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| 1 | 急性缺血性卒中的血管内治疗:神经介入外科学学会实践标准委员会的报告显示文摘目的总结采用血管内技术治疗急性缺血性卒中的有关证据并等级分类。方法对美国心脏协会(American Heart Association,AHA)以前发表的推荐意见进行审查并作为当前流程的基础。在此这基础上,进行系统的文献回顾以评估支持急性缺血性卒中血管内治疗的证据。根据AHA卒中委员会和牛津大学循证医学中心提出的循证医学证据分级指南进行评估。对操作安全性、技术效果以及对临床转归的影响进行特别审核。 | K A Blackham P M Meyers T A Abruzzo F C Alberquerque D Fiorella J Fraser D Frei C D Gandhi D V Heck J A Hirsch D P Hsu M Jayaraman S Narayanan C Prestigiacomo J L Sunshine 包元飞(译) 李永坤(译) 刘新峰(译) | 2012 | 国际脑血管病杂志2012，20，12： | 28 |
| 2 | Hepatocellular carcinoma: From diagnosis to treatment显示文摘Hepatocellular carcinoma(HCC) is the sixth most prevalent malignancy worldwide and is a rising cause of cancer related mortality. Risk factors for HCC are well documented and effective surveillance and early diagnosis allow for curative therapies. The majority of HCC appears to be caused by cirrhosis from chronic hepatitis B and hepatitis C virus. Preventive strategies include vaccination programs and anti-viral treatments.Surveillance with ultrasonography detects early stage disease and improves survival rates. Many treatment options exist for individuals with HCC and are determined by stage of presentation. Liver transplantation is offered to patients who are within the Milan criteria and are not candidates for hepatic resection. In patients with advanced stage disease, sorafenib shows some survival benefit. | Abhijeet Waghray Arvind R Murali KV Narayanan Menon | 2015 | World Journal of Hepatology2015，7，8： | 27 |
| 3 | 基于改进EEMD的穿墙雷达动目标微多普勒特性分析显示文摘穿墙雷达动目标探测中人的心跳、呼吸、手臂摆动等运动的微多普勒信号是非线性、非平稳信号,可以采用经验模式分解(EMD)对其进行时频分析。由于EMD分解存在模式混合问题,该文提出一种改进的整体平均经验模式分解(EEMD)方法,并将其应用于穿墙雷达人的运动微多普勒特性分析中,并且对分解后的每个本征模式函数(IMF)进行Hilbert-Huang变换(HHT),得到信号的时间-频率-能量谱。仿真数据和实验结果分析均表明,改进的EEMD方法不仅能够有效消除EMD中的模式混合问题,将人运动微多普勒信号中的不同频率尺度分解在不同的IMF中,而且还能够有效抑制原始信号中的噪声,提高信噪比,得到更精细、更清晰的时频分布。 | 王宏 Narayanan R M 周正欧 李廷军 孔令讲 | 2010 | 电子与信息学报2010，32，6： | 24 |
| 4 | Inverted internal limiting membrane flap technique for very large macular hole显示文摘AIM: To assess the anatomical and visual outcome of idiopathic macular holes greater than 1000 μm using the inverted internal limiting membrane flap technique.METHODS: This retrospective case series included 5 eyes of 5 patients with idiopathic macular hole with base diameter greater than 1000 μm who underwent inverted internal limiting membrane flap technique along with standard 23 G pars plans vitrectomy with posterior hyaloid detachment and fluid gas exchange with 12%-14% perfluoropropane(C3F8). Preoperative and postoperative visual acuity and spectral domain optical coherence tomography images were evaluated. The main outcome measures were visual outcome and macular hole closure.RESULTS: Mean age was 63.2±8.4y with all 5 subjects being females. Mean duration of symptoms was 11±14 mo with a mean postoperative follow up of 13.2 ±13 mo. The mean base diameter of the macular holes was 1420±84.8 μm(1280-1480 μm). Type 1 closure was achieved in four out of five patients, while one patient had type 2 closure using the inverted internal limiting membrane(ILM) flap technique. Median baseline BCVA was 0.79 log MAR(Snellen's equivalent 20/120) and median final BCVA0.6 log MAR(Snellen's equivalent 20/80) with mean visual improvement of approximately three lines improvement. No complications related to surgical procedure were noted.CONCLUSION: The inverted internal limiting membrane flap technique may be promising for very large macular holes with high rate of macular closure and good visual outcome. | Mitali Khodani Pooja Bansal Raja Narayanan Jay Chhablani | 2016 | International Journal of Ophthalmology(English edition)2016，9，8： | 11 |
