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| 1 | 内窥镜胸交感神经链切断术治疗多汗症显示文摘目的 评价内镜下胸交感神经链切断术治疗多汗症的临床效果。 方法 回顾性分析内镜下胸交感神经链切断术治疗 5 8例多汗症的结果。 结果 5 8例均治愈 ;出现气胸 4例、代偿性多汗 2例、肋间神经痛 1例。 结论 内镜下胸交感神经链切断术比较安全。 | 胡泽勇 Churnpon Chan Prem Pillay Alvin Hong | 2001 | 中国微创外科杂志2001，1，6： | 13 |
| 2 | Why total knees fail-A modern perspective review显示文摘Historically, the most common mechanism of total kneearthroplasty(TKA) failures included aseptic loosening, instability and malalignment. As polyethylene production improved, modes of failure from polyethylene wear and subsequent osteolysis became less prevalent. Newer longitudinal studies report that infection has become the primary acute cause of failure with loosening and instability remaining as the overall greatest reasons for revision. Clinical database and worldwide national registries confirm these reports. With an increasing amount of TKA operations performed in the United States, and with focus on value-based healthcare, it is imperative to understand why total knees fail. | Zachary C Lum Alvin K Shieh Lawrence D Dorr | 2018 | World Journal of Orthopedics2018，9，4： | 9 |
| 3 | Redox therapeutics in hepatic ischemia reperfusion injury显示文摘Ischemia-reperfusion plays a major role in the injury experienced by the liver during transplantation. Much work has been done recently investigating the role of redox species in hepatic ischemia-reperfusion. As animal models are better characterized and developed, and more insights are gained into the pathophysiology of hepatic ischemia reperfusion injury in humans the questions into exactly how oxidants participate in this injury are becoming more refined. These questions include effects of cellular location, timing of injury, and ability of therapeutics to access this site are increasing our appreciation of the complexity of ischemia reperfusion and improving attempts to ameliorate its effects. In this review, we aim to discuss the various methods to alter redox chemistry during ischemia reperfusion injury and future prospects for preventing organ injury during hepatic ischemia reperfusion. | Rakesh P Patel John D Lang Alvin B Smith Jack H Crawford | 2014 | World Journal of Hepatology2014，6，1： | 9 |
| 4 | Effect of technical parameters on transjugular intrahepatic portosystemic shunts utilizing stent grafts显示文摘AIM: To assess the effect of technical parameters on outcomes of transjugular intrahepatic portosystemic shunt(TIPS) created using a stent graft.METHODS: The medical records of 68 patients who underwent TIPS placement with a stent graft from 2008 to 2014 were reviewed by two radiologists blinded to the patient outcomes.Digital Subtraction Angiographic images with a measuring catheter in two orthogonal planes was used to determine the TIPS stent-to-inferior vena cava distance(SIVCD),hepatic vein to parenchymal tract angle(HVTA),portal vein to parenchymal tract angle(PVTA),and the accessed portal vein.The length and diameter of the TIPS stent and the use of concurrent variceal embolization were recorded by review of the patient's procedure note.Data on re-intervention within 30 d of TIPS placement,recurrence of symptoms,and survival were collected through the patient's chart.Cox proportional regression analysis was performed to assess the effect of these technical parameters on primary patency of TIPS,time to recurrence of symptoms,and all-cause mortality.RESULTS: There was no significant associationbetween the SIVCD and primary patency(P = 0.23),time to recurrence of symptoms(P = 0.83),or allcause mortality(P = 0.18).The 3,6,and 12-mo primary patency rates for a SIVCD ≥ 1.5 cm were 82.4%,64.7%,and 50.3% compared to 