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| 1 | Epigenetic changes associated with oocyte aging显示文摘It is well established that the decline in female reproductive outcomes is related to postovulatory aging of oocytes and advanced maternal age.Poor oocyte quality is correlated with compromised genetic integrity and epigenetic changes during the oocyte aging process.Here,we review the epigenetic alterations,mainly focused on DNA methylation,histone acetylation and methylation associated with postovulatory oocyte aging as well as advanced maternal age.Furthermore,we address the underlying epigenetic mechanisms that contribute to the decline in oocyte quality during oocyte aging. | SCHATTEN Heide MA JunYu SCHATTEN Heide SUN QingYuan | 2012 | Science China(Life Sciences)2012，55，8： | 16 |
| 2 | Sperm Mitochondria in Reproduction:Good or Bad and Where Do They Go?显示文摘The mitochondrion is the major energy provider to power sperm motility.In mammals,aside from the nuclear genome,mitochondrial DNA(mtDNA) also contributes to oxidative phosphorylation to impact production of ATP by coding 13 polypeptides.However,the role of sperm mitochondria in fertilization and its final fate after fertilization are still controversial.The viewpoints that sperm bearing more mtDNA will have a better fertilizing capability and that sperm mtDNA is actively eliminated during early embryogenesis are widely accepted.However,this may be not true for several mammalian species,including mice and humans.Here,we review the sperm mitochondria and their mtDNA in sperm functions,and the mechanisms of maternal mitochondrial inheritance in mammals. | Shi-Ming Luo Heide Schatten Qing-Yuan Sun | 2013 | Journal of Genetics and Genomics2013，40，11： | 8 |
| 3 | 呼肠孤病毒简介显示文摘 | Louis Vander Heide 刘文波 | 2002 | 国外畜牧科技2002，29，1： | 5 |
| 4 | Epithelial-Mesenchymal Transition in Cancer: Parallels Between Normal Development and Tumor Progression显示文摘 | Douglas S. Micalizzi Susan M. Farabaugh Heide L. Ford | 2010 | Journal of Mammary Gland Biology and Neoplasia2010，，2： | 3 |
| 5 | Skin tribology:Science friction?显示文摘The application of tribological knowledge is not just restricted to optimizing mechanical and chemical engineering problems.In fact,effective solutions to friction and wear related questions can be found in our everyday life.An important part is related to skin tribology,as the human skin is frequently one of the interacting surfaces in relative motion.People seem to solve these problems related to skin friction based upon a trial-and-error strategy and based upon on our sense for touch.The question of course rises whether or not a trained tribologist would make different choices based upon a science based strategy?In other words:Is skin friction part of the larger knowledge base that has been generated during the last decades by tribology research groups and which could be referred to as Science Friction?This paper discusses the specific nature of tribological systems that include the human skin and argues that the living nature of skin limits the use of conventional methods.Skin tribology requires in vivo,subject and anatomical location specific test methods.Current predictive friction models can only partially be applied to predict in vivo skin friction.The reason for this is found in limited understanding of the contact mechanics at the asperity level of product-skin interactions.A recently developed model gives the building blocks for enhanced understanding of friction at the micro scale.Only largely simplified power law based equations are currently available as general engineering tools.Finally,the need for friction control is illustrated by elaborating on the role of skin friction on discomfort and comfort.Surface texturing and polymer brush coatings are promising directions as they provide way and means to tailor friction in sliding contacts without the need of major changes to the product. | E.VAN DER HEIDE X.ZENG M.A.MASEN | 2013 | Friction2013，1，2： | 3 |
| 6 | Interventional treatment of the left subclavian in 2 patients with coronary steal syndrome显示文摘In patients with history of coronary artery disease angina pectoris is usually attributed to the progression of atherosclerotic lesions. However,in patients with previous coronary artery bypass graft operation(CABG) using internal mammary artery grafts,great vessel disease should also be considered. Herein we present two patients with history of CABG whose symptoms were suspicious for coronary ischemia. During cardiac catheterization reverse blood flow was observed from the left artery disease to the left internal mammary artery(LIMA) graft in both cases. After angioplasty and stent implantation of the left subclavian artery antegrade flow was restored in the LIMA grafts and both patients had complete resolution of symptoms. | Julia Heid Britta Vogel Arnt Kristen Wanda Kloos Benedikt Kohler Hugo A Katus Grigorios Korosoglou | 2017 | World Journal of Cardiology2017，9，1： | 3 |
| 7 | Big data in support of the Sustainable Development Goals:a celebration of the establishment of the International Research Center of Big Data for Sustainable Development Goals(CBAS)显示文摘In the last century the impacts of human activity on natural processes that sustain the Earth’s biosphere,atmosphere,hydrosphere and lithosphere and that provide the bed-rock of human life support systems,have grown to the extent that they pose a credible existential threat to humanity.Today,the biggest challenge for science,technology and innovation(STI)is to contribute to the pursuit of global sustainability as exemplified in the Sustainable Development Goals(SDGs)that were adopted by the United Nations(UN)in 2015. | Huadong Guo Heide Hackmann Ke Gong | 2021 | Big Earth Data2021，5，3： | 3 |