| 5 | Machine-learned interatomic potentials by active learning:amorphous and liquid hafnium dioxide显示文摘We propose an active learning scheme for automatically sampling a minimum number of uncorrelated configurations for fitting the Gaussian Approximation Potential(GAP).Our active learning scheme consists of an unsupervised machine learning(ML)scheme coupled with a Bayesian optimization technique that evaluates the GAP model.We apply this scheme to a Hafnium dioxide(HfO2)dataset generated from a“melt-quench”ab initio molecular dynamics(AIMD)protocol.Our results show that the active learning scheme,with no prior knowledge of the dataset,is able to extract a configuration that reaches the required energy fit tolerance.Further,molecular dynamics(MD)simulations performed using this active learned GAP model on 6144 atom systems of amorphous and liquid state elucidate the structural properties of HfO2 with near ab initio precision and quench rates(i.e.,1.0 K/ps)not accessible via AIMD.The melt and amorphous X-ray structural factors generated from our simulation are in good agreement with experiment.In addition,the calculated diffusion constants are in good agreement with previous ab initio studies. | Ganesh Sivaraman Anand Narayanan Krishnamoorthy Matthias Baur Christian Holm Marius Stan Gábor Csányi Chris Benmore Álvaro Vázquez-Mayagoitia | 2020 | npj Computational Materials2020，，1： | 10 |
| 6 | What can imaging tell us about cognitive impairment and dementia?显示文摘Dementia is a contemporary global health issue with far reaching consequences, not only for affected individuals and their families, but for national and global socioeconomic conditions. The hallmark feature of dementia is that of irreversible cognitive decline, usually affecting memory, and impaired activities of daily living. Advances in healthcare worldwide have facilitated longer life spans, increasing the risks of developing cognitive decline and dementia in late life. Dementia remains a clinical diagnosis. The role of structural and molecular neuroimaging in patients with dementia is primarily supportive role rather than diagnostic, American and European guidelines recommending imaging to exclude treatable causes of dementia, such as tumor, hydrocephalus or intracranial haemorrhage, but also to distinguish between different dementia subtypes, the commonest of which is Alzheimer's disease. However, this depends on the availability of these imaging techniques at individual centres. Advanced magnetic resonance imaging(MRI) techniques, such as functional connectivity MRI, diffusion tensor imaging and magnetic resonance spectroscopy, and molecular imaging techniques, such as 18 F fluoro-deoxy glucose positron emission tomography(PET), amyloid PET, tau PET, are currently within the realm of dementia research but are available for clinical use. Increasingly the research focus is on earlier identification of at risk preclinical individuals, for example due to family history. Intervention at the preclinical stages before irreversible brain damage occurs is currently the best hope of reducing the impact of dementia. | Leela Narayanan Alison Dorothy Murray | 2016 | World Journal of Radiology2016，8，3： | 7 |
| 7 | Microstructure and texture evolution in AZ31 magnesium alloy during caliber rolling at different temperatures显示文摘Magnesium alloy AZ31 was caliber rolled at different temperatures viz.523K,573K,623K,673K and 723K imposing a total cumulative reduction of 92%and a cumulative strain of 2.6.The associated microstructure and texture evolution were studied using Electron Back Scattered Diffraction(EBSD)and X-ray macro-texture observations respectively.Grain refinement was observed in all the caliber rolled bars indicating the occurrence of dynamic recrystallization.Asymmetry parameter and texture index were used to study the evolution of texture.Near doubling of the yield strength at room temperature was observed by caliber rolling at a temperature of 573K.The improvement in mechanical properties was explained on the basis of the fine grain microstructures and suitable development of crystallographic texture.Based on the present study,warm caliber rolling can be used as a good production method for obtaining long bars of high strength magnesium alloy AZ31. | Abhishek Tripathi S.V.S.Narayana Murty P.Ramesh Narayanan | 2017 | Journal of Magnesium and Alloys2017，5，3： | 7 |
