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| 1 | Predictive value of C-reactive protein/albumin ratio in acute pancreatitis显示文摘BACKGROUND:Serum C-reactive protein(CRP) increases and albumin decreases in patients with inflammation and infection.However,their role in patients with acute pancreatitis is not clear.The present study was to investigate the predictive significance of the CRP/albumin ratio for the prognosis and mortality in acute pancreatitis patients.METHODS:This study was performed retrospectively with 192 acute pancreatitis patients between January 2002 and June 2015.Ranson scores,Atlanta classification and CRP/albumin ratios of the patients were calculated.RESULTS:The CRP/albumin ratio was higher in deceased patients compared to survivors.The CRP/albumin ratio was positively correlated with Ranson score and Atlanta classification in particular and with important prognostic markers such as hospitalization time,CRP and erythrocyte sedimentation rate.In addition to the CRP/albumin ratio,necrotizing pancreatitis type,moderately severe and severe Atlanta classification,and total Ranson score were independent risk factors of mortality.It was found that an increase of 1 unit in the CRP/albumin ratio resulted in an increase of 1.52 times in mortality risk.A prediction value about CRP/albumin ratio >16.28 was found to be a significant marker in predicting mortality with 92.1% sensitivity and 58.0% specificity.It was seen that Ranson and Atlanta classification were higher in patients with CRP/albumin ratio >16.28 compared with those with CRP/albumin ratio ≤16.28.Patients with CRP/albumin ratio >16.28 had a 19.3 times higher chance of death.CONCLUSION:The CRP/albumin ratio is a novel but promising,easy-to-measure,repeatable,non-invasive inflammationbased prognostic score in acute pancreatitis. | Mustafa Kaplan Ihsan Ates Muhammed Yener Akpinar Mahmut Yuksel Ufuk Baris Kuzu Sabite Kacar Orhan Coskun Ertugrul Kayacetin | 2017 | Hepatobiliary & Pancreatic Diseases International2017，16，4： | 53 |
| 2 | Long-term success of ahmed glaucoma valve in refractory glaucoma显示文摘AIM:To evaluate the long-term results and complications of ahmed glaucoma valve (AGV) implantation in refractory glaucoma.· METHODS:A retrospective review of 13 patients (13 eyes) with refractory glaucoma who underwent AGV implantation and had a minimum follow-up of 18 months was performed.All patients underwent a complete ophthalmologic examination and intraocular pressure (IOP) measurement before surgery and at 1 month,3 months,6 months,1 year after surgery and yearly afterwards.Complications and the number of antiglaucoma medications needed were recorded.· RESULTS:Mean age was 27.3±16.0 years.All eyes (100%) had at least one prior incisional surgery.Mean follow-up was 61.3±30.8 months.IOP was reduced from a mean of 35.0±7.0mmHg to 18.2±7.9mmHg at 12 months and to 17.0±4.1mmHg at 96 months (P <0.05) with a lower number of medications from baseline,76.9% patients required additional procedures to achieve the success criteria set by previously published series.The most common complications were encapculated cyst formation in eight eyes (61.5%) and tube exposure in four eyes (30.8%).· CONCLUSION:Encapsulated cyst formation was the most common complication which hindered succesful IOP control after AGV implant insertion for refractory glaucoma.Despite cyst excision with anti-fibrotic agents,successful IOP reduction was not achieved in 76.9% of the patients without antiglaucoma medication. | Mahmut Kaya Zeynep Ozbek Aylin Yaman Ismet Durak | 2012 | International Journal of Ophthalmology(English edition)2012，5，1： | 15 |
