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| 1 | Synergistic effects of non-thermal plasma-assisted catalyst and ultrasound on toluene removal显示文摘A wire-mesh catalyst coated by La0.8Sr0.2MnO3 was combined with a dielectric barrier discharge (DBD) reactor for toluene removal at atmospheric pressure. It was found that toluene removal efficiency and carbon dioxide selectivity were enhanced in the catalytic packed-bed reactor. In addition, ozone and nitrogen monoxide from the gas effluent byproducts decreased. This is the first time that ultrasound combined with plasma has been used for toluene removal. A synergistic effect on toluene removal was observed in the plasma-assisted ultrasound system. At the same time, the system increased toluene conversion and reduced ozone emission. | Yongli Sun Libo Zhou Luhong Zhang Hong Sui | 2012 | Journal of Environmental Sciences2012，24，5： | 9 |
| 2 | Actively priming autophagic cell death with novel transferrin receptor-targeted nanomedicine for synergistic chemotherapy against breast cancer显示文摘Recently, considerable attention in the field of cancer therapy has been focused on the mammalian rapamycin target(m TOR), inhibition of which could result in autophagic cell death(ACD). Though novel combination chemotherapy of autophagy inducers with chemotherapeutic agents is extensively investigated, nanomedicine-based combination therapy for ACD remains in infancy. In attempt to actively trigger ACD for synergistic chemotherapy, here we incorporated autophagy inducer rapamycin(RAP) into 7 pep-modified PEG-DSPE polymer micelles(7 pep-M-RAP) to specifically target and efficiently priming ACD of MCF-7 human breast cancer cells with high expression of transferrin receptor(Tf R). Cytotoxic paclitaxel(PTX)-loaded micelle(7 pep-M-PTX) was regarded as chemotherapeutic drug model. We discovered that with superior intracellular uptake in vitro and more tumor accumulation of micelles in vivo, 7 pep-M-RAP exhibited excellent autophagy induction and synergistic antitumor efficacy with 7 pep-M-PTX. Mechanism study further revealed that 7 pep-M-RAP and 7 pep-MPTX used in combination provided enhanced efficacy through induction of both apoptosis-and mitochondria-associated autophagic cell death. Together, our findings suggested that the targeted excess autophagy may provide a rational strategy to improve therapeutic outcome of breast cancer, and simultaneous induction of ACD and apoptosis may be a promising anticancer modality. | Dong Mei Binlong Chen Bing He Haibin Liu Zhiqiang Lin Jialiang Lin Xiaoyan Zhang Ning Sun Libo Zhao Xiaoling Wang Qiang Zhang | 2019 | Acta Pharmaceutica Sinica B2019，9，5： | 8 |
| 3 | Corrosion behavior of Ti_(3)AlC_(2) in molten KOH at 700℃显示文摘This paper investigated the corrosion behaviors of Ti_(3)AlC_(2) at 700℃in molten KOH with various mass ratios.If the mass ratio of KOH:Ti_(3)AlC_(2)≤2,Ti_(3)AlC_(2) can resist KOH hot corrosion in 2 h.Ti_(3)AlC_(2) suffered serious corrosion attack if the mass ratio≥3.The main compositions of corroded samples were amorphous graphite and potassium titanates(K_(2)O·nTiO_(2)).If the samples were washed by acid and dried,potassium titanates could decompose to K_(2)O and amorphous rutile.Based on the experimental results,a corrosion mechanism of Ti_(3)AlC_(2) in molten KOH was proposed. | Dandan SUN Aiguo ZHOU Zhengyang LI Libo WANG | 2013 | Journal of Advanced Ceramics2013，2，4： | 5 |
| 4 | Rare-earth element geochemistry reveals the provenance of sediments on the southwestern margin of the Challenger Deep显示文摘The hadal zone represents one of the last great frontiers in modern marine science,and deciphering the provenance of sediment that is supplied to these trench settings remains a largely unanswered question.Here,we examine the mineralogical and geochemical composition of a sediment core(core CD-1)that was recovered from the southwestern margin of the Challenger Deep within the Mariana Trench.Major element abundances and rare-earth element patterns from these sediments require inputs from both terrigenous dust and locally sourced volcanic debris.We exploit a two-endmember mixing model to demonstrate that locally sourced volcanic material dominates the sediment supply to the Challenger Deep(averaging^72%).The remainder,however,is supplied by aeolian dust(averaging^28%),which is consistent with adjacent studies that utilized Sr-Nd isotopic data.Building on a growing database,we strengthen our understanding of Asian aeolian dust input into the northwestern Pacific,which ultimately improves our appreciation of sedimentation in,and around,the hadal zone. | JIANG Zuzhou SUN Zhilei LIU Zhaoqing CAO Hong GENG Wei XU Haixia WANG Lisheng WANG Libo | 2019 | Journal of Oceanology and Limnology2019，37，3： | 5 |
