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| 1 | Intraductal ultrasound substantiates diagnostics of bile duct strictures of uncertain etiology显示文摘AIM:To report the largest patient cohort study investigating the diagnostic yield of intraductal ultrasound (IDUS) in indeterminate strictures of the common bile duct.METHODS:A patient cohort with bile duct strictures of unknown etiology was examined by IDUS.Sensitivity,specificity and accuracy rates of IDUS were calculated relating to the definite diagnoses proved by histopathology or long-term follow-up in those patients who did not undergo surgery.Analysis of the endosonographic report allowed drawing conclusions with respect to the T and N staging in 147 patients.IDUS staging was compared to the postoperative histopathological staging data allowing calculation of sensitivity,specificity and accuracy rates for T and N stages.The endoscopic retrograde cholangio-pancreatography and IDUS procedures were performed under fluoroscopic guidance using a side-viewing duodenoscope (Olympus TJF 160,Olympus,Ltd.,Tokyo,Japan).All procedures were performed under conscious sedation (propofol combined with pethidine) according to the German guidelines.For IDUS,a 6 F or 8 F ultrasound miniprobe was employed with a radial scanner of 15-20 MHz at the tip of the probe (Aloka Co.,Tokyo,Japan).RESULTS:A total of 397 patients (210 males,187 females,mean age 61.43 ± 13 years) with indeterminate bile duct strictures were included.Two hundred and sixty-four patients were referred to the department of surgery for operative exploration,thus surgical histopathological correlation was available for those patients.Out of 264 patients,174 had malignant disease proven by surgery,in 90 patients benign disease was found.In these patients decision for surgical exploration was made due to suspicion for malignant disease in multimodal diagnostics (computed tomography scan,endoscopic ultrasound or magnetic resonance imaging).Twenty benign bile duct strictures were misclassified by IDUS as malignant while 14 patients with malignant strictures were initially misdiagnosed by IDUS as benign resulting in sensitivity,specificity and accuracy ratesof 93.2%,89.5% and 91.4%,respectively.In the subgroup analysis of malignancy prediction,IDUS showed best performance in cholangiocellular carcinoma as underlying disease (sensitivity rate,97.6%) followed by pancreatic carcinoma (93.8%),gallbladder cancer (88.9%) and ampullary cancer (80.8%).A total of 133 patients were not surgically explored.32 patients had palliative therapy due to extended tumor disease in IDUS and other imaging modalities.Ninety-five patients had benign diagnosis by IDUS,forceps biopsy and radiographic imaging and were followed by a surveillance protocol with a follow-up of at least 12 mo;the mean follow-up was 39.7 mo.Tumor localization within the common bile duct did not have a significant influence on prediction of malignancy by IDUS.The accuracy rate for discriminating early T stage tumors (T1) was 84% while for T2 and T3 malignancies the accuracy rates were 73% and 71%,respectively.Relating to N0 and N1 staging,IDUS procedure achieved accuracy rates of 69% for N0 and N1,respectively.Limitations:Pretest likelihood of 52% may not rule out bias and overinterpretation due to the clinical scenario or other prior performed imaging tests.CONCLUSION:IDUS shows good results for accurate diagnostics of bile duct strictures of uncertain etiology thus allowing for adequate further clinical management. | Tobias Meister Hauke S Heinzow Carina Woestmeyer Philipp Lenz Josef Menzel Torsten Kucharzik Wolfram Domschke Dirk Domagk | 2013 | World Journal of Gastroenterology2013，19，6： | 19 |