| 3 | Left-sided appendicitis:Review of 95 published cases and a case report显示文摘AIM:To give an overview of the literature on left-sided acute appendicitis (LSAA) associated with situs inversus totalis (SIT) and midgut malrotation (MM).METHODS:We present a new case of LSAA with SIT and a literature review of studies published in the English language on LSAA,accessed via PubMed and Google Scholar databases.RESULTS:Ninety-five published cases of LSAA were evaluated and a 25-year-old female,who presented to our clinic with left lower abdominal pain caused by LSAA,is reported.In the reviewed literature,fiftyseven patients were male and 38 were female with an age range of 8 to 82 years and a median age of 29.1 ± 15.9 years.Sixty-six patients had SIT,23 had MM,three had cecal malrotation,and two had a previously unnoted congenital abnormality.Fifty-nine patients had presentedto the hospital with left lower,14 with right lower and seven with bilateral lower quadrant pain,and seven subjects complained of left upper quadrant pain.The diagnosis was established preoperatively in 49 patients,intraoperatively in 19,and during the postoperative period in five;14 patients were aware of having this anomaly.The data of eight patients were not unavailable.Eleven patients underwent laparoscopic appendectomy,which was combined with cholecystectomy in two cases.Histopathological examination of the appendix specimens revealed adenocarcinoma in only two of 95 patients.CONCLUSION:The diagnosis of left lower quadrant pain is based on well-established clinical symptoms,physical examination and physician's experience. | Sami Akbulut Abdullah Ulku Ayhan Senol Mahmut Tas Yusuf Yagmur | 2010 | World Journal of Gastroenterology2010，16，44： | 9 |
| 4 | Microstructure, mechanical properties and formability of friction stir welded dissimilar materials of IF-steel and 6061 Al alloy显示文摘AA 6061 alloy and interstitial-free(IF)steel plates were joined by the friction stir welding(FSW)method,and the microstructure,mechanical properties,and biaxial stretch formability of the friction stir welded(FSWed)parts were investigated.The results indicate that the FSWed parts showed optimum tensile strength during FSW with the 0.4-mm offset position of the tool.The Fe4Al13 intermetallic compound formed in the defect-free intersection of AA 6061 and IF-steel plates during FSW.The hardness of the IF-steel part of the FSWed region increased almost 90%relative to its initial hardness of HV0.2 105.The tensile and yield strengths of FSWed regions were approximately 170 MPa and 145 MPa,respectively.According to the formability tests,the Erichsen Index(EI)of the IF-steel,AA 6061,and the FSWed samples were determined to be 2.9 mm,1.9 mm,and 2.1 mm,respectively.The EI of the FSWed sample was almost the same as that of the AA 6061 alloy.However,it decreased compared with that of the IF-steel.The force at EI(FEI)was approximately 1180 N for the FSWed condition.This value is approximately 70%higher than that of AA 6061 alloy. | Semih Mahmut Aktarer Dursun Murat Sekban Tevfik Kucukomeroglu Gencaga Purcek | 2019 | International Journal of Minerals,Metallurgy and Materials2019，26，6： | 7 |
| 5 | Effect of Salt Stress on Photosynthetic GasExchange and Chlorophyll FluorescenceParameters in Alhagi pseudalhagi显示文摘Soil salinity is one of the most important environmental factors limiting plant growth and productivity in many regions in the world. Salt stress directly affects plant photosynthesis, which is an important physiological process to limit plant growth and crop yield. But the effects of salt stress on the mechanism of the photosynthesis is still not clear. In this experiment, the salt tolerant plant Alhagi pseudalhagi was selected as the experiment material, and the salt sensitive plant Vigna radiata as the control, to explore the effects of salt stress on photosynthetic parameters of A. pseudalhagi. Plants were grown in a greenhouse,cultured with 1/2 Hoagland nutrient solution, treated by 0(control), 50, 100 or 200 s of mmol/L of NaCl solution for 12 d. Then,the chlorophyll contents, gas exchange parameters and chlorophyll a fluorescence in each treatment were measured. The results showed that under the salt stress simulated by 50 mmol/L NaCl, the net photosynthetic rate(Pn) and stomatal conductance(gs)of A. pseudalhagi were significantly increased compared with the control, while intercellular CO_2 concentration(Ci) was significantly decreased, Fv'/Fm', Fv/Fm and Fv/Fo were increased over time, but had no significant differences with the control ФPSⅡ,ETR and qP were significantly increased, and NPQ was significantly decreased. Under the salt stress simulated by 100 and 200mmol/L NaCl, Fv'/Fm', Fv/Fm, Fv/Fo, ФPSⅡ and qP of A. pseudalhagi were gradually decreased over time. In contrary, under the salt stress simulated by 50 and 100 mmol/L NaCl, the Pn, gs, Ci, Fv'/Fm', Fv/Fm, Fv/Fo, ФPSII, qP and ETR were all significantly decreased, while NPQ was significantly increased. | Mahmut SHAWKAT Mansur NASIR Qijun CHEN Halil KURBAN | 2017 | Agricultural Science & Technology2017，18，3： | 6 |
