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| 1 | Spinal cord injury in the setting of traumatic thoracolumbar fracture is not reliably associated with increased risk of associated intra-abdominal injury following blunt trauma:An analysis of a National Trauma Registry database显示文摘Purpose:There is a common opinion that spinal fractures usually reflect the substantial impact of injuries and therefore may be used as a marker of significant associated injuries,specifically for intra-abdominal injury(IAI).The impact of concomitant spinal cord injury(SCI)with the risk of associated IAI has not been well clarified.The aim of this study was to evaluate the incidence and severity of IAIs in patients suffering from spinal fractures with or without SCI.Methods:A retrospective cohort study using the Israeli National Trauma Registry was conducted.Patients with thoracic,lumbar and thoracolumbar fractures resulting from blunt mechanisms of injury from January 1,1997 to December 31,2018 were examined,comparing the incidence,severity and mortality of IAIs in patients with or without SCI.The collected variables included age,gender,mechanism of injury,incidence and severity of the concomitant IAIs and pelvic fractures,abbreviated injury scale,injury severity score,and mortality.Statistical analysis was performed using GraphPad InStat?Version 3.10,with Chi-square test for independence and two sided Fisher’s exact probability test.Results:Review of the Israeli National Trauma Database revealed a total of 16,878 patients with spinal fractures.Combined thoracic and lumbar fractures were observed in 1272 patients(7.5%),isolated thoracic fractures in 4967 patients(29.4%)and isolated lumbar fractures in 10,639 patients(63.0%).The incidence of concomitant SCI was found in 4.95%(63/1272),7.65%(380/4967)and 2.50%(266/10639)of these patients,respectively.The overall mortality was 2.5%,proving higher among isolated thoracic fracture patient than among isolated lumbar fracture counterparts(11.3%vs.4.6%,p<0.001).Isolated thoracic fractures with SCI were significantly more likely to die than non-SCI counterparts(8.2%vs.3.1%,p<0.001).There were no differences in the incidence of IAIs between patients with or without SCI following thoracolumbar fractures overall or in isolated thoracic fractures;although isolated lumbar fractures patients with SCI were more likely to have renal(3.4%vs.1.6%,p=0.02)or bowel injuries(2.3%vs.1.0%,p=0.04)than the non-SCI counterparts.Conclusion:SCI in the setting of thoracolumbar fracture does not appear to be a marker for associated IAI.However,in a subset of isolated lumbar fractures,SCI patient is associated with increased risks for renal and bowel injury. | Veacheslav Zilbermints Yehuda Hershkovitz Kobi Peleg Joseph J.Dubose Adi Givon David Aranovich Mickey Dudkiewicz Israeli Trauma Group Boris Kessel | 2021 | Chinese Journal of Traumatology2021,24,3: | 9 |
| 2 | Clinical scale expansion of cytokine-induced killer cells is feasible from healthy donors and patients with acute and chronic myeloid leukemia at various stages of therapy显示文摘 | Madelaine Niam Yeh-Ching Linn Stephanie Fook Chong Tsyr-Jong Lim Sixian Chu Alicia Choong Hao-Xiang Yong Garnet Suck Marieta Chan Mickey Koh | 2011 | Experimental Hematology2011,,9: | 2 |
| 3 | Medical student depression and its correlates across three international medical schools显示文摘BACKGROUND Medical students have high rates of depression, anxiety, and burnout that have been found to affect their empathy, professional behaviors, and performance as a physician. While studies have examined predictors for burnout and depression in the United States (US), no study, to our knowledge, has compared depression in medical students cross-culturally, or has attempted to examine the effect of factors influencing rates including burnout, exercise, stress, unmet mental health needs, and region. AIM To examine rates of depression in three international cohorts of medical students, and determine variables that may explain these differences. METHODS Convenience samples of medical students from three countries (US, China, and a Middle Eastern country whose name remains anonymous per request from the school) were surveyed in this observational study. Using the Patient Health Questionnaire-2 (PHQ-2) and a modified Maslach Burnout Inventory, depression and burnout were examined among medical students from the three cohorts (n = 473). Chi-square test and analysis of variance were used to examine differences in demographics, behavioral, and psychological variables across these three schools to identify potentially confounding descriptive characteristics. Analysis of covariance compared depression and the emotional exhaustion component of burnout identified through Principal Component Analysis across countries. Multiple linear regression