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| 1 | Map and analysis of microsatellites in the genome of Populus: The first sequenced perennial plant显示文摘Environmental Sciences Division, Oak Ridge National Laboratory, TN, USA We mapped and analyzed the microsatellites throughout 284295605 base pairs of the unambiguously assembled sequence scaffolds along 19 chromosomes of the haploid poplar genome. Totally, we found 150985 SSRs with repeat unit lengths between 2 and 5 bp. The established microsatellite physical map demonstrated tr at SSRs were distributed relatively evenly across the genome of Populus. On average, These SSRs occurred every 1883 bp within the poplar genome and the SSR densities in intergenic regions, introns, exons and UTRs were 85.4%, 10.7%, 2.7% and 1.2%, respectively. We took di-, tri-, tetra-and pentamers as the four classes of repeat units and found that the density of each class of SSRs decreased with the repeat unit lengths except for the tetranucleotide repeats. It was noteworthy that the length diversification of microsatellite sequences was negatively correlated with their repeat unit length and the SSRs with shorter repeat units gained repeats faster than the SSRs with longer repeat units. We also found that the GC content of poplar sequence significantly correlated with densities of SSRs with uneven repeat unit lengths (tri-and penta-), but had no significant correlation with densities of SSRs with even repeat unit lengths (di-and tetra-). In poplar genome, there were evidences that the occurrence of different microsatellites was under selection and the GC content in SSR sequences was found to significantly relate to the functional importance of microsatellites. | LI ShuXian & YIN TongMing College of Environment and Forest Resources, Nanjing Forestry University, Nanjing 210037, China Environmental Sciences Division, Oak Ridge National Laboratory, TN, USA | 2007 | Science China(Life Sciences)2007，50，5： | 25 |
| 2 | Use of a clinical pathway in laparoscopic gastrectomy for gastric cancer显示文摘AIM: To evaluate the implementation of a clinical pathway and identify clinical factors affecting the clinical pathway for laparoscopic gastrectomy.METHODS: A standardized clinical pathway for gastric cancer(GC) patients was developed in 2001 by the GC surgery team at the Asan Medical Center. We reviewed the collected data of 4800 consecutive patients treated using the clinical pathway following laparoscopic gastrectomy with lymph node dissection for GC involving intracorporeal and extracorporeal anastomosis. The patients were treated between August 2004 and October 2013 in a single institution. To evaluate the rate of completion and risk factors affecting dropout from the clinical pathway, we used a multivariate logistic regression analysis.RESULTS: The overall completion rate of the clinical pathway for laparoscopic gastrectomy was 84.1%(n = 4038). In the comparison between groups of intracorporeal anastomosis and extracorporeal anastomosis patients, the completion rates were 8 3. 8 8 %(n = 1 7 4 0) a n d 8 4. 