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1NKT cell subsets as key participants in liver physiology and pathology显示文摘自然漂亮 T (NKT ) 房间是通常认出类脂化合物抗原的象天生一样淋巴细胞并且在肝的 microvascular 分隔空间被充实。NKT 房间能被自我类脂化合物或微生物引起类脂化合物的抗原并且由通过像使用费的受体发信号激活。后面的激活, NKT 房间很快分泌支持 inflammatory 或反煽动性的 cytokines 和 chemokines,并且从而为随后的免疫或忍耐决定周围。这正在变得清楚 NKT cells— 的二个不同子集;类型我和类型 II—有抗原识别的不同模式并且让在煽动性的肝疾病反对角色。这里,我们在肝主要集中于两个 NKT 房间子集的角色在有免疫力的忍耐和煽动性的疾病的维护。而且,怎么我和类型 II NKT 房间影响的类型的微分激活到在为织物正直的重要后果的结果的另外的天生的房间和适应有免疫力的房间被讨论。包括 CD1d tetramers,更好的试剂在临床的研究被使用在病人在肝疾病定义 NKT 房间的角色,是关键的。Keya Bandyopadhyay Idania Marrero Vipin Kumar 2016Cellular & Molecular Immunology2016,13,3:23
2A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C显示文摘Chun-Tao Wai Joel K. Greenson Robert J. Fontana John D. Kalbfleisch Jorge A. Marrero Hari S. Conjeevaram Anna S.-F. Lok 2003Hepatology2003,,2:11
3Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma: Subanalyses of a phase III trial显示文摘Jordi Bruix Jean-Luc Raoul Morris Sherman Vincenzo Mazzaferro Luigi Bolondi Antonio Craxi Peter R. Galle Armando Santoro Michel Beaugrand Angelo Sangiovanni Camillo Porta Guido Gerken Jorge A. Marrero Andrea Nadel Michael Shan Marius Moscovici Dimitris Vo 2012Journal of Hepatology2012,,4:6
4Feeding of yeast(Candida spp.) improves in vitro ruminal fermentation of fibrous substrates显示文摘In vitro gas production technique(IVGPT) was used with the objective of determining the inclusion effect of live cells of two strains of Candida yeast on in vitro ruminal fermentation of two fibrous substrates. In order to achieve this, two experiments were performed: A) using oat straw(Avena sativa) as substrate; B) using alfalfa hay(Medicabo sativa) as substrate, comparing the effect of two different strains of Candida genre, both isolated from the rumen, on the mentioned substrates. Levica 25(Candida tropicalis) yeast belongs to the culture collection of the Institute of Animal Science, Cuba, and Levazoot 15(Candida norvegensis) yeast is part of the collection of the Faculty of Zootechnology and Ecology of the Autonomous University of Chihuahua, Mexico. Both strains demonstrated their potential in activating the ruminal fermentation. They stimulated(P<0.0001) the ruminal fermentation of the substrates under study. However, the Levazoot strain stimulated the dry matter(DM) fermentation of alfalfa in 21.43%, more than Levica 25. It is concluded that there is an influence of yeast strain and diet on the rumen environment and, therefore, it is important to select the appropriate strain in every production condition.Yoandra Marrero Yamicela Castillo Oscar Ruiz Eduviges Burrola Claudio Angulo 2015Journal of Integrative Agriculture2015,14,3:6
5GP73, a resident Golgi glycoprotein, is a novel serum marker for hepatocellular carcinoma显示文摘Jorge A. Marrero Patrick R. Romano Olga Nikolaeva Laura Steel Anand Mehta Claus J. Fimmel Mary Ann Comunale Anthony D’Amelio Anna S. Lok Timothy M. Block 2005Journal of Hepatology2005,,6:5
6Diabetic gastroenteropathy:An underdiagnosed complication显示文摘This article is an extensive review that provides an update on the pathophysiology,symptoms,diagnosis,and treatment of diabetic gastroenteropathy.There is no reported prevalence,but it has been described that patients with type 1 diabetes have a cumulative incidence at 10 years of 5.2%,and type 2 patients,1%.Also,in the group of type 1 diabetes,it has been observed that women are more likely to present this condition(5.8%vs 3.5%).Many factors are associate with its development(e.g.,hyperglycemia,vagal dysfunction,loss of expression of neural nitric oxide synthase in the myenteric plexus,alterations in the Cajal interstitial cell network,and oxidative stress).Gastrointestinal discomfort could be perceived 70% higher in diabetic patients,describing that 25%of diabetic patients experience gastrointestinal symptoms.Diabetic enteropathy could affect any portion of the gastrointestinal tract,but esophageal alterations were described in more than 60% of diabetic patients,also 60% of them present constipation,and 20%,diarrhea.Gastric emptying scintigraphy is useful to evaluate gastroparesis,therefore,gastric retention