|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Role of endoscopic ultrasound in the screening and follow-up of high-risk individuals for familial pancreatic cancer显示文摘Managing familial pancreatic cancer(FPC)is challenging for gastroenterologists,surgeons and oncologists.High-risk individuals(HRI)for pancreatic cancer(PC)(FPC or with germline mutations)are a heterogeneous group of subjects with a theoretical lifetime cumulative risk of PC over 5%.Screening is mainly based on annual magnetic resonance imaging(MRI)and endoscopic ultrasound(EUS).The goal of screening is to identify early-stage operable cancers or high-risk precancerous lesions(pancreatic intraepithelial neoplasia or intraductal papillary mucinous neoplasms with high-grade dysplasia).In the literature,target lesions are identified in 2%-5%of HRI who undergo screening.EUS appears to provide better identification of small solid lesions(0%-46%of HRI)and chronicpancreatitis-like parenchymal changes(14%-77%of HRI),while MRI is probably the best modality to identify small cystic lesions(13%-49%of HRI).There are no specific studies in HRI on the use of contrast-enhanced harmonic EUS.EUS can also be used to obtain tissue samples.Nevertheless,there is still limited evidence on the accuracy of imaging procedures used for screening or agreement on which patients to treat.The cost-effectiveness of screening is also unclear.Certain new EUS-related techniques,such as searching for DNA abnormalities or protein markers in pancreatic fluid,appear to be promising. | Diane Lorenzo Vinciane Rebours Frédérique Maire Maxime Palazzo Jean-Michel Gonzalez Marie-Pierre Vullierme Alain Aubert Pascal Hammel Philippe Lévy Louis de Mestier | 2019 | World Journal of Gastroenterology2019，25，34： | 2 |
| 2 | Reconstructing long time series of burned areas in arid grasslands of southern russia by satellite re- mote sensing显示文摘 | Maxim D Peter P Anna L | 2010 | Remote Sensing of Environment2010，114，8： | 1 |
| 3 | 难治性类风湿关节炎的临床特点:一项国际问卷调查研究显示文摘目的尽管按照目前欧洲抗风湿联盟(EULAR)的推荐对类风湿关节炎(rheumatoid arthritis,RA)患者进行治疗,难治性RA患者的临床症状却仍然没有得到完全控制,目前EULAR指南主要关注的是RA的早期治疗和药物治疗。本研究的目的在于分析难治性RA患者的临床特点,以及在患者管理中需要探索然而现有EULAR指南并未涉及的问题。方法对多个国家的风湿科医生进行问卷调查,分析难治性RA的临床特点。问卷包括多选题以及开放性问题,从开放性问题的回答中发现需要进一步阐明的问题以及现有EULAR指南需要增加的内容。结果410名受访者完成了调查问卷,关于难治性RA的特点:50%受访者认为基于28个关节评估的疾病活动评分(disease activity score assessing 28 joints,DAS28)>3.2或存在疾病活动的征象;42%受访者认为疲劳是其特点;48%认为至少两种传统合成改变病情抗风湿药(DMARDs)以及使用至少两种生物制剂或靶向合成DMARDs治疗失败;89%认为糖皮质激素不能减量到5 mg/天或泼尼松不能减量到10 mg/天或同等剂量的其他激素。另外,现有EULAR指南中应增加合并症和关节外表现的干预以及多种药物联合治疗等重要内容。结论目前风湿科医生对难治性RA的定义有很大争议。难治性RA患者的很多重要问题目前EULAR指南中均没有涉及。 | Nadia MT Roodenrijs Maria J H de Hair Marlies C van der Goes Johannes WG Jacobs Paco MJ Welsing Désirée van der Heijde Daniel Aletaha Maxime Dougados Kimme L Hyrich Iain B McInnes Ulf Mueller-Ladner Ladislav Senolt Zoltan Szekanecz Jacob Mvan Laar Nagy Gyorgy 黄艳荣(译) 张卓莉(审校) | 2019 | 英国医学杂志中文版2019，22，2： | 1 |
| 4 | Catalytic combustion of methane over palladium-based catalysts 显示文摘 | Ciuparu D Maxim R L Altman E | 2002 | Catalysis Review2002，44，： | 1 |
| 5 | Single-sided magnetic resonance profiling in biological and materials science显示文摘 | Maxime L Emesto D Juan P Blumich B | 2012 | J Magn Reson2012，215，： | 1 |
| 6 | Diffusion dynamics of glycine receptors revealed by single-quantum dot tracking 显示文摘 | Maxime D H Camilla L C Philippe R | 2003 | Science2003，302，： | 1 |
| 7 | Workplace monitoring of occupational exposure to refractory ceramic fiber-a 17-year , retrospective显示文摘 | MAXIM L D ALLSHOUSE J FAIRFAX R E | 2008 | Inhal Toxicol2008，20，3： | 1 |
| 8 | Categorization and nomenclature of vitreous silicate wools 显示文摘 | Moore M A Boymel P M Maxim L D | 2002 | Regul Toxicol Pharm2002，35，1： | 1 |
| 9 | Risk analysis for mortality from respiratory tumors in a cohort of refractory ceramic fiber workers 显示文摘 | WALKER A M MAXIM L D UTELL M | 2002 | Regul Toxicol Pharmacol2002，35，1： | 1 |
| 10 | Diameter- and length-dependent self-organizations of multi-walled carbon nanotubes on spherical alu-mina microparticles显示文摘 | He D L Michael B Maxime G | 2010 | Carbon2010，48，4： | 1 |
| 11 | Risk analysis for mortality from respiratory tumors in a cohort of refractory ceramic fiber workers显示文摘 | Walker A M Maxim L D Utell M | 2002 | Regul Toxicol Pharmacol2002，35，1： | 1 |
| 12 | Hazard Assessment and Risk Analysis of Two New Synthetic Vitreous Fibers显示文摘 | Maxim L D Mast R W | 1999 | Regulatory Toxicology and Pharma- cology1999，，30： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员