3 6 %(n = 2 0 7 1), respectively, showing no statistically significant difference. The main reasons for dropping out were postoperative complications(n = 463, 9.7%) and the need for patient observation(n = 299, 6.2%). Among the discharged patients treated using the clinical pathway, the number of patients who were readmitted within 30 d due to postoperative complications was 54(1.1%). In a multivariate analysis, the intraoperative events(OR = 2.558) were the most predictable risk factors for dropping out of the clinical pathway. Additionally, being male(OR = 1.459), advanced age(OR = 1.727), total gastrectomy(OR = 2.444), combined operation(OR = 1.731), and ASA score(OR = 1.889) were significant risk factors affecting the dropout rate from the clinical pathway.CONCLUSION: Laparoscopic gastrectomy appears to be a good indication for the application of a clinical pathway. For successful application, patients with risk factors should be managed carefully. | Hee Sung Kim Sun Oak Kim Byung Sik Kim | 2015 | World Journal of Gastroenterology2015，21，48： | 15 |
| 3 | Aetiology and mechanisms of injury in medial tibial stress syndrome: Current and future developments显示文摘Medial tibial stress syndrome(MTSS) is a debilitating overuse injury of the tibia sustained by individuals whoperform recurrent impact exercise such as athletes and military recruits. Characterised by diffuse tibial anteromedial or posteromedial surface subcutaneous periostitis, in most cases it is also an injury involving underlying cortical bone microtrauma, although it is not clear if the soft tissue or cortical bone reaction occurs first. Nuclear bone scans and magnetic resonance imaging(MRI) can both be used for the diagnosis of MTSS, but the patient's history and clinical symptoms need to be considered in conjunction with the imaging findings for a correct interpretation of the results, as both imaging modalities have demonstrated positive findings in the absence of injury. However, MRI is rapidly becoming the preferred imaging modality for the diagnosis of bone stress injuries. It can also be used for the early diagnosis of MTSS, as the developing periosteal oedema can be identified. Retrospective studies have demonstrated that MTSS patients have lower bone mineral density(BMD) at the injury site than exercising controls, and preliminary data indicates the BMD is lower in MTSS subjects than tibial stress fracture(TSF) subjects. The values of a number of tibial geometric parameters such as cross-sectional area and section modulus are also lower in MTSS subjects than exercising controls, but not as low as the values in TSF subjects. Thus, the balance between BMD and cortical bone geometry may predict an individual's likelihood of developing MTSS. However, prospective longitudinal studies are needed to determine how these factors alter during the development of the injury and to find the detailed structural cause, which is still unknown. Finite element analysis has recently been used to examine the mechanisms involved in tibial stress injuries and offer a promising future tool to understand the mechanisms involved in MTSS. Contemporary accurate diagnosis of either MTSS or a TSF includes a thorough clinical examination to identify signs of bone stress injury and to exclude other pathologies. This should be followed by an MRI study of the whole tibia. The cause of the injury should be established and addressed in order tofacilitate healing and prevent future re-occurrence. | Melanie Franklyn Barry Oakes | 2015 | World Journal of Orthopedics2015，6，8： | 7 |
| 4 | 屯堡村庄中国家建构的谱系仪式显示文摘本文通过对贵州屯堡村庄的地戏仪式的解读,讨论了中国乡村传统仪式的现代重塑这一问题。论文指出,在当代的文化场景中,屯堡村庄的跳神仪式经过一番'化石化'的建构,被重塑为屯堡居民重构自我历史谱系、搬演国家神话、展示权威边界的一种仪式展演;由于当代的地戏表演构成了一个权威边界的商榷场域,屯堡村民在其中既是国家边疆文化政策的对象,又是在文化经济的快速增长中成为自身权力与权威边界的积极商榷者。 | 欧挺木(Timothy Oakes) 汤芸(译) 彭文斌(校) | 2009 | 西南民族大学学报(人文社会科学版)2009，30，9： | 4 |