89.3%,83.8%,and 60.6% for a SIVCD of < 1.5 cm(P = 0.29).The median time to stenosis for a SIVCD of ≥ 1.5 cm was 19.1 mo vs 15.1 mo for a SIVCD of < 1.5 cm(P = 0.48).There was no significant association between the following factors and primary patency: HVTA(P = 0.99),PVTA(P = 0.65),accessed portal vein(P = 0.35),TIPS stent diameter(P = 0.93),TIPS stent length(P = 0.48),concurrent variceal embolization(P = 0.13) and reinterventions within 30 d(P = 0.24).Furthermore,there was no correlation between these technical parameters and time to recurrence of symptoms or all-cause mortality.Recurrence of symptoms was associated with stent graft stenosis(P = 0.03).CONCLUSION: TIPS stent-to-caval distance and other parameters have no significant effect on primary patency,time to recurrence of symptoms,or all-cause mortality following TIPS with a stent-graft. | Brice Andring Sanjeeva P Kalva Patrick Sutphin Rajiv Srinivasa Alvin Anene Marc Burrell Yin Xi Anil K Pillai | 2015 | World Journal of Gastroenterology2015，21，26： | 7 |
| 5 | Clinical features and treatment outcomes of endogenous Klebsiella endophthalmitis:a 12-year review显示文摘AIM:To identify the clinical features and treatment outcomes of endogenous Klebsiella pneumoniae endophthalmitis and investigate prognostic factors of poor visual outcome.METHODS:The clinical records of all patients diagnosed with endogenous Klebsiella endophthalmitis between January 2007 to December 2018 in Prince of Wales Hospital,Hong Kong,China were retrospectively reviewed.Thorough ophthalmological examination findings were recorded in the case note,including visual acuity testing,slit-lamp examination,indirect ophthalmoscopy and B-scan ultrasonography if media opacity precluded fundus viewing.RESULTS:A total of 18 eyes in 14 patients were identified.Bilateral involvement was noted in 4 patients(28.6%).Hepatobiliary sepsis was the source in 9 patients(64.3%).Culture of intraocular fluid was positive in 5 out of 18 eyes(27.8%).Mortality was noted in 2 patients(14.3%).Mean final visual acuity was 20/1500.Six out of 16 eyes had total loss of sight(37.5%)and 3 eyes required evisceration(18.8%).Multivariate linear regression revealed poor presenting visual acuity(P=0.031)and lack of fundus view due to vitritis(P=0.02)as prognostic factors of poor visual outcome.CONCLUSION:Visual outcome of endogenous Klebsiella endophthalmitis is poor.Poor presenting visual acuity and lack of fundus view predict poor visual outcome.High index of suspicion for endophthalmitis is important in Klebsiella sepsis patients with complaints of ocular symptoms.Ophthalmological screening is recommended in noncommunicable patients with Klebsiella sepsis. | Chun Yue Mak Mary Ho Lawrence Pui-leung Iu Helena Pui-yee Sin Li Jia Chen Grace Lui Marten Erik Brelen Alvin Lerrmann Young | 2020 | International Journal of Ophthalmology(English edition)2020，13，12： | 5 |
| 6 | Epidural electrical stimulation for spinal cord injury显示文摘A long-standing goal of spinal cord injury research is to develop effective repair strategies,which can restore motor and sensory functions to near-normal levels.Recent advances in clinical management of spinal cord injury have significantly improved the prognosis,survival rate and quality of life in patients with spinal cord injury.In addition,a significant progress in basic science research has unraveled the underlying cellular and molecular events of spinal cord injury.Such efforts enabled the development of pharmacologic agents,biomaterials and stem-cell based therapy.Despite these efforts,there is still no standard care to regenerate axons or restore function of silent axons in the injured spinal cord.These