| 5 | Optimizing interfacial electronic coupling with metal oxide to activate inert polyaniline for superior electrocatalytic hydrogen generation显示文摘Tuning and optimization of electronic structures and related reaction energetics are critical toward the rational design of efficient electrocatalysts.Herein,experimental and theoretical calculation demonstrate the originally inert N site within polyaniline(PANI)can be activated for hydrogen evolution by proper d-πinterfacial electronic coupling with metal oxide.As a result,the assynthesized WO3 assemblies@PANI via a facile redox-induced assembly and in situ polymerization,exhibits the electrocatalytic production of hydrogen better than other control samples including W18O49@PANI and most of the reported nobel-metal-free electrocatalysts,with low overpotential of 74 mV at 10 mA·cm−2 and small Tafel slope of 46 mV·dec−1 in 0.5M H2SO4(comparable to commercial Pt/C).The general efficacy of this methodology is also validated by extension to other metal oxides such as MoO3 with similar improvements. | Zhen-Feng Huang Jiajia Song Yonghua Du Shuo Dou Libo Sun Wei Chen Kaidi Yuan Zhengfei Dai Xin Wang | 2019 | Carbon Energy2019，1，1： | 5 |
| 6 | Overexpression of GhPFN2 enhances protection against Verticillium dahliae invasion in cotton显示文摘Growing evidence indicates that actin cytoskeleton is involved in plant innate immune responses,but the functional mechanism remains largely unknown.Here,we investigated the behavior of a cotton profilin gene(GhPFN2) in response to Verticillium dahliae invasion,and evaluated its contribution to plant defense against this soil-borne fungal pathogen.GhPFN2 expression was up-regulated when cotton root was inoculated with V.dahliae,and the actin architecture was reorganized in the infected root cells,with a clear increase in the density of filamentous actin and the extent of actin bundling.Compared to the wild type,GhPFN2-overexpressing cotton plants showed enhanced protection against V.dahliae infection and the actin cytoskeleton organization in root epidermal cells was clearly altered,which phenocopied that of the wild-type(WT) root cells challenged with V.dahliae.These results provide a solid line of evidence showing that actin cytoskeleton reorganization involving GhPFN2 is important for defense against V.dahliae infection. | Wenyan Wang Yongduo Sun Libo Han Lei Su Ouixian Xia Haiyun Wang | 2017 | Science China(Life Sciences)2017，60，8： | 4 |
| 7 | Embedded whispering-gallery mode microsphere resonator in a tapered hollow annular core fiber显示文摘We propose and demonstrate a tapered hollow annular core fiber (HACF) coupler for excitation of whisperinggallery modes (WGMs) of an embedded microsphere resonator. The coupler is simply fabricated by fusion splicing of a segment of HACF with the single-mode fiber (SMF), and then improved by tapering the splicing joint to reduce the cone-apex angle. Therefore, the coupling efficiency from the SMF to the HACF is enhanced to excite various WGMs via evanescent field coupling. Normal positive, negative symmetrical Lorentzian and asymmetric Fano line shapes can be obtained by varying the resonator size and location. Another interesting phenomenon is observed that a higher Q-factor mode in a lower Q-factor mode has a contrast as high as 58. Temperature sensing with good stability is also demonstrated. This embedded WGM microsphere resonator in the tapered HACF is expected to promote environmental adaptability in practical applications due to its simplicity and | JIAWEI WANG XIAOBEI ZHANG MING YAN LEI YANG FENGYU HOU WEN SUN XIAOTONG ZHANG LIBO YUAN HAI XIAO TINGYUN WANG | 2018 | Photonics Research2018，6，12： | 4 |
