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| 1 | Characterization of a critical role for CFTR chloride channels in cardioprotection against ischemia/ reperfusion injury显示文摘目的: 进一步描绘膀胱的纤维变性 transmembrane 传导力管理者(CFTR ) 的功能的角色在早、迟了(第二扇窗户) ischemic preconditioning (欧洲电脑生产厂商)- 并且 postconditioning (停靠港) 调停了对 ischemia/reperfusion (I/R ) 的 cardioprotection 损害。 | Sunny Yang XIANG Linda L YE Li-lu Marie DUAN Li-hui LIU Zhi-dong GE John A AUCHAMPACH Garrett J GROSS Dayue Darrel DUAN | 2011 | Acta Pharmacologica Sinica2011，32，6： | 9 |
| 2 | Gamma irradiation of HIV-1显示文摘 | Richard A Smith Jesse Ingels John J Lochemes Joseph P Dutkowsky Linda L Pifer | 2001 | Journal of Orthopaedic Research2001，，5： | 2 |
| 3 | Non-steroidal anti-inflammatory drugs and risk of neoplastic progression in Barrett’s oesophagus: a prospective study显示文摘 | Thomas L Vaughan Linda M Dong Patricia L Blount Kamran Ayub Robert D Odze Carissa A Sanchez Peter S Rabinovitch Brian J Reid | 2005 | Lancet Oncology2005，，12： | 2 |
| 4 | Factors associated with 5-year survival of combined hepatocellular and cholangiocarcinoma显示文摘BACKGROUND Combined hepatocellular and cholangiocarcinoma(HCC/CC)is a rare primary hepatic malignancy which carries a poor prognosis due to its aggressive nature.Few centers have enough cases to draw definitive conclusions and there is limited understanding of prognosis.Given the rarity of HCC/CC,an analysis of large national cancer database was needed to obtain larger number of HCC/CC cases.AIM To identify associated factors for 5-year survival of HCC/CC.METHODS We conducted a retrospective study of The Surveillance,Epidemiology,and End Results(SEER)database obtained from SEER*Stat 8.3.6 software.Previously defined histology code 8180 for the International Classification of Disease for Oncology,3rd edition was used to identify HCC/CC cases from 2004 to 2015.We collected demographics,American Joint Committee on Cancer(AJCC)stage,treatment,tumor size,and survival data.These data were converted to categorical variables.The Shapiro-Wilk normality test was used to assess normal distribution.Mann-Whitney U test was used to compare continuous variables without normal distribution,and t-test was used to compare continuous variables with a normal distribution.The Kaplan-Meier survival curve analyzed 5-year survival.Univariate and multivariate logistic regression model was used to analyze factors associated with 5-year survival.Multivariate Cox proportional hazard regression was done on 5-year survival.We defined P<0.05 was statistically significant.RESULTS We identified 497 patients with the following characteristics:Mean age 62.4 years(SD:11.3),149(30.0%)were female,racial distribution was:276(55.5%)white,53(10.7%)black,84(16.9%)Asian and Pacific Islander(API),77(15.5%)Hispanic,and 7(1.4%)others or unknown.Stage I/II disease occurred in 41.5%and tumor size<50 mm was seen in 35.6%of patients.Twenty-four(4.8%)received locoregional therapy(LRT),119(23.9%)underwent resection,and 50(10.1%)underwent liver transplantation.The overall median survival was 6 mo[Interquartile range(IQR):1-22].After multivariate logistic regression,tumor size<50 mm[Odds ratios(OR):2.415,P=0.05],resection(OR:12.849,P<0.01),and transplant(OR:27.129,P<0.01)showed significance for 5-year survival.Age>60,sex,race,AJCC stages,metastasis,and LRT were not significant.However,API vs white showed significant OR of 2.793(CI:1.120-6.967).Cox proportional hazard regression showed AJCC stages,tumor size<50 mm,LRT,resection,and transplant showed significant hazard ratio.CONCLUSION HCC/CC patients with tumor size<50 mm,resection,and transplant were associated with an increase in 5-year survival.API showed advantageous OR and hazard ratios over white,black. | Tomoki Sempokuya Eric A Wien Robert J Pattison Jihyun Ma Linda L Wong | 2020 | World Journal of Hepatology2020，12，11： | 2 |
| 5 | Circulating CD40+and CD86+B cell subsets demonstrate opposing associations with risk of stroke显示文摘 | Mantani P T Irena L Linda A | 2014 | Arteriosclerosis Thrombosis&Vascular Biology2014，34，1： | 1 |
