|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Effect of multiple-phase regional intra-arterial infusion chemotherapy on patients with resectable pancreatic head adenocarcinoma显示文摘背景地区性的intra动脉的注入化疗( RIAC )是更珍贵的与不能实行的胰腺的腺癌改进病人的生活的预后和质量,并且辅助 RIAC 在延长幸存并且在胰腺的癌症的激进的切除术以后减少肝转移的风险起一个重要作用,但是外科手术前或多重阶段的 RIAC 的效果(外科手术前与手术后的 RIAC 结合了)为 resectable ,胰腺的癌症没被调查。在这未来的研究,为有 resectable 的病人的多重阶段的 RIAC 的效果胰腺的头腺癌被评估,并且它与手术后的 RIAC 作比较的安全和有效性也是有胰腺的头癌症随机被分到二个组的 resectable 的 assessed.Methods 病人。在组 A (n=50 ) 的病人与与多重阶段的 RIAC 相结合的扩大 pancreaticoduodenectomy 的新治疗学的模式被对待,并且那些在组 B (n=50 ) 被对待,扩大 pancreaticoduodenectomy 在一样的时期与手术后的 RIAC 结合了。新治疗学的模式的可行性,依从和效率被 RIAC 的肿瘤尺寸,浆液肿瘤标记,临床的利益反应(CBR ) ,外科的复杂并发症,死亡和毒性评估。没有疾病的幸存时间,中部的幸存时间,肝转移的发生,在 1, 2, 3 和 5 年的幸存率也被观察。生活曲线被在组 A 的疼痛消除率和 CBR 是的 Kaplan-Meier method.Results 产生 80% 和 84% 分别地。浆液肿瘤标记显然减少了,肿瘤尺寸在组 A 在外科手术前的 RIAC 以后在 26% 病人减少了。不再外科的复杂并发症,死亡或严重全身的副作用与组 B 相比在组 A 被观察。在组 A 的肝转移的发生是 34% 它在组 B 是比 50% 低的。在组 A 的没有疾病的幸存时间和中部的幸存时间分别地是 15.5 个月和 18 个月。1- , 2- , 3 年、 5 年的幸存率分别地是 54.87% , 34.94% , 24.51% 和 12.25% 。没有在多重阶段的 RIAC 是的二 groups.Conclusions 之间的幸存时间或幸存率的重要差别在 resectable 的联合治疗有效由提高肿瘤生长和肝转移的减小的抑制的胰腺的头癌,没有病人的安全或外科的过程上的否定效果。 | JIN Chen YAO Lie LONG Jiang FU De-liang YU Xian-jun XU Jin YANG Feng NI Quan-xing | 2009 | Chinese Medical Journal2009，，3： | 17 |
| 2 | Is routine drainage necessary after pancreaticoduodenectomy?显示文摘With the development of imaging technology and surgical techniques, pancreatic resections to treat pancreatic tumors, ampulla tumors, and other pancreatic diseases have increased. Pancreaticoduodenectomy, one type of pancreatic resection, is a complex surgery with the loss of pancreatic integrity and various anastomoses. Complications after pancreaticoduodenectomy such as pancreatic fistulas and anastomosis leakage are common and significantly associated with patient outcomes. Pancreatic fistula is one of the most important postoperative complications; this condition can cause intraperitoneal hemorrhage, septic shock, or even death. An effective way has not yet been found to avoid the occurrence of pancreatic fistula. In most medical centers, the frequency of pancreatic fistula has remained between 9% and 13%. The early detection and routine drainage of anastomotic fistulas, pancreatic fistulas, bleeding, or other intra-abdominal fluid collections after pancreatic resections are considered as important and effective ways to reduce postoperative complications and the mortality rate. However, many recent studies have argued that routine drainage after abdominal operations, including pancreaticoduodenectomies, does not affect the incidence of postoperative complications. Although inserting drains after pancreatic resectionscontinues to be a routine procedure, its necessity remains controversial. This article reviews studies of the advantages and disadvantages of routine drainage after pancreaticoduodenectomy and discusses the necessity of this procedure. | Qiang Wang Yong-Jian Jiang Ji Li Feng Yang Yang Di Lie Yao Chen Jin De-Liang Fu | 2014 | World Journal of Gastroenterology2014，20，25： | 7 |
