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| 1 | Video-Assisted Thoracoscopic Surgery (VATS) for Patients with Solitary Fibrous Tumors of the Pleura显示文摘 | Jun Liu Chengjie Cai Daoyuan Wang Hanzhang Chen Linling Cheng Wenlong Shao Shuben Li Yubao Guan Yingying Gu Jianxing He | 2010 | Journal of Thoracic Oncology2010，，2： | 2 |
| 2 | Differential effects of donor and recipient IL28B and DDX58 SNPs on severity of HCV after liver transplantation显示文摘 | Scott W. Biggins James Trotter Jane Gralla James R. Burton Kiran M. Bambha Jennifer Dodge Megan Brocato Linling Cheng Matt McQueen Lisa Forman Michael Chang Igal Kam Gregory Everson Richard A. Spritz Goran Klintmalm Hugo R. Rosen | 2013 | Journal of Hepatology2013，，5： | 2 |
| 3 | An R2R3-MYB transcription factor as a negative regulator of the flavonoid biosynthesis pathway in Ginkgo biloba显示文摘 | Feng Xu Yingjing Ning Weiwei Zhang Yongling Liao Linling Li Hua Cheng Shuiyuan Cheng | 2014 | Functional & Integrative Genomics2014，，1： | 1 |
| 4 | Expression patterns of an isoflavone reductase-like gene and its possible roles in secondary metabolism in Ginkgo biloba显示文摘 | Cheng Hua Li Linling Xu Feng Wang Yan Yuan Honghui Wu Conghua Wang Shaobing Liao Zhiqin Hua Juan Wang Yuping Cheng Shuiyuan Cao Fuliang | 2013 | Plant Cell Reports2013，，5： | 1 |
| 5 | An R2R3-MYB transcription factor as a negative regulator of the flavonoid biosynthesis pathway in Ginkgo biloba显示文摘 | Feng Xu Yingjing Ning Weiwei Zhang Yongling Liao Linling Li Hua Cheng Shuiyuan Cheng | 2014 | Functional & Integrative Genomics2014，，1： | 1 |
| 6 | Increased natural killer cell cytotoxicity and NKp30 expression protects against hepatitis C virus infection in high‐risk individuals and inhibits replication in vitro显示文摘 | Lucy Golden‐Mason Andrea L. Cox Jessica A. Randall Linling Cheng Hugo R. Rosen | 2010 | Hepatology2010，，5： | 1 |
| 7 | Characteristics of alveolar macrophages in bronchioalveolar lavage fluids from active tuberculosis patients identified by single-cell RNA sequencing显示文摘Tuberculosis(TB),is an infectious disease caused by Mycobacterium tuberculosis(M.tuberculosis),and presents with high morbidity and mortality.Alveolar macrophages play an important role in TB pathogenesis although there is heterogeneity and functional plasticity.This study aimed to show the characteristics of alveolar macrophages from bronchioalveolar lavage fluid(BALF)in active TB patients.Single-cell RNA sequencing(scRNA-seq)was performed on BALF cells from three patients with active TB and additional scRNA-seq data from three healthy adults were established as controls.Transcriptional profiles were analyzed and compared by differential gene expression and functional enrichment analysis.We applied pseudo-temporal trajectory analysis to investigate correlations and heterogeneity within alveolar macrophage subclusters.Alveolar macrophages from active TB patients at the single-cell resolution are described.We found that TB patients have higher cellular percentages in five macrophage subclusters.Alveolar macrophage subclusters with increased percentages were involved in inflammatory signaling pathways as well as the basic macrophage functions.The TB-increased alveolar macrophage subclusters might be derived from M1-like polarization state,before switching to an M2-like polarization state with the development of M.tuberculosis infection.Cell-cell communications of alveolar macrophages also increased and enhanced in active TB patients.Overall,our study demonstrated the characteristics of alveolar macrophages from BALF in active TB patients by using scRNA-seq. | Qianqian Chen Chunmei Hu Wei Lu Tianxing Hang Yan Shao Cheng Chen Yanli Wang Nan Li Linling Jin Wei Wu Hong Wang Xiaoning Zeng Weiping Xie | 2022 | The Journal of Biomedical Research2022，36，3： | 1 |
| 8 | Hallmark guided identification and characterization of a novel immune-relevant signature for prognostication of recurrence in stageⅠ-Ⅲlung adenocarcinoma显示文摘The high risk of postoperative mortality in lung adenocarcinoma(LUAD)patients is principally driven by cancer recurrence and low response rates to adjuvant treatment.Here,A combined cohort containing 1,026 stageⅠ-Ⅲpatients was divided into the learning(n Z 678)and validation datasets(n Z 348).The former was used to establish a 16-mRNA risk signature for recurrence prediction with multiple statistical algorithms,which was verified in the valida-tion set.Univariate and multivariate analyses confirmed it as an independent indicator for both recurrence-free survival(RFS)and overall survival(OS).Distinct molecular characteristics between the two groups including genomic alterations,and hallmark pathways were compre-hensively analyzed.Remarkably,the