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| 1 | Therapeutic Efficacy of Neurostimulation for Depression:Techniques, Current Modalities, and Future Challenges显示文摘Depression is the most prevalent debilitating mental illness; it is characterized as a disorder of mood,cognitive function, and neurovegetative function. About one in ten individuals experience depression at some stage of their lives. Antidepressant drugs are used to reduce the symptoms but relapse occurs in *20% of patients. However,alternate therapies like brain stimulation techniques have shown promising results in this regard. This review covers the brain stimulation techniques electroconvulsive therapy,transcranial direct current stimulation, repetitive transcranial magnetic stimulation, vagus nerve stimulation, and deep brain stimulation, which are used as alternatives to antidepressant drugs, and elucidates their research and clinical outcomes. | Hafsah Akhtar Faiza Bukhari Misbah Nazir Muhammad Nabeel Anwar Adeeb Shahzad | 2016 | Neuroscience Bulletin2016，32，1： | 8 |
| 2 | Copper as a single metal atom based photo-,electro-,and photoelectrochemical catalyst decorated on carbon nitride surface for efficient CO_(2) reduction:A review显示文摘The processes of photocatalytic CO_(2) reduction(pCO_(2)R)and electrochemical CO_(2) reduction(ECO_(2)R)have attracted considerable interest owing to their high potential to address many environmental and energy-related issues.In this aspect,a single Cu atom decorated on a carbon nitride(CN)surface(Cu-CN)has gained increasing popularity because of its unique advantages,such as excellent atom utilization and ultrahigh catalytic activity.CN-particularly graphitic CN(g-C_(3)N_(4))-is a photo-and electrocatalyst and used as an important support material for single Cu atom-based catalysts.These key functions of Cu-CN-based catalysts can improve the catalytic performance and stability in the pCO_(2)R and ECO_(2)R during the application process.In this review,we focus on Cu as a single metal atom decorated on CN for efficient photoelectrochemical CO_(2) reduction(pECO_(2)R),where ECO_(2)R increases the electrocatalytic active area and promotes electron transfer,while pCO_(2)R enhances the surface redox reaction by efficiently using photogenerated charges and offering integral activity as well as an active interface between Cu and CN.Interactions of single Cu atom-based photo-,electro-,and photoelectrochemical catalysts with g-C_(3)N_(4) are discussed.Moreover,for a deeper understanding of the history of the development of pCO_(2)R and ECO_(2)R,the basics of CO_(2) reduction,including pCO_(2)R and ECO_(2)R over g-C_(3)N_(4),as well as the structural composition,characterization,unique design,and mechanism of a single atom site are reviewed in detail.Finally,some future prospects and key challenges are discussed. | Lulu Li Israr Masood ul Hasan Farwa Ruinan He Luwei Peng Nengneng Xu Nabeel Khan Niazi Jia-Nan Zhang Jinli Qiao | 2022 | Nano Research Energy2022，1，2： | 7 |
| 3 | Albumin as a prognostic marker for ulcerative colitis显示文摘AIM To evaluate the role of albumin at the time of ulcerative colitis(UC) diagnosis in predicting the clinical course of disease.METHODS Nationwide cohort of patients with newly diagnosed UC in the Veterans Affairs health care system was identified and divided into two categories: hypoalbuminemia(i.e.,≤ 3.5 gm/dl) or normal albumin levels(i.e.,> 3.5 gm/dl) at the time of UC diagnosis. The exposure of interest was presence of hypoalbuminemia defined asalbumin level ≤ 3.5 g/dl at the