of more than 60%at 2 h has a sensitivity of 100% and specificity of 20% for diagnosis;however,other studies such as breath tests,with a sensitivity of 89% and a specificity of 80%,or the endoscopic capsule contribute to the diagnosis.There is no cure;however,management must be multidisciplinary,focused on slowing the progression of diabetic gastroenteropathy,reducing symptoms,and restoring function;that includes nutritional recommendation,maintain glucose levels kept below 180 mg/dL,use of prokinetics,anti-emetics;nowadays,it has been special interest in surgical treatment,such as pyloroplasty,also gastric electrical stimulation appears to be another alternative.Marcio JoséConcepción Zavaleta Jhean Gabriel Gonzáles Yovera Diego Martín Moreno Marreros Luciana del Pilar Rafael Robles Kely Roxana Palomino Taype Karen Nohelly Soto Gálvez Luis Fernando Arriola Torres Julia Cristina Coronado Arroyo Luis Alberto Concepción Urteaga 2021World Journal of Diabetes2021,12,6:4
7Diagnosis and Treatment of Hepatocellular Carcinoma显示文摘Hashem B. El-Serag Jorge A. Marrero Lenhard Rudolph K. Rajender Reddy 2008Gastroenterology2008,,6:4
8Safety and efficacy of sorafenib for the treatment of recurrent hepatocellular carcinoma after liver transplantation显示文摘Abhijeet Waghray Bengi Balci Galal El‐Gazzaz Richard Kim Robert Pelley KV Narayanan Menon Bassam Estfan Carlos Romero‐Marrero Federico Aucejo 2013Clin Transplant2013,,4:3
9A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C显示文摘Chun-Tao Wai Joel K. Greenson Robert J. Fontana John D. Kalbfleisch Jorge A. Marrero Hari S. Conjeevaram Anna S.-F. Lok 2003Hepatology2003,,2:3
10α-Fetoprotein, Des-γ Carboxyprothrombin, and Lectin-Bound α-Fetoprotein in Early Hepatocellular Carcinoma显示文摘Jorge A. Marrero Ziding Feng Yinghui Wang Mindie H. Nguyen Alex S. Befeler Lewis R. Roberts K. Rajender Reddy Denise Harnois Josep M. Llovet Daniel Normolle Jackie Dalhgren David Chia Anna S. Lok Paul D. Wagner Sudhir Srivastava Myron Schwartz 2009Gastroenterology2009,,1:3
11Des-gamma carboxyprothrombin can differentiate hepatocellular carcinoma from nonmalignant chronic liver disease in american patients显示文摘Jorge A. Marrero Grace L. Su Wei Wei Dawn Emick Hari S. Conjeevaram Robert J. Fontana Anna S. Lok 2003Hepatology2003,,5:2
12NAFLD may be a common underlying liver disease in patients with hepatocellular carcinoma in the United States显示文摘Jorge A. Marrero Robert J. Fontana Grace L. Su Hari S. Conjeevaram Dawn M. Emick Anna S. Lok 2002Hepatology2002,,6:2
13Diagnosis and Treatment of Hepatocellular Carcinoma显示文摘Hashem B. El-Serag Jorge A. Marrero Lenhard Rudolph K. Rajender Reddy 2008Gastroenterology2008,,6:2
14Interleukin-6 and oncostatin M are elevated in liver disease inconjunction with candidate hepatocellular carcinoma biomarker GP73显示文摘Hongyan Liang Timothy M. Block Mengjun Wang Bradley Nefsky Ronald Long Julie Hafner Anand S. Mehta Jorge Marrero Robert Gish Pamela A. Norton 2012Cancer Biomarkers2012,,4:2
15Alcohol, tobacco and obesity are synergistic risk factors for hepatocellular carcinoma显示文摘Jorge A. Marrero Robert J. Fontana Sherry Fu Hari S. Conjeevaram Grace L. Su Anna S. Lok 2004Journal of Hepatology2004,,2:2
16Identification of osteopontin as a novel marker for early hepatocellular carcinoma显示文摘Sufen Shang Amelie Plymoth Shaokui Ge Ziding Feng Hugo R. Rosen Suleeporn Sangrajrang Pierre Hainaut Jorge A. Marrero Laura Beretta 2012Hepatology2012,,2:2
17Immunization program against influenza for adults 65 years or older at a community pharmacy in puerto rico 显示文摘MARRERO W HERNNDES L GARC A R 2006P R Health Sci J2006,25,1:1
18Effect of vitamin E and C dietary supplementation on some immune parameters of gilthead seabream (Sparus aurata)juveniles subjected to crowding stress显示文摘Montero D Marrero M Izquierdo M S 1999Aquac1999,171,:1
19Towards elimination of tuberculosis in a low income country:the experience of Cuba,1962-97显示文摘Marrero A Caminero JA Rodriguez R 2000Thorax2000,55,:1
20Fate of heavy metals and radioactive metals in gasification of sewage sludge 显示文摘Thomas W Marrero Brendan P 2004Waste Management2004,24,:1
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