classifier was tightly linked to immune infiltrations,high-lighting the critical role of immune surveillance in prolonging survival for LUAD.Moreover,the classifier was a valuable predictor for therapeutic responses in patients,and the low-risk group was more likely to yield clinical benefits from immunotherapy.A transcription factor regulato-ry proteineprotein interaction network(TF-PPI-network)was constructed via weighted gene co-expression network analysis(WGCNA)concerning the hub genes of the signature.The con-structed multidimensional nomogram dramatically increased the predictive accuracy.There-fore,our signature provides a forceful basis for individualized LUAD management with promising potential implications. | Yongqiang Zhang Zhao Yang Yuqin Tang Chengbin Guo Danni Lin d Linling Cheng Xun Hu Kang Zhang Gen Li | 2023 | Genes & Diseases2023，10，4： | 0 |
| 9 | Effect of Several Common Processing Methods on Content Changes of Resistant Starch and Main Nutrients in ‘Luotian Chestnut’显示文摘Using‘Luotian chestnut'as the raw material,the content changes of resistant starch and main nutrients in the processed fruit were studied after taken common processing of high-temperature steaming of canned food,sand-mixed frying and cooking without shells,with the aim to find out the effects of different processing methods on the content changes of nutrients in chestnuts. The result showed that there were significant differences in the resistant starch contents by different processing methods. After processing,the retention degree of resistant starch was the lowest using the methods of sand-mixed frying,of 42. 42%,while the highest was found in canned chestnut products,of 93. 16%. Among the main nutrients,adding water and sugar would reduce content of resistant starch,while increasing the protein content would promote the retention of resistant starch retention. The changes in lipid content had no effect or not a single promoting or weakening effects on the content of resistant starch. | Linling LI Bingjie HUANG Hua CHENG Xuehua ZHANG Xiaoling CHEN Shuiyuan CHENG | 2018 | Agricultural Biotechnology2018，7，5： | 0 |
| 10 | Embryoid Induction and Cell Suspension Culture of Premna microphylla Turca显示文摘In order to find suspension culture conditions suitable for Premna microphylla Turca,with the leaves of experimented P. microphylla as a material,embryogenic callus induction,subculture,dispersion of embryogenic callus and suspension culture were performed. The results showed that the calli induced from leaves were different. The medium most suitable for induction of loose embryogenic callus for suspension culture was MS + 0. 4 mg/L 2,4-D + 0. 4 mg/L NAA + 3% sucrose + 0. 8% agar. A better cell line could be obtained with cellulase and pectinase for dispersion of P. microphylla callus. The medium most suitable for suspension culture was MS + 0. 4 mg/L 2,4-D + 0. 8 mg/L KT + 3% sucrose. In this medium,the fresh weight of the suspension-cultured cells increased by 6. 46 times per 7 d. Dark culture was more suitable for cell proliferation. The average contents of pectin and protein were,respectively,6. 57% and 0. 12% in the suspended cells of P. microphylla,which had been cultured for 3 weeks under the optimum culture conditions. | Hua CHENG Zhichao LI Linling LI Shuiyuan CHENG | 2017 | Agricultural Biotechnology2017，6，3： | 0 |
| 11 | Isolation and Identification of Pathogenic Fungi Causing Decayin Luotian Chestnut during Late Storage Period and Research on Pathogenicity显示文摘In order to explore moldy mechanism of chestnut from Luotian County in storage process,the strains of pathogenic fungi were isolated from chestnuts after storage at room temperature for 70d.Six genera of fungi were found in chestnut through experimental identification,which were Ozoniumsp.,Fusarium sp.,Aspergillus sp.,Penicilliumsp.,Rhiopus sp.and Stachybotrys sp.,respectively.The re-inoculation tests had been conducted on pathogenic fungi whose isolating rate was greater than 10%.The result showed that the rest genera of fungi generally had no pathogenicity except Penicilliumsp.could infect non-injured chestnut with a lower moldy rate and lighter symptoms;but the moldy rate of strains was above 60% in injured inoculation and they showed heavy symptoms,among which the moldy rate of Ozoniumsp.and Aspergillus sp.were higher than 80%.The experimental results showed that injured chestnut were more likely to decay.Ozoniumsp.and Aspergillus sp.were important pathogenic fungi causing decay during storage process of chestnut. | Li Linling Li Zheng Hua Juan Cheng Hua Liao Zhiqin Cheng Shuiyuan Tang Qing | 2013 | Plant Diseases and Pests2013，4，6： | 0 |
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