| 8 | Tendon injuries of the hand显示文摘Tendon injuries are the second most common injuries of the hand and therefore an important topic in trauma and orthopedic patients.Most injuries are open injuries to the flexor or extensor tendons,but less frequent injuries,e.g.,damage to the functional system tendon sheath and pulley or dull avulsions,also need to be considered.After clinical examination,ultrasound and magnetic resonance imaging have proved to be important diagnostic tools.Tendon injuries mostly require surgical repair,dull avulsions of the distal phalanges extensor tendon can receive conservative therapy.Injuries of the flexor tendon sheath or single pulley injuries are treated conservatively and multiple pulley injuries receive surgical repair.In the postoperative course offlexor tendon injuries,the principle of early passive movement is important to trigger an'intrinsic'tendon healing to guarantee a good outcome.Many substances were evaluated to see if they improved tendon healing;however,little evidence was found.Nevertheless,hyaluronic acid may improve intrinsic tendon healing. | Volker Schffl Andreas Heid Thomas Küpper | 2012 | World Journal of Orthopedics2012，3，6： | 3 |
| 9 | Epithelial–mesenchymal transition in development and cancer显示文摘 | Douglas S Micalizzi Heide L Ford | 2009 | Future Oncol2009，，8： | 2 |
| 10 | Big data in support of the sustainable development goals(continued):a celebration of the establishment of the International Research Center of Big Data for Sustainable Development Goals(CBAS)显示文摘The rapid development of analytics and concepts in big data enables us to diversify our efforts and enhance opportunities to implement the Sustainable Development Goals(SDGs).Big data improves the extent to which scientific evidence and innova-tive technological solutions can be adopted to meet these goals.However,the tools and methods of big data are still somewhat of a novelty in this respect. | Huadong Guo Heide Hackmann Ke Gong | 2021 | Big Earth Data2021，5，4： | 2 |
| 11 | The β-lactam antibiotic, ceftriaxone, dramatically improves survival, increases glutamate uptake and induces neurotrophins in stroke显示文摘 | Christa Th?ne-Reineke Christian Neumann Pawel Namsolleck Kristin Schmerbach Maxim Krikov Jan H Schefe Kristin Lucht Heide H?rtnagl Michael Godes Susanne Müller Kay Rumschüssel Heiko Funke-Kaiser Arno Villringer U Muscha Steckelings Thomas Unger | 2008 | Journal of Hypertension2008，，12： | 2 |
| 12 | Cloud Computing Based Optimal Driving for a Parallel Hybrid Electric Vehicle显示文摘A cloud computing based optimal driving method is proposed and its feasibility is validated through a real-world scenario simulation.Based on principles of vehicle dynamics,the driving optimization problem has been formulated into an optimal control problem constrained by traffic rules,directed at achieving lower equivalent fuel consumption and shorter travel time.In order to conveniently specify the constraints and facilitate the application of the dynamic programming(DP)algorithm,the driving optimization problem is transformed into spatial domain and discretized properly.Considering the heavy computational costs of the DP algorithm,a cloud computing based platform structure is proposed to solve the optimal driving problem in real-time.A case study is simulated based on a real-world traffic scenario in Matlab.Simulation results demonstrate that the cloud computing framework is promising toward realizing the real-time energy management for hybrid electric vehicles. | Jie Fan Yuan Zou Zehui Kong Ludger Heide | 2019 | Journal of Beijing Institute of Technology2019，28，1： | 2 |
| 13 | 含氮硼酸酯类极压抗磨剂的摩擦学性能显示文摘制备了一种含氮硼酸哺(NOB),考察了其在5CST矿物基础油中的油溶性、水解稳定性、摩擦学性能及与ZDDP的复配性能。 | 晏金灿 白雪峰 任天辉 曾祥琼 E.van der Heide | 2012 | 石油商技2012，30，5： | 2 |
| 14 | An abdominal and thyroid status with Acoustic Radiation Force Impulse Elastometry – A feasibility study显示文摘 | R.S. Goertz K. Amann R. Heide T. Bernatik M.F. Neurath D. Strobel | 2010 | European Journal of Radiology2010，，3： | 2 |
| 15 | Acoustic Radiation Force Impulse (ARFI) zur Messung der Leberelastizit?t: Eine alternative nicht invasive Methode zur Bestimmung des Leberfibrosegrades bei viraler Hepatitis显示文摘 | R. Goertz Y. Zopf V. Jugl R. Heide C. Janson D. Strobel T. Bernatik T. Haendl | 2010 | Ultraschall in Med2010，，02： | 2 |
| 16 | Real time quantitativePCR显示文摘 | Heid CA Stevens J Livak K J | | 0，，： | 2 |
| 17 | The ins and outs of FOXO shuttling:mechanisms of FOXO translocation and transcriptional regulation显示文摘 | van Der Heide LP Hoekman MF Smidt MP | 2004 | Biochem J2004，380，： | 1 |
| 18 | Relationship Governance in a Supply Chain Network显示文摘 | Jan B Heide | 2004 | Journal of Marketing2004，68，1： | 1 |
| 19 | Slow saccades and other eye movement disorders in spinocerebellar atrophy type 1显示文摘 | Klostermann W Heide W | 1997 | J Neurol1997，244，： | 1 |
| 20 | Do norms matter in marketing relationships? 显示文摘 | HEIDE JB JOHN G | 1992 | Journal of Marketing1992，56，4： | 1 |
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