challenges led to an increased focus on another therapeutic approach,namely neuromodulation.In multiple animal models of spinal cord injury,epidural electrical stimulation of the spinal cord has demonstrated a recovery of motor function.Emerging evidence regarding the efficacy of epidural electrical stimulation has further expanded the potential of epidural electrical stimulation for treating patients with spinal cord injury.However,most clinical studies were conducted on a very small number of patients with a wide range of spinal cord injury.Thus,subsequent studies are essential to evaluate the therapeutic potential of epidural electrical stimulation for spinal cord injury and to optimize stimulation parameters.Here,we discuss cellular and molecular events that continue to damage the injured spinal cord and impede neurological recovery following spinal cord injury.We also discuss and summarize the animal and human studies that evaluated epidural electrical stimulation in spinal cord injury. | Elliot H.Choi Sandra Gattas Nolan J.Brown John D.Hong Joshua N.Limbo Alvin Y.Chan Michael Y.Oh | 2021 | Neural Regeneration Research2021，16，12： | 5 |
| 7 | 组合测试故障定位的关系树模型显示文摘组合测试是一种重要的软件测试方法,该方法通常采用覆盖表作为测试用例集,适用于检测系统中由特定配置组合引发的故障.覆盖表中的一条引发系统故障的测试用例含有多个配置组合,如何确定其中哪个或哪几个配置组合引发系统故障有助于系统开发人员检测出故障原因并做出改进.目前已有一些研究尝试解决上述问题,然而这些方法都没有对待定元组关系进行深入的研究与分析,因此定位过程代价很大并且定位结果也并不完整.文中构建了一个待定元组关系树(Tuple Relationship Tree,TRT)来描述所有待定元组的关系,利用TRT可以减少生成附加测试用例的数量,并且由于TRT给出全部待定元组的清晰视图,可以避免漏掉分析可能的待定元组,特别是有重叠部分的故障元组.基于TRT,我们提出了4种选择策略来辅助故障定位.系统的实验表明:其中的路径方法可以以较高的效率得到一个比已有方法更加完整的故障定位结果. | 钮鑫涛 聂长海 CHAN Alvin | 2014 | 计算机学报2014，37，12： | 5 |
| 8 | Transfusion-transmitted hepatitis E:What we know so far?显示文摘Hepatitis E virus(HEV)is a major cause of viral hepatitis globally.There is growing concern about transfusion-transmitted HEV(TT-HEV)as an emerging global health problem.HEV can potentially result in chronic infection in immunocompromised patients,leading to a higher risk of liver cirrhosis and even death.Between 0.0013%and 0.281%of asymptomatic blood donors around the world have HEV viremia,and 0.27%to 60.5%have anti-HEV immunoglobulin G.HEV is infectious even at very low blood concentrations of the virus.Immunosuppressed patients who develop persistent hepatitis E infection should have their immunosuppressant regimen reduced;ribavirin may be considered as treatment.Pegylated interferon can be considered in those who are refractory or intolerant to ribavirin.Sofosbuvir,a nucleotide analog,showed modest antiviral activity in some clinical studies but sustained viral response was not achieved.Therefore,rescue treatment remains an unmet need.The need for HEV screening of all blood donations remains controversial.Universal screening has been adopted in some countries after consideration of risk and resource availability.Various pathogen reduction methods have also been proposed to reduce the risk of TT-HEV.Future studies are needed to define the incidence of transmission through transfusion,their clinical features,outcomes and prognosis. | Carmen Ka Man Cheung Sunny Hei Wong Alvin Wing Hin Law Man Fai Law | 2022 | World Journal of Gastroenterology2022，28，1： | 5 |
| 9 | An empirical study of DSRC V2V performance in truck platooning scenarios显示文摘 | Song Gao Alvin Lim David Bevly | 2016 | Digital Communications and Networks2016，2，4： | 5 |