| 3 | Accuracy of routine multidetector computed tomography to identify arterial variants in patients scheduled for pancreaticoduodenectomy显示文摘AIM:To assess the efficacy of cross-sectional multidetector computed tomography(MDCT) imaging without arterialreconstruction to identify aberrant right hepatic artery(RHA) and celiac artery stenosis(CAS) in patients scheduled for pancreaticoduodenectomy.METHODS:Patients with peri-ampullary and pancreatic head tumors who underwent routine preoperative MDCT and subsequent computed tomography(CT) angiography(CTA),conventional angiography or pancreaticoduodenectomy between September 2007 and August 2013 were identified.Retrospective analysis of imaging data was undertaken using CTA,conventional angiographic and surgical findings as the reference standards.The accuracy,sensitivity,specificity,positive predictive value(PPV) and negative predictive value(NPV) of MDCT in evaluation of aberrant RHA and CAS were calculated.RESULTS:A group of 458 patients met the inclusion criteria of this study to detect aberrant RHA,and 181 cases were included to identify CAS.Fifty-four(11.8%) patients were confirmed to have aberrant RHA,while 12(6.6%) patients with CAS were demonstrated.MDCT yielded an accuracy of 98.5%,sensitivity of 96.3% and specificity of 98.8% in the detection of aberrant RHA.The sensitivity,specificity,PPV and NPV of MDCT for detecting CAS were 58.3%,98.2%,70% and 97.1%,respectively.CONCLUSION:Routine MDCT is recommended such that surgeons and radiologists be alerted to the importance of arterial variants on preoperative CT scans in patients scheduled for pancreaticoduodenectomy. | Feng Yang Yang Di Ji Li Xiao-Yi Wang Lie Yao Si-Jie Hao Yong-Jian Jiang Chen Jin De-Liang Fu | 2015 | World Journal of Gastroenterology2015，21，3： | 6 |
| 4 | Bone marrow mononuclear cell transplantation promotes therapeutic angiogenesis via upregulation of the VEGF–VEGFR2 signaling pathway in a rat model of vascular dementia显示文摘 | Jianping Wang Xiaojie Fu Chao Jiang Lie Yu Menghan Wang Wei Han Liu Liu Jian Wang | 2014 | Behavioural Brain Research2014，，： | 2 |
| 5 | Partial pancreatic tail preserving subtotal pancreatectomy forpancreatic cancer: Improving glycemic control and quality of lifewithout compromising oncological outcomes显示文摘BACKGROUND Total pancreatectomy (TP) is usually considered a therapeutic option forpancreatic cancer in which Whipple surgery and distal pancreatectomy areundesirable, but brittle diabetes and poor quality of life (QoL) remain majorconcerns. A subset of patients who underwent TP even died due to severehypoglycemia. For pancreatic cancer involving the pancreatic head and proximalbody but without invasion to the pancreatic tail, we performed partial pancreatictail preserving subtotal pancreatectomy (PPTP-SP) in selected patients, in order toimprove postoperative glycemic control and QoL without compromisingoncological outcomes.AIM To evaluate the efficacy of PPTP-SP for patients with pancreatic cancer.METHODS We retrospectively reviewed 56 patients with pancreatic ductal adenocarcinomawho underwent PPTP-SP (n = 18) or TP (n = 38) at our institution from May 2014to January 2019. Clinical outcomes were compared between the two groups, withan emphasis on oncological outcomes, postoperative glycemic control, and QoL.QoL was evaluated using the European Organization for Research and Treatmentof Cancer Quality of Life Questionnaire (EORTC QLQ-C30 and EORTC PAN26).All patients were followed until May 2019 or until death.RESULTS A total of 56 consecutive patients were enrolled in this study. Perioperativeoutcomes, recurrence-free survival, and overall survival were comparablebetween the two groups. No patients in the PPTP-SP group developed cancerrecurrence in the pancreatic tail stump or splenic hilum, or a clinical pancreaticfistula. Patients who underwent PPTP-SP had significantly better glycemiccontrol, based on their higher rate of insulin-independence (P = 0.014), lowerhemoglobin A1c (HbA1c) level (P = 0.046), lower