| 8 | Super-resolution imaging and tracking of TGF-β receptor II on living cells显示文摘Single-particle tracking photoactivated localization microscopy(spt PALM) has recently emerged as a powerful tool for high-density imaging and tracking of individual molecules in living cells. In this work, we have monitored and compared the diffusion dynamics of TGF-b type II receptor(Tb RII) at high expression level using both traditional single-particle tracking(SPT) and spt PALM.The ligand-induced aggregation of Tb RII oligomers was further indicated by spt PALM. Due to the capacity of distinguishing and tracking single molecules within diffraction limit, spt PALM outperforms traditional SPT by providing more accurate biophysical information. | Zi Ye Nan Li Libo Zhao Yahong Sun Hefei Ruan Mingliang Zhang Jinghe Yuan Xiaohong Fang | 2016 | Science Bulletin2016，61，8： | 3 |
| 9 | System architecture for high-performance permissioned blockchains显示文摘Blockchain(BC),as an emerging distributed database technology with advanced security and reliability,has attracted much attention from experts who devoted to efinance,intellectual property protection,the internet of things(IoT)and so forth.However,the inefficient transaction processing speed,which hinders the BC’s widespread,has not been well tackled yet.In this paper,we propose a novel architecture,called Dual-Channel Parallel Broadcast model(DCPB),which could address such a problem to a greater extent by using three methods which are dual communication channels,parallel pipeline processing and block broadcast strategy.In the dual-channel model,one channel processes transactions,and the other engages in the execution of BFT.The parallel pipeline processing allows the system to operate asynchronously.The block generation strategy improves the efficiency and speed of processing.Extensive experiments have been applied to BeihangChain,a simplified prototype for BC system,illustrates that its transaction processing speed could be improved to 16K transaction per second which could well support many real-world scenarios such as BC-based energy trading system and Micro-film copyright trading system in CCTV. | Libo FENG Hui ZHANG Wei-Tek TSAI Simeng SUN | 2019 | Frontiers of Computer Science2019，13，6： | 2 |
| 10 | In situ atomic-scale observation of dislocation behaviors in twin-structured Pt nanocrystals显示文摘The deformation mechanisms of twin-structured metallic materials have attracted great interest.Though previous theoretical predictions have suggested that the repulsive force of the twin boundary(TB)can significantly affect the deformation of twinstructured metals,it remains unclear whether this prediction applies to experimental conditions.In this paper,the atomic-scaled deformation process of twin-structured Pt nanocrystals was in situ observed using our home-made device in a high-resolution transmission electron microscope.We have shown that the plastic deformation of the twin-structured Pt nanocrystals was governed by full dislocation generation as well as Lomer dislocation(LD)lock formation and destruction.After LD locks were destructed,these full dislocations tended to move towards the surface of the nanocrystals.The findings revealed that due to the ultra-high repulsive force of TB on dislocation,there was no dislocation-TB reaction during the deformation.These findings can enrich our understanding of the dislocation behaviors of twin-structured nanocrystals. | GUO YiZhong SUN Tao FU LiBo HAO LongHu HUANG Ming WEI RuJian LUO JunFeng HE Xin WANG XingQuan XIONG XiaoDong WANG LiHua HAN XiaoDong | 2021 | Science China(Technological Sciences)2021，64，3： | 2 |
| 11 | Enhancing stability by tuning element ratio in 2D transition metal chalcogenides显示文摘Two-dimensional(2D)transition metal chalcogenides(TMCs)are known to be susceptible to the atmosphere,which greatly obscures the intrinsic physical and chemical properties.The quantitative origin of the instability on the atomic scale has not been well investigated due to the lack of environmentally stable TMCs sample.Here,we find the stability of the grown TMCs is strongly relevant to their initial element ratios,and thus the stoichiometric bonded TMCs have favorable stability,benefitted from the TMCs with controllable chalcogenisation.In this study,the degree of structural degradation has been quantitatively defined by the reduced element ratio of chalcogen to metal through the time-dependent characterizations,and the non-stoichiometric ratios in TMCs reveal the atomic lattices with point defects like additive bonds or vacancies inside.This study not only provides a potential view to fabricate environmentally stable TMCs based devices,but also will bring an effective feasibility of stacking stable vertical heterostructures. | Zhenjia Zhou Tao Xu Chenxi Zhang Shisheng Li Jie Xu Litao Sun Libo Gao | 2021 | Nano Research2021，14，6： | 2 |
