigene at an intron of the target gene locus using an intracellularly linearized single homology arm donor.As a proof-of-concept,we focused on a mouse model of prematureaging caused by a dominant point mutation,which is difficult to repair using existing in vivo genome-editing tools.Systemic treatment using our new method ameliorated aging-associated phenotypes and extended animal lifespan,thus highlighting the potential of this methodology for a broad range of in vivo genome-editing applications. | Keiichiro Suzuki Mako Yamamoto Reyna Hernandez-Benitez Zhe Li Christopher Wei Rupa Devi Soligalla Emi Aizawa Fumiyuki Hatanaka Masakazu Kurita Pradeep Reddy Alejandro Ocampo Tomoaki Hishida Masahiro Sakurai Amy NNemeth Estrella Nunez Delicado Josep MCampistol Pierre Magistretti Pedro Guillen Concepcion Rodriguez Esteban Jianhui Gong Yilin Yuan Ying Gu Guang-Hui Liu Carlos Lopez-Otin Jun Wu Kun Zhang Juan Carlos Izpisua Belmonte | 2019 | Cell Research2019，29，10： | 2 |
| 8 | αKLOTHO and sTGFβR2 treatment counteract the osteoarthritic phenotype developed in a rat model显示文摘Dear Editor,Homeostasis and repair are critical biological processes that allow for tissue and organ preservation and function in multicellular organisms.Their regulation and extension vary drastically across the animal kingdom,and mammals show limited tissue-specific regenerative capacity that declines with age.During aging,articular cartilage is one of the tissues that undergo substantial changes in the matrix structure,molecular composition,metabolic activity,and mechanical properties(Loeser et al.2016). | Paloma Martinez-Redondo Isabel Guillen-Guillen Noah Davidsohn Chao Wang Javier Prieto Masakazu Kurita Fumiyuki Hatanaka Cuiqing Zhong Reyna Hernandez-Benitez Tomoaki Hishida Takashi Lezaki Akihisa Sakamoto Amy NNemeth Yuriko Hishida Concepcion Rodriguez Esteban Kensaku Shojima Ling Huang Maxim Shokhirev Estrella Nunez-Delicado Josep MCampistol Isabel Guillen-Vicente Elena Rodriguez-Inigo Juan Manuel Lopez-Alcorocho Marta Guillen-Vicente George Church Pradeep Reddy Pedro Guillen-Garcia Guang-Hui Liu Juan Carlos Izpisua Belmonte | 2020 | Protein & Cell2020，11，3： | 2 |
| 9 | Thoraco - scopic cervi- codorsal sympathectomy : preliminary re - suits 显示文摘 | Ahn SS Machleder HI Concepcion B | 1994 | J Vasc Surg1994，21，： | 1 |
| 10 | Quantification of lectin in freshwater prawn (Macrobrachium rosenbergii ) hemolymph by ELISA 显示文摘 | Concepcion Agundis Ali Pereyra Roberto Zenteno | 2000 | Compar Biochem Physiol2000，127，： | 1 |
| 11 | Autopsy Patterns of Disease Among Subgroups of an Inner-city Bronx AIDS Population显示文摘 | Markowitz G S Concepcion L Factor S M | 1996 | J Acquir Immune Defic Syndr Hum Retrovirol1996，13，1： | 1 |
| 12 | A C/T single-nucleotide polymorphism in the region of the CD40 gene is associated with Graves' disease 显示文摘 | Tomer Y Concepcion E Greenberg DA | 2002 | Thyroid2002，12，12： | 1 |
| 13 | Upper- airway obstruction and perioperative management of the airway in patients managed with posterior operations on the cervical spine for rheumatoid arthritis 显示文摘 | Wattenmaker I Concepcion M Hibberd P | 1994 | J Bone Joint Surg Am1994，76，36： | 1 |
| 14 | Obesity, body composition, and prostate cancer显示文摘 | Fowke JH Motley SS Concepcion RS | 2012 | BMC Cancer2012，12，： | 1 |
| 15 | Solventand thermal-induced crystallization ofpoly-L-lactic acid in supercritical CO2 medium显示文摘 | L P Ana A G G Carlos D Concepcion | 2009 | Applied Polymer Science2009，111，1： | 1 |
| 16 | Autoimmune thyroiditis and diabetes: dissecting the joint genetic susceptibility in a large cohort of multiplex families 显示文摘 | Villano MJ Huber AK Greenberg DA Golden BK Concepcion E Tomer Y | 2009 | J Clin Endocrinol Metab2009，94，4： | 1 |
| 17 | Polymorphisms for chemical metabolizing genes and risk for cervical neoplasia显示文摘 | Carlos H Sierra-Torres William W Au Concepcion D Arrastia | 2003 | Environmental and Molecular Mutagenesis2003，41，1： | 1 |
| 18 | Free radical scavenging capacity and inhibition of lipid oxidation of wines,grape juices and related polyphenolic constituents显示文摘 | SANCHEZ M CONCEPCION A LARRAURI | 1999 | Food Research International1999，32，： | 1 |
| 19 | Total abdominal evisceration: an en bloc technique for abdominal organ harvesting显示文摘 | Nakazato PZ Concepcion W Bry W | 1992 | Surgery1992，111，： | 1 |
| 20 | Raffinose family oligosaccharides and sucrose contents in 13 Spanish lupin cuhivars 显示文摘 | Cristina Martinez- Villaluenga Juana Frias Concepcion Vidal - Valverde | 2005 | Food Chemistry2005，91，4： | 1 |
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