daily insulin dosage (P < 0.001),and less frequent hypoglycemic episodes (P < 0.001). Global health was similar inthe two groups, but patients who underwent PPTP-SP had better functional status(P = 0.036), milder symptoms (P = 0.013), less severe diet restriction (P = 0.011),and higher confidence regarding future life (P = 0.035).CONCLUSION For pancreatic cancer involving the pancreatic head and proximal body, PPTP-SPachieves perioperative and oncological outcomes comparable to TP in selectedpatients while significantly improving long-term glycemic control and QoL. | Li You Lie Yao Yi-Shen Mao Cai-Feng Zou Chen Jin De-Liang Fu | 2020 | World Journal of Gastrointestinal Surgery2020，12，12： | 1 |
| 6 | 显示文摘 | Yin Cheng Lie | 1997 | Chin Chem Let1997，8，12： | 1 |
| 7 | The microRNA-218 and ROBO-1 signaling axis correlates with the lymphaticmetastasis of pancreatic cancer显示文摘 | Hang He Yang Di Minrui Liang Feng Yang Lie Yao Sijie Hao Ji Li Yongjian Jiang Chen Jin Deliang Fu | 2013 | Oncology Reports2013，，2： | 1 |
| 8 | Phylogenetic relationships and possible hybrid origin of Lycoris species (Amaryllidaceae)revealed by ITS sequences显示文摘 | SHI S D QIU Y X LIE X WU L FU C X | 2006 | Biochemical Genetics2006，44，5： | 1 |
| 9 | How to Improve the Efficacy of Endoscopic Ultrasound-guided Celiac Plexus Neurolysis in Pain Management in Patients With Pancreatic Cancer: Analysis in a Single Center显示文摘 | Hao Si-Jie Xu Wei-Jia Di Yang Yao Lie Yang Feng Jiang Yong-Jian Li Ji Jin Chen Zhong Liang Fu De-Liang | 2014 | Surgical Laparoscopy, Endoscopy & Percutaneous Techniques2014，，： | 1 |
| 10 | Effects of Region and Elevation on Adaptation of Leaf Functional Traits of an Invasive Plant Erigeron annuus in China显示文摘A key scientific challenge relating to the threat of invasive plants on agriculture at the region level is to understand their adaptation and evolution in functional traits.Leaf functional traits,related to growth and resource utilization,might lead to adaptation of invasive plants to the geographical barriers(region or elevation).In the field experiment,we discussed the effects of region and elevation on leaf functional traits on invasive plant Erigeron annuus in farmland habitats in China.We compared leaf size,coefficient of variation(CV)of leaf traits,and fluctuating asymmetry(FA)of E.annuus from three regions(east vs.center vs.west)and two leaf types(vegetative vs.reproductive leaf),and from nine elevations(980-2100 m)in the west region of China.Our results indicated region and leaf type influenced leaf functional traits,and leaf size was significantly higher and CV of leaf traits and FA in reproductive leaves were significantly lower in the east region than in the west and center regions.Elevation and leaf type affected leaf functional traits,and leaf size was significantly higher and CV of leaf traits in reproductive leaves were significantly lower in moderate elevation.E.annuus has higher leaf size and developmental stability(lower CV and FA)in the eastern region due to the longer adaptation period.Therefore,leaf functional traits play an important role in the adaptation of different longitudes and elevations.It can also facilitate the understanding of the invasiveness and adaptation of leaf traits of invasive plants in the agricultural ecosystem during their spread process in China. | Yuanyuan Liu Zhen Li Lie Xu Qiang Fu Yongjian Wang | 2022 | Phyton-International Journal of Experimental Botany2022，91，1： | 0 |
