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| 1 | Factor analysis identifies subgroups of constipation显示文摘AIM:To determine whether distinct symptom groupings exist in a constipated population and whether such grouping might correlate with quantifiable pathophysiological measures of colonic dysfunction.METHODS:One hundred and ninety-one patients presenting to a Gastroenterology clinic with constipation and 32 constipated patients responding to a newspaper advertisement completed a 53-item,wide-ranging selfreport questionnaire.One hundred of these patients had colonic transit measured scintigraphically.Factor analysis determined whether constipation-related symptoms grouped into distinct aspects of symptomatology.Cluster analysis was used to determine whether indi-vidual patients naturally group into distinct subtypes.RESULTS:Cluster analysis yielded a 4 cluster solution with the presence or absence of pain and laxative unresponsiveness providing the main descriptors.Amongst all clusters there was a considerable proportion of patients with demonstrable delayed colon transit,irritable bowel syndrome positive criteria and regular stool frequency.The majority of patients with these characteristics also reported regular laxative use.CONCLUSION:Factor analysis identified four constipation subgroups,based on severity and laxative unresponsiveness,in a constipated population.However,clear stratification into clinically identifiable groups remains imprecise. | Philip G Dinning Mike Jones Linda Hunt Sergio E Fuentealba Jamshid Kalanter Denis W King David Z Lubowski Nicholas J Talley Ian J Cook | 2011 | World Journal of Gastroenterology2011，17，11： | 3 |
| 2 | Perioperative risk factors associated with delayed graft function following deceased donor kidney transplantation:A retrospective,single center study显示文摘BACKGROUND There is an abundant need to increase the availability of deceased donor kidney transplantation(DDKT)to address the high incidence of kidney failure.Challenges exist in the utilization of higher risk donor organs into what appears to be increasingly complex recipients;thus the identification of modifiable risk factors associated with poor outcomes is paramount.AIM To identify risk factors associated with delayed graft function(DGF).METHODS Consecutive adults undergoing DDKT between January 2016 and July 2017 were identified with a study population of 294 patients.The primary outcome was the occurrence of DGF.RESULTS The incidence of DGF was 27%.Under logistic regression,eight independent risk factors for DGF were identified including recipient body mass index≥30 kg/m^(2),baseline mean arterial pressure<110 mmHg,intraoperative phenylephrine administration,cold storage time≥16 h,donation after cardiac death,donor history of coronary artery disease,donor terminal creatinine≥1.9 mg/dL,and a hypothermic machine perfusion(HMP)pump resistance≥0.23 mmHg/mL/min.CONCLUSION We delineate the association between DGF and recipient characteristics of preinduction mean arterial pressure below 110 mmHg,metabolic syndrome,donorspecific risk factors,HMP pump parameters,and intraoperative use of phenylephrine. | Nicholas V Mendez Yehuda Raveh Joshua J Livingstone Gaetano Ciancio Giselle Guerra George W Burke III Vadim B Shatz Fouad G Souki Linda J Chen Mahmoud Morsi Jose M Figueiro Tony M Ibrahim Werviston L DeFaria Ramona Nicolau-Raducu | 2021 | World Journal of Transplantation2021，11，4： | 2 |
| 3 | Probiotics stimulate liver and plasma protein synthesis in piglets with dextran sulfate induced colitis and macronutrient restriction显示文摘 | Scott V H Keely G F Linda J W | 2008 | Journal of Nutrition2008，138，： | 1 |
| 4 | Differences in replication of a DNA template containing an ethyl phosphotriester by T4 DNA polymerase and Escherichia coli DNA polymerase I显示文摘 | Laura T Michael W Linda J | | 0，，17： | 1 |
| 5 | Liquefaction of Autographa californica Nucleopolyhedrovirus-Infected Insects Is Dependent on the Integrity of Virus-Encoded Chitinase and Cathepsin Genes显示文摘 | Rachael E Hawtin Tamara Zarkowska Kevin Arnold Carole J Thomas Graham W Gooday Linda A King John A Kuzio Robert D Possee | 1997 | Virology1997，，： | 1 |