| 6 | Enhancement of pacemaker induced stochastic resonance by an autapse in a scale-free neuronal network显示文摘An autapse is an unusual synapse that occurs between the axon and the soma of the same neuron. Mathematically, it can be described as a self-delayed feedback loop that is defined by a specific time-delay and the so-called autaptic coupling strength. Recently, the role and function of autapses within the nervous system has been studied extensively. Here, we extend the scope of theoretical research by investigating the effects of an autapse on the transmission of a weak localized pacemaker activity in a scale-free neuronal network. Our results reveal that by mediating the spiking activity of the pacemaker neuron, an autapse increases the propagation of its rhythm across the whole network, if only the autaptic time delay and the autaptic coupling strength are properly adjusted. We show that the autapse-induced enhancement of the transmission of pacemaker activity occurs only when the autaptic time delay is close to an integer multiple of the intrinsic oscillation time of the neurons that form the network. In particular, we demonstrate the emergence of multiple resonances involving the weak signal, the intrinsic oscillations, and the time scale that is dictated by the autapse. Interestingly, we also show that the enhancement of the pacemaker rhythm across the network is the strongest if the degree of the pacemaker neuron is lowest. This is because the dissipation of the localized rhythm is contained to the few directly linked neurons, and only afterwards, through the secondary neurons, it propagates further. If the pacemaker neuron has a high degree, then its rhythm is simply too weak to excite all the neighboring neurons, and propagation therefore fails. | YILMAZ Ergin BAYSAL Veli PERC Matjaz OZER Mahmut | 2016 | Science China(Technological Sciences)2016，59，3： | 6 |
| 7 | Impact of admission blood glucose levels on prognosis of elderly patients with ST elevation myocardial infarction treated by primary percutaneous coronary intervention显示文摘OBJECTIVE:Admission hyperglycemia in acute myocardial infarction (MI) is related with increased in-hospital and long term mortality and major cardiac adverse events。 We aimed to investigate how admission hyperglycemia affects the short and long term outcomes in elderly patients >65 years) after primary percutaneous coronary intervention for ST elevation myocardial infarction。 METHODS:We retrospectively analyzed 677 consecutive elderly patients (mean age 72.2 ±5.4)。 Patients were divided into two groups according to admission blood glucose levels。 Group : low glucose group (LLG), glucose < 168 mg/dL; and Group 2: high glucose group (HGG), glucose >168 mg/dL。 RESULTS:In-hospital, long term mortality and in-hospital major adverse cardiac events were higher in the high admission blood glucose group (P <0.001)。 Multivariate regression analysis showed: Killip > 1, post-thrombolysis in MI <3 and admission blood glucose levels were independent predictors of in-hospital adverse cardiac events (P <0.001)。 CONCLUSIONS:Admission hyperglycemia in elderly patients presented with ST elevation myocardial infarction is an independent predictor of in-hospital major adverse cardiac events and is associated with in-hospital and long term mortality。 | Ahmet Ekmekci Mahmut Uluganyan Fatif Tufan Huseyin Uyarel Gurkan Karaca Seref Kul Barl(s) Gungor | 2013 | Journal of Geriatric Cardiology2013，10，4： | 6 |