time of UC diagnosis. Patients were then followed over time to identify the use of ≥ 2 courses of corticosteroids(CS),thiopurines,anti-TNF medications and requirement of colectomy for UC management. RESULTS The eligible study cohort included 802 patients,but 92(11.4%) patients did not have their albumin levels checked at the time of UC diagnosis,and they were excluded. A total of 710 patients,who had albumin levels checked at time of UC diagnosis,were included in our study. Amongst them,536 patients had a normal albumin level and 174 patients had hypoalbuminemia. Patients with hypoalbuminemia at diagnosis had a higher likelihood of ≥ 2 courses of CS use(adjusted HR = 1.7,95%CI: 1.3-2.3),higher likelihood of thiopurine or anti-TNF use(adjusted HR = 1.72,95%CI: 1.23-2.40) than patients with normal albumin level at diagnosis. There was a trend of higher likelihood of colectomy in hypoalbuminemic patients,but it was not statistically significant(Adjusted HR = 1.7,95%CI: 0.90-3.25).CONCLUSION Hypoalbuminemia at disease diagnosis can serve as a prognostic marker to predict the clinical course of UC at the time of diagnosis. | Nabeel Khan Dhruvan Patel Yash Shah Chinmay Trivedi Yu-Xiao Yang | 2017 | World Journal of Gastroenterology2017，23，45： | 6 |
| 4 | 槟榔子中抗血小板聚集及抑制乙酰胆碱酯酶活性的有效成分(英文)显示文摘目的:研究槟榔子(Areca catechu)粗提取物中所含的抗血小板聚集及抑制乙酰胆碱酯酶活性的有效成分及其作用机制。方法:使用70%甲醇水溶液对槟榔子进行粗提取。使用生物发光血小板凝集仪在富血小板血浆中测定槟榔子粗提取物的抗血小板聚集作用,使用分光光度计在试管内测定槟榔子粗提取物对乙酰胆碱酯酶活性的抑制作用。检测槟榔子中的多种化合物以测定槟榔子中抗血小板聚集及抑制乙酰胆碱酯酶活性的有效成分。结果:槟榔子粗提取物能够抑制花生四烯酸、二磷酸腺苷、血小板活化因子、肾上腺素及钙离子载体引起的血小板聚集,尤其对二磷酸腺苷及钙离子载体引起的血小板聚集的抑制最为明显;槟榔子粗提取物能够显著抑制乙酰胆碱酯酶的活性。在所检测的槟榔子所含化合物中,只有儿茶素对肾上腺素引起的血小板聚集有显著的抑制作用,而这种抑制作用显著弱于槟榔子粗提取物,提示槟榔子中的其他成分参与了这种抑制作用;鞣酸、没食子酸、薯蓣皂苷元和异去甲槟榔次碱能够抑制乙酰胆碱酯酶的活性,其中鞣酸的抑制作用强于槟榔子粗提取物。结论:槟榔子中含有抗血小板聚集及抑制乙酰胆碱酯酶活性的有效成分,而发挥这些功效的确切成分有待进一步的研究证实。 | Muhammad Nabeel Ghayur Syed Faraz Kazim Huma Rasheed Asaad Khalid Maliha Iqbal Jumani Muhammad Iqbal Choudhary Anwarul Hassan Gilani | 2011 | 中西医结合学报2011，9，6： | 4 |
| 5 | LES of rotating film-cooling performance in a 1-1/2 turbine stage显示文摘The large eddy simulation method was employed to investigate the film-cooling performance in a low-speed rotor blade of a 1-1/2 turbine stage.The rotor blade height and axial chord length were 99 mm and 124.3 mm,respectively.Two rows of film holes were placed on the rotor blade surface,one each on the pressure and suction surfaces.Each row had three cylindrical film holes with a diameter of 4 mm and a tangential injection angle of 28°on the pressure side and 361 on the suction side.The Reynolds number was fixed at Re=1.92×10^(5)and the coolant-to-mainstream density ratio(DR)was about 2.0.Simulations were carried out for three different rotating speeds of 1800,2100,and 2400 rpm with the blowing ratio(BR)varying from 0.3 to 3.0.The commercial CFD code STAR-CCM+was used to run the simulations using the WALE subgrid-scale model for modelling the turbulence.The results show that on the pressure side,the film coverage and filmcooling effectiveness decrease with increasing rotation number(Ro)and increase with increasing blowing ratio(BR).A higher Ro and lower BR result in a stronger film deflection.The film injection with higher BR produces better film attachment.The film deflects centrifugally where the deflection becomes greater with increasing Ro.On the suction side,the film coverage and film-cooling effectiveness increase with increasing either Ro or BR and a centripetal deflection of the film is observed.The deflection of the film path could be amplified by either increasing the Ro at a constant BR or decreasing the BR at a constant Ro.Increasing the rotation weakens the film deflection towards the hub on the suction surface.Overall,it was found that both rotation number and blowing ratio play significant roles in determining the film-cooling effectiveness distributions of the rotor blade surface. | Nabeel Al-Zurfi Adel Nasser | 2019 | Propulsion and Power Research2019，8，2： | 3 |
