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| 1 | Biochar compost blends facilitate switchgrass growth in mine soils by reducing Cd and Zn bioavailability显示文摘Biochars have the potential to reclaim mine-impacted soils;however,their variable physico-chemical properties incite specu-lation about their successful remediation performance.This investigation examined the capability of biochars produced from three different feedstocks along with a compost blend to improve switchgrass growth conditions in a mine-impacted soil by examining influences on soil pH,grass metal contents,and soil-extractable metal concentrations.Cadmium(Cd)-and zinc(Zn)-contaminated mine soil was collected from a site near Webb City,Missouri,USA-a location within the Tri-State Min-ing District.In a full factorial design,soil was treated with a 0%,2.5%,and 5%(w/w)compost mixture(wood chips+beef cattle manure),and 0%,2.5%and 5%of each biochar pyrolyzed from beef cattle manure,poultry litter,and lodgepole pine feedstocks.Switchgrass(Panicum virgatum,‘Cave-In-Rock’variety)was grown in a greenhouse for 50 days and the mass of shoots(above-ground biomass)and roots was assessed,while soil pH,deionized H_(2)O-and 0.01 M CaCl_(2)-extractable Cd and Zn concentrations were measured.Poultry litter biochar and compost had the greatest ability to raise soil pH(from 4.40 to 6.61),beef cattle manure biochar and compost moderately raised pH(from 4.4 to 5.92),and lodgepole pine biochar and compost weakly raised pH(from 4.40 to 5.05).Soils treated with beef cattle manure biochar,poultry litter biochar signifi-cantly reduced deionized H_(2)O-and 0.01 M CaCl_(2)-extractable Cd and Zn concentrations,while lodgepole pine biochar-treated soils showed mixed results.Switchgrass shoot and root masses were greatest in soil treated with compost in combination with either beef cattle manure biochar or poultry litter biochar.Soils treated with 5%beef cattle manure biochar+5%compost had greater reductions in total Cd and Zn concentrations measured in switchgrass shoots and roots compared to the other two treatments.The three biochars and compost mixtures applied to heavy metal,mine-impacted soil had considerable performance dissimilarities for improving switchgrass productivity.Switchgrass growth was noticeably improved after treatment with the compost in combination with biochar from beef cattle manure or poultry litter.This may be explained by the increased soil pH that promoted Zn and Cd precipitation and organic functional groups that reduced soil-available heavy metal concentrations.Our results imply that creating designer biochars is an important management component in developing successful mine-site phytostabilization programs. | Jeffrey M.Novak James A.Ippolito Donald W.Watts Gilbert C.Sigua Thomas F.Ducey Mark G.Johnson | 2019 | Biochar2019，1，1： | 8 |
| 2 | Morbidity and Mortality Analysis of 200 Treatments With Cytoreductive Surgery and Hyperthermic Intraoperative Intraperitoneal Chemotherapy Using the Coliseum Technique显示文摘 | Arvil D. Stephens MD Robert Alderman PA-C David Chang MD Gary D. Edwards PA-C Jesus Esquivel MD Gilbert Sebbag MD Mark A. Steves MD Paul H. Sugarbaker MD | 1999 | Annals of Surgical Oncology1999，，8： | 5 |
| 3 | 嵌合抗原受体T细胞产品最新研发进展显示文摘作为近年来发展最快的免疫治疗手段之一,嵌合抗原受体T(chimeric antigen receptors-T,CAR-T)细胞疗法在血液肿瘤治疗中表现出了良好的疗效和可控的安全性能,但在实体瘤治疗方面还面临着诸多挑战。本文综述了CAR-T细胞疗法上市产品的临床表现及其生命周期管理进展,探讨了热门靶点如CD19,BCMA,HER2和GPC3的最新研发进展和挑战,并从增强CAR-T细胞治疗产品的疗效和持续性及提高产品安全性等角度,探讨了面临的问题和解决方案。 | 刘千勇 Mark GILBERT 李怡平 | 2021 | 中国新药杂志2021，30，19： | 4 |
| 4 | Full-scale partial nitritation/anammox experiences – An application survey显示文摘 | Susanne Lackner Eva M. Gilbert Siegfried E. Vlaeminck Adriano Joss Harald Horn Mark C.M. van Loosdrecht | 2014 | Water Research2014，，： | 3 |
