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| 1 | IFC implementation in lifecycle costing显示文摘Life Cycle Costing (LCC) is always a major concern in the Architecture, Engineering and Construction (AEC) industry. This paper presents the implementation of Building Information Modeling (BIM) technology in the development of a lifecycle cost-estimating tool. The IFC (Industry Foundation Classes) model as an interoperable building information model has been adopted as the central data repository to deliver the integrated information of building designs from CAD design systems into the lifecycle-costing database. In this paper, the conceptions and relevant factors, which could affect the LCC estimation, have been introduced. The problems of current LCC applications have been identified as the lack of LCC data and the complexity of LCC exercises. The software application of IFC models and relevant auxiliary are depicted as a solution of the problem identified. The lifecycle costing tool is a part of the nD Modeling tool and as such is based on its integrated interface prototype toolkit and is able to holistically present an IFC model into a 3D virtual reality view, a tree-view and a list of element properties. The functions and some technical points are also detailed in the paper. Through the research, it demonstrates the potential and possibility of implementing BIM methods and techniques, particularly IFCs to enhance the computer applications in the processes of building construction and facility management. | Charlie Fu Ghassan Aouad Amanda Marshall Ponting Angela Lee Song Wu | 2004 | Journal of Harbin Institute of Technology(New Series)2004，11，4： | 7 |
| 2 | Review of small-bowel cleansing scales in capsule endoscopy: A panoply of choices显示文摘Evaluation of the quality of small-bowel cleansing is required to assess the reliability of findings in capsule endoscopy(CE). Moreover, consensus regarding the need of intestinal preparation for CE remains to be achieved. The presence of multiple grading scales for smallbowel preparation in CE, which are time-consuming and complicated, adds difficulty to the comparison of different small-bowel cleansing regimens and their application in clinical practice. Nowadays, a validated scale universally accepted for grading small-bowel cleansing is lacking. In fact, there are numerous grading systems with very different technical characteristics, namely, the parameters and the portion of the CE video that are analyzed, the objectivity of the analysis, the lesser or greater dependency on the operator, and the validation of the score. The authors performed a review which aims to systematize and summarize currently available smallbowel grading scales in CE. | Ana Ponte Rolando Pinho Adélia Rodrigues Joao Carvalho | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，17： | 6 |
| 3 | Novel functions of GABA signaling in adult neurogenesis显示文摘通过 ionotropic GABAA 和 metabotropic GABAB 受体的 Neurotransmitter gamma-aminobutiric 酸(伽马氨基丁酸) 在 neuronal 的开发,粘性和函数联网的 modulating 起关键作用。伽马氨基丁酸在成熟神经原是禁止的但是在不成熟的神经原,神经母细胞和神经干细胞(NSCs/NPCs ) 有刺激性。开关从对有刺激性禁止发生在驾驶 Cl 流入和驾驶 Cl 的神经原特定的 K+/Cl co 搬运 KCC2 的 Na+/K+/2Cl co 搬运 NKCC1 的表示从动态变化跟随 glutamatergic synaptic 输入和结果的发展流出。KCC2 表示的发展转变被 Disrupted-in-Schizophrenia 1 (DISC1 ) 和发信号的导出大脑的神经营养的因素(BDNF ) 调整。在早神经发生期间发信号的有刺激性的伽马氨基丁酸对 NSC 静止, NPC 增长,神经母细胞迁居和新生的 neuronal maturation/functional 集成的 activity/experience-induced 规定重要。发信号的禁止的伽马氨基丁酸允许为 learning/memory 开发和维护的稀少、静态的功能的联网必需品。 | Adalto PONTES Yonggang ZHANG Wenhui HU | 2013 | Frontiers in Biology2013，8，5： | 5 |
| 4 | Evolution and Functions of Long Noncoding RNAs显示文摘 | Chris P. Ponting Peter L. Oliver Wolf Reik | 2009 | Cell2009，，4： | 5 |
| 5 | Maxillofacial and concomitant serious injuries: An eight-year single center experience显示文摘 | Fausto Fama Marco Cicciu Alessandro Sindoni Enrico Nastro-Siniscalchi Roberto Falzea Gabriele Cervino Francesca Polito Francesco De Ponte Maria Gioffre-Florio | 2017 | Chinese Journal of Traumatology2017，20，1： | 4 |