| 8 | Genetic consequences of postglacial colonization by the endemic Yarkand hare (Lepus yarkandensis) of the arid Tarim Basin显示文摘Orogenesis of the Qinghai-Tibetan Plateau,which occurred in a stepwise manner,contributed to the extreme aridity of the Tarim Basin,resulting in vulnerable and unstable ecosystems.Quaternary climatic oscillations may have affected the ecosystems and,consequently,the distributions and genetic structuring of the Tarim Basin's biota.We used nucleotide sequence data from 2 mitochondrial (mt) DNA genes (Cyt b and the D-loop) to test hypotheses associated with the matrilineal and demographical histories of the Tarim Basin's endemic Yarkand hare (Lepus yarkandensis).Range-wide sampling involving 20 populations and 224 individuals detected 126 haplotypes that clustered into 5 major lineages in both the phylogenetic tree and median-joining network.Populations from the northern and eastern Tarim Basin shared a similar history,as did those from the western and southern regions.Demographical analysis and genetic diversity estimations suggested that the western and southern regions might have served as glacial refugia for the Yarkand hare during Quaternary climatic oscillations.The distribution of the Yarkand hare,especially in the northern and eastern parts,probably represented 3 postglacial colonization events,dated to 0.21,0.090 and 0.054 MYA,which corresponded to known interglacial periods.Given the relatively complete geographic isolation between the eastern and southern populations,the Yarkand hare likely dispersed during postglacial periods from the southwest to the north,and then onward to the east.The absence of water likely forced the species into refugia,and this differed from other Pleistocene biogeographical drivers.The demographical and historical patterns have important implications for conservation. | SHAN WenJuan LIU Jiang YU Li ROBERT W. Murphy MAHMUT Halik ZHANG YaPing | 2011 | Chinese Science Bulletin2011，56，13： | 5 |
| 9 | 随机预定需求下的客房分配:酒店收益管理博弈显示文摘本文研究具有两个不同消费级别的两家酒店在完全信息条件下收益管理的单期静态博弈。讨论了酒店分别在竞争与合作两种情况下,对于低价房间预留数目的设定策略。在竞争情况下,证明了纳什均衡唯一解的存在性。在合作情况下,分析了两酒店的节省成本及目标函数的凹性。在合作情况下,提出了使两酒店总收益大幅度提高的条件。最后,用一些算例(假设客房预定需求变量服从截断正态分布)分析了在每种情况下的酒店最优管理方案。 | 宋敬普 Mahmut Parlar | 2012 | 国际商务研究2012，33，3： | 5 |
| 10 | Unusual histopathological findings in appendectomy specimens:A retrospective analysis and literature review显示文摘AIM: To document unusual findings in appendectomy specimens. METHODS: The clinicopathological data of 5262 patients who underwent appendectomies for presumed acute appendicitis from January 2006 to October 2010 were reviewed retrospectively. Appendectomies performed as incidental procedures during some other operation were excluded. We focused on 54 patients who had unusual findings in their appendectomy specimens. We conducted a literature review via the PubMed and Google Scholar databases of English language studies published between 2000 and 2010 on unusual findings in appendectomy specimens. RESULTS: Unusual findings were determined in 54 (1%) cases by histopathology. Thirty were male and 24 were female with ages ranging from 15 to 84 years (median, 32.2 ± 15.1 years). Final pathology revealed 37 cases of enterobiasis, five cases of carcinoids, four mucinous cystadenomas, two eosinophilic infiltrations, two mucoceles, two tuberculosis, one goblet-cell carcinoid, and one neurogenic hyperplasia. While 52 patients underwent a standard appendectomy, two patients who were diagnosed with tuberculous appendicitis underwent a right hemicolectomy. All tumors were located at the distal part of the appendix with a mean diameter of 6.8 mm (range, 4-10 mm). All patients with tumors were alive and disease-free during a mean follow-up of 17.8 mo. A review of 1366 cases reported in the English literature is also discussed. CONCLUSION: Although unusual pathological findings are seldom seen during an appendectomy, all appendectomy specimens should be sent for routine histopathological examination. | Sami Akbulut Mahmut Tas Nilgun Sogutcu Zulfu Arikanoglu Murat Basbug Abdullah Ulku Heybet Semur Yusuf Yagmur | 2011 | World Journal of Gastroenterology2011，17，15： | 4 |