| 11 | Perovskite photodetector-based single pixel color camera for artificial vision显示文摘Narrowband red,green,blue self-filtering perovskite photodetectors and a broadband white photodetector are incorporated into a single pixel imaging camera to mimic the long-,medium-,and short-wavelength cone cells and rod cells in human visual system,leading to the demonstration of high-resolution color images in diffuse mode. | Chaohao Chen Ziyuan Lie Lan Fu | 2023 | Light(Science & Applications)2023，12，4： | 0 |
| 12 | Conformational Analysis of γ-Butyrolactones by Nuclear Magnetic Resonance Spectroscopy显示文摘A series of trans-4, 5-disubstituted -γ-butyrolactones are found to assume two different envelope conformations by means of nuclear magnetic resonance spectroscopy. | Fu An KANG and Cheng Lie YIN (Department of Chemistry Beijing Normal University , Beijing 100875) | 1997 | Chinese Chemical Letters1997，8，10： | 0 |
| 13 | Asymmetric Trimethylsilylcyanation of Benzaldebyde Catalyzed by Novel Ti(Ⅳ)-Chiral Schiff Base Complexes显示文摘Benzaldehyde has been trimethylsilylcyanated with a catalyst prepared in situ from titanium tetraisopropoxide and chiral Schiff bases. Cyanohydrin is obtalned in moderate e.e. | Guo Fu ZI Cheng Lie YIN(Department of Chemistry, Beijing Normal University, Beijing, 100875) | 1997 | Chinese Chemical Letters1997，8，12： | 0 |
| 14 | Asymmetric 1,3-Dipolar Cycloaddition of the Chiral Nitronic Esters with Acrylate显示文摘Asymmetric 1,3-dipolar cycloaddihon of the chiral nitronic esters with acrylate giving the enantiomerically pure novel chiral bisheterocyclic compounds is | Fu An KANG and Cheng Lie Ym(Department of Chemiscy Beijtw Normal Unthersho Beijing 100875) | 1997 | Chinese Chemical Letters1997，8，12： | 0 |
| 15 | Winter Hardiness Physiological Response with Dehydration in Winter Wheat显示文摘Freezing stress presents a severe threat for winter wheat(Triticum aestivum L.)during overwintering.Dehydration plays a significant role in plant cold-hardiness.In this study,dehydration-related traits were investigated between highly and tender freezing-tolerant winter wheat cultivars during the overwintering period.Accompanied by a decrease in temperature,the water content in crowns of highly freezing-tolerant winter wheat was significantly lower compared to that of tender freezing-tolerant winter wheat(control).The ratio of free and bound water content had slight changes in highly freezing-tolerant winter wheat,though there were wide fluctuations in the control.The transcript levels of dehydration-related genes were more expressed in the highly freezing-tolerant winter wheat than those in the control under freezing stress.The plant growth also showed significant differences between the two winter wheat cultivars.Based on these results,the study proposed that the highly freezing-tolerant winter wheat produces higher expression of dehydrins under freezing stress,causing additional dehydration in the tissue to avoid cell death caused by the formation of ice crystals.Furthermore,winter hardy cultivar also reduced the percentage of free water content that inhibited plant growth,and regulated the water composition for plant survival under freezing stress. | Qin Peng Zhao Lie Wang Xiao-nan Li Tong Fu Lian-shuang Wang Tao Li Zhuo-fu Liu Xin | 2020 | Journal of Northeast Agricultural University(English Edition)2020，27，3： | 0 |