| 2 | Clinical outcome and predictors of survival after TIPS insertion in patients with liver cirrhosis显示文摘AIM:To determine the clinical outcome and predictors of survival after transjugular intrahepatic portosystemic stent shunt (TIPS) implantation in cirrhotic patients. METHODS:Eighty-one patients with liver cirrhosis and consequential portal hypertension had TIPS implantation (bare metal) for either refractory ascites (RA) (n= 27) or variceal bleeding (VB) (n = 54). Endpoints for the study were:technical success, stent occlusion and stent stenosis, rebleeding, RA and mortality. Clinical records of patients were collected and analysed. Baseline characteristics [e.g., age, sex, CHILD score and the model for end-stage liver disease score (MELD score), underlying disease] were retrieved. The Kaplan-Meier method was employed to calculate survival from the time of TIPS implantation and comparisons were made by log rank test. A multivariate analysis of factors influencing survival was carried out using the Cox proportional hazards regression model. Results were expressed as medians and ranges. Comparisons between groups were performed by using the Mann-Whitney Utest and the χ 2 test as appropriate. RESULTS:No difference could be seen in terms of age, sex, underlying disease or degree of portal pressure gradient (PPG) reduction between the ascites and the bleeding group. The PPG significantly decreased from 23.4 ± 5.3 mmHg (VB) vs 22.1 ± 5.5 mmHg (RA) before TIPS to 11.8 ± 4.0 vs 11.7 ± 4.2 after TIPS implantation (P = 0.001 within each group). There was a tendency towards more patients with stage CHILD A in the bleeding group compared to the ascites group (24 vs 6, P = 0.052). The median survival for the ascites group was 29 mo compared to > 60 mo for the bleeding group (P = 0.009). The number of radiological controls for stent patency was 6.3 for bleeders and 3.8 for ascites patients (P = 0.029). Kaplan-Meier calculation indicated that stent occlusion at first control (P = 0.027), ascites prior to TIPS implantation (P = 0.009), CHILD stage (P = 0.013), MELD score (P = 0.001) and those patients not having undergone liver transplantation (P = 0.024) were significant predictors of survival. In the Cox regression model, stent occlusion (P = 0.022), RA (P = 0.043), CHILD stage (P = 0.015) and MELD score (P = 0.004) turned out to be independent prognostic factors of survival. The anticoagulation management (P = 0.097), the porto-systemic pressure gradient (P= 0.460) and rebleeding episodes (P = 0.765) had no significant effect on the overall survival. CONCLUSION:RA, stent occlusion, initial CHILD stage and MELD score are independent predictors of survival in patients with TIPS, speaking for a close follow-up in these circumstances. | Hauke S Heinzow Philipp Lenz Michael Khler Frank Reinecke Hansjrg Ullerich Wolfram Domschke Dirk Domagk Tobias Meister | 2012 | World Journal of Gastroenterology2012，18，37： | 17 |
| 3 | 以α-硅烷封端聚醚为聚合物的湿固化弹性粘合剂显示文摘选择合适的α-硅烷与聚醚反应,制得硅烷封端的聚醚(STP-E)。探讨了以α-硅烷封端聚醚制备的湿固化弹性粘合剂的特点,以及填充剂、增塑剂和白炭黑对粘合剂性能的影响。 | 王洪宇 Wolfram Dr.Schindler 韩颖娟 魏婕 | 2010 | 中国建筑防水2010，，18： | 17 |
| 4 | Deep-learning based denoising and reconstruction of super-resolution structured illumination microscopy images显示文摘Super-resolution structured illumination microscopy(SR-SIM) provides an up to twofold enhanced spatial resolution of fluorescently labeled samples. The reconstruction of high-quality SR-SIM images critically depends on patterned illumination with high modulation contrast. Noisy raw image data(e.g., as a result of low excitation power or low exposure time), result in reconstruction artifacts. Here, we demonstrate deep-learning based SR-SIM image denoising that results in high-quality