| 11 | Evaluation of dry eye disease in newly diagnosed anxiety and depression patients using anterior segment optical coherence tomography显示文摘Background:We aimed to evaluate dry eye diseases(DED)in patients with newly diagnosed depression and anxiety patients.Methods:Forty newly diagnosed depression,35 anxiety patients,and 37 controls without any history of taking psychiatric drugs(or before the beginning of psychiatric medication)and topical ophthalmic drop use,were included in the study.All depression and anxiety diagnoses were performed by an experienced psychiatrist.Beck depression and anxiety tests were used to measure disease severity.Tear film break up time(TBUT),Schirmer’s test,Oxford scores and ocular surface disease index(OSDI)were admiinistered to participants.Anterior segment optical coherence tomography was used to measure tear meniscus heights(TMH),tear meniscus depths(TMD)and tear meniscus areas(TMA).Results:In anxiety and depression groups,Schirmer’s test(mm)(7.24±6.02,6.58±4.9 and 18.79±4.9 respectively,p<0.05)and TBUT(s)(5.62±3.1,5.6±3.5 and 13.37±1.7 respectively,p<0.05)were significantly lower than control group.In addition,OSDI and Oxford scores were significantly higher than controls.OSDI scores were 28.01±19,30.43±18.49,14.38±8.14 respectively(p=0.002)and Oxford scores were 1.9±0.7,2.1±0.6 and 0.7±0.4 respectively(p=0.001).TMD,TMH and TMA values were significantly lower in anxiety and depression groups compared with control groups.Correlations between disease inventory scores and dry eye tests were detected.Conclusions:This study showed a relation between DED and newly diagnosed anxiety and depression patients with no history of psychiatric drug use.The presence of correlation between dry eye tests and disease inventory scores strengthens this association.This is an important knowledge that need to be evaluated in these patients before starting psychiatric medication. | Mahmut Oğuz Ulusoy Selen Işık-Ulusoy SertaçArgun Kıvanç | 2019 | Eye and Vision2019，6，1： | 3 |
| 12 | In vitro effect of pantoprazole on lower esophageal sphincter tone in rats显示文摘AIM:To investigate the in vitro effects of pantoprazole on rat lower esophageal sphincter(LES)tone.METHODS:Rats weighing 250-300 g,provided by the Yeditepe University Experimental Research Center(Yü-DETAM),were used throughout the study.They were anesthetized before decapitation.LES tissues whose mucosal lining were removed were placed in a stan-dard 30-mL organ bath with a modif ied Krebs solution and continuously aerated with 95% oxygen-5% carbon dioxide gas mixture and kept at room temperature.The tissues were allowed to stabilize for 60 min.Sub-sequently,the contractile response to 10-6 mol/L carba-chol was obtained.Different concentrations of freshly prepared pantoprazole were added directly to the tis-sue bath to generate cumulative concentrations of 5×10-6 mol/L,5×10-5 mol/L,and 1.5×10-4 mol/L.Activi-ties were recorded on an online computer via a 4-channeltransducer data acquisition system using the software BSL PRO v 3.7,which also analyzed the data.RESULTS:Pantoprazole at 5×10-6 mol/L caused a small,but statistically insignif icant,relaxation in the car-bachol-contracted LES(2.23% vs 3.95%).The 5×10-5 mol/L concentration,however,caused a signif icant relax-ation of 10.47% compared with the control.1.5×10-4 mol/L concentration of pantoprazol caused a 19.89% relaxation in the carbachol contracted LES(P<0.001).CONCLUSION:This is the fi rst study to demonstrate that pantoprazole has a relaxing effect in isolated LESs.These results might have signif icant clinical implications for the subset of patients using proton pump inhibitors who do not receive full symptomatic alleviation from gastroesophageal reflux disease. | Mustafa Duman Mahmut zer Enver Rean Yeliz Demirci Ali E Atιcι Tahsin Dalgι Erdal B Bostancι Ece Gen | 2011 | World Journal of Gastroenterology2011，17，46： | 3 |
| 13 | Ahmed青光眼阀治疗难治性青光眼的长期疗效(英文)显示文摘评估Ahmed青光眼阀(Ahmed glaucoma valve,AGV)植入治疗难治性青光眼的长期疗效及并发症。方法:回顾性分析13例13眼接受Ahmed青光眼阀植入,最短随访18mo的难治性青光眼患者。所有患者均在术前及术后1,3,6mo,1a及1a以后行全面的眼科检查,眼压测量,记录并发症及抗青光眼的药物需求。结果:患者平均年龄27.3±16.0岁。所有患眼(100%)接受至少一次前置小切口手术。平均随访61.3±30.8mo。在少量药物的作用下,12mo时眼压由35.0±7.0mmHg降至18.2±7.9mmHg,96mo时降至17.0±4.1mmHg,76.9%患者需其他辅助治疗以达到预期的成功疗效。最常见的并发症包括包裹性囊肿8眼(61.5%),置管脱出4眼(30.8%)。结论:包裹性囊肿是最常见的并发症,阻碍了Ahmed青光眼阀植入治疗难治性青光眼。虽然囊肿被抗纤维化药物切除,但没有抗青光眼药物的治疗,眼压仍旧不能很好控制。 | Mahmut Kaya Zeynep Ozbek Aylin Yaman Ismet Durak | 2012 | 国际眼科杂志2012，12，7： | 3 |
