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| 1 | Histopathological comparison of topical therapy modalities for acute radiation proctitis in an experimental rat model显示文摘瞄准:与福尔马林相比评估为尖锐放射直肠炎的治疗可得到的流行热门治疗学的形式。方法:120 只老鼠的一个总数被使用。四个组(n = 30 ) 为每下列应用治疗形式与一个组一起被分析:控制, mesalazine,福尔马林, betamethasone,和 misoprostol。17.5 Gy 的单个部分被送到每只老鼠。在组老鼠被给 saline 的控制的老鼠,和在另外的三个组的老鼠在照耀以后开始第一天直到无痛苦的死亡的日子的一天收到了适当灌肠剂两次。在 d 上 5, 10,和 15,从每个组的十只老鼠是 euthanized,不知道处理赋值的一个病理学家用一个得分系统检验了直肠。结果:为表面上皮,腺(地窟) 和直肠的薄板 propria 基质的组织病理学说的分数在 d 上到达了他们的最大的水平 10。控制和福尔马林组有最高并且有的 mesalazine 最低,分别地在 d 上 10。在第 15 d 上, mesalazine, betamethasone,和 misoprostol 有 betamethasone 的最低分数。结论:Mesalazine, betamethasone,和 misoprostol 是最好的热门代理人因为放射直肠炎和福尔马林有煽动性的效果并且不应该被使用。 | Cagatay Korkut Oktar Asoglu Murat Aksoy Yersu Kapran Hatice Bilge Nese Kiremit-Korkut Mesut Parlak | 2006 | World Journal of Gastroenterology2006，12，30： | 18 |
| 2 | Neoadjuvant hyperfractionated accelerated radiotherapy plus concomitant 5-fluorouracil infusion in locally advanced rectal cancer: A phase Ⅱ study显示文摘AIM To evaluate the efficacy and tolerability of neoadjuvant hyperfractionated accelerated radiotherapy(HART)and concurrent chemotherapy in patients with locally advanced infraperitoneal rectal cancer. METHODS A total of 30 patients with histopathologically confirmed T2-3/N0+ infraperitoneal adenocarcinoma of rectum cancer patients received preoperative 42 Gy/1.5 Gy/18 days/bid radiotherapy and continuous infusion of 5-fluorouracil(325 mg/m^2). All patients were operated 4-8 wk after neoadjuvant concomitant therapy. RESULTS In the early phase of treatment, 6 patients had grade Ⅲ-Ⅳ gastrointestinal toxicity, 2 patients had grade Ⅲ-Ⅳ hematologic toxicity, and 1 patient had grade Ⅴ toxicity due to postoperative sepsis during chemotherapy. Only 1 patient had radiotherapy-related late side effects, i.e., grade Ⅳ tenesmus. Complete pathological response was achieved in 6 patients(21%), while near-complete pathological response was obtained in 9(31%). After a median follow-up period of 60 mo, the local tumor control rate was 96.6%. In 13 patients, distant metastasis occurred. Disease-free survival rates at 2 and 5 years were 63.3% and 53%, and corresponding overall survival rates were 70% and 53.1%, respectively.CONCLUSION Although it has excellent local control and complete pathological response rates, neoadjuvant HART concurrent chemotherapy appears to not be a feasible treatment regimen in locally advanced rectal cancer, having high perioperative complication and intolerable side effects. Effects of reduced 5-fluorouracil dose or omission of chemotherapy with the aim of reducing toxicity may be examined in further studies. | Zeynep Gural Sezer Saglam Serap Yucel Esra Kaytan-Saglam Oktar Asoglu Cetin Ordu Hediye Acun Rasul Sharifov Semen Onder Ahmet Kizir Ethem N Oral | 2018 | World Journal of Gastrointestinal Oncology2018，10，1： | 3 |
| 3 | Impact of laparoscopic surgery on bladder and sexual function after total mesorectal excision for rectal cancer显示文摘 | Oktar Asoglu Tugba Matlim Hasan Karanlik Murat Atar Mahmut Muslumanoglu Yersu Kapran Abdullah Igci Vahit Ozmen Mustafa Kecer Mesut Parlak | 2009 | Surgical Endoscopy2009，，2： | 2 |
| 4 | Prognostic and predictive factors after surgical treatment for locally recurrent rectal cancer:, a single institute experience 显示文摘 | Asoglu O Karanlik H Muslumanoglu M | 2007 | Eur J Surg Oncol2007，33，10： | 1 |