| 6 | Risk of Lymphoma in Patients with Ulcerative Colitis Treated with Thiopurines—a Nationwide Retrospective Cohort Study显示文摘 | Nabeel Khan Ali M. Abbas Gary R. Lichtenstein Edward V. Loftus Lydia A. Bazzano | 2013 | Gastroenterology2013，，： | 2 |
| 7 | Pancreatic Adenocarcinoma显示文摘 | David P. Ryan Theodore S. Hong Nabeel Bardeesy | 2014 | The New England Journal of Medicine2014，，： | 2 |
| 8 | Acute ischaemic stroke interventions: large vessel occlusion and beyond显示文摘Care for acute ischaemic stroke is one of the most rapidly evolving fields due to the robust outcomes achieved by mechanical thrombectomy.Large vessel occlusion(LVO)accounts for up to 38%of acute ischaemic stroke and comes with devastating outcomes for patients,families and society in the pre-intervention era.A paradigm shift and a breakthrough brought mechanical thrombectomy back into the spotlight for acute ischaemic stroke;this was because five randomised controlled trials from several countries concluded that mechanical thrombectomy for acute stroke offered overwhelming benefits.This review article will present a comprehensive overview of LVO management,techniques and devices used,and the future of stroke therapy.In addition,we review our institution experience of mechanical thrombectomy for posterior and distal circulation occlusion. | Ahmad Sweid Batoul Hammoud Sunidhi Ramesh Daniella Wong Tyler D Alexander Joshua Harrison Weinberg Maureen Deprince Jaime Dougherty Dimitri Jean-Mickael Maamari Stavropoula Tjoumakaris Hekmat Zarzour Michael R Gooch Nabeel Herial Victor Romo David M Hasan Robert H Rosenwasser Pascal Jabbour | 2020 | Stroke & Vascular Neurology2020，5，1： | 2 |
| 9 | A numerical study of anti-vortex film-cooling holes designs in a 1-1/2 turbine stage using LES显示文摘The primary focus of the present study is to investigate the impact of anti-vortex holes design on the film-cooling performance in a film-cooled rotor blade model using the large eddy simulation method(LES).One row of the film holes was positioned on the pressure surface of the rotor blade.This row had three cylindrical holes(the main hole in the present study)with a diameter(D)of 4 mm and a tangential injection angle of 28 deg.Each main hole supplemented with the addition of two symmetrical side holes(anti-vortex holes),which branch out from the same main hole.Three positions for the anti-vortex side holes were considered;namely:upstream to the outlet of the main hole;in line with the main hole;and downstream of the main hole.The Reynolds number was fixed at Re Z 1.92105 and the speed of the rotor blade was taken to be 1800 rpm.The blowing ratio varied from 1.0 to 5.0 and the density ratio of coolant to mainstream was 2.0.Compared to the base hole,the film cooling performance of the all anti-vortex cases showed obvious improvement at all blowing ratios.The middle stream side holes and downstream side holes each demonstrated good film cooling performance at all blowing ratios,while the upstream side holes perform well only at a lower blowing ratio.The presence of side holes can restrain the CRVP(counter rotating vortex pairs)intensity of the main hole and reduce the coolant lift-off,improving the film coverage and film cooling effectiveness.The downstream side holes can perform better in reducing the CRVP intensity. | Nabeel Al-Zurfi Ali Turan Adel Nasser Ahmed Alhusseny | 2019 | Propulsion and Power Research2019，8，4： | 2 |
