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736篇 您的检索式:作者名="Deepa"
    题名 作者 年代 出处 被引量
1Cancer statistics, 2013显示文摘Rebecca Siegel Deepa Naishadham Ahmedin Jemal 2013CA: A Cancer Journal for Clinicians2013,,1:122
2Plant ABC Transporters Enable Many Unique Aspects of a Terrestrial Plant's Lifestyle显示文摘陆上的植物有更多的 ATP 有约束力的盒子(ABC ) 二~四次 transporter 基因比另外的有机体,包括他们的祖先的 microalgae。最近的研究发现在这些 transporters 怀有变化的植物展出戏剧的显型,许多哪个与发展过程和为干燥土地上的生活必要的功能有关。这些结果建议在进化期间乘并且假定允许植物适应陆上的环境条件的新奇功能的那 ABC transporters。从这个观点在植物 ABC transporters 上检验文学导致了我们建议多样的 ABC transporters 启用了陆上的植物的生活方式的许多唯一、必要的方面,由搬运越过植物的特定的膜的各种各样的混合物。Jae-Ung Hwang Won-Yong Song Daewoong Hong Donghwi Ko Yasuyo Yamaoka Sunghoon Jang Sojeong Yim Eunjung Lee Deepa Khare Kyungyoon Kim Michael Palmgren Hwan Su Yoon Enrico Martinoia Youngsook Lee 2016Molecular Plant2016,9,3:20
3斑马鱼:新型骨骼研究模式生物显示文摘动物模型是揭示人类发育机制、疾病机理和系统功能的重要工具。由于斑马鱼具有胚胎透明、骨骼发育迅速、与人类相关基因和信号通路有高度同源性等特点,已经被成功用于建立骨骼研究模型。本文将介绍斑马鱼骨骼的分类及其形成方式,比较斑马鱼骨骼与哺乳动物骨骼异同,阐述斑马鱼骨骼发育过程中的重要转录因子和信号转导通路,并概述斑马鱼模型骨骼研究的基本方法,最后结合作者经验对斑马鱼这一新型骨骼研究模式生物的科研及开发前景进行展望。李振华 Deepa Alex 徐燕玲 李铭源 2010中药药理与临床2010,26,3:15
4绿茶儿茶酚: 对心血管疾病的防御作用(英文)显示文摘Green tea,Camellia sinensis(Theaceae),a major source of flavonoids such as catechins,has recently shown multiple cardiovascular health benefits through various experimental and clinical studies.These studies suggest that green tea catechins prevent the incidence of detrimental cardiovascular events,and also lower the cardiovascular mortality rate.Catechins present in green tea have the ability to prevent atherosclerosis,hypertension,endothelial dysfunction,ischemic heart diseases,cardiomyopathy,cardiac hypertrophy and congestive heart failure by decreasing oxidative stress,preventing inflammatory events,reducing platelet aggregation and halting the proliferation of vascular smooth muscle cells.Catechins afford an anti-oxidant effect by inducing anti-oxidant enzymes,inhibiting pro-oxidant enzymes and scavenging free radicals.Catechins present anti-inflammatory activity through the inhibition of transcriptional factor NF-κB-mediated production of cytokines and adhesion molecules.Green tea catechins interfere with vascular growth factors and thus inhibit vascular smooth muscle cell proliferation,and also inhibit thrombogenesis by suppressing platelet adhesion.Additionally,catechins could protect vascular endothelial cells and enhance vascular integrity and regulate blood pressure.In this review various experimental and clinical studies suggesting the role of green tea catechins against the markers of cardiovascular disorders and the underlying mechanisms for these actions are discussed.Pooja Bhardwaj Deepa Khanna 2013中国天然药物2013,11,4:10
5Characterization of Ion Contents and Metabolic Responses to Salt Stress of Different Arabidopsis AtHKT1;1 Genotypes and Their Parental Strains显示文摘植物采用几策略在咸度应力下面维持细胞的离子动态平衡,包括由 transmembrane 运输蛋白质的调停的离子流动并且调整由积累 osmolytes 的渗透的压力。HKT (高亲密关系的钾 transporter ) 基因家庭在多样的植物种类包括 Na+ 和 Na+/K+ transporters,与 HKT1;在 Arabidopsis thaliana 的 1 个同样唯一的成员。AtHKT1 的 Cell-type-specific overexpression; 1 被显示了在咸度应力下面阻止射击 Na+ overaccumulation。这里,我们在不同 AtHKT1 的射击和根分析了大量代谢物和元素;在咸度应力前后的 1 遗传型和他们的父母紧张,揭示 AtHKT1 之间的代谢物差别的一种相互的关系; 1 根猛烈的线( hkt1 ; 1 )并且 AtHKT1 ; 1 根 overexpressing 线( E2586 UAS GAL4 : HKT1 ; 1 并且 J2731 *UAS GAL4 : HKT1 ; 1 )。尽管根糖的层次在两 AtHKT1 在盐应力以后被增加; 1 overexpressing 排队, E2586 UAS GAL4 : HKT1 ; osmoprotectants trehalose , gentiobiose ,和 melibiose 的 1 显示出的更高的累积,而 J2731 *UAS GAL4 : HKT1 ;蔗糖和棉白糖的 1 显示出的高水平,与他们的父母线相比,分别地。相反,猛烈的线 hkt1; tricarboxylic 酸(TCA ) 的层次的 1 显示出的猛烈增加骑车在在盐处理以后的射击的中介。这与糖的重要弄空与一致,建议有进以从周期的 C 流出的经常的率的 TCA 周期的碳流入的增加的率,它可能被需要在盐应力期间支持植物幸存。用关联分析,我们识别了在 Na+ 内容和几糖之间的协会,建议糖新陈代谢的那条规定在对咸度应力的植物回答是重要的。Camilla B. Hill Deepa Jha Antony Bacic Mark Tester Ute Roessner 2013Molecular Plant2013,6,2:8