reconstructed images. A residual encoding–decoding convolutional neural network(RED-Net) was used to successfully denoise computationally reconstructed noisy SR-SIM images.We also demonstrate the end-to-end deep-learning based denoising and reconstruction of raw SIM images into high-resolution SR-SIM images. Both image reconstruction methods prove to be very robust against image reconstruction artifacts and generalize very well across various noise levels. The combination of computational image reconstruction and subsequent denoising via RED-Net shows very robust performance during inference after training even if the microscope settings change. | ZAFRAN HUSSAIN SHAH MARCEL MÜLLER TUNG-CHENG WANG PHILIP MAURICE SCHEIDIG AXEL SCHNEIDER MARK SCHÜTTPELZ THOMAS HUSER WOLFRAM SCHENCK | 2021 | Photonics Research2021，9，5： | 11 |
| 5 | Surgical strategies in the therapy of non-small cell lung cancer显示文摘Lung cancer represents the leading cause of cancer mortality worldwide. Despite improvements in preoperative staging, surgical techniques, neoadjuvant/adjuvant options and postoperative care, there are still major difficulties in significantly improving survival, especially in locally advanced non-small cell lung cancer(NSCLC). To date, surgical resection is the primary mode of treatment for stage?Ⅰ?and Ⅱ NSCLC and has become an important component of the multimodality therapy of even more advanced disease with a curative intention. In fact, in NSCLC patients with solitary distant metastases, surgical interventions have been discussed in the last years. Accordingly, this review displays the recent surgical strategies implemented in the therapy of NSCLC patients. | Feras Al-Shahrabani Daniel Vallbhmer Sebastian Angenendt Wolfram T Knoefel | 2014 | World Journal of Clinical Oncology2014，5，4： | 10 |
| 6 | Metastasized pancreatic carcinoma with neoadjuvant FOLFIRINOX therapy and R0 resection显示文摘Patients with metastasized carcinoma of the pancreas have a very poor prognosis, and long-term survival cannot be expected. This case report describes two patients with an initial diagnosis of metastatic pancreatic cancer, both with hepatic metastases and one with an additional peritoneal carcinomatosis. Initially, both patients were treated intravenously with the FOLFIRINOX chemotherapy regimen, consisting of 5-FU, folinic acid, irinotecan and oxaliplatin. Surprisingly, the FOLFIRINOX treatment resulted in complete resolution of the hepatic metastases in both patients, with no lesions detectable by computed tomography scan. Furthermore, treatment response included decreased diameter of the primary tumor in the tail of the pancreas and disappearance of the additional peritoneal carcinomatosis. Both patients were discussed by our multidisciplinary tumor board, which recommended surgical resections of the carcinoma. The R0 resection of the primary tumor was successful in both cases and, interestingly, the resected tissues showed no evidence of the hepatic metastases intraoperatively. In the first case, the patient received a postoperative 6-mo course of adjuvant chemotherapy with gemcitabine. In the second case, the patient continued to receive the FOLFIRINOX regimen for an additional 6 mo postoperatively. At 12 mo after the operation, a nonresectable retroperitoneal lymph node metastasis was detected in the first patient, whereas the second patient remained in complete remission at the time of this report(5 mo after the adjuvant therapy was discontinued). This case report is the first of its kind to describe two cases of hepatic metastatic pancreatic carcinoma that were resectable following treatment with FOLFIRINOX. Further studies are required to examine the role of FOLFIRINOX as a neoadjuvant treatment option in subgroups of patients with initially metastasized pancreatic carcinoma. | Sophie Schneitler Patric Krpil Jasmin Riemer Gerald Antoch Wolfram Trudo Knoefel Dieter Hussinger Dirk Graf | 2015 | World Journal of Gastroenterology2015，21，20： | 9 |