| 8 | Machine learning enabled autonomous microstructural characterization in 3D samples显示文摘We introduce an unsupervised machine learning(ML)based technique for the identification and characterization of microstructures in three-dimensional(3D)samples obtained from molecular dynamics simulations,particle tracking data,or experiments.Our technique combines topology classification,image processing,and clustering algorithms,and can handle a wide range of microstructure types including grains in polycrystalline materials,voids in porous systems,and structures from self/directed assembly in soft-matter complex solutions.Our technique does not require a priori microstructure description of the target system and is insensitive to disorder such as extended defects in polycrystals arising from line and plane defects.We demonstrate quantitively that our technique provides unbiased microstructural information such as precise quantification of grains and their size distributions in 3D polycrystalline samples,characterizes features such as voids and porosity in 3D polymeric samples and micellar size distribution in 3D complex fluids.To demonstrate the efficacy of our ML approach,we benchmark it against a diverse set of synthetic data samples representing nanocrystalline metals,polymers and complex fluids as well as experimentally published characterization data.Our technique is computationally efficient and provides a way to quickly identify,track,and quantify complex microstructural features that impact the observed material behavior. | Henry Chan Mathew Cherukara Troy D.Loeffler Badri Narayanan Subramanian K.R.S.Sankaranarayanan | 2020 | npj Computational Materials2020，，1： | 5 |
| 9 | Metallurgical analysis of a failed maraging steel shear screw used in the band separation system of a satellite launch vehicle显示文摘Maraging steels have excellent combination of strength and toughness and are extensively used for a variety of aerospace applications. In one such critical application, this steel was used to fabricate shear screws of a stage separation system in a satellite launch vehicle. During assembly preparations, one of the shear screws which connected the separation band and band end block has failed at the first thread. Microstructural analysis revealed that the crack originated from the root of the thread and propagated in an intergranular mode. The failure is attributed to combined effect of stress and corrosion leading to stress corrosion cracking. | S.V.S. Narayana MURTY Sushant K. MANWATKAR E Ramesh NARAYANAN | 2016 | Defence Technology(防务技术)2016，12，5： | 5 |
| 10 | Ivabradine in the treatment of systolic heart failure- A systematic review and meta-analysis显示文摘AIM To perform a systematic-review and meta-analysis to compare outcomes of ivabradine combined with betablocker to beta-blocker alone in heart failure with reduced ejection fraction(HFr EF).METHODS We searched PubM ed, Cochrane, EMBASE, CINAHL and Web of Science for trials comparing ivabradine + betablocker to beta-blocker alone in HFr EF. We performed a systematic-review and meta-analysis of published literature. Primary end-point was combined end point of cardiac death and hospitalization for heart failure.RESULTS Six studies with 17671 patients were included. Mean follow-up was 8.7 ± 7.9 mo. Combined end-point of heart failure readmission and cardiovascular death was better in ivabradine + beta-blocker group compared to beta-blocker alone(RR: 0.93, 95%CI: 0.79-1.09, P = 0.354). Mean difference(MD) in heart rate was higher in the ivabradine + beta-blocker group(MD: 6.14, 95%CI: 3.80-8.48, P < 0.001). There was no difference in all cause mortality(RR: 0.98, 95%CI: 0.89-1.07, P = 0.609), cardiovascular mortality(RR: 0.99, 95%CI: 0.86-1.15, P = 0.908) or heart failure hospitalization(RR: 0.87, 95%CI: 0.68-1.11, P = 0.271). CONCLUSION From the available clinical trials, ivabradine + betablocker resulted in a significantly greater reduction in HRcoupled with improvement in combined end-point of heart failure readmission and cardiovascular death but with no improvement in all cause or cardiovascular mortality. Given the limited evidence, further randomized controlled trials are essential before widespread clinical application of ivabradine + beta-blocker is advocated for HFrEF. | Mahesh Anantha Narayanan Yogesh NV Reddy Janani Baskaran Abhishek Deshmukh David G Benditt Ganesh Raveendran | 2017 | World Journal of Cardiology2017，9，2： | 5 |