| 12 | Clinical features and risk factors for post-partum depression in a large cohort of Chinese women with recurrent major depressive disorder显示文摘 | Tian Tian Yihan Li Dong Xie Yifeng Shen Jianer Ren Wenyuan Wu Chengbin Guan Zhen Zhang Danning Zhang Chengge Gao Xiaoming Zhang Jinbo Wu Hong Deng Gang Wang Yunshu Zhang Yun Shao Han Rong Zhaoyu Gan Yan Sun Bin Hu Jiyang Pan Yi Li Shufan Sun Libo Song Xue | 2011 | Journal of Affective Disorders2011，，3： | 1 |
| 13 | Discoidin domain receptor 2 is associated with the increased expression of matrix metalloproteinase-13 in synovial fibroblasts of rheumatoid arthritis显示文摘 | Jin Su Jiangtian Yu Tingting Ren Wei Zhang Yuanqiang Zhang Xinping Liu Tiezheng Sun Houshan Lu Keiji Miyazawa Libo Yao | 2009 | 2009 (1-2)2009，，1： | 1 |
| 14 | Functional Analysis of Discoidin Domain Receptor 2 in Synovial Fibroblasts in Rheumatoid Arthritis显示文摘 | Jicun Wang Houshan Lü Xinping Liu Yanchun Deng Tiezheng Sun Fuyang Li Shaoping Ji Xiaoyan Nie Libo Yao | 2002 | Journal of Autoimmunity2002，，3： | 1 |
| 15 | Controllable synthesis and luminescent properties of three-dimensional nanostructured CaWO 4 :Tb 3+ microspheres显示文摘 | Yue Tian Baojiu Chen Hongquan Yu Ruinian Hua Xiangping Li Jiashi Sun Lihong Cheng Haiyang Zhong Jinsu Zhang Yanfeng Zheng Tingting Yu Libo Huang | 2011 | Journal of Colloid And Interface Science2011，，2： | 1 |
| 16 | Three-dimensional printed tissue engineered bone for canine mandibular defects显示文摘Background:Three-dimensional(3D)printed tissue engineered bone was used to repair the bone tissue defects in the oral and maxillofacial(OMF)region of experimental dogs.Material and methods:Canine bone marrow stromal cells(BMSCs)were obtained from 9 male Beagle dogs and in vitro cultured for osteogenic differentiation.The OMF region was scanned for 3D printed surgical guide plate and mold by ProJet1200 high-precision printer using implant materials followed sintering at 1250℃.The tissue engineered bones was co-cultured with BASCs for 2 or 8 d.The cell scaffold composite was placed in the defects and fixed in 9 dogs in 3 groups.Postoperative CT and/or micro-CT scans were performed to observe the osteogenesis and material degradation.Results:BMSCs were cultured with osteogenic differentiation in the second generation(P2).The nanoporous hydroxyapatite implant was made using the 3D printing mold with the white porous structure and the hard texture.BMSCs with osteogenic induction were densely covered with the surface of the material after co-culture and ECM was secreted to form calcium-like crystal nodules.The effect of the tissue engineered bone on the in vivo osteogenesis ability was no significant difference between 2 d and 8 d of the compositing time.Conclusions:The tissue-engineered bone was constructed by 3D printing mold and hightemperature sintering to produce nanoporous hydroxyapatite scaffolds,which repair in situ bone defects in experimental dogs.The time of compositing for tissue engineered bone was reduced from 8 d to 2 d without the in vivo effect. | Li Zhang Junling Tang Libo Sun Ting Zheng Xianzhi Pu Yue Chen Kai Yang | 2020 | Genes & Diseases2020，7，1： | 1 |
| 17 | Synthesis and characterization of SnO 2 /polyaniline nanocomposites by sol–gel technique and microemulsion polymerization显示文摘 | Libo Sun Yuanchang Shi Zhaopin He Bo Li Jiurong Liu | 2012 | Synthetic Metals2012，，24： | 1 |
| 18 | Measurement of Martian atmospheric winds by the O_(2) 1.27 μm airglow observations using Doppler Michelson Interferometry: A concept study显示文摘China’s Mars exploration mission has stimulated tremendous interest in planetary science exploration recently.To propose potential scientific research projects,this study presents a concept simulation for the measurement of Martian atmospheric winds using the Doppler Michelson interferometry technique.The simulation is based on the satellite instrument initially designed for the Dynamic Atmosphere Mars Observer(DYNAMO)project to measure vertical profiles of winds from the 1.27μm airglow observations in the Martian atmosphere.A comprehensive