| 5 | miR-328 Functions as an RNA Decoy to Modulate hnRNP E2 Regulation of mRNA Translation in Leukemic Blasts显示文摘 | Anna M. Eiring Jason G. Harb Paolo Neviani Christopher Garton Joshua J. Oaks Riccardo Spizzo Shujun Liu Sebastian Schwind Ramasamy Santhanam Christopher J. Hickey Heiko Becker Jason C. Chandler Raul Andino Jorge Cortes Peter Hokland Claudia S. Huettner Ra | 2010 | Cell2010，，5： | 2 |
| 6 | 硬质合金和钨重合金的技术进展显示文摘硬质合金和钨重合金(WHA)是钨的两个最重要的市场。几十年来硬质合金已用作刀具、模具和耐磨零件。由于它们被用于我们每天会遇到的制品,因此它们已成为我们的现代工业经济的一个组成部分。尽管它已相当成熟,硬质合金仍然以很快的步伐继续向前发展,这一点已为牌号组成、涂层、几何参数和新的应用的最新发展所证实。这些趋势为这个市场的增长机会提供了一个令人乐观的前景。同样。 | Oakes,JJ 周元杰 | 1995 | 国外难熔金属与硬质材料1995，11，1： | 2 |
| 7 | Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A‐RIPK1‐dependent necroptosis显示文摘 | Sahar A. Saddoughi Salih Gencer Yuri K. Peterson Katherine E. Ward Archana Mukhopadhyay Joshua Oaks Jacek Bielawski Zdzislaw M. Szulc Raquela J. Thomas Shanmugam P. Selvam Can E. Senkal Elizabeth Garrett‐Mayer Ryan M. De Palma Dzmitry Fedarovich Angen Liu | 2012 | EMBO Mol Med2012，，1： | 2 |
| 8 | Mapping of QTL for agronomic traits and kernel characters in durum wheat ( Triticum durum Desf.)显示文摘 | R. M. Patil S. A. Tamhankar M. D. Oak A. L. Raut B. K. Honrao V. S. Rao S. C. Misra | 2013 | Euphytica2013，，1： | 2 |
| 9 | The Insulin Sensitizer,BRL 49653,Reduces Systemic Fatty Acid Supply and Utilization and Tissue Lipid Availability in the Rat 显示文摘 | OAKES N D CAMILLERI S FURLER S M | 1997 | Metabolism1997，46，8： | 1 |
| 10 | Ventral brain stem compression in pediatric and young adult patients with Chiari I malformations 显示文摘 | Grabb PA Mapstone TB Oakes WJ | 1999 | Neurosurgery1999，44，3： | 1 |
| 11 | Cytological and geographical characterization of Hemarthria显示文摘 | Quesenberry K H Oakes A J Jessop D S | 1982 | Euphytica1982，31，2： | 1 |
| 12 | Geological hazards,vulnerability,and risk assessment using GIS:model for Glenwod Springs,Colorado显示文摘 | Mejia-Navarro M Wohl E E Oaks S D | 1994 | Geomorphology1994，10，1： | 1 |
| 13 | Substance P differentially stimulates IL-8 synthesis in human corneal epithelial cells显示文摘 | Tran MT Lausch RN Oakes JE | 2000 | Invest Ophthalmol Vis Sci2000，41，12： | 1 |
| 14 | Systematic renew and modelling of the investigation of acute and chronic chest pain presenting in primary care 显示文摘 | Mant J McManus R J Oakes RA | 2004 | Health Technol Assess2004，8，2： | 1 |
| 15 | Chitosan-zinc-insulin complex incorporated thermosensitive polymer for controlled delivery of basal insulin in vivo显示文摘 | Oak M Singh J | 2012 | J Controlled Release2012，163，2： | 1 |
| 16 | Laparoscopic inguinal hernia repair in the pediatric age group-experience with 437 children 显示文摘 | PARELKAR S V OAK S GUPTA R | 2010 | Pediatr Sur2010，45，4： | 1 |
| 17 | Phase I dose-escalation study of AZD7762, a checkpoint kinase inhibitor, in combination with gemcitabine in US patients with advanced solid tumors显示文摘 | Edward Sausville Patricia LoRusso Michael Carducci Judith Carter Mary F. Quinn Lisa Malburg Nilofer Azad David Cosgrove Richard Knight Peter Barker Sonya Zabludoff Felix Agbo Patricia Oakes Adrian Senderowicz | 2014 | Cancer Chemotherapy and Pharmacology2014，，3： | 1 |
| 18 | Surgical experience in 130 pediatic patients with Chiari I malformation 显示文摘 | Tubbs TS Mcgirt M J Oakes WJ | 2003 | Neurosurgery2003，99，2： | 1 |
| 19 | Estimation of Hole Flange Ability for High Strength Steel Plates 显示文摘 | Hyun D I Oak S M Kang S S | 2002 | Journal of Materials Processing Technology2002，13，013： | 1 |
| 20 | Surgical experience in 130 pediatric patients with Chiari I malformations 显示文摘 | Tubbs RS McGirt M J Oakes WJ | 2003 | J Neurosurg2003，99，2： | 1 |
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