| 7 | Intrahepatic endometriosis as differential diagnosis: Case report and literature review显示文摘Intrahepatic endometriosis is one of the rarest forms of atypical endometriosis; only eighteen cases have been reported in the English literature. We describe the case of a 32-year-old woman, who presented with persistent, non-cyclical upper right quadrant abdominal pain, a central liver cyst, and no history of endometriosis. Three years previous, she was diagnosed with an intrahepatic cyst. The lesion progressed and two laparoscopic deroofing-operations were performed, yet the diagnosis of intrahepatic endometriosis was never reached. She presented in our clinic with further progress of the cyst as well as obstruction of the intrahepatic biliary system. The magnetic resonance imaging showed a 9.5 cm × 12 cm, lobulated intrahepatic cyst. We performed an ultrasonic pericystectomy. Immunostaining confirmed intrahepatic endometriosis. Only one of the previously described eighteen patients with intrahepatic endometriosis presented with cyclical pain in the upper right abdominal quadrant accompanying menstruation. This lack of a 'typical' clinic makes it challenging to diagnose extragonadal endometriosis without histopathology. A previous history of endometriosis was described in only twelve cases, thus the diagnosis of this condition should not be limited to patients with a known history of endometriosis. Six of 18 patients were postmenopausal, demonstrating this condition is not limited to women of reproductive age. A preoperative diagnosis was only reached in seven of the previously described cases, highlighting the importance of preoperative biopsies. Yet due to the potential adverse effects, a transhepatic biopsy must be discussed individually. Although rare, intrahepatic endometriosis should always be considered as a differential diagnosis in women with recurrent hepatic cysts, regardless of age or previous medical history. In such cases, histology is essential and a pericystectomy should be performed as standard of care. | Georg Fluegen Frank Jankowiak Luisa Zacarias Foehrding Feride Kroepil Wolfram T Knoefel Stefan A Topp | 2013 | World Journal of Gastroenterology2013，19，29： | 9 |
| 8 | Osteoclast-like giant cell tumors of the pancreas and liver显示文摘Osteoclast-like giant cell tumors (OGCT) are rare abdominal tumors, which mainly occur in the pancreas. The neoplasms are composed of two distinct cell populations and frequently show an inhomogenous appearance with cystic structures. However, due to the rarity of these tumors, only very limited clinical data are available. Imaging features and sonographic appearance have hardly been characterized. Here we report on two cases of osteoclast-like giant cell tumors, one located within the pancreas, the other within the liver, in which OGCTs are extremely rare. Both patients were investigated by contrast sonography, which demonstrated a complex, partly cystic and strongly vascularized tumor within the head of the pancreas in the first patient and a large, hypervascularized neoplasm with calcifications within the liver in the second patient. The liver OGCT responded well to a combination of carboplatin, etoposide and paclitaxel. With a combination of surgical resection, radiofrequency ablation and chemotherapy, the patient’s survival is currently more than 15 mo, making him the longest survivor with an OGCT of the liver to date. | Juergen Bauditz Birgit Rudolph Wolfram Wermke | 2006 | World Journal of Gastroenterology2006，12，48： | 9 |