| 6 | Propofol vs midazolam sedation for elective endoscopy in patients with cirrhosis:A systematic review and meta-analysis of randomized controlled trials显示文摘BACKGROUND Patients with cirrhosis frequently require sedation for elective endoscopic procedures.Several sedation protocols are available,but choosing an appropriate sedative in patients with cirrhosis is challenging.AIM To conduct a systematic review and meta-analysis to compare propofol and midazolam for sedation in patients with cirrhosis during elective endoscopic procedures in an attempt to understand the best approach.METHODS This systematic review and meta-analysis was conducted using the PRISMA guidelines.Electronic searches were performed using MEDLINE,EMBASE,Central Cochrane,LILACS databases.Only randomized control trials(RCTs)were included.The outcomes studied were procedure time,recovery time,discharge time,and adverse events(bradycardia,hypotension,and hypoxemia).The risk of bias assessment was performed using the Revised Cochrane Risk-of-Bias tool for randomized trials(RoB-2).Quality of evidence was evaluated by GRADEpro.The meta-analysis was performed using Review Manager.RESULTS The search yielded 3,576 records.Out of these,8 RCTs with a total of 596 patients(302 in the propofol group and 294 in the midazolam group)were included for the final analysis.Procedure time was similar between midazolam and propofol groups(MD:0.25,95%CI:-0.64 to 1.13,P=0.59).Recovery time(MD:-8.19,95%CI:-10.59 to-5.79,P<0.00001).and discharge time were significantly less in the propofol group(MD:-12.98,95%CI:-18.46 to-7.50,P<0.00001).Adverse events were similar in both groups(RD:0.02,95%CI:0-0.04,P=0.58).Moreover,no significant difference was found for bradycardia(RD:0.03,95%CI:-0.01 to 0.07,P=0.16),hypotension(RD:0.03,95%CI:-0.01 to 0.07,P=0.17),and hypoxemia(RD:0.00,95%CI:-0.04 to 0.04,P=0.93).Five studies had low risk of bias,two demonstrated some concerns,and one presented high risk.The quality of the evidence was very low for procedure time,recovery time,and adverse events;while low for discharge time.CONCLUSION This systematic review and meta-analysis based on RCTs show that propofol has shorter recovery and patient discharge time as compared to midazolam with a similar rate of adverse events.These results suggest that propofol should be the preferred agent for sedation in patients with cirrhosis. | John Alexander Lata Guacho Diogo Turiani Hourneaux de Moura Igor Braga Ribeiro Alberto Machado da Ponte Neto Shailendra Singh Marina Gammaro Baldavira Tucci Wanderley Marques Bernardo Eduardo Guimarães Hourneaux de Moura | 2020 | World Journal of Gastrointestinal Endoscopy2020，12，8： | 4 |
| 7 | Application of Bioinspired Superhydrophobic Surfaces in Two-phase Heat Transfer Experiments显示文摘 | Emanuele Teodori Ana Sofia Moita Miguel Moura Pedro Pontes Antonio Moreira Yuan Bai Xinlin Li Yan Liu | 2017 | Journal of Bionic Engineering2017，14，3： | 3 |
| 8 | Solitary and Multiple Isolated Metastases of Clear Cell Renal Carcinoma to the Pancreas: An Indication for Pancreatic Surgery显示文摘 | Franz Sellner MD Natascha Tykalsky MD Maria Santis MD J?rg Pont MD M. Klimpfinger MD | 2006 | Annals of Surgical Oncology2006，，1： | 3 |
| 9 | Potential role of Limosilactobacillus fermentum as a probiotic with anti-diabetic properties: A review显示文摘Oxidative stress,inflammation,and gut microbiota impairments have been implicated in the development and maintenance of diabetes mellitus.Strategies capable of recovering the community of commensal gut microbiota and controlling diabetes mellitus have increased in recent years.Some lactobacilli strains have an antioxidant and anti-inflammatory system capable of protecting against oxidative stress,inflammation,and diabetes mellitus.Experimental studies and some clinical trials have demonstrated that Limosilactobacillus fermentum strains can beneficially modulate the host antioxidant and anti-inflammatory system,resulting in the amelioration of glucose homeostasis in diabetic conditions.This review presents and discusses the currently available studies on the identification of Limosilactobacillus fermentum strains with anti-diabetic properties,their sources,range of dosage,and the intervention time in experiments with animals and clinical trials.This review strives to serve as a relevant and well-cataloged reference of Limosilactobacillus fermentum strains capable of inducing anti-diabetic effects and promoting health benefits. | Diego Cabral Lacerda Paulo César Trindade da Costa Paula Brielle Pontes Lucas Alves Carneiro dos Santos JoséPatrocínio Ribeiro Cruz Neto Cristiane Cosmo Silva Luis Vanessa Polyana de Sousa Brito JoséLuiz de Brito Alves | 2022 | World Journal of Diabetes2022，13，9： | 3 |