| 11 | Nonylphenol in bivalves and sediments in the northeast coast of China显示文摘To understand nonylphenol (NP) contamination in the northeast coastal environment in China, NP was determined in 19 sediment and 20 bivalve samples collected during November 2005. NP was identified in all sediment samples in the range of 8.8 to 1.0 × 10 3 ng/g dw (dry weight), with an average of 0.12 × 10 3 ng/g dw. Most of the bivalve samples (oysters and mussels) contained detectable amounts of NP that ranged from ND (not detected) to 7.6 × 10 3 ng/g dw, with an average value of 0.79 × 10 3 ng/g dw. These results indicated that NP is ubiquitous in sediments and bivalves from the northeast coast of China, and are even present in bivalves sold as seafood. Serious contamination with NP was recorded off the coast of Bohai Strait and in semi-enclosed coastal environment such as Jiaozhou Bay and Liaodong Bay. Possible environmental and human health implications were understood in this study. | Juan Wang Won-joon Shim Un-hynk Yim Narayanan Kannan Donghao Li | 2010 | Journal of Environmental Sciences2010，22，11： | 4 |
| 12 | 结核病的性别差异:南印度某农村地区DOTS项目报告显示文摘背景:南印度 Tiruvallur 地区。目的:了解 14 岁以上成年人在结核感染和患病、就医途径、就医行为、诊断延误、接受 DOT的方便程度、疾病歧视以及治疗依从性等方面的性别差异。方法:相关数据主要来自:1)社区调查,2)在公立初级保健卫生机构(PHIS)主动就医的病人,3)转诊到 PHIS 进行痰涂片检查的可疑结核病人;4)DOTS 策略下的登记报告结核病人。并将社区调查结果与 PHIS 登记病人进行比较。结果:社区人群中 66%的男性和 57%的女性感染了结核菌;男性和女性的涂阳肺结核患病率分别为568/10 万和87/10 万。在 PHIS 就医的男性少于女性,男女之比为 68:100。女性占社区调查发现涂阳病人的 13%;占 PHIS 发现病人的 20%(P<0.05)。随着年龄的增长,男性和女性的登记率显著降低。女性感觉难于与家人讨论自己病情的比例要高于男性(21%∶14%),也更需要有人陪伴去接受 DOT(11%∶6%)。男性的治疗中断率比女性高 1 倍(19%∶8%;P<0.01)。结论:尽管女性发病后更容易遭受歧视和不便,但女性更易于利用医疗服务、接受 DOTS 策略登记以及依从治疗。而男性以及高龄病人在诊断和 DOT服务方面更需要帮助。 | R. Balasubramanian R. Garg T. Santha P. G. Gopi R. Subramani V. Chandrasekaran A. Thomas R. Rajeswari S. Anandakrishnan M. Perumal C. Niruparani G. Sudha K. Jaggarajamma T. R. Frieden P. R. Narayanan 刘小秋 | 2004 | 结核与肺部疾病杂志2004，7，4： | 4 |
| 13 | 动脉瘤性蛛网膜下腔出血患者出血后脑血管痉挛的介入治疗显示文摘本临床实践标准述及动脉瘤性蛛网膜下腔出血患者出血后脑血管痉挛(post—hemorrhagiccerebralvasospasm,PHCV)的介入治疗。这些结论基于神经介入外科学学会的标准委员会的评估,包括使用由美国心脏协会卒中委员会和牛津大学循证医学中心提出的循证医学指南进行的文献回顾。特别关注现有介入治疗方法的安全性和有效性,包括腔内球囊血管成形术(transluminalballoonangioplasty,TBA)和动脉内血管扩张药物输注治疗(intra-arterialvasodilatorinfusiontherapy,IAVT)。评估结果显示,这些侵袭性介入治疗可能有益,并可考虑用于PHCV,如伴有脑缺血症状和最佳的药物治疗无效的患者的治疗。概括起来,IAVT对累及近端和(或)远端颅内脑循环的PHCV可能有益,而TBA则可能对累及近端颅内脑循环的PHCV有益。评估结果显示,对于上述适应证,根据美国心脏协会指南可将TBA和IAVT归为IIb级推荐和B级证据,根据牛津大学循证医学中心指南则可归为4级推荐和C级证据。 | Todd Abruzzo Christopher Moran Kristine A Blacldaam Clifford J Eskey Raisa Lev Philip Meyers Sandra Narayanan Charles Joseph Prestigjacol~ 黄凯滨(译) 吴永明(译) | 2013 | 国际脑血管病杂志2013，21，1： | 4 |
| 14 | Chemopreventive effect of apple and berry fruits against colon cancer显示文摘Colon cancer arises due to the conversion of precancerous polyps(benign)found in the inner lining of the colon.Prevention is better than cure,and this is very true with respect to colon cancer.Various epidemiologic studies have linked colorectal cancer with food intake.Apple and berry juices are widely consumed among various ethnicities because of their nutritious values.In this review article,chemopreventive effects of these fruit juices against colon cancer are discussed.Studies dealing with bioavailability,in vitro and in vivo effects of apple and berry juices are emphasized in this article.A thorough literature survey indicated that various phenolic phytochemicals present in these fruit juices have the innate potential to inhibit colon cancer cell lines.This review proposes the need for more preclinical evidence for the effects of fruit juices against different colon cancer cells,and also strives to facilitate clinical studies using these juices in humans in large trials.The conclusion of the review is that these apple and berry juices will be possible candidates in the campaign against colon cancer. | Saravana Kumar Jaganathan Muthu Vignesh Vellayappan Gayathri Narasimhan Eko Supriyanto Dyah Ekashanti Octorina Dewi Aqilah Leela T Narayanan Arunpandian Balaji Aruna Priyadarshini Subramanian Mustafa Yusof | 2014 | World Journal of Gastroenterology2014，20，45： | 3 |