| 9 | 消化系神经内分泌肿瘤超声造影表现特征分析显示文摘目的分析消化系统神经内分泌瘤(NET)原发病灶及肝转移灶超声造影(CEUS)表现特征,评价CEUS诊断消化系NET的价值。方法 2005—2009年Charité医院收治90例经手术和(或)穿刺活检病理确诊的消化系NET患者。回顾性分析79个消化系NET原发病灶、510个肝转移灶常规超声表现及69个原发病灶、70个肝转移灶CEUS表现。结果常规超声示79个消化系NET原发病灶以低回声和混合回声为主,69.7%(23/33)的小肠NET原发病灶和64.3%(18/28)的胰腺NET原发病灶内部回声不均,27.8%(22/79)的消化系NET原发病灶含部分液化区。CEUS示69个消化系NET原发病灶中93.3%(63/69)血供丰富,72.5%(50/69)呈向心性增强。常规超声示510个肝转移灶中39.1%(199/510)表现为低回声,34.1%(174/510)为高回声,23.7%(121/510)为混合回声;32.7%(167/510)的肝转移灶周围存在声晕。CEUS示肝转移灶中70.0%(49/70)为向心性增强,27.1%(19/70)为快速整体增强,呈离心充盈的仅占2.9%(2/70);78.7%(55/70)的肝转移灶在60s内开始出现增强消退。结论消化系NET原发病灶及肝转移灶具有特征性CEUS表现。CEUS可作为NET影像诊断学方法之一。 | 徐晓蓉 Wolfram Wermke 徐辉雄 | 2012 | 中华医学超声杂志(电子版)2012，9，10： | 9 |
| 10 | Differential effects on apoptosis induction in hepatocyte lines by stable expression of hepatitis B virus X protein显示文摘瞄准:肝炎 B 蛋白质 X (HBx ) 被显示了是弱 oncogenic 在试管内。HBx 的转变活动与肿瘤的功能压制的几的抑制或 p53 被连接了。我们学习了 HBx 是否可以在取决于房间类型的 p53 上有不同效果。方法:我们使用了人的肝细胞瘤房间线 HepG2 和使不朽的鼠科的 hepatocyte 线 AML12 并且稳定地分析了表示了 HBx 的生理的数量的 transfected 克隆。P53 被紫外照耀导致。结果:由紫外照耀的 p53 正式就职由 HBx 的稳定的表示是未受影响的。然而,变得被 p53 激活的 cyclin 激酶禁止者 p21 (waf/cip/sdi ) 的表示在 HBx 被影响转变房间线 AML12-HBx9,然而并非在 HepG2。在 AML-HBx9,房间, p21 (waf/cip/sdi ) 蛋白质表示和 p21 (waf/cip/sdi ) 抄写是 deregulated。而且, apoptosis 的过程在调查的二根房间线以相反的方法被影响。当 HBx 的稳定的表示提高了紫外照耀在 HepG2 房间导致的 apoptosis 时, apoptosis 在 HBx 被减少转变 AML12-HBx9。P53 镇压了从 HBV enhancer 的抄写我,当由紫外照耀从表示向量或在内长的 p53 的正式就职以后表示了时。由内长的 p53 的压抑由在两根房间线的稳定地表示的 HBx 部分是可逆的。结论:HBx 的稳定的表示导致取决于使用的房间线的紫外照耀导致的 apoptosis 的解除管制。而在癌的表示导出 hepatocyte 线 HBx,在一根使不朽的 hepatocyte 线, HBx 扮演了 anti-apoptotic 提高的 apoptosis。 | Nicola Fiedler Ellen Quant Ludger Fink Jianguang Sun Ralph Schuster Wolfram H Gerlich Stephan Schaefer | 2006 | World Journal of Gastroenterology2006，12，29： | 8 |
| 11 | Sporadic versus hereditary gastrinomas of the duodenum and pancreas: Distinct clinico-pathological and epidemiological features显示文摘Gastrinomas are defined as gastrin secreting tumors that are associated with Zollinger-Ellison syndrome (ZES). ZES is characterized by elevated fasting gastrin serum levels, positive secretin stimulation test and clinical symptoms such as recurrent peptic ulcer disease, gastroesophageal re?ux disease and occasional diarrhea. Genetically, nonhereditary (sporadic) gastrinomas are distinguished from hereditary gastrinomas, which are associated with multiple endocrine neoplasia type 1 (MEN1) syndrome. In general, duodenal gastrinomas are small and solitary if they are sporadic and multiple as well as hereditary. The sporadic gastrinomas occur in the duodenum or in the pancreas while the hereditary gastrinomas almost all occur in the duodenum. Our series of 77 sporadic duodenal neuroendocrine tumors (NETs) includes 18 patients (23.4%) with gastrinomas and ZES. Of 535 sporadic NETs in the pancreas collected from the NET archives of the departments of pathology in Zürich, Switzerland, and Kiel, Germany, 24 patients (4.5%) suffered from sporadic pancreatic gastrinomas and ZES. These NETs have to be distinguished fromtumors with immunohistochemical positivity for gastrin but without evidence of ZES. An additional 19 patients suffered from MEN1 and ZES. These patients showed exclusively duodenal gastrinomas, but not pancreatic gastrinomas. The prognosis of sporadic and MEN1- associated duodenal gastrinomas is better than that of pancreatic gastrinomas, since they progress slowly to liver metastasis. In summary, sporadic and MEN1- associated gastrinomas in the duodenum and pancreas show different clinico-pathological and genetic features. The incidence of sporadic duodenal gastrin-producing tumors is increasing, possibly due to optimized diagnostic procedures. In