6Cancer statistics, 2013显示文摘Rebecca Siegel Deepa Naishadham Ahmedin Jemal 2013CA: A Cancer Journal for Clinicians2013,,1:8
7Cancer statistics for Hispanics/Latinos, 2012显示文摘Rebecca Siegel Deepa Naishadham Ahmedin Jemal 2012CA: A Cancer Journal for Clinicians2012,,5:5
8国内观鸟旅游研究综述显示文摘观鸟旅游作为生态旅游的一种重要表现形式,对经济、社会、环境保护等具有重要意义。随着观鸟旅游的发展,国内观鸟旅游的研究逐渐增多。文章整理了国内观鸟旅游研究文献,经过筛选确定了97篇文章作为研究对象,采用定量与定性研究结合的方式,总结了国内观鸟旅游的研究内容和方向。资源分析与旅游开发是国内观鸟旅游研究的重要内容,观鸟者行为研究、观鸟教育、观鸟旅游发展对策分析在观鸟旅游研究中也涉及较多,观鸟旅游的研究在不同方面存在较大差异性,以及地域空白性。加强观鸟旅游的研究,弥补地域空白性对观鸟旅游的发展有重要意义,文章在综述分析的基础上,预测了观鸟旅游的发展方向和研究趋势。肖乾丽 杨建美 Deepa Basnet 岳茂伟 2019河北旅游职业学院学报2019,24,1:5
9Pancreatic intraepithelial neoplasia arising from an ectopic pancreas in the small bowel显示文摘BACKGROUND: Ectopic pancreatic tissue is relatively uncommon, and is characterized as pancreatic tissue with no contact with the normal pancreas, and with its own ductal system and blood supply. It is usually asymptomatic, and can be incidentally diagnosed by conventional imaging studies.METHOD: A 69-year-old woman with a prior history of bilateral breast carcinoma presented with ectopic pancreatic intraepithelial neoplasia (PanI N) that was identified incidentally in the small bowel during an oncological resection of a synchronous primary pancreatic adenocarcinoma, and renal cell carcinoma.RESULTS: The patient underwent subtotal pancreatectomy with splenectomy, regional lymphadenectomy, radical left nephrectomy, and small bowel resection with primary anastomosis of ectopic Pan IN-2. She had an uneventful hospitalization and was discharged home on postoperative day 7.CONCLUSIONS: The occurrence of ectopic PanI N is extremely unusual with only few cases previously reported in the literature. The need for negative margins after surgical resection of ectopic PanI N lesions remains controversial.Francisco Igor Macedo Deepa Taggarshe Tafadzwa Makarawo Barry Herschman Michael J Jacobs 2014Hepatobiliary & Pancreatic Diseases International2014,13,6:4
10The role of dynamic contrast-enhanced and diffusion weighted magnetic resonance imaging in the female pelvis显示文摘Evis Sala Andrea Rockall Deepa Rangarajan Rahel A. Kubik-Huch 2010European Journal of Radiology2010,,3:3
11Targeting the Immune System in the Treatment of Non-Small-Cell Lung Cancer显示文摘Deepa Rangachari Julie R. Brahmer 2013Current Treatment Options in Oncology2013,,4:2
12Novel powellite-based red-emitting phosphors: CaLa 1? x NbMoO 8 : x Eu 3+ for white light emitting diodes显示文摘Mariyam Thomas P. Prabhakar Rao M. Deepa M.R. Chandran Peter Koshy 2008Journal of Solid State Chemistry2008,,1:2