| 5 | Differing profiles of people diagnosed with acute and chronic hepatitis B virus infection in British Columbia,Canada显示文摘AIM To describe the characteristics of people diagnosed with acute and chronic hepatitis B virus(HBV) infection in British Columbia(BC).METHODS We used data from the BC Hepatitis Testers Cohort(BCHTC),which includes all individuals tested for hepatitis C virus(HCV) or human immunodeficiency virus(HIV) or those diagnosed with HBV or active tuberculosis in BC since 1990.These data were integrated with prescription drug,medical visit,hospitalization and mortality data.HBV cases were classified as acute or chronic according to provincial guidelines.We compared characteristics of individuals by HBV infection group(acute,chronic and negative).Factors associated with acute or chronic HBV infection were assessed with multinomial logistic regression models in comparison to the HBV negative group.RESULTS46498 of the 1058056 eligible BC-HTC participants were diagnosed with HBV infection.4.3% of HBV positive individuals were diagnosed with acute HBV infections while 95.7% had chronic infections.Problematic alcohol use,injection drug use,and HIV or HCV co-infection were more common among individuals diagnosed with acute HBV compared to those with chronic infections and HBV negative individuals.In multivariable multinomial logistic regression models,we observed significant associations between acute or chronic HBV diagnosis and being male,age at HBV diagnosis or birth cohort,South and East Asian ethnicity,HCV or HIV infection,and injection drug use.The odds of acute HBV decreased with increasing age among people who inject drugs,while the opposite was true for chronic HBV.Persons with acute HBV were predominantly White(78%) while those with chronic HBV were mostly East Asian(60%).Relative to Whites,East Asians had 12 times greater odds of being diagnosed with chronic HBV infection.These odds increased with increasing socioeconomic deprivation.CONCLUSION Differences in the profiles of people diagnosed with acute and chronic HBV infection necessitate differentiated screening,prevention,care and treatment programs. | Mawuena Binka Zahid A Butt Stanley Wong Mei Chong Jane A Buxton Nuria Chapinal Amanda Yu Maria Alvarez Maryam Darvishian Jason Wong Gina McGowan Mikhail Torban Mark Gilbert Mark Tyndall Mel Krajden Naveed Z Janjua | 2018 | World Journal of Gastroenterology2018，24，11： | 3 |
| 6 | Genetic Interaction of PGE2 and Wnt Signaling Regulates Developmental Specification of Stem Cells and Regeneration显示文摘 | Wolfram Goessling Trista E. North Sabine Loewer Allegra M. Lord Sang Lee Cristi L. Stoick-Cooper Gilbert Weidinger Mark Puder George Q. Daley Randall T. Moon Leonard I. Zon | 2009 | Cell2009，，6： | 2 |
| 7 | An exploratory examination of urban Tourisom Impact, With Reference to Residents Attitudes, in the Cities of Canterbury and Guidford 显示文摘 | David Gilbert Mark Clark | 1997 | Cities1997，14，6： | 1 |
| 8 | Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease显示文摘 | Gilbert S Omenn Gary E Goodman Mark D Thomquist | 1996 | The New England Journal of Medicine1996，334，： | 1 |
| 9 | An exploratory examination of urban tourism impact, with reference to residents attitudes, in the cities of Canterbury and Guidford 显示文摘 | DAVID GILBERT MARK CLARK | 1997 | Cities1997，14，6： | 1 |
| 10 | Time-dependent and thermal behaviour of spherical shallow concrete domes显示文摘 | Ehab Hamed Mark A. Bradford R. Ian Gilbert | 2009 | Engineering Structures2009，，9： | 1 |
| 11 | Recurrence of tuberculosis in a low-incidence setting显示文摘 | Dobler CC Crawford A Jelfs P Gilbert G Marks G | 2009 | Eur Respir J2009，33，1： | 1 |