contrast, pancreatic MEN1- associated gastrinomas seem to be extremely rare. A considerable subset of tumors with immunohistochemical expression of gastrin but without evidence of ZES should be designated as functionally inactive NETs expressing gastrin, but not as gastrinomas. | Martin Anlauf Nele Garbrecht Tobias Henopp Anja Schmitt Regina Schlenger Andreas Raffel Markus Krausch Oliver Gimm Claus F Eisenberger Wolfram T Knoefel Henning Dralle Paul Komminoth Philipp U Heitz Aurel Perren Günter Klppel | 2006 | World Journal of Gastroenterology2006，12，34： | 7 |
| 12 | 德国和欧洲矿物燃料发电的环境损害代价显示文摘本文分析介绍了德国及欧洲15个国家自1990年以来,矿物燃料发电对大气的污染以及对人类健康和环境的影响。分析研究了燃煤发电的附加成本、对人类健康和环境损害的成本与代价并进行了量化分析。 | Wolfram Krewitt | 2000 | 国际电力2000，4，3： | 7 |
| 13 | Ultrasound enhanced friction stir welding of aluminum and steel: Process and properties of EN AW 6061/DC04-Joints显示文摘In this work, the joining of aluminum to steel was conducted by ultrasound enhanced friction stir welding(USE-FSW). The power ultrasound was introduced into one of the metal sheets by an ultrasonic roll seam module synchronously to the FSW-process. The effect of the ultrasound on the resulting welds, their microstructure and their corrosion properties was investigated by light and scanning electron microscopy and corrosion investigations. The USE-FSW-joints showed less and smaller steel particles in the nugget zone as well as a thinner continuous intermetallic phase of FeAl_3 at the interface. The nondestructive testing method of computed laminography proved the observations made by optic microscopy due to non-porous joints for both techniques. Corrosion investigations showed only low corrosion current densities and no enhanced galvanic corrosion for the EN AW-6061/DC04-hybrid joints in sodium chloride solution. | Marco Thoma Guntram Wagner Benjamin Straβ Bernd Wolter Sigrid Benferc Wolfram Furbeth | 2018 | Journal of Materials Science & Technology2018，34，1： | 6 |
| 14 | BP神经网络在使用红外热像仪技术预测冬小麦产量中的应用(英文)显示文摘通过使用红外热像仪技术获得冬小麦冠层不同温度值,计算得到冬小麦主要需水阶段水分胁迫指标ICWSI(infrared crop water stress index)。并根据此数据,使用一次灌溉周期中3个时段不同的ICWSI的平均值作为输入因子,相应实测冬小麦产量作为输出因子,建立了BP神经网络模型对冬小麦的产量进行预测,本文采用三层BP神经网络,其拓扑结构为3-5-1,数据归一化处理后收敛性能增强。预测结果显示,平均相对误差最大只有3.42%;为了证实这一方法的优越性,同时建立了基于ICWSI和冬小麦产量关系的非线性函数的预测模型,预测结果与实际产量值进行比较,平均相对误差最大达到了18.87%。两种预测方法得到的不同预测结果表明,将红外热像仪技术与BP神经网络预测方法相结合,可以成功用来预测冬小麦产量,比使用非线性函数预测的效果更好,精度更高,可靠性更强,可以用于实际生产需要。 | 胡振方 张录达 王珏璇 Shamaila Z 曾爱君 宋坚利 刘亚佳 Wolfram S Joachim M 何雄奎 | 2013 | 光谱学与光谱分析2013，33，6： | 5 |
| 15 | Occurrence,removal and emission of per-and polyfluorinated alkyl substances(PFASs)from chrome plating industry:A case study in Southeast China显示文摘Per-and polyfluorinated alkyl substances(PFASs)have been used since the 1950s as chrome mist suppressant(CMS)in the electroplating industry.In this study,various samples within an electroplating factory,the related wastewater treatment facilities and surrounding environment at Hangzhou Bay in Southeast China were investigated for the occurrence and removal of PFASs.PFOS and 6:2 Cl-PFAES are predominant compounds in the samples.The PFASs in the bath solution of the workshops had some differences from the final releases,partly because of the historic usage and memory effects.PFOS and 6:2 Cl-PFAES were found in high concentration(5500 and 154.5 mg/L in influent,795 and 985 mg/L in effluent)in the electroplating Wastewater Treatment Plant(WWTP).The ultrafiltration and reverse osmosis(RO)treatment had a significant removal efficiency(74%e100%).On the other hand the reduction,precipitation and anaerobic/anoxic/oxic(A2/O)treatment had poor removal efficiency for PFASs.The receiving river samples had levels of PFASs between 300 and 1500 ng/L,and the concentrations of PFOS and 6:2 Cl-PFAES decreased