| 10 | Prevalence and Predictors of Low Bone Mineral Density in Males With Ulcerative Colitis显示文摘 | Nabeel Khan Ali M. Abbas Rawaa M. Almukhtar Amna Khan | 2013 | The Journal of Clinical Endocrinology & Metabolism2013，，6： | 2 |
| 11 | NEURO FUZZY MODEL FOR PREDICTING THE DYNAMIC CHARACTERISTICS OF BEAMS显示文摘An adaptive neuro-fuzzy inference system(ANFIS) is introduced to predict the dynamic behavior of beams. The effects of axial forces and large displacements are considered in the analysis. A database of tests for the dynamic characteristics of beams is developed from the experimental tests. The responses of nonlinear vibration force for the single and multiple-stepped beams are calculated from the finite element method(FEM), experimental tests and neuro-fuzzy model for comparison. The neuro-fuzzy model provides a general framework for the combination of neural networks and fuzzy logic. It is more flexible with more options of incorporating the fuzzy nature of the real-world system and is an useful estimation tool for the dynamic characteristics of beams. Therefore, ANFIS can be a useful tool for dynamic behaviour analysis of multiple-stepped beams subjected to axial loads and large displacement. | Imad O.Bachi Nabeel Abdulrazzaq Zeng He | 2014 | Acta Mechanica Solida Sinica2014，27，1： | 2 |
| 12 | Cardiovascular effects of ginger aqueous extract and its phenolic constituents are mediated through multiple pathways显示文摘 | Muhammad Nabeel Ghayur Anwarul Hassan Gilani Maria B. Afridi Peter J. Houghton | 2005 | Vascular Pharmacology2005，，4： | 1 |
| 13 | Ready, Set, Go: The EGF Receptor at the Pancreatic Cancer Starting Line显示文摘 | Rushika M. Perera Nabeel Bardeesy | 2012 | Cancer Cell2012，，： | 1 |
| 14 | Space-muhiplexed Optical Scanner Source 显示文摘 | Riza Nabeel A Yaqoob Zahid | 2004 | Applied Optics2004，43，5： | 1 |
| 15 | Outcomes of Endoscopic and Percutaneous Drainage of Pancreatic Fluid Collections Arising after Pancreatic Tail Resection显示文摘 | Nabeel Azeem Todd H. Baron Mark D. Topazian Ning Zhong Chad J. Fleming Michael L. Kendrick | 2012 | Journal of the American College of Surgeons2012，，2： | 1 |
| 16 | Enhancing Hematopoietic Stem Cell Transplantation Efficacy by Mitigating Oxygen Shock显示文摘 | Charlie R. Mantel Heather A. O’Leary Brahmananda R. Chitteti XinXin Huang Scott Cooper Giao Hangoc Nickolay Brustovetsky Edward F. Srour Man Ryul Lee Steven Messina-Graham David M. Haas Nadia Falah Reuben Kapur Louis M. Pelus Nabeel Bardeesy Julien Fitama | 2015 | Cell2015，，7： | 1 |
| 17 | A prospective randomized, controlled trial comparing synchronized nasal intermittent positive pressure ventilation versus nasal continuous positive airway pressure as modes of extubation显示文摘 | Nabeel K Nancy B John H | 2001 | Pediatrics2001，108，1： | 1 |
| 18 | Application of solar assisted heating and desiccant cooling systems for a domestic building 显示文摘 | Khalid Joudi A Nabeel Dhaidan S | 2001 | Energy Conversion and Management2001，42，： | 1 |
| 19 | Foundation for low loss fiber gradient index lens pair coupling with the self-imaging mechanism显示文摘 | Martin Van Buren Nabeel A Riza | 2003 | Applied Optics2003，42，3： | 1 |
| 20 | A liquid lens-based on broadband variable fiber optical attenuator 显示文摘 | A R Syed A R Nabeel | 2009 | Opt Commun2009，282，7： | 1 |
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