was used to analyze the impact of demographic, behavioral, and psychological variables on screening positive for depression. RESULTS Medical students from the Middle Eastern country had the highest rates of positive depression screens (41.1%), defined as a PHQ-2 score of ≥ 3, followed by China (14.1 %), and then the US (3.8%). More students in the Middle Eastern school had unmet mental health needs (50.8%) than at the medical school in China (34.8%) or the school in the US (32.8%)(Pearson chi-square significance < 0.05). Thus, PHQ-2 scores were adjusted for unmet mental health needs;however, the Middle Eastern country continued to have the highest depression. Adjusting for PHQ-2 score, medical students from the US scored the highest on emotional exhaustion (a measure of burnout). Demographic variables did not significantly predict medical student depression;however, lack of exercise, unmet mental health needs, stress, and emotional exhaustion predicted nearly half of depression in these cohorts. In comparison to the US, coming from the Middle Eastern country and China predicted higher levels of depression. CONCLUSION Depression rates differ in three international cohorts of medical students. Measured factors contributed to some observed differences. Identifying sitespecific prevention and intervention strategies in medical student mental health is warranted. | Jessica A Gold Xinran Hu Gan Huang Wan-Zhen Li Yi-Fan Wu Shan Gao Zhe-Ning Liu Mickey Trockel Wan-Zhen Li Yi-Fan Wu Shan Gao Zhe-Ning Liu Robert M Rohrbaugh Kirsten M Wilkins | 2019 | World Journal of Psychiatry2019,9,4: | 2 |
| 4 | Endoscopic Retrograde Cholangiopancreatography Gut Perforations: When to Wait! When to Operate!显示文摘 | Morgan Katherine A Fontenot Bennett B Ruddy Jean M Mickey Suzanne Adams David B | 2009 | The American Surgeon2009,,6: | 2 |
| 5 | IκB Kinase Promotes Tumorigenesis through Inhibition of Forkhead FOXO3a显示文摘 | Mickey C.-T Hu Dung-Fang Lee Weiya Xia Leonard S Golfman Fu Ou-Yang Jer-Yen Yang Yiyu Zou Shilai Bao Norihisa Hanada Hitomi Saso Ryuji Kobayashi Mien-Chie Hung | 2004 | Cell2004,,2: | 2 |
| 6 | Automotive Supplier Parks: An Imperative for Build-to-order? 显示文摘 | Mickey Howard Joe Miemczyk Andrew Graves | 2006 | Journal of Purchasing & Supply Management2006,,12: | 1 |
| 7 | Intracoronary injection of basic fibroblast growth factor enhances angiogenesis in infracted swine myocardium显示文摘 | Mickey S Amir B | 1993 | J Am Coll Cardiol1993,22,7: | 1 |
| 8 | Estimation of error rates in discriminant analysis显示文摘 | Lachenbruch P A Mickey M R | 1968 | Technometrics1968,10,: | 1 |
| 9 | New insights into the nature of the wool fibre surface显示文摘 | Mickey Huson David Evans Jeff Church | 2008 | Journal of Structural Biology2008,163,: | 1 |
| 10 | Neurosurgical applications of the cyanoacrylate adhensives显示文摘 | Mickey BE Samson D | 1981 | Clin Neurosurg1981,28,4: | 1 |
| 11 | A combined frontotemporal and lateral infratemporal fossa approach to the skull bass 显示文摘 | Close L Schaefer S | 1988 | J Neurosurg1988,68,: | 1 |
| 12 | Outpatient evaluation of obesity in adults and children显示文摘 | Mickey E. Denen MD Dr. James V. Hennessey MD Ronald J. Markert PhD | 1993 | Journal of General Internal Medicine1993,,5: | 1 |
| 13 | Relationship of GnRH‐stimulated LH release to episodic LH secretion and baseline endocrine‐metabolic measures in women with polycystic ovary syndrome显示文摘 | KetanPatel Mickey S.Coffler Michael H.Dahan Pamela J.Malcom ReenaDeutsch R. JeffreyChang | 2003 | Clinical Endocrinology2003,,1: | 1 |
| 14 | Frequency characteristics of wavelets显示文摘 | Chethan Parameswariah Mickey Cox | 2002 | IEEE Transactions on Power Delivery2002,17,3: | 1 |
| 15 | The Haleakala Stokes polarimeter显示文摘 | D. L. Mickey | 1985 | Solar Physics1985,,2: | 1 |
| 16 | The derivation of vector magnetic fields from stokes profiles: Integral versus least squares fitting techniques显示文摘 | R. S. Ronan D. L. Mickey F. Q. Orrall | 1982 | Solar Physics (-)1982,,1: | 1 |
| 17 | Human chromosome 21-derived miRNAs are overexpressed in down syndrome brains and hearts显示文摘 | Donald E. Kuhn Gerard J. Nuovo Mickey M. Martin Geraldine E. Malana Adam P. Pleister Jinmai Jiang Thomas D. Schmittgen Alvin V. Terry Katheleen Gardiner Elizabeth Head David S. Feldman Terry S. Elton | 2008 | Biochemical and Biophysical Research Communications2008,,3: | 1 |
| 18 | Neurosurgical applications of the cyanoacrylatead hensives显示文摘 | Mickey BE Samson D | 1981 | Clin Neurosurg1981,28,4: | 1 |
| 19 | Optimizing systemic therapy for metastatic renal cell carcinoma beyond the first-line setting显示文摘 | De Velasco G Hamieh L Mickey S | 2015 | Urol Oncol2015,33,12: | 1 |
| 20 | Surgical management of nasopharyngeal angiofibroma involving the cavernous sinus显示文摘 | Schaefer SD Mickey BE | 1989 | Arch Otolaryngol Head Neck Surg1989,115,: | 1 |