| 12 | Pathogenesis of Acute Kidney Injury: Foundation for Clinical Practice显示文摘 | Gilbert R. Kinsey Mark D. Okusa | 2011 | American Journal of Kidney Diseases2011，，2： | 1 |
| 13 | Clinical applications of electrochemotherapy显示文摘 | Richard Heller Richard Gilbert Mark j jaroszeski | 1999 | Advanced Drug Delivery Reviews1999，，35： | 1 |
| 14 | Microbial response to designer biochar and compost treatments for mining impacted soils显示文摘The Oronogo-Duenweg mining belt is a designated United States Environmental Protection Agency Superfund site due to lead-contaminated soil and groundwater by former mining and smelting operations.Sites that have undergone remediation-in which the O,A,and B horizons have been removed alongside the lead contamination-have an exposed C horizon and are incalcitrant to revegetation efforts.Soils also continue to contain quantifiable Cd and Zn concentrations.To improve soil conditions and encourage successful site revegetation,our study employed three biochars,sourced from different feedstocks(poultry litter,beef cattle manure,and lodgepole pine),at two rates of application(2.5%,and 5%),coupled with compost(0%,2.5%and 5%application rates).Two plant species-switchgrass(Panicum virgatum)and buffalograss(Bouteloua dactyloides)-were grown in the amended soils.Amendment of soils with poultry litter biochar applied at 5%resulted in the greatest reduction of soil bioavailable Cd and Zn.Above-ground biomass yields were greatest with beef cattle manure biochar applied at 2.5%with 5%compost,or with 5%biochar at 2.5%and 5%compost rates.Maximal microbial biomass was achieved with 5%poultry litter biochar and 5%compost,and microbial communities in soils amended with poultry litter biochar distinctly clustered away from all other soil treatments.Additionally,poultry litter biochar amended soils had the highest enzyme activity rates forβ-glucosidase,N-acetyl-β-D-glucosaminidase,and esterase.These results suggest that soil reclamation using biochar and compost can improve mine-impacted soil biogeophysical characteristics,and potentially improve future remediation efforts. | Thomas F.Ducey Jeffrey M.Novak Gilbert C.Sigua James A.Ippolito Hannah C.Rushmiller Donald W.Watts Kristin M.Trippe Kurt A.Spokas Kenneth C.Stone Mark G.Johnson | 2021 | Biochar2021，3，3： | 1 |
| 15 | Clinical apphcations of electrochemotherapy 显示文摘 | Richard Heller Richard Gilbert Mark J | 1999 | Advanced Drug Delivery Reviews1999，，35： | 1 |
| 16 | Psychosocial well-being and quality of life among women newly diagnosed with genital herpes显示文摘 | Mark H Gilbert L Nanda J | | 0，，03： | 1 |
| 17 | Malignant neoplasms subsequent to treatment of inflammatory bowel disease with 6-mercaptopurine显示文摘 | Burton I Korelitz Felice J Mirsky Mark R Fleisher Jonathan I Warman Nathaniel Wisch Gilbert W Gleim | 1999 | The American Journal of Gastroenterology1999，，11： | 1 |
| 18 | Assessment of Leader Problem-solving Capabilities显示文摘 | Zaccaro Stephen J Mumford Michael D Connelly Mary Shane Marks Michelle A Gilbert Janelle A | 2000 | Leadership Quarterly2000，，11： | 1 |
| 19 | The role of chemotherapy in the treatment of patients with brain metastases from solid tumors显示文摘 | Tobias Walbert Mark R. Gilbert | 2009 | International Journal of Clinical Oncology2009，，4： | 1 |
| 20 | Chitosan: potential use as a bioactive coating for orthopaedic and craniofacial/dental implants显示文摘 | Joel D. Bumgardner Robin Wiser Patrick D. Gerard Patrick Bergin Betsy Chestnutt Mark Marini Victoria Ramsey Steve H. Elder Jerome A. Gilbert | 2003 | Journal of Biomaterials Science Polymer Edition2003，，5： | 1 |
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