13Novel predictors of permanent pacemaker implantation following transcatheter aortic valve replacement显示文摘BACKGROUND Conduction and rhythm abnormalities requiring permanent pacemakers(PPM)are short-term complications following transcatheter aortic valve replacement(TAVR),and their clinical outcomes remain conflicting.Potential novel predictors of post-TAVR PPM,like QRS duration,QTc prolongation,and supraventricular arrhythmias,have been poorly studied.AIM To evaluate the effects of baseline nonspecific interventricular conduction delay and supraventricular arrhythmia on post-TAVR PPM requirement and determine the impact of PPM implantation on clinical outcomes.METHODS RESULTS Out of the 357 patients that met inclusion criteria,the mean age was 80 years,188(52.7%)were male,and 57(16%)had a PPM implantation.Baseline demographics,valve type,and cardiovascular risk factors were similar except for type II diabetes mellitus(DM),which was more prevalent in the PPM cohort(59.6%vs 40.7%;P=0.009).The PPM cohort had a significantly higher rate of pre-procedure right bundle branch block,prolonged QRS>120 ms,prolonged QTc>470 ms,and supraventricular arrhythmias.There was a consistently significant increase in the odds ratio(OR)of PPM implantation for every 20 ms increase in the QRS duration above 100 ms:QRS 101-120[OR:2.44;confidence intervals(CI):1.14-5.25;P=0.022],QRS 121-140(OR:3.25;CI:1.32-7.98;P=0.010),QRS 141-160(OR:6.98;CI:3.10-15.61;P<0.001).After model adjustment for baseline risk factors,the OR remained significant for type II DM(aOR:2.16;CI:1.18-3.94;P=0.012),QRS>120(aOR:2.18;CI:1.02-4.66;P=0.045)and marginally significant for supraventricular arrhythmias(aOR:1.82;CI:0.97-3.42;P=0.062).The PPM cohort had a higher adjusted OR of heart failure(HF)hospitalization(aOR:2.2;CI:1.1-4.3;P=0.022)and nonfatal myocardial infarction(MI)(aOR:3.9;CI:1.1-14;P=0.031)without any difference in mortality(aOR:1.1;CI:0.5-2.7;P=0.796)at one year.CONCLUSION Pre-TAVR type II DM and QRS duration>120,regardless of the presence of bundle branch blocks,are predictors of post-TAVR PPM.At 1-year post-TAVR,patients with PPM have higher odds of HF hospitalization and MI.Somto Nwaedozie Haibin Zhang Javad Najjar Mojarrab Param Sharma Paul Yeung Peter Umukoro Deepa Soodi Rachel Gabor Kelley Anderson Romel Garcia-Montilla 2023World Journal of Cardiology2023,15,11:2
14Management of enterocutaneous fistulae:A 10 years experience显示文摘AIM:To compare the outcomes of conservative vs surgical treatment of enterocutaneous fistulae(ECF) in a community teaching hospital over a decade.METHODS:All cases of ECF between 1997 and 2007 were reviewed for management strategy.RESULTS:Of the 83 patients with ECF,60(72%) were postoperative.Sixty-six patients(79.5%) were treated initially with conservative measures.Eighteen patients failed to respond to conservative treatment and required later(secondary) exploration;this group consisted of an equal number of low vs high output fistulae.Seventeen(20.5%) patients underwent initial(primary) def initivesurgery secondary to anastomotic leak and peritonitis.Surgical procedures included resection of ECF with anastomosis(24),exclusion(6) and direct-drainage(4).No signif icant difference was seen in the recurrence rate for conservative(10%) vs operative-treatment(20%).role as an initial management in both low and high output fistulae.In selective cases only,early primary exploration is recommended.Deepa Taggarshe Daniel Bakston Michael Jacobs Alasdair McKendrick Vijay K Mittal 2010World Journal of Gastrointestinal Surgery2010,2,7:2