| 5 | Laparoscopic treatment of mesenterie cysts显示文摘 | Asoglu O lgci A Karanlik H | 2003 | Surgical Endoscopy2003，17，5： | 1 |
| 6 | Does the complication rate increase in laparoscopic cholecystectomy for acute cholecystitis 显示文摘 | Asoglu O Ozmen V Karanlik H | 2004 | Laparoendosc Adv Surg Tech A2004，14，2： | 1 |
| 7 | Does the complication rate increase in laparoscopie cholecystectomy for acute cholecyslitis 显示文摘 | Asoglu O Ozrnan V Karanlik H | 2004 | Acta Chit Hung J Laparoendose Adv Surg Tect A2004，14，2： | 1 |
| 8 | Metastatic lymph node ratio is an independent prognostic factor in gastric cancer显示文摘 | Asoglu O Karanlik H Parlak M | 2009 | Hepatogastroenterology2009，56，9192： | 1 |
| 9 | Does the complication rate increase in laparoscopic cholecystectomy for acute cholecystitis显示文摘 | Asoglu O Ozmen V Karanlik H | 2004 | Laparoendosc Adv Surg Tech A2004，14，3： | 1 |
| 10 | Does the complication rate increase in laparoscopic cholecystectomy for acute cholecystitis显示文摘 | Asoglu O Ozmen V Karanlik H | 2004 | Laparoendosc Adv Surg Tech A2004，14，2： | 1 |
| 11 | Impact of laparoscopic surgery on bladder and sexual function after total mesorectal excision for rectal cancer显示文摘 | Asoglu O Matlim T Karanlik H | 2009 | Surg Endosc2009，23，2： | 1 |
| 12 | Does the complication rate increase in laparoscopic cholecystectomy for acute cholecystitis显示文摘 | Asoglu O Ozmen V Karanlik H | 2004 | J Laparoendosc Adv Surg Tech A2004，14，2： | 1 |
| 13 | Standardized laparoscop-ic sphincter-preserving total mesorectal excision for rectal cancer:long-term oncologic outcome in 217 unselected consecutive patients显示文摘 | Asoglu O Kunduz E Rahmi Serin K | 2014 | Suig Laparosc Endosc Percutan Tech2014，24，2： | 1 |
| 14 | Risk Factors for Recurrence and Death After Primary Surgical Treatment of Malignant Phyllodes Tumors显示文摘 | Oktar Asoglu MD Mustafa M. Ugurlu MD Kay Blanchard MD Clive S. Grant MD Carol Reynolds MD Steven S. Cha MS John H. Donohue MD | 2004 | Annals of Surgical Oncology2004，，11： | 1 |
| 15 | Effects of Surgical Laparoscopic Experience on the Short-term Postoperative Outcome of Rectal Cancer: Results of a High Volume Single Center Institution显示文摘 | Emre Balik Oktar Asoglu Sezer Saglam Sumer Yamaner Ali Akyuz Yilmaz Buyukuncu Mine Gulluoglu Turker Bulut Dursun Bugra | 2010 | Surgical Laparoscopy Endoscopy & Percutaneous Techniques2010，，2： | 1 |
| 16 | Feasibility of surgicalmanagement in patients with granulomatous mastitis 显示文摘 | Asoglu 0 Ozmen V Karanlik H | 2005 | BreastJ2005，11，2： | 1 |
| 17 | Impact of laparoscopic surgery on bladder and sexual function after total mesorectal exci- sion for rectal cancer 显示文摘 | Asoglu O Matlim T Karanlik H | 2009 | Surg Endosc2009，23，2： | 1 |
| 18 | Does the complication rate increase in laparoscopic cholecystectomy for acute cholecystitis显示文摘 | Asoglu O Ozmen V Karanlik H | 2004 | Laparoendosc Adc Surg Tech A2004，14，2： | 1 |
| 19 | Breast conserving surgery after primary chemotherapy in locally advanced breast cancer显示文摘 | Asoglu O Muslumanoglu M Igci A | 2005 | Acta Chir Belg2005，105，1： | 1 |
| 20 | Does the complication rate increase in laparoscopic cholecystectomy for acute cholecystitis?显示文摘 | Asoglu O Ozmen V Karanlik H | 2004 | J Laparoendosc Adv Surg Tech A2004，14，2： | 1 |
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