| 10 | Molecular mechanisms of liver preconditioning显示文摘Ischemia/reperfusion (I/R) injury still represents an important cause of morbidity following hepatic surgery and limits the use of marginal livers in hepatic transplantation. Transient blood flow interruption followed by reperfusion protects tissues against damage induced by subsequent I/R. This process known as ischemic pre-conditioning (IP) depends upon intrinsic cytoprotective systems whose activation can inhibit the progression of irreversible tissue damage. Compared to other organs,liver IP has additional features as it reduces inflammation and promotes hepatic regeneration. Our present understanding of the molecular mechanisms involved in liver IP is still largely incomplete. Experimental studies have shown that the protective effects of liver IP are triggered by the release of adenosine and nitric oxide and the subsequent activation of signal networks involving protein kinases such as phosphatidylinositol 3-kinase,protein kinase C δ/ε and p38 MAP kinase,and transcription factors such as signal transducer and activator of transcription 3,nuclear factor-κB and hypoxia-inducible factor 1. This article offers an overview of the molecular events underlying the preconditioning effects in the liver and points to the possibility of developing pharmacological approaches aimed at activating the intrinsic protective systems in patients undergoing liver surgery. | Elisa Alchera Caterina Dal Ponte Chiara Imarisio Emanuele Albano Rita Carini | 2010 | World Journal of Gastroenterology2010，16，48： | 3 |
| 11 | SSJD14080400004873显示文摘 | Roberto Galuppo Dinesh Ramaiah Oscar Moreno Ponte Roberto Gedaly | 2014 | Digestive Diseases and Sciences2014，，8： | 2 |
| 12 | Histomorhological and clinical evaluation of maxillary alveolar ridge reconstruction after craniofacial trauma by applying combination of allogeneic and autogenous bone graft显示文摘 | Francesco Saverio De Ponte Roberto Falzea Michele Runci Enrico Nastro Siniscalchi Floriana Lauritano Ennio Bramanti Gabriele Cervino Marco Cicciu | 2017 | Chinese Journal of Traumatology2017，20，1： | 2 |
| 13 | Research on aerosol sources and chemical composition: Past, current and emerging issues显示文摘 | A.I. Calvo C. Alves A. Castro V. Pont A.M. Vicente R. Fraile | 2013 | Atmospheric Research2013，，： | 2 |
| 14 | Susceptibility Genetic Variants Associated With Colorectal Cancer Risk Correlate With Cancer Phenotype显示文摘 | Anna Abulí Xavier Bessa Juan Ramón González Clara Ruiz–Ponte Alejandro Cáceres Jenifer Mu?oz Victoria Gonzalo Francesc Balaguer Ceres Fernández–Rozadilla Dolors González Luisa de Castro Juan Clofent Luís Bujanda Joaquín Cubiella Josep M a Re?é Juan Diego | 2010 | Gastroenterology2010，，3： | 2 |
| 15 | Can baseline ML Flow test results predict leprosy reactions? An investigation in a cohort of patients enrolled in the uniform multidrug therapy clinical trial for leprosy patients in Brazil显示文摘Background:The predictive value of the serology to detection of IgM against the Mycobacterium leprae-derived phenolic glycolipid-I/PGL-I to identify leprosy patients who are at higher risk of developing reactions remains controversial.Whether baseline results of the ML Flow test can predict leprosy reactions was investigated among a cohort of patients enrolled in The Clinical Trial for Uniform Multidrug Therapy for Leprosy Patients in Brazil(U-MDT/CT-BR).Methods:This was a descriptive study focusing on the main clinical manifestations of leprosy patients enrolled in the U-MDT/CT-BR from March 2007 to February 2012 at two Brazilian leprosy reference centers.For research purposes,753 leprosy patients were categorized according to a modified Ridley-Jopling(R&J)classification and according to the development of leprosy reactions(reversal reaction/RR and erythema nodosum leprosum/ENL),and whether they had a positive or negative bacillary index/BI.Results:More than half of the patients(55.5%)reported leprosy reaction:18.3%(138/753)had a RR and 5.4%(41/753)had