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| 1 | Hepatocellular carcinoma: From diagnosis to treatment显示文摘Hepatocellular carcinoma(HCC) is the sixth most prevalent malignancy worldwide and is a rising cause of cancer related mortality. Risk factors for HCC are well documented and effective surveillance and early diagnosis allow for curative therapies. The majority of HCC appears to be caused by cirrhosis from chronic hepatitis B and hepatitis C virus. Preventive strategies include vaccination programs and anti-viral treatments.Surveillance with ultrasonography detects early stage disease and improves survival rates. Many treatment options exist for individuals with HCC and are determined by stage of presentation. Liver transplantation is offered to patients who are within the Milan criteria and are not candidates for hepatic resection. In patients with advanced stage disease, sorafenib shows some survival benefit. | Abhijeet Waghray Arvind R Murali KV Narayanan Menon | 2015 | World Journal of Hepatology2015，7，8： | 27 |
| 2 | Safety and efficacy of sorafenib for the treatment of recurrent hepatocellular carcinoma after liver transplantation显示文摘 | Abhijeet Waghray Bengi Balci Galal El‐Gazzaz Richard Kim Robert Pelley KV Narayanan Menon Bassam Estfan Carlos Romero‐Marrero Federico Aucejo | 2013 | Clin Transplant2013，，4： | 3 |
| 3 | Colorectal Glandular-Neuroendocrine Mixed Tumor: Pathologic Spectrum and Clinical Implications显示文摘 | Yunru Li Annie Yau David Schaeffer Anthony Magliocco Xianyong Gui Stefan Urbanski Ranjit Waghray David Owen Zu-hua Gao | 2011 | The American Journal of Surgical Pathology2011，，3： | 2 |
| 4 | Histamine 3 receptor activation mediates inhibition of acid secretion during Helicobacter-induced gastritis显示文摘AIM:To test the hypothesis that histamine 3 receptor (H3R)activation during Helicobacter infection inhibits gastric acid secretion in vivo and in vitro.METHODS:Helicobacter felis(H.felis)infected and uninfected C57Bl/6 mice were infused with either PBS or the H3 receptor antagonist thioperamide(THIO)for 12 wk.After treatment,mice were analyzed for morphological changes and gastric acid content.Total RNA was prepared from the stomachs of each group and analyzed for changes in somatostatin and gastrin mRNA abundance by real time-polymerase chain reaction(RTPCR).Location of H3 receptors in the stomach was analyzed by co-localization using antibodies specific for the H3 receptor and parietal cell marker H + ,K + -ATPase βsubunit. RESULTS:Inflammation and parietal cell atrophy was observed after 12 wk of H.felis infection.Interestingly, treatment with the H3R antagonist thioperamide(THIO) prior to and during infection prevented H.felis-induced inflammation and atrophy.Compared to the uninfected controls,infected mice also had significantly decreased gastric acid.After eradication of H.felis with THIO treatment,gastric acidity was restored.Compared to the control mice,somatostatin mRNA abundance was decreased while gastrin gene expression was elevated during infection.Despite elevated gastric acid levels, after eradication of H.felis with THIO,somatostatin mRNA was elevated whereas gastrin mRNA was suppressed.Immunofluorescence revealed the presence of H3 receptors on the parietal cells,somatostatin-secreting D-cells as well as the inflammatory cells. CONCLUSION:This study shows that during H.felis infection,gastric acidity is suppressed as a consequence of an inhibitory effect on the parietal cell by H3R activation.The stimulation of gastric mucosal H3Rs increases gastrin expression and release by inhibiting release of somatostatin. | Yana Zavros Nisreen Mesiwala Meghna Waghray Andrea Todisco Arthur Shulkes Juanita L Merchant | 2010 | World Journal of Gastrointestinal Pathophysiology2010，1，5： | 2 |
| 5 | Mediastinal mass in a 25-year-old man显示文摘 | Waghray A Sherpa L Carpio G | 2014 | Chest2014，146，2： | 1 |
| 6 | Prostate-specific antigen,a serine protease,facilitates human prostate cancer cell invasion显示文摘 | WEBBER M M WAGHRAY A BELLO D | 1995 | Clin Cancer Res1995，1，10： | 1 |
| 7 | Crystal Structure of the HCV IRES Central Domain Reveals Strategy for Start-Codon Positioning显示文摘 | Katherine E. Berry Shruti Waghray Stefanie A. Mortimer Yun Bai Jennifer A. Doudna | 2011 | Structure2011，，10： | 1 |
| 8 | Prostate-specific antigen, a serine protease, facilitates human prostate cancer cell invasion 显示文摘 | Webber MM Waghray A Bello D | 1995 | Clin Cancer Res1995，1，10： | 1 |
| 9 | Hydrogen peroxide is a diffusible paracrine signal for the induction of epithelial cell death by activated myofibroblasts显示文摘 | Waghray M Cui Z Horowitz JC | 2005 | FASEB J2005，19，7： | 1 |
| 10 | Increased expression of tissue-type transglutaminase following middle cerebral artery occlusion in rats显示文摘 | Tolentino PJ Waghray A Wang KK | 2004 | J Neurochem2004，89，5： | 1 |
| 11 | Identification of differentially expressed genes by serial analysis of gene expression in human prostate cancer显示文摘 | Waghray A Schober M Feroze F | 2001 | Cancer Res2001，15，： | 1 |
| 12 | The importonce of sampling site in the measurement of whole blood platelet flow cytometry显示文摘 | Rubens FD Labow RS Waghray G | | 0，，： | 1 |
| 13 | Synthesis of LiCoO2 powder for lithium ion batteries from precursors derived by rotary evaporation显示文摘 | Kumta P N Gallet D Waghray A | 1998 | J Power Sources1998，72，： | 1 |
| 14 | Street foods in Africa显示文摘 | Ramesh V Bhat Kavita Waghray | 2000 | World Rev Nutr Diet2000，，： | 1 |
| 15 | Interleukin-1 beta promotes gastric atrophy through suppression of sonic hedgehog显示文摘 | Waghray M Zavros Y Saqui-Salces M | 2010 | Gastrotenterology2010，138，2： | 1 |
| 16 | Activation of the pro-survival Pi3-k/Akt pathway by transforming growth factor-betal in mesenchymal cells is mediated by p38 MAPK-dependent induction of an autocrine growth factor 显示文摘 | Horowitz JC Lee DY Waghray M | 2004 | J Biol Chem2004，2799，： | 1 |
| 17 | Paracrine Hedgehog Signaling in Stomach and Intestine: New Roles for Hedgehog in Gastrointestinal Patterning显示文摘 | ?sa Kolterud Ann S. Grosse William J. Zacharias Katherine D. Walton Katherine E. Kretovich Blair B. Madison Meghna Waghray Jennifer E. Ferris Chunbo Hu Juanita L. Merchant Andrzej A. Dlugosz Andreas H. Kottmann Deborah L. Gumucio | 2009 | Gastroenterology2009，，2： | 1 |
| 18 | Reduced pepsin A processing of sonic hedgehog in parietal cells precedes gastric atrophy and transformation显示文摘 | Zavros Y Waghray M Tessier A | 2007 | J Biol Chem2007，282，33： | 1 |
| 19 | Synthesis of LiCoO2 powders for lithium-ion batteries from precursors derived by rotary evaporation显示文摘 | Kumta N P Gallet K Waghray A | 1998 | J Power Sources1998，72，： | 1 |
| 20 | Identification of differentiaUy expressed genes by serial analysis of gene expression in human prostate cancer显示文摘 | Waghray A Schober M Feroze F | 2001 | Cancer Res2001，61，10： | 1 |
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