| 6 | Effects of substrata on the polarization of bovine endometrial epithelial cells in vitro 显示文摘 | Linda M J Erby W Donald H S | 1990 | Cell and Tissue Research1990，261，1： | 1 |
| 7 | Oral combination therapy with a nucleoside polymerase inhibitor (RG7128) and danoprevir for chronic hepatitis C genotype 1 infection (INFORM-1): a randomised, double-blind, placebo-controlled, dose-escalation trial显示文摘 | Edward J Gane Stuart K Roberts Catherine AM Stedman Peter W Angus Brett Ritchie Rob Elston David Ipe Peter N Morcos Linda Baher Isabel Najera Tom Chu Uri Lopatin M Michelle Berrey William Bradford Mark Laughlin Nancy S Shulman Patrick F Smith | 2010 | The Lancet2010，，9751： | 1 |
| 8 | Diagnosis, assessment, and treatment of bone turnover abnormalities in renal osteodystrophy显示文摘 | Kevin J Martin Klaus Olgaard Jack W Coburn Giorgio M Coen Masafumi Fukagawa Craig Langman Hartmut H Malluche James T McCarthy Shaul G Massry Otto Mehls Isidro B Salusky Justin M Silver Miroslaw T Smogorzewski Eduardo M Slatopolsky Linda McCann | 2004 | American Journal of Kidney Diseases2004，，3： | 1 |
| 9 | Use the power of sonocrystallization for improved properties显示文摘 | Linda J McCausland Peter W Cains Peter D Martin | 2001 | Chemical Engineering Progress2001，97，7： | 1 |
| 10 | Continuous Hydrothermal Synthesis of CoFe2O4 Nanoparticles显示文摘 | Linda J C Amyn S T Angus P W | 2003 | Fluid Phase Equilibria2003，210，2： | 1 |
| 11 | Liver transplantation and health-related quality of life: Scoring differences between men and women显示文摘 | Terianne C Linda W J ennings | 2004 | Liver Trnsplantation2004，10，1： | 1 |
| 12 | Removal of cyanobacterial toxins(microcystins)and cyanobacterial cells from drinking water using domestic waterfilter显示文摘 | Linda A Lawton Benjamin J P A Cornish Andrew W R Macdonald | 1998 | Wat Res1998，32，3： | 1 |
| 13 | Assessing group efficacy-comparing three methods of measurement显示文摘 | Whiteoak J W Chalip Laurence Hort Linda K | 2004 | Small Group Research2004，35，2： | 1 |
| 14 | Removal of cyanobacterial toxins(microcystins)and cyanobacterial cells from drinking water using domestic water filters显示文摘 | LINDA A L BENJAMIN J P ANDREW W R | 1998 | Wat Res1998，32，： | 1 |
| 15 | Early and late coronary stent thrombosis of sirolimus-eluting and paclitaxel-eluting stents in routine clinical practice: data from a large two-institutional cohort study显示文摘 | Joost Daemen Peter Wenaweser Keiichi Tsuchida Linda Abrecht Sophia Vaina Cyrill Morger Neville Kukreja Peter Jüni Georgios Sianos Gerrit Hellige Ron T van Domburg Otto M Hess Eric Boersma Bernhard Meier Stephan Windecker Patrick W Serruys | 2007 | The Lancet2007，，9562： | 1 |
| 16 | Probiotics stimulate liver and plasma protein synthesis in piglets with dextran sulfate-induced colitis and macronutrient restriction 显示文摘 | SCOTT V H KEELY G F LINDA J W | 2008 | Journal of Nutrition2008，138，： | 1 |
| 17 | Probiotics stimulate liver and plasma protein synthesis in piglets with dextran sulfate-in- duced colitis and macronutrient restriction 显示文摘 | Scott V H Keely G F Linda J W | 2008 | The Journal of Nutrition2008，138，11： | 1 |
| 18 | Alliin lyase (alliinase) from garlic (Allium sativum):crystallization and preliminary X-ray characterization显示文摘 | Shimon Linda J W Rabinkov Aharon Miron Talia Mirelman David Wilchek Meir Frolow Felix | 2002 | Acta Crystallographica Biological Crystallography2002，58，8： | 1 |
| 19 | Low-Pressure Hydrogenation of Carbon Dioxide Catalyzed by an Iron Pincer Complex Exhibiting Noble Metal Activity显示文摘 | Robert Langer Yael Diskin-Posner Gregory Leitus Linda Shimon J W Yehoshoa Ben-David David Milstein | 2011 | Angew Chem Int Ed2011，50，： | 1 |
| 20 | Financial intermediary versus production approach to efficiency of marketing distribution systems and organizational structure of insurance companies 显示文摘 | Patrick L Brockett William W Cooper Linda L Golden John J Rousseau Yuying Wang | 2005 | Journal of Risk and Insurance2005，72，3： | 1 |
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