15Effect of copper nanoparticles exposure in the physiology of the common carp(Cyprinus carpio):Biochemical,histological and proteomic approaches显示文摘Copper nanoparticles(Cu-NPs)are serious water pollutants but their impact in teleosts performance remains poorly understood.In the present study,we have exposed juvenile carps(Cyprinus carpio),a freshwater teleost edible in India to two different doses(20 and 100 mg/L)of Cu-NPs for seven days.The doses selected were eco-relevant considering the contamination levels of certain water resources.The results indicated that the activity oxidative stress enzymes catalase,superoxide dismutase,and glutathione-S-transferase were significantly increased in the kidney,liver and gills of the treated groups when compared to control.Histological analysis revealed that after exposure,disruption of the secondary lamellae of gills,liver damage with pyknotic nuclei and structural disarray of the kidney occurred.Proteomic analysis of the liver showed down-regulation of several proteins including the ferritin heavy chain,rho guanine nucleotide exchange factor 17-like,cytoglobin-1 and up-regulation of diphosphomevalonate decarboxylase and selenide&water dikinase-1.Taken together,the results of suggest that short-term exposure of juvenile carp to Cu-NPs causes oxidative stress and impart serious deleterious effects in the tissues which may affect fish growth and development.Yugantak Raj Gupta Durai Sellegounder Monica Kannan Seetharam Deepa Balasubramanian Senthilkumaran Yaraguntappa Basavaraju 2016Aquaculture and Fisheries2016,1,1:2
16中国实生和无性系苹果砧木及其杂交后代矮化基因型分子鉴定显示文摘【目的】利用已开发的矮化性状分子标记(Dw1/Dw2)筛选中国实生和自育无性系苹果砧木,探明各个砧木品种的矮化基因型,为苹果砧木育种工作中亲本选择及矮化分子辅助育种提供帮助。【方法】以不同地区采集的24份中国实生和自育的无性系苹果砧木、147份新疆野苹果(李2-3)בM9’和345份山荆子(野1-2)בM9’杂交后代单株的叶片DNA为模板,以矮化砧木‘M9’‘M116’和‘MM106’为对照,利用已经开发的Dw1和Dw2矮化标记的SSR引物进行PCR扩增,然后用毛细管电泳检测PCR产物,分析确定各个样品的矮化基因型。【结果】在24份中国苹果砧木中鉴定出8份携带Dw1矮化基因,5份携带Dw2矮化基因,3个自育杂交品种同时携带Dw1和Dw2矮化基因;新疆野苹果(李2-3)בM9’组合的147个杂种实生苗中有48株携带Dw1矮化基因,14株同时携带Dw1和Dw2基因,山荆子(野1-2)בM9’的345个杂交后代中仅有11个单株携带Dw1基因型,其余单株均不携带任一矮化基因。【结论】试验中检测的八棱海棠(房2-3)、山荆子(野1-2)和平邑甜茶(野2-22)等中国常用实生砧木均不携带Dw1或Dw2基因,仅新疆野苹果(李2-3)中含有Dw2矮化基因;中国自育的杂交砧木品种中,以‘M9’等矮化品种为亲本的后代大多携带Dw1或Dw2;双亲都含有矮化基因的杂交组合后代能获得更多的携带矮化基因的单株。张恒涛 BUS Vincent G.M. 张亚茹 王欢 王美丽 BOWATTE Deepa GARDINER Susan E. CHAGNE David KIRK Chris KUMAR Satish 王大江 张瑞萍 周喆 YAO Jia-Long 阎振立 2020果树学报2020,37,12:2
17PCT as a Prognostic Marker in Cardiac Patients with Neutropenic Sepsis: Two Case Reports显示文摘Neelima Verma Shaloo Kapoor Deepa Rao Siddhartha Sharma Anita Arora 2014Indian Journal of Clinical Biochemistry2014,,1:2
18Risk for esophageal neoplasia in B arrett’s esophagus patients with mucosal changes indefinite for dysplasia显示文摘Bela Horvath Prabhdeep Singh Hao Xie Prashanthi N Thota Daniela S Allende Rish K Pai Deepa T Patil Thomas P Plesec John R Goldblum Xiuli Liu 2015J Gastroenterol Hepatol2015,,:2
19Vacuolating Cytotoxin and Variants in Atg16L1 That Disrupt Autophagy Promote Helicobacter pylori Infection in Humans显示文摘Deepa Raju Seamus Hussey Michelle Ang Mauricio R. Terebiznik Michal Sibony Esther Galindo–Mata Vijay Gupta Steven R. Blanke Alberto Delgado Judith Romero–Gallo Mahendra Singh Ramjeet Heidi Mascarenhas Richard M. Peek Pelayo Correa Cathy Streutker Georgina 2012Gastroenterology2012,,5:2
20Miscibility and phase separation in SAN/PMMA blends investigated by positron lifetime measurements显示文摘Kumaraswamy G N Ranganathaiah C Deepa U M V 2006European Polymer Journal2006,42,10:1
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