| 10 | Season of the year influences infection rates following total hip arthroplasty显示文摘AIM To research the influence of season of the year on periprosthetic joint infections.METHODS We conducted a retrospective review of the entire Medicare files from 2005 to 2014. Seasons were classified as spring, summer, fall or winter. Regional variations were accounted for by dividing patients into four geographic regions as per the United States Census Bureau(Northeast, Midwest, West and South). Acute postoperative infection and deep periprosthetic infections within 90 d after surgery were tracked. RESULTS In all regions, winter had the highest incidence of periprosthetic infections(mean 0.98%, SD 0.1%) and was significantly higher than other seasons in the Midwest, South and West(P < 0.05 for all) but not the Northeast(P = 0.358). Acute postoperative infection rates were more frequent in the summer and were significantly affected by season of the year in the West.CONCLUSION Season of the year is a risk factor for periprosthetic joint infection following total hip arthroplasty(THA). Understanding the influence of season on outcomes following THA is essential when risk-stratifying patients to optimize outcomes and reduce episode of care costs. | Samuel Rosas Alvin C Ong Leonard T Buller Karim G Sabeh Tsun yee Law Martin W Roche Victor H Hernandez | 2017 | World Journal of Orthopedics2017，8，12： | 4 |
| 11 | Cytogenetic and molecular aberrations of multiple myeloma patients: a single-center study in Singapore显示文摘 | LIM Alvin Soon Tiong LIM Tse Hui SEE Karen Hsu Shien NG Yit Jun TAN Yu Min CHO0 Natasha Swee Lian LIM Sherry Xin Er YEE Yenny LAU Lai Ching TIEN Sim Leng Kumar Sathish TAN Daryl Chen Lung | 2013 | Chinese Medical Journal2013，，10： | 4 |
| 12 | Can intravesical prostatic protrusion predict bladder outlet obstruction even in men with good flow?显示文摘Objective:Men with benign prostate hyperplasia(BPH)with good urinary flow may still have bladder outlet obstruction(BOO).Intravesical prostatic protrusion(IPP)has been shown to be able to predict BOO.We aim to investigate the use of IPP to predict BOO in men with good urinary flow.Methods:One hundred and fourteen consecutive men(>50 years old)presenting with lower urinary tract symptoms suggestive of BPH were recruited in 2001 and 2002.They were evaluated with serum prostate specific antigen(PSA),uroflowmetry and transabdominal ultrasound measurement of IPP and prostate volume(PV).Pressure-flow urodynamic studies were performed on all men and BOO was defined by BOO index>40.Men with Qmax12.0 mL/s were considered to have good flow.Results:Among the 114 men,61 patients had good urinary flow.Their median age,PV and Qmax were 66 years,32.9 mm3 and 14.5 mL/s respectively.14/61(23.0%)patients had BOO and their distribution of IPP were as follows:Grade 1 e 0/20(0%)obstructed,Grade 2 e 6/22(27.3%)and Grade 3 e 8/19(42.1%).Sensitivity of Grade 2/3 IPP for BOO was 100% while specificity of Grade 3 IPP was 76.6%.The area-under-curve(AUC)for IPP was greater than that for PV(0.757 vs.0.696).Conclusion:Even in men with good flow,high grades of IPP were more likely to have BOO and hence,may be a useful adjunct to predict BOO. | Alvin Lee Han Jie Lee Kok Bin Lim Hong Hong Huang Henry Ho Keong Tatt Foo | 2016 | Asian Journal of Urology2016，3，1： | 4 |
| 13 | Inundative field releases and evaluation of three predators for Bemisia tabaci (Hemiptera: Aleyrodidae) management in three vegetable crops显示文摘sweetpotato whitefly, Bemisia tabaci (Gennadius )( 半翅类:Aleyrodidae ) ,是众多的庄稼上的一个全球害虫,包括蔬菜。一个 coccinellid 食肉动物的每周的 inundative 版本(Coccinella undecimpunctata L。[翘目:Coccinellidae ]) ,一个普通绿草蜻蛉食肉动物(Chrysoperla carnea 史蒂芬[Neuroptera:Chrysopidae ]) ,并且一个 mirid 食肉动物(Macrolophus caliginosus [瓦格纳][ 半翅类:Miridae ]) 独立地在三蔬菜庄稼被做(卷心菜[Brassica oleracea var。capitata L.] ,黄瓜[Cucumis sativus L.] ,并且挤压[Cucurbita pepo L.]) 为 sweetpotato 的管理 whitefly。约 100 万在 20 个星期期间在蔬菜庄稼被释放到每个食肉动物的 250 万个幼虫或美女。Whitefly,人口被 25%45% 在每个食肉动物被释放的每庄稼在大多数季节期间减少。每个食肉动物的效果 whitefly 开是类似的人口减小。在人口 whitefly 是低的季节(10 月) 迟了,通常,没有利益从释放食肉动物被获得。在所有庄稼在采样期间恢复的食肉动物的数字为 C 是最大的。carnea,而是这与这个食肉动物的更多的个人在实验比任何另外的食肉动物被释放的事实相应。这些结果帮助为管理 B 定义这些生来的敌人的用途。在蔬菜庄稼的 tabaci。 | Alvin M. Simmons Shaaban Abd-Rabou | 2011 | Insect Science2011，18，2： | 4 |