DYNAMO measurement simulation forward model based on an orbit submodel,an atmospheric background field submodel,and an instrument submodel is developed using the Michelson equation.The simulated interferogram signal over the field of view(FOV)calculated by the forward model is associated with the filter transmittance function,column emission rate of airglow,wind velocity,temperature,and the Michelson phase.The agreement between the derived atmospheric signals from the simulated interferogram without altitude inversion and the input parameters used to initiate the forward model confirms the validity of the forward model. | Na YANG Chunliang XIA Tao YU Xiaomin ZUO Yangyi SUN Xiangxiang YAN Jian ZHANG Jin WANG Huijun LE Libo LIU William Edmund WARD | 2021 | Science China Earth Sciences2021，64，11： | 1 |
| 19 | Correlation of gut microbiota and neurotransmitters in a rat model of post-traumatic stress disorder显示文摘Objective:To determine the effect of gut microbiota on a rat model of post-traumatic stress disorder(PTSD)and explore the correlation of gut microbiota with behavior and neurotransmitters.Methods:We established a single prolonged stress(SPS)model to examine the pathogenesis of PTSD on rat behavior,gut microbiota,and neurotransmitter levels.Rats were separated into control and model groups,and neurotransmitter levels were measured using enzyme linked immunosorbent assay.Then,16 S rRNA sequencing was used to compare the gut microbiota between the control and model groups.Results:Compared with those in the control group,freezing time significantly increased,while number of standing upright,crossing frequency,time spent in the central arena,and total distance traveled were significantly reduced in the model group after exposure to SPS(all P<.05).Meanwhile,serotonin,or 5-hydroxytryptamine,levels in the brain in the model group were significantly lower than those the control group(P紏.0332).In addition,changes were observed in the gut microbiota diversity and relative abundances of bacterial phyla,orders,families,and genera in the model group.Especially,changes in Firmicutes,Bacteroidetes,Cyanobacteria,and Proteobacteria levels were most pronounced after SPS exposure.Correlation analysis showed that the strongest positive correlation was found between Bacteroidaceae and 5-HT(P?.0009).Moreover,RF32 abundance was the most negatively related to 5-HT(P?.0009),crossing frequency(P?.0007),and total distance(P?.0003).Conclusion:Our results suggest that SPS model rats showed differences in behavior,neurotransmitter levels,and gut microbiota with control rats.Moreover,Firmicutes,Bacteroidetes,Cyanobacteria,and Proteobacteria were most relevant to the exhibited fear-like and anxiety-like behaviors and significant serotonin content reduction in SPS model rats. | Qin Zhou Tianshi Sun Fengzhi Wu Feng Li Yan Liu Weihong Li Ning Dai Libo Tan Tenghui Li Yuehan Song | 2020 | Journal of Traditional Chinese Medical Sciences2020，7，4： | 1 |
| 20 | Highly selective and efficient electroreduction of CO_(2) in water by quaterpyridine derivative‐based molecular catalyst noncovalently tethered to carbon nanotubes显示文摘A disubstituted quaterpyridine based cobalt complex non‐covalently tethered to multiwalled carbon nanotube(MWCNT)substrate,forming a hybrid catalyst,Co‐qpyCOOH/CNT,catalyzed the conversion of CO_(2) to CO under aqueous conditions.At an optimal and uniform loading,it exhibited remarkable catalytic activity,near‐exclusive selectivity,and high stability towards the formation of CO.At a mere cathodic potential of−0.65 V versus RHE(η=0.54 V),it achieved a high partial current density of−6.7 mA/cm^(2) and a F.E.CO=100%.In addition,with 20 h of stable operation,hydrogen evolution remained practically undetected.Its hybrid structure due to noncovalent immobilization on MWCNT imparted the intrinsic activity and much‐needed stability in performance whereas‒COOH groups may stabilize the intermediates by acting as H‐bond donors,promoting catalytic activity.Tethering to a conductive solid substrate and tuning of the second sphere of coordination played an important role in its performance to achieve desired reduction product with high selectivity and activity. | Vikas Reddu Libo Sun Xiaogang Li Huile Jin Shun Wang Xin Wang | 2022 | SmartMat2022，3，1： | 1 |
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