|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 成都平原蔬菜生产中灌溉水对农药渗漏的影响研究显示文摘针对成都平原蔬菜生产中大量施用农药、大量灌水的特点,首次在国内应用欧洲官方成熟的农药评估模型——PEARL模型,研究评估了成都平原当前蔬菜生产中的灌溉方式对两种不同特性农药的渗漏的影响。杀毒矾(土壤吸附力(KOM)为0 L/kg,半衰期(DT50)为80 d)在没有灌溉条件下,其渗出土体时的最大质量浓度是190μg.L-1,而有灌溉条件下其渗出质量浓度则可达523μg.L-1,是没有灌溉条件下的2.75倍。三唑磷(KOM为200 L.kg-1,DT50为60 d)在没有灌溉条件下,其渗出土体时的最大质量浓度是0.025μg.L-1,而有灌溉条件下其渗出质量浓度为0.13μg.L-1,比没有灌溉时提高了4.2倍。不管有没有灌溉三唑磷在该地区对地下水的污染风险都很小,而杀毒矾的风险则很高。因此,农药的化学特性是影响农药渗漏的最重要的因子。在蔬菜生产中应尽量选用被土壤吸附力强、半衰期短的农药,例如:三唑磷;农药在土壤中的移动载体是土壤水,不合理的灌溉会大大地加大农药淋溶,应当多使用微喷、滴灌等节水灌溉措施,减少使用漫灌等耗水多的原始灌溉方式。 | 林超文 陈一兵 黄晶晶 Rik van den Bosch Mechteld M.S.ter Horst | 2005 | 生态环境2005，14，5： | 12 |
| 2 | Glutamate reduces experimental intestinal hyperpermeability and facilitates glutamine support of gut integrity显示文摘AIM:To assess whether glutamate plays a similar role to glutamine in preserving gut wall integrity.METHODS:The effects of glutamine and glutamate on induced hyperpermeability in intestinal cell lines were studied.Paracellular hyperpermeability was induced in Caco2.BBE and HT-29CL.19A cell lines by adding phorbol-12,13-dibutyrate(PDB) apically,after which the effects of glutamine and glutamate on horseradish peroxidase(HRP) diffusion were studied.An inhibitor of glutamate transport(L-trans-pyrrolidine-2,4-dicarboxylic acid:trans-PDC) and an irreversible blocker(acivicin) of the extracellular glutamine to glutamate converting enzyme,γ-glutamyltransferase,were used.RESULTS:Apical to basolateral HRP flux increased significantly compared to controls not exposed to PDB (n=30,P<0.001).Glutamine application reduced hyperpermeability by 19%and 39%in the respective cell lines.Glutamate application reduced hyperpermeability by 30%and 20%,respectively.Incubation of HT29CL.19A cells with acivicin and subsequent PDB and glutamine addition increased permeability levels.Incubation of Caco2.BBE cells with trans-PDC followed by PDB and glutamate addition also resulted in high permeability levels.CONCLUSION:Apical glutamate-similar to glutaminecan decrease induced paracellular hyperpermeability.Extracellular conversion of glutamine to glutamate and subsequent uptake of glutamate could be a pivotal step in the mechanism underlying the protective effect of glutamine. | Mechteld AR Vermeulen Jeffrey de Jong Mathijs J Vaessen Paul AM van Leeuwen Alexander PJ Houdijk | 2011 | World Journal of Gastroenterology2011，17，12： | 9 |
| 3 | Disappearing Colorectal Liver Metastases after Chemotherapy: Should we be Concerned?显示文摘 | Mark G. Vledder Mechteld C. Jong Timothy M. Pawlik Richard D. Schulick Luis A. Diaz Michael A. Choti | 2010 | Journal of Gastrointestinal Surgery2010，，11： | 2 |
| 4 | The impact of portal vein resection on outcomes for hilar cholangiocarcinoma显示文摘 | Mechteld C. de Jong Hugo Marques Bryan M. Clary Todd W. Bauer J. Wallis Marsh Dario Ribero Pietro Majno Ioannis Hatzaras Dustin M. Walters Andrew S. Barbas Raquel Mega Richard D. Schulick Michael A. Choti David A. Geller Eduardo Barroso Gilles Mentha Lore | 2012 | Cancer2012，，19： | 1 |
| 5 | Outcomes of extended versus limited indications for patients undergoing a liver resection for colorectal cancer liver metastases显示文摘 | Ronald M. Dam Toine M. Lodewick Maartje A.J. Broek Mechteld C. Jong Jan Willem Greve Rob L.H. Jansen Marc H.A. Bemelmans Ulf P. Neumann Steven W.M. Olde Damink Cornelis H.C. Dejong | 2014 | HPB2014，，6： | 1 |
| 6 | Clinicopathologic Analysis of Ampullary Neoplasms in 450 Patients: Implications for Surgical Strategy and Long-Term Prognosis显示文摘 | Jordan M. Winter John L. Cameron Kelly Olino Joseph M. Herman Mechteld C. Jong Ralph H. Hruban Christopher L. Wolfgang Frederic Eckhauser Barish H. Edil Michael A. Choti Richard D. Schulick Timothy M. Pawlik | 2010 | Journal of Gastrointestinal Surgery2010，，2： | 1 |
| 7 | Rates and Patterns of Recurrence Following Curative Intent Surgery for Colorectal Liver Metastasis: An International Multi-Institutional Analysis of 1669 Patients显示文摘 | Mechteld C. de Jong Carlo Pulitano Dario Ribero Jennifer Strub Gilles Mentha Richard D. Schulick Michael A. Choti Luca Aldrighetti Lorenzo Capussotti Timothy M. Pawlik | 2009 | Annals of Surgery2009，，3： | 1 |
| 8 | Clinical Prospect of Applying the Chemical Bile Duct Embolization to Achieve a Chemical Hepatectomy in the Treatment of Highly Selected Hepatolithiasis显示文摘 | Fu Yu Li Li Sheng Jiang Mechteld C. de Jong Nan Sheng Cheng Jing Qiu Cheng Ning Li Xing Wu Wu | 2009 | Surgical Laparoscopy Endoscopy & Percutaneous Techniques2009，，3： | 1 |