| 14 | Edge Computing-Based Joint Client Selection and Networking Scheme for Federated Learning in Vehicular IoT显示文摘In order to support advanced vehicular Internet-of-Things(IoT)applications,information exchanges among different vehicles are required to find efficient solutions for catering to different application requirements in complex and dynamic vehicular environments.Federated learning(FL),which is a type of distributed learning technology,has been attracting great interest in recent years as it performs knowledge exchange among different network entities without a violation of user privacy.However,client selection and networking scheme for enabling FL in dynamic vehicular environments,which determines the communication delay between FL clients and the central server that aggregates the models received from the clients,is still under-explored.In this paper,we propose an edge computing-based joint client selection and networking scheme for vehicular IoT.The proposed scheme assigns some vehicles as edge vehicles by employing a distributed approach,and uses the edge vehicles as FL clients to conduct the training of local models,which learns optimal behaviors based on the interaction with environments.The clients also work as forwarder nodes in information sharing among network entities.The client selection takes into account the vehicle velocity,vehicle distribution,and the wireless link connectivity between vehicles using a fuzzy logic algorithm,resulting in an efficient learning and networking architecture.We use computer simulations to evaluate the proposed scheme in terms of the communication overhead and the information covered in learning. | Wugedele Bao Celimuge Wu Siri Guleng Jiefang Zhang Kok-Lim Alvin Yau Yusheng Ji | 2021 | China Communications2021，18，6： | 3 |
| 15 | Venous and arterial disease in inflammatory bowel disease显示文摘 | Victoria P Tan Alvin Chung Bryan P Yan Peter R Gibson | 2013 | J Gastroenterol Hepatol2013，，7： | 3 |
| 16 | ACAR: Adaptive Connectivity Aware Routing for Vehicular Ad Hoc Networks in City Scenarios显示文摘 | Qing Yang Alvin Lim Shuang Li Jian Fang Prathima Agrawal | 2010 | Mobile Networks and Applications2010，，1： | 3 |
| 17 | Ponseti method compared with soft-tissue release for the management of clubfoot:A meta-analysis study显示文摘AIM: To compare the functional outcomes of patients who underwent open surgery vs Ponseti method for the management of idiopathic clubfoot and to determine whether correlations exist between functional outcome and radiographic measurements.METHODS: A meta-analysis of the literature was conducted for studies concerning primary treatment of patients with idiopathic clubfoot. We searched PubM ed Medline, EMBASE, and the Cochrane Library databases from January 1950 to October 2011. Meta-analyses were performed on outcomes from 12 studies. Pooled means, SDs, and sample sizes were either identified in the results or calculated based on the results of each study.RESULTS: Overall, 835 treated idiopathic clubfeet in 516 patients were reviewed. The average follow-up was 15.7 years. Patients managed with Ponseti method did have a higher rate of excellent or good outcome than patients treated with open surgery(0.76 and 0.62, respectively), but not quite to the point of statistical significance(Q = 3.73, P = 0.053). Age at surgery wasnot correlated with the functional outcome