| 14 | Comparative WGBS identifies genes that influence non-ripe phenotype in tomato epimutant Colourless non-ripening显示文摘Whole-genome bisulfite sequencing(WGBS)allows single-base resolution and genome-wide profiling of DNA methylation in plants and animals.This technology provides a powerful tool to identify genes that are potentially controlled by dynamic changes of DNA methylation and demethylation.However,naturally occurring epimutants are rare and genes under epigenetic regulation as well as their biological relevances are often difficult to define.In tomato,fruit development and ripening are a complex process that involves epigenetic control.We have taken the advantage of the tomato epimutant Colourless non-ripening(Cnr)and performed comparative mining of the WGBS datasets for the Cnr and Sl CMT3-silenced Cnr fruits.We compared DNA methylation profiles for the promoter sequences of approximately 5,000 bp immediately upstream of the coding region of a list of20 genes.Differentially methylated regions were found for some of these genes.Virus-induced gene silencing(VIGS)of differentially methylated gene Sl DET1 or Sl PDS resulted in unusual brown pigmentation in Cnr fruits.These results suggest that comparative WGBS coupled with VIGS can be used to identify genes that may contribute to the colourless unripe phenotype of fruit in the Cnr epimutant. | Weiwei Chen Zhiming Yu Junhua Kong Hui Wang Yichen Li Mei Zhao Xiaohong Wang Qianqian Zheng Nongnong Shi Pengcheng Zhang Silin Zhong Paul Hunter Mahmut Tor Yiguo Hong | 2018 | Science China(Life Sciences)2018，61，2： | 3 |
| 15 | Impact of laparoscopic surgery on bladder and sexual function after total mesorectal excision for rectal cancer显示文摘 | Oktar Asoglu Tugba Matlim Hasan Karanlik Murat Atar Mahmut Muslumanoglu Yersu Kapran Abdullah Igci Vahit Ozmen Mustafa Kecer Mesut Parlak | 2009 | Surgical Endoscopy2009，，2： | 2 |
| 16 | Profiles of serum microRNAs; miR-125b-5p and miR223-3p serve as novel biomarkers for HBV-positive hepatocellular carcinoma显示文摘 | Burcu Gurer Giray Gurol Emekdas Seda Tezcan Mahmut Ulger Mehmet Sami Serin Orhan Sezgin Engin Altintas Eyup Naci Tiftik | 2014 | Molecular Biology Reports2014，，7： | 2 |
| 17 | Can biliary-cyst communication be predicted before surgery for hepatic hydatid disease: does size matter?显示文摘 | Mehmet Kilic Omer Yoldas Mahmut Koc Mehmet Keskek Nazile Karakose Tamer Ertan Erdal Gocmen Mesut Tez | 2008 | The American Journal of Surgery2008，，5： | 2 |
| 18 | High-Performance 3-D Fiber Network Composite Electrolyte Enabled with Li-Ion Conducting Nanofibers and Amorphous PEO-Based Cross-Linked Polymer for Ambient All-Solid-State Lithium-Metal Batteries显示文摘Solid electrolytes have gained attention recently for the development of next-generation Li-ion batteries since they can fun-damentally improve the battery stability and safety.Among various types of solid electrolytes,composite solid electrolytes(CSEs)exhibit both high ionic conductivity and excellent interfacial contact with the electrodes.Incorporating active nanofib-ers into the polymer matrix demonstrates an effective method to fabricate CSEs.However,current CSEs based on traditional poly(ethylene oxide)(PEO)polymer suffer from the poor ionic conductivity of PEO and agglomeration effect of inorganic fillers at high concentrations,which limit further improvements in Li+conductivity and electrochemical stability.Herein,we synthesize a novel PEO based cross-linked polymer(CLP)as the polymer matrix with naturally amorphous structure and high room-temperature ionic conductivity of 2.40×10^(−4)S cm^(−1).Li_(0.3)La_(0.557)TiO_(3)(LLTO)nanofibers are incorporated into the CLP matrix to form composite solid electrolytes,achieving enhanced ionic conductivity without showing filler agglomeration.The high content of Li-conductive nanofibers improves the mechanical strength,ensures the conductive network,and increases the total Li+conductivity to 3.31×10^(−4)S cm^(−1).The all-solid-state Li|LiFePO_(4)batteries with LLTO nanofiber-incorporated CSEs are able to deliver attractive specific capacity of 147 mAh g^(−1)at room temperature,and no evident dendrite is found at the anode/electrolyte interface after 100 cycles. | Chaoyi Yan Pei Zhu Hao Jia Jiadeng Zhu R.Kalai Selvan Ya Li Xia Dong Zhuang Du Indunil Angunawela Nianqiang Wu Mahmut Dirican Xiangwu Zhang | 2019 | Advanced Fiber Materials2019，1，1： | 2 |
