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| 1 | Relationship between the exocrine and endocrine pancreas after acute pancreatitis显示文摘AIM:To determine the prevalence and time course of pancreatic exocrine insufficiency in individuals with newly diagnosed prediabetes or diabetes mellitus after acute pancreatitis.METHODS:Relevant literature cited in three major biomedical journal databases(EMBASE,MEDLINE,and Scopus)was reviewed independently by two authors.There were no language constraints but the search was limited to human studies.Studies included were cohort studies of adult patients who were discharged after an attack of acute pancreatitis.Patients were excluded if they were under 18 years of age or had a previous diagnosis of prediabetes or diabetes mellitus,pancreatic exocrine insufficiency,or chronic pancreatitis.The main outcome measure was the prevalence of concomitant pancreatic exocrine insufficiency in patients who were diagnosed with prediabetes and diabetes mellitus after an attack of acute pancreatitis.Subgroup analysis was conducted for patients who were diagnosed with prediabetes only and those who were diagnosed withdiabetes mellitus only.Subgroup analysis looking at the time course of concomitant pancreatic exocrine and endocrine insufficiency was also conducted.Pooled prevalence and corresponding 95%confidence intervals were calculated for all outcome measures and P-values<0.05 were deemed statistically significant.RESULTS:Eight clinical studies comprising of 234patients met all eligibility criteria.The pooled prevalence of newly diagnosed prediabetes or diabetes in individuals after acute pancreatitis was 43%(95%CI:30%-56%).The pooled prevalence of pancreatic exocrine insufficiency in individuals after acute pancreatitis was 29%(95%CI:19%-39%).The prevalence of concomitant pancreatic exocrine insufficiency in individuals with newly diagnosed prediabetes or diabetes was 40%(95%CI:25%-55%).The prevalence of concomitant pancreatic exocrine insufficiency among individuals with prediabetes alone and diabetes mellitus alone was 41%(95%CI:12%-75%)and 39%(95%CI:28%-51%),respectively.Further analysis showed that the prevalence of concomitant pancreatic exocrine insufficiency in individuals with prediabetes or diabetes decreases over time after an attack of acute pancreatitis.CONCLUSION:Pancreatic exocrine insufficiency occurs in 40%of individuals with newly diagnosed prediabetes or diabetes mellitus after acute pancreatitis.Further studies are needed to investigate the pathogenesis of diabetes in this setting. | Stephanie L M Das James I C Kennedy Rinki Murphy Anthony R J Phillips John A Windsor Maxim S Petrov | 2014 | World Journal of Gastroenterology2014，20，45： | 9 |
| 2 | The β-lactam antibiotic, ceftriaxone, dramatically improves survival, increases glutamate uptake and induces neurotrophins in stroke显示文摘 | Christa Th?ne-Reineke Christian Neumann Pawel Namsolleck Kristin Schmerbach Maxim Krikov Jan H Schefe Kristin Lucht Heide H?rtnagl Michael Godes Susanne Müller Kay Rumschüssel Heiko Funke-Kaiser Arno Villringer U Muscha Steckelings Thomas Unger | 2008 | Journal of Hypertension2008，，12： | 2 |
| 3 | Population, time allocation and human capital:a general equilibrium analysis for Canada 显示文摘 | Maxime F Simon H Jean M | 2009 | Economic Modelling2009，26，： | 1 |
| 4 | The Role of e-books in Reshaping the Publishing Industry显示文摘 | Maxim A M A | 2012 | Procedia-Social and Behavioral Sciences2012，62，1： | 1 |
| 5 | Population ageing and economic growth in seven OECD countries显示文摘 | Maxime Fougère Marcel Mérette | 1999 | Economic Modelling1999，，3： | 1 |
| 6 | BAI 3, CDX 2 and VIL 1: a panel of three antibodies to distinguish small cell from large cell neuroendocrine lung carcinomas显示文摘 | Muhammad F Bari Helen Brown Andrew G Nicholson Keith M Kerr John R Gosney William A Wallace Irshad Soomro Salli Muller Danielle Peat Jonathan D Moore Lesley A Ward Maxim B Freidin Eric Lim Manu Vatish David R J Snead | 2014 | Histopathology2014，，： | 1 |
| 7 | Television-viewing habits and sleep disturbance in school children显示文摘 | Owens J Maxim R McGuinn M | 1999 | Pediatrics1999，104，3： | 1 |
| 8 | Raman amplifier model in single-mode optical fiber显示文摘 | IDAN M MAXIM B | 2003 | IEEE Photon Tech Lett2003，15，12： | 1 |
| 9 | Patient-controlled sedation with propofol and remifentanil for ERCP: a randomized, controlled study显示文摘 | Maxim Mazanikov Marianne Udd Leena Kyl?np?? Outi Lindstr?m Pekka Aho Jorma Halttunen Martti F?rkkil? Reino P?yhi? | 2011 | Gastrointestinal Endoscopy2011，，2： | 1 |
| 10 | Excess neutrophil infi hration during cytomegalovirus brain infection of interleukin-lO-deficient mice 显示文摘 | Manohar B M Maxim C J Hu S | 2010 | J Neuroimmunol2010，227，12： | 1 |
| 11 | Microwave-assisted dissolution and delignification of wood in 1-ethyl-3-methylimidazolium acetate显示文摘 | WANG H MAXIM M L GURAU G | 2013 | Bioresource Technology2013，136，： | 1 |
| 12 | Development of ecoefficiency indicators for the Canadian food and beverage industry显示文摘 | Maxime D Marcotte M Arcand Y | 2006 | Journal of Cleaner Productin2006，14，67： | 1 |
| 13 | Construc- ting robust channel structures by packing metallacalix- arenes: reversible single-crystal-to-single-crystal dehy- dration显示文摘 | EEN C D MADALAN A M MAXIM C | 2009 | J Am Chem Soc2009，131，13： | 1 |
| 14 | Television-viewing habits and sleep disturbance in school children显示文摘 | Owens J Maxim R McGuinn M | 1999 | Pediatrics1999，104，3： | 1 |
| 15 | Categorization and nomenclature of vitreous silicate wools 显示文摘 | Moore M A Boymel P M Maxim L D | 2002 | Regul Toxicol Pharm2002，35，1： | 1 |
| 16 | Risk analysis for mortality from respiratory tumors in a cohort of refractory ceramic fiber workers 显示文摘 | WALKER A M MAXIM L D UTELL M | 2002 | Regul Toxicol Pharmacol2002，35，1： | 1 |
| 17 | Categorization and nomenclature of vitreous silicate wools 显示文摘 | Martin A Moore Paul M Boymel Daniel Maxim L | 2002 | Reg Toxicol Pharmacol2002，35，： | 1 |
| 18 | Hazard assessment and risk analysis of two new synthetic vitreous fibers显示文摘 | Daniel Maxim L Richard W Mast Utell M J | 1999 | Reg Toxicol Pharmacol1999，30，： | 1 |
| 19 | A phase I study of EpCAM/CD3-bispecific antibody (MT110) in patients with advanced solid tumors显示文摘 | Walter M F Martin W Maxim K | | 0，，： | 1 |
| 20 | An analysis of risks for biodiversity under the DPSIR framework显示文摘 | Maxim L Spangenberg J H OrConnor M | 2009 | Eco- logical Economics2009，69，1： | 1 |
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