for the surgically treated patients(r =-0.32, P = 0.68). A larger anteroposterior talocalcaneal angle was correlated with a higher rate of excellent or good outcomes(r = 0.80, P = 0.006). There were no other significant correlations between the functional and radiographic outcomes.CONCLUSION: The Ponseti method should be considered the initial treatment of idiopathic clubfeet, and open surgery should be reserved for clubfeet that cannot be completely corrected. | Marios G Lykissas Alvin H Crawford Emily A Eismann Junichi Tamai | 2013 | World Journal of Orthopedics2013，4，3： | 3 |
| 18 | Regarding successful use of 23G cutter for anterior vitrectomy and scleral-fixated intraocular lens implantation显示文摘Dear Editor,I read with interest the article reporting encouraging results of anterior vitrectomy using 23G cutter during scleralfixated intraocular implantation(SFIOL)[1].I have a few observations to make.1)The authors'extrapolated values of 2.7,2.8,and 2.9 log | koushik tripathy yuan bo liang yoly fong alvin young | 2017 | International Journal of Ophthalmology(English edition)2017，10，12： | 3 |
| 19 | Scintigraphy in laryngopharyngeal and gastroesophageal reflux disease:A definitive diagnostic test?显示文摘AIM: To investigate the utility of scintigraphic studies in predicting response to laparoscopic fundoplication(LF) for chronic laryngopharyngeal reflux symptoms.METHODS: Patients with upper aero-digestive symptoms that remained undiagnosed after a period of 2 mo were studied with conventional p H and manometric studies. Patients mainly complained of cough, sore throat, dysphonia and globus. These patients were imaged after ingestion of 99m-technetium diethylene triamine pentaacetic acid. Studies were quantified with time activity curves over the pharynx, upper and lower oesophagus and background. Late studies of the lungs were obtained for aspiration. Patients underwent LF with post-operative review at 3 mo after surgery.RESULTS: Thirty four patients(20 F, 14 M) with an average age of 57 years and average duration of symptoms of 4.8 years were studied. Twenty four hour p H and manometry studies were abnormal in all patients. On scintigraphy, 27/34 patients demonstrated pharyngeal contamination and a rising or flat pharyngeal curve. Lung aspiration was evident in 50% of patients. There was evidence of pulmonary aspiration in 17 of 34 patients in the delayed study(50%). Pharyngeal contamination was found in 27 patients. All patients with aspiration showed pharyngeal contamination. In the 17 patients with aspiration, graphical time activity curve showed rising activity in the pharynx in 9 patients and a flat curve in 8 patients. In those 17 patients without pulmonary aspiration, 29%(5 patients) had either a rising or flat pharyngeal graph. A rising or flat curve predicted aspiration with a positive predictive value of 77% and a negative predictive valueof 100%. Over 90% of patients reported a satisfactory symptomatic response to LF with an acceptable sideeffect profile. CONCLUSION: Scintigraphic reflux studies offer a good screening tool for pharyngeal contamination and aspiration in patients with gastroesophageal reflux disease. | Gregory L Falk John Beattie Alvin Ing SE Falk Michael Magee Leticia Burton Hans Van der Wall | 2015 | World Journal of Gastroenterology2015，21，12： | 2 |
| 20 | Silibinin modulates TNF‐α and IFN‐γ mediated signaling to regulate COX2 and iNOS expression in tumorigenic mouse lung epithelial LM2 cells显示文摘 | Alpna Tyagi Chapla Agarwal Lori D. Dwyer‐Nield Rana P. Singh Alvin M. Malkinson Rajesh Agarwal | 2011 | Mol. Carcinog2011，，： | 2 |
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