| 16 | Novel and supplementary management of pancreatic fluid collections:Endoscopic ultrasound-guided drainage显示文摘AIM To compare efficacy and safety of endoscopic ultrasound (EUS)-guided and surgical drainage in pancreatic fluid collection management.METHODS Data were obtained retrospectively from January 2012 to December 2016.Patients with pancreatic fluid collection were performed EUS-guided or surgical procedure.Main outcome measures including clinical efficiency,complication,duration of procedures,hospital stay and cost were analyzed.RESULTS Thirty-six patients were enrolled into the study,including 14 in endoscopic group while 22 in the surgical group.Twelve (86%) patients were treated successfully by endoscopic approach while 21 (95%) patients benefited through surgical procedure.Endoscopic treatment had higher recurrence and complication rates than surgery,resulting in more re-interventions.Meanwhile,duration of procedure,hospital stay and cost were significantly lower in endoscopic group.CONCLUSION Both approaches were effective and safe.EUS-guided approach should be the first-line treatment in mild and simple cases,while surgical approach should be considered as priority in severe and complex cases. | Si-Jie Hao Wei-Jia Xu Yang Di Lie Yao Hang He Feng Yang Chen Jin Liang Zhong De-Liang Fu | 2017 | World Journal of Gastrointestinal Endoscopy2017，9，9： | 0 |
| 17 | Synthesis of a Fully Biobased Polyfunctional Vinyl Oligomer and Their UV Cured Films Prepared via Thiol-ene Coupling显示文摘In this paper,a fully bio-based vinyl oligomer with high functionalities was successfully prepared from rapeseed oil by three modification steps:epoxidation of rapeseed oil,solvent-free and catalyst-free ring opening by 10-undecylenic acid followed by esterification with 10-undecenoyl chloride.Then,the renewable polymers were prepared by photo-polymerization of these modified vegetable oils with typical thiol monomers:pentaerythritol tetrakis(3-mercaptopropionate),pentaerythritol tris(3-mercaptopropionate)and 1,2-ethanedithiol.The synthesis of the vinyl oligomer was monitored by nuclear magnetic resonance and Fourier-transform infrared spectroscopy.The average number of the carbon-carbon double bonds of the resulting vinyl oligomer is high to be 7.2.The kinetic of thiol-ene photo-polymerization of vegetable oil-based vinyl oligomer was studied by FTIR-ATR analyses.In addition,the thermo-physical properties,thermal stability and solvent resistance of these UV cured films were characterized.The polymers from 1,2-ethanedithiol exhibit higher gel content,storage modulus and glass transition temperature than those from other thiol monomers due to the high crosslinking densities of the resulting polymers.All polymers show excellent thermal stability up to 290oC.The resulting polymers exhibit thermo-physical properties,excellent water resistance and thermals stability,which is promising to find application in coatings and adhesives. | Changqing Fu Jiahui Wang Lie Chen Liang Shen | 2019 | Journal of Renewable Materials2019，7，8： | 0 |
| 18 | Asymmetric Conjugate Addition of Alcohols to (R)-(-)-5-[(1R,2S,5R)-Menthyloxy]-2-(5H)-Furanone显示文摘A series of enantiomencally pure (4R,5R)-(-)-4-alkryloxy-5-[(1R,2dihydro-2(5H)-furanones (2) have been synthesized in excellent yields via asymmetric conjugateadditions of primary alcohols to (R)-(-)-5-[(1R,2S,5R)-menthyloxy]-2(5H)-furanone (1) in the presenceof a catalytic amount of sodium in DMF, which provides access to new multifunctional homochiralbuilding blocks, optically. pure (R) or (S)-2-alkyloxy- 1,4-butanediols (3). | Fu An KANG Hong Yi YIN and Cheng Lie YIN(Departmenl of Chemistry, Beijing Normal Uviiversity, Beijing 100875) | 1997 | Chinese Chemical Letters1997，8，5： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员