| 15 | Safety and efficacy of sorafenib for the treatment of recurrent hepatocellular carcinoma after liver transplantation显示文摘 | Abhijeet Waghray Bengi Balci Galal El‐Gazzaz Richard Kim Robert Pelley KV Narayanan Menon Bassam Estfan Carlos Romero‐Marrero Federico Aucejo | 2013 | Clin Transplant2013，，4： | 3 |
| 16 | Comparative Analysis of the Safety and Efficacy of Transcatheter Arterial Chemoembolization and Yttrium-90 Radioembolization in Patients with Unresectable Hepatocellular Carcinoma显示文摘 | Craig Lance Gordon McLennan Nancy Obuchowski Grace Cheah Abraham Levitin Mark Sands James Spain Shyam Srinivas Sankaran Shrikanthan Federico N. Aucejo Richard Kim K.V. Narayanan Menon | 2011 | Journal of Vascular and Interventional Radiology2011，，12： | 3 |
| 17 | Effect of Polymer Inclusion in Preparation of Thick LZO Buffer Layers for YBCO Coated Conductors显示文摘In this work,water-based precursor solutions suitable for dip-coating of thick La_2Zr_2O_7(LZO) buffer layers for coated conductors on Ni-5%W substrates with an inclusion of polymeric polyvinyl pyrrolidone were developed.The effect of varying percentage of the polymer addition on the preparation of the deposited films with maximum crack-free thickness was investigated.This novel water-based chemical solution deposition method involving polymers in two different chelate-chemistry compositions revealed the possibility to grow single,crack-free layers with thicknesses ranging from 140 to 280 nm,with good crystallinity and epitaxial growth.The effect of increasing polymer concentrations on the morphology and the structure of the films was studied.The appropriate buffer layer action of the films in preventing Ni diffusion was studied by X-ray photoelectron spectroscopy. | Vyshnavi Narayanan Isabel Van Driessche | 2013 | Journal of Materials Science & Technology2013，29，3： | 3 |
| 18 | Effect of surface mechanical attrition treatment of titanium using alumina balls: surface roughness, contact angle and apatite forming ability显示文摘 | M. JAMESH T. S. N. SANKARA NARAYANAN Paul K. CHU II Song PARK Min Ho LEE | 2013 | Frontiers of Materials Science2013，7，3： | 3 |
| 19 | Phoenix phylogeny, and analysis of genetic variation in a diverse collection of date palm(Phoenix dactylifera) and related species显示文摘Date palm(Phoenix dactylifera),one of the most ancient crops,is grown commercially in>30 countries.Using whole plastome assemblies,phylogenetic analyses revealed that cultivated date palm accessions share the same clade with Phoenix sylvestris,Phoenix pusilla and Phoenix acaulis,which are native to the Indian subcontinent,and Phoenix caespitosa that is native to the Arabian Peninsula and the deserts of Somalia.Analysis of genetic diversity and genetic relationships among date palm accessions from 13 producing countries involved 195 date palm accessions that were genotyped at 19 microsatellite loci.Extensive genetic diversity was observed,with many accessions heterozygous for most markers in this clonally propagated crop.The average number of alleles per locus(42.1),expected heterozygosity(0.8),observed heterozygosity(0.47)and fixation indices(FST=0.42)demonstrated substantial genetic diversity and population structure.Iraqi accessions were found to have the richest allelic diversity,and the most private alleles.The model-based Bayesian method indicated that these accessions could be broadly divided into two structure groups,one group with predominantly African accessions and another predominantly Asian.Some germplasm,especially from Tunisia and Iraq,deviated from this generalization.Many accessions in the STRUCTURE-derived groups were found to be genetic admixtures,with gene flow between Asian and African groups.Indian and Pakistani date palms were found to be most closely related to North African germplasm. | Srinivasa R.Chaluvadi Porter Young Kentrez Thompson Bochra Amina Bahri Bhavesh Gajera Subhash Narayanan Robert Krueger Jeffrey L.Bennetzen | 2019 | Plant Diversity2019，41，5： | 3 |
| 20 | Influence of counterbody material on fretting wear behaviour of surface mechanical attrition treated Ti–6Al–4V显示文摘 | S. Anand Kumar S. Ganesh Sundara Raman T.S.N. Sankara Narayanan R. Gnanamoorthy | 2013 | Tribology International2013，，： | 2 |
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