| 19 | Outcome and prognostic factors in 110 consecutive patients with primary uterine leiomyosarcoma:A Rare Cancer Network study显示文摘Objective: Primary uterine leiomyosarcomas(ULMS) are rare,and the optimal treatment is controversial.We aimed to assess the outcome and prognostic factors in a multicenter population of women treated for primary ULMS.Methods: We retrospectively collected data of 110 women treated in 19 institutions of the Rare Cancer Network(RCN).Inclusion criteria consisted of a pathology report confirming the diagnosis of ULMS,aged 18–80 years,complete International Federation of Gynecology and Obstetrics(FIGO) stage information,complete information on treatment,and a minimum follow-up of 6 months.Local control(LC) and locoregional control(LRC),overall survival(OS) and disease-free survival(DFS) rates were computed using the Kaplan-Meier method.Univariate analysis was implemented using the log rank test,and multivariate analysis using the Cox model.Results: All patients underwent surgery.Seventy-five patients(68%) received adjuvant radiotherapy(RT),including brachytherapy in 18(16%).Seventeen patients(15%) received adjuvant chemotherapy.Median follow-up was 58(range,6–240) months.Five-year OS and DFS rates were 50% and 34%,and LC and LRC rates were 88%and 72%,respectively.On multivariate analysis,independent favorable prognostic factors were younger age,FIGO stage I,small tumor size,previous uterine disease,and no vascular invasion for OS and DFS.FIGO stage was the only favorable factor influencing LRC.Adjuvant local or systemic treatments did not improve the outcomes.Eight patients treated with RT presented a grade 3 acute toxicity,and only one patient with grade 3 late toxicity.Conclusions: In this large population of primary ULMS patients,we found good results in terms of LC and LRC.Nevertheless,OS remains poor,mainly due to the occurrence of distant metastases.An early diagnosis seemed to improve the prognosis of the patients.Adjuvant local or systemic treatments,or more aggressive surgicalprocedures such as the Wertheim procedure,did not seem to impact the outcome. | Alessandra Franzetti Pellanda Berardino De Bari Elisabeth Deniaud-Alexandre MarcoKrengli Paul Van Houtte Antonella Riehetti Salvador Villa Hadassah Goldberg EwaSzutowiez-Zielifiska Michel Bolla Heidi Rutten Marc Van Eijkeren Philip Poortmans Guido Henke Yavuz Anaeak Steve Chan Christine Landmann Carine Kirkove LueianoScandolaro Jacques Bernier Rene-Olivier Mirimanof Mahmut Ozsahin | 2017 | Chinese Journal of Cancer Research2017，29，6： | 2 |
| 20 | Recent Advances of Metal-Organic Frameworks-based Nanozymes for Bio-applications显示文摘Artificial nanoenzymes with enzyme-like catalytic activity have gradually become an alternative to natural enzymes due to their low production cost,high stability,and good tolerance.In recent years,various enzyme mimics have emerged with the rapid development of nano-teclnology.Metal-organic frameworks(MOFs)are a novel class of porous inorganic-organic hybrid materials made from metal ions/clusters and organic ligands,and MOFs-based nanozymes show great prospect in biosensing,biocatalysis,biomedical imaging,and therapeutic applications,due to unique properties,such as high specific surface area,high porosity,tunable morphology,and excellent biocatalytic properties.In this paper,the recent progresses concerning MOFs-based nanozymes are systematically summarized,including the synthesis,design strategies and related applications,which are divided into two major categories,namely,MOFs structured nanoenzymes and MOFs composite structured nanoenzymes.Meanwhile,the applications of various classifications of MOFs research are introduced.At the end,current challenges and future perspectives of MOFs-based nanozymes are also discussed.It is highly expected that this review on this important area can provide a meaningful guidance for tumor therapy,biosensing and other aspects. | WANG Yuda ZULPYA Mahmut ZHANG Xinyao XU Shihan SUN Jiao DONG Biao | 2022 | Chemical Research in Chinese Universities2022，38，6： | 2 |
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