with increasing distance to the municipal WWTP outlet due to dilution.The concentrations of PFOA in the river water samples were also high but might originate from other sources.The relevant ecological risk is noteworthy,especially for PFOS and PFOA for which limits have been defined.There is an urgent need to control plating industries in China and worldwide.Currently a GEF project related to Stockholm Convention implementation has reduced and possibly eliminated PFOS use and release in the plating industry in China.In addition,it will be important to evaluate and control the alternatives used. | Yingxi Qu Jun Huang Wolfram Willand Roland Weber | 2020 | Emerging Contaminants2020，6，1： | 5 |
| 16 | Statements from the Taormina expert meeting on occult hepatitis B virus infection显示文摘 | Giovanni Raimondo Jean-Pierre Allain Maurizia R. Brunetto Marie-Annick Buendia Ding-Shinn Chen Massimo Colombo Antonio Craxì Francesco Donato Carlo Ferrari Giovanni B. Gaeta Wolfram H. Gerlich Massimo Levrero Stephen Locarnini Thomas Michalak Mario U. Mon | 2008 | Journal of Hepatology2008，，4： | 5 |
| 17 | 曲线锯——提高木材加工能力的新技术显示文摘 | Wolfram Ulrich 吴沂(译) 卢镇华(校) | 2006 | 木工机床2006，，4： | 5 |
| 18 | Small intestine bleeding due to multifocal angiosarcoma显示文摘We report a case of an 84-year-old male patient with primary small intestinal angiosarcoma.The patient initially presented with anemia and melena.Consecutive endoscopy revealed no signs of upper or lower active gastrointestinal bleeding.The patient had been diagnosed 3 years previously with an aortic dilation,which was treated with a stent.Computed tomography suggested an aorto-intestinal fistula as the cause of the intestinal bleeding,leading to operative stent explantation and aortic replacement.However,an aorto-intestinal fistula was not found,and the intestinal bleeding did not arrest postoperatively.The constant need for blood transfusions made an exploratory laparotomy imperative,which showed multiple bleeding sites,predominately in the jejunal wall.A distal loop jejunostomy was conducted to contain the small intestinal bleeding and a segmental resection for histological evaluation was performed.The histological analysis revealed a lessdifferentiated tumor with characteristic CD31,cytokeratin,and vimentin expression,which led to the diagnosis of small intestinal angiosarcoma.Consequently,the infiltrated part of the jejunum was successfully resected in a subsequent operation,and adjuvant chemotherapy with paclitaxel was planned.Angiosarcoma of the small intestine is an extremely rare malignant neoplasm that presents with bleeding and high mortality.Early diagnosis and treatment are essential to improve outcome.A small intestinal angiosarcoma is a challenging diagnosis to make because of its rarity,nonspecific symptoms of altered intestinal function,nonspecific abdominal pain,severe melena,and acute abdominal signs.Therefore,a quick clinical and histological diagnosis and decisive measures including surgery and adjuvant chemotherapy should be the aim. | Luisa Zacarias Fhrding Arne Macher Stefan Braunstein Wolfram Trudo Knoefel Stefan Andreas Topp | 2012 | World Journal of Gastroenterology2012，18，44： | 4 |
| 19 | 微型锂离子电池及关键材料的研究显示文摘当前的微型低能耗电子设备以及微机电系统(MEMS)器件大都使用传统的体积较大的外接电源供能,这就限制了这些微型器件的发展和应用。通过设计集成微型电源并将其与这些微器件一体化,可构筑自主微器件系统。本文主要综述了本课题组开展的与微电子技术兼容的全固态微型锂离子电池的研究,包括LiCoO2正极薄膜材料、固态电解质-电极LiPON/LiCoO2界面的研究以及微型锂离子电池制备工艺等。 | 董全峰 宋杰 郑明森 Susanne Jacke Wolfram Jaegermann | 2011 | 化学进展2011，23，2： | 4 |
| 20 | 全球化视角下的日本足球显示文摘通过对日本足球体制与职业足球实践等方面的分析,探讨了体育运动全球化的理论框架,认为流行时尚和国内政治塑造了日本足球,推动了日本足球的全球化。还探讨了体育文化与政治决策如地区发展规划、城市政策、卫生政策、国家建设等因素之间的相互影响。 | Wolfram Manzenreiter 王宝珠 | 2003 | 体育学刊2003，10，4： | 4 |
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