| 9 | Conditional Survival after Surgical Resection of Colorectal Liver Metastasis: An International Multi-Institutional Analysis of 949 Patients显示文摘 | Hari Nathan Mechteld C. de Jong Carlo Pulitano Dario Ribero Jennifer Strub Gilles Mentha Jean-Fran?ois Gigot Richard D. Schulick Michael A. Choti Luca Aldrighetti Lorenzo Capussotti Timothy M. Pawlik | 2010 | Journal of the American College of Surgeons2010，，5： | 1 |
| 10 | Surgical Management of Hepatic Neuroendocrine Tumor Metastasis: Results from an International Multi-Institutional Analysis显示文摘 | Skye C. Mayo Mechteld C. Jong Carlo Pulitano Brian M. Clary Srinevas K. Reddy T. Clark Gamblin Scott A. Celinksi David A. Kooby Charles A. Staley Jayme B. Stokes Carrie K. Chu Alessandro Ferrero Richard D. Schulick Michael A. Choti Giles Mentha Jennifer S | 2010 | Annals of Surgical Oncology2010，，12： | 1 |
| 11 | Surgical treatment of a rare complication after endoscopic stent placement for anastomotic leakage after esophageal resection显示文摘The best approach to achieve cure in esophageal cancer is a combination of chemo-radiation and surgery. However, complications occur in half of patients. The current report, reports a rare but severe complication: Complete obstruction of the esophagus, induced by preoperative chemo-radiation therapy. Normally, strictures are treated by repeated dilatations, however, in case of complete obstruction, the perforation rate of standard blind anterograde wire access and dilation is severely increased. In order to minimize the risk of perforations, the rendezvous technique was introduced. This technique involves an anterograde approach in combination with a retrograde approach in order to open and dilatate the esophagus. While technical success rates between 83% and 100% have been reported in literature, data on clinical outcomes are scarcer. The limited amount of studies available claim that success was achieved in almost half of patients. The patient in our case currently has an oral diet without restrictions and rates his quality of life with a VAS-score ten out of ten. | Marjan Klinkert Mechteld C de Jong Meindert N Sosef Annick B van Nunen Henricus J Belgers | 2017 | World Journal of Surgical Procedures2017，7，1： | 1 |
| 12 | Rates and patterns of re- currence following curative intent surgery for colorectal liver metastasis: an international multi-institutional analysis of 1669 patients 显示文摘 | Mechteld C Carlo P Dario R | 2009 | Ann Surg2009，250，3： | 1 |
| 13 | Surgery versus intra arterial therapy for neuroendocrine liver metastasis : a multicenter interna- tional analysis 显示文摘 | Skye C Mechteld C Mark B | 2011 | Ann Surg Oncol2011，，18： | 1 |
| 14 | Evidence for an impatant role of the tonoplast in the mechanism of naturally selected zinctolerance in Silene vulgaris显示文摘 | VERKLEIJ J A C KOEVOETS P L M MECHTELD M A | 1998 | Journal of Plant Physiology1998，，153： | 1 |
| 15 | Liver-directed ther- apy for hepatic metastatic in patients undergoing pancreaticoduode- nectomy: a dual-center analysis 显示文摘 | Mechteld C Michael B Guido Sclabas etal | 2010 | Ann Surg2010，，252： | 1 |
| 16 | The impact of portal vein resection on outcomes for hilar cholangiocarcinoma显示文摘 | Mechteld C. de Jong Hugo Marques Bryan M. Clary Todd W. Bauer J. Wallis Marsh Dario Ribero Pietro Majno Ioannis Hatzaras Dustin M. Walters Andrew S. Barbas Raquel Mega Richard D. Schulick Michael A. Choti David A. Geller Eduardo Barroso Gilles Mentha Lore | 2012 | Cancer2012，，19： | 1 |
| 17 | Repeat Curative Intent Liver Surgery is Safe and Effective for Recurrent Colorectal Liver Metastasis: Results from an International Multi-institutional Analysis显示文摘 | Mechteld C. Jong Skye C. Mayo Carlo Pulitano Serena Lanella Dario Ribero Jennifer Strub Catherine Hubert Jean-Fran?ois Gigot Richard D. Schulick Michael A. Choti Luca Aldrighetti Gilles Mentha Lorenzo Capussotti Timothy M. Pawlik | 2009 | Journal of Gastrointestinal Surgery2009，，12： | 1 |
| 18 | The impact of portal vein resection on outcomes for hilar cholangiocarci- noma显示文摘 | de long Mechteld C Marques Hugo Clary Bryan M | 2012 | Cancer2012，118，19： | 1 |
| 19 | Disappearing Colorectal Liver Metastases after Chemotherapy: Should we be Concerned?显示文摘 | Mark G. Vledder Mechteld C. Jong Timothy M. Pawlik Richard D. Schulick Luis A. Diaz Michael A. Choti | 2010 | Journal of Gastrointestinal Surgery2010，，11： | 1 |
| 20 | Acetylcholine: a novel regulator of airway smooth muscle remodelling? 显示文摘 | Reinoud G Johan Z Mechteld G B | 2004 | European Journal of Pharmacology2004，500，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员