ENL.Leprosy reactions were more frequent in the first year following diagnosis,as seen in 27%(205/753)of patients,while 19%(142/753)developed reactions during subsequent follow-up.Similar frequencies of leprosy reactions and other clinical manifestations were observed in paucibacillary(PB)and multibacillary(MB)leprosy patients treated with U-MDT and regular MDT(R-MDT)(P=0.43 and P=0.61,respectively).Compared with PB patients,leprosy reactions were significantly more frequent in MB patients with a high BI,and more patients developed RR than ENL.However,RR and neuritis were also reported in patients with a negative BI.At baseline,the highest rate of ML Flow positivity was observed in patients with a positive BI,especially those who developed ENL,followed by patients who had neuritis and RR.Among reaction-free patients,81.9%were ML Flow positive,however,the differences were not statistically significant compared to reactional patients(P=0.45).Conclusions:MB and PB patients treated with R-MDT and U-MDT showed similar frequencies of RR and other clinical manifestations.Positive ML Flow tests were associated with MB leprosy and BI positivity.However,ML Flow test results at baseline showed limited sensitivity and specificity for predicting the development of leprosy reactions. | Emerith Mayra Hungria Regiane Morillas Oliveira Gerson Oliveira Penna Lúcio Cartaxo Aderaldo Maria Araci de Andrade Pontes Rossilene Cruz Heitor de SáGonçalves Maria Lúcia Fernandes Penna Ligia Regina Franco Sansigolo Kerr Mariane Martins de Araújo Stefani Samira Bührer-Sékula | 2016 | Infectious Diseases of Poverty2016，5，1： | 2 |
| 16 | The course of inflammatory bowel disease during pregnancy and postpartum: a prospective European ECCO‐EpiCom Study of 209 pregnant women显示文摘 | N. Pedersen A. Bortoli D. Duricova R. D′Inca M. R. Panelli J. P. Gisbert G. Zoli A. López‐Sanromán F. Castiglione G. Riegler V. Annese P. Gionchetti A. Prada E. D. Pont A. Timmer C. Felley M. Shuhaibar E. V. Tsianos C. Dejaco F. J. Baert T. Jess M. Lebech | 2013 | Aliment Pharmacol Ther2013，，5： | 2 |
| 17 | Calprotectin and lactoferrin in the assessment of intestinal inflammation and organic disease显示文摘 | Renata D’Incà Elisabetta Pont Vincenza Leo Antonio Ferronato Walter Fries Maria Grazia Vettorato Diego Martines Giacomo Carlo Sturniolo | 2007 | International Journal of Colorectal Disease2007，，4： | 2 |
| 18 | 中国能源系统脱碳以支撑巴黎气候目标显示文摘As the largest emitter of greenhouse gas(GHG)now,China’s“long-term low greenhouse gas emission development strategies”(LTS)will be important to the success of the Paris climate goals to limit global warming to well below 2 or 1.5℃by the end of this century.In September 2020,China surprised the international community by announcing carbon neutrality before 2060. | 潘勋章 王利宁 陈文颖 Yann Robiou du Pont Leon Clarke 杨雷 王海林 鲁玺 何建坤 | 2022 | Science Bulletin2022，67，14： | 2 |
| 19 | RNA Polymerase V Functions in Arabidopsis Interphase Heterochromatin Organization Independently of the 24-nt siRNA-Directed DNA Methylation Pathway显示文摘在 Arabidopsis, pericentromeric 重复, retroelements,和 silenced rRNA,基因在作为 chromocenters 知道的原子结构以内被装配进 heterochromatin。管理高顺序的 heterochromatin 组织的机制糟糕被理解但是 24-nt 小介入 RNA (siRNAs ) 被知道在 heterochromatin 起关键作用形成。原子 RNA 聚合酶 IV (Pol IV ) , RNA 依赖的 RNA 聚合酶 2 (RDR2 ) ,并且像骰子(DCL3 ) 3 为 24-nt siRNAs 的生物的续生说被要求有 ARGONAUTE 4 (AGO4 ) 的那个伙伴。原子 RNA 聚合酶 V (Pol V ) 与 DRD1 协作(在 RNA 依赖的 DNA METHYLATION 1 缺乏) 招募在被假设绑在 siRNA-AGO4 建筑群并且随后的包含不同颜色的 loci 产生抄本 de-novo DNA methylation 或 histone 修改机械。这里,我们报导主要 pericentromeric 重复和包含不同颜色的标记 histone H3 离氨酸的弄空的那 decondensation 在 chromocenters 的 9 dimethylation 在 pol V 和 drd1 异种明确地发生。pericentromeric 重复冷凝作用的混乱与 pericentromeric 180-bp 重复的特定的班的 transcriptional 复活是重合的。我们进一步证明 Pol V 独立于 Pol IV, RDR2,和影响分裂期间 heterochromatin 组织的调停 DCL3 的 siRNA 生产工作,可能由包含招募的 RNA 结构或修改染色质的蛋白质。 | Olga Pontes Pedro Costa-Nunes Paul Vithayathil Craig S. Pikaard | 2009 | Molecular Plant2009，2，4： | 2 |
| 20 | Inhibitory receptors sensing HLA-G1 molecules in pregnancy: deciduaassociated natural killer cells express LIR-1 and CD94/ NKG2A and acquire p49, an HLA-Gl-specific receptor 显示文摘 | Ponte M Cantoni C Biassoni R | 1999 | Proc Natl Acad Sci U S A1999，96，： | 1 |
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