| 6 | Renal outcomes with different fixed-dose combination therapies in patients with hypertension at high risk for cardiovascular events (ACCOMPLISH): a prespecified secondary analysis of a randomised controlled trial显示文摘 | George L Bakris Pantelis A Sarafidis Matthew R Weir Bj?rn Dahl?f Bertram Pitt Kenneth Jamerson Eric J Velazquez Linda Staikos-Byrne Roxzana Y Kelly Victor Shi Yann-Tong Chiang Michael A Weber | 2010 | The Lancet2010，，9721： | 1 |
| 7 | Molecular and phenotypic characterization of Als1 and Als2 mutations conferring tolerance to acetolactate synthase herbicides in soybean显示文摘 | Kay L Walter Stephen D Strachan Nancy M Ferry Henrik H Albert Linda A Castle Scott A Sebastian | 2014 | Pest. Manag. Sci2014，，12： | 1 |
| 8 | Use of amino-terminal pro-B-type natriuretic peptide to guide outpatient therapy of patients with chronic left ventricular systolic dysfunction 显示文摘 | JAMES L JANUZZI JR MD SHAFIQ U REHMAN M D ASIM A MOHAMMED M D ANJU BHARDWAJ M D LINDA BARAJAS R N JUSTINE BARAJAS HAN-NA KIM M D MPH AARON L BAGGISH M D RORY B WEINER M D ANNABEL CHEN-TOURNOUX MD JANE E MARSHALL RDCS STEPHANIE A MOORE M D WILLIAM D CARLSON M D GREGORY D LEWIS M D JORDAN SHIN M D DOROTHY SULLIVAN ANP KIMBERLY PARKS D O THOMAS J WANG M D SHAWN A GREGORY M D SHANMUGAM UTHAMALINGAM M D MARC J SEMIGRAN M D | 2011 | J Am Coll Cardiol2011，58，18： | 1 |
| 9 | Sorption of Three Tetracyclines by Several Soils: Assessing the Role of pH and Cation Exchange 显示文摘 | Stephen A S Linda S L | 2005 | Environ Sci Technol2005，39，： | 1 |
| 10 | Brain activation and sexual arousal in healthy,heterosexual males显示文摘 | Bruce A John E Linda L | 2002 | Brain ProQuest Medical Library2002，125，5： | 1 |
| 11 | Forming Activated Sudge Plants: A survey in Queensland, Australia and an Evaluation of Some Control Strategies显示文摘 | Linda L B Harbers A E Greenfield P F | 1991 | Water Research1991，25，3： | 1 |
| 12 | Plasma monocyte chemotactic protein-1 remains elevated after minimally invasive colorectal cancer resection显示文摘AIM: To investigate plasma Monocyte Chemotactic Protein-1 levels preoperatively in colorectal cancer(CRC) and benign patients and postoperatively after CRC resection.METHODS: A plasma bank was screened for minimally invasive colorectal cancer resection(MICR) for CRC and benign disease(BEN) patients for whom preoperative, early postoperative, and 1 or more late postoperative samples(postoperative day 7-27) were available. Monocyte chemotactic protein-1(MCP-1) levels(pg/mL) were determined via enzyme linked immuno-absorbent assay. RESULTS: One hundred and two CRC and 86 BEN patients were studied. The CRC patient's median preoperative MCP-1 level(283.1, CI: 256.0, 294.3) was higher than the BEN group level(227.5, CI: 200.2, 245.2; P = 0.0004). Vs CRC preoperative levels, elevated MCP-1 plasma levels were found on postoperative day 1(446.3, CI: 418.0, 520.1), postoperative day 3(342.7, CI: 320.4, 377.4), postoperative day 7-13(326.5, CI: 299.4, 354.1), postoperative day 14-20(361.6, CI: 287.8, 407.9), and postoperative day 21-27(318.1, CI: 287.2, 371.6; P < 0.001 for all). CONCLUSION: Preoperative MCP-1 levels were higher in CRC patients(vs BEN). After MICR for CRC, MCP-1 levels were elevated for 1 mo and may promote angiogenesis, cancer recurrence and metastasis. | HMC Shantha Kumara Elizabeth A Myers Sonali AC Herath Joon Ho Jang Linda Njoh Xiaohong Yan Daniel Kirchoff Vesna Cekic Martin Luchtefeld Richard L Whelan | 2014 | World Journal of Gastrointestinal Oncology2014，6，10： | 1 |
| 13 | Combinatorial discovery of tumortargeting peptides using phage display显示文摘 | Linda A Landonl Susan L | 2003 | J Cell Biochem2003，90，： | 1 |
| 14 | Sorption of three tetracyclines by several soils:assessing the role of pH and cation exchange显示文摘 | Stephen A S Linda S L | 2005 | Environment Science and Technology2005，39，： | 1 |
| 15 | Sorption of three tetracyclines by several soils: Assessing the role of pH and cation exchange显示文摘 | Stephen A S Linda S L | 2005 | Environmental Science Technology2005，39，： | 1 |
| 16 | Monitoring ultrathin film photopoly- merization of tetra-alkylepoxyporphyrin by UV-Vis spectroscopy显示文摘 | Kalle L Linda S Alexander E Sami H Risto A Nikolai T Helge L | 2009 | Journal of Polymer Science Part A: Polymer Chemistry2009，47，22： | 1 |
| 17 | Suppression of the root-lesion (Pratylenchuspenetrans) in alfalfa (Medicago sativa) by Streptomyces pp 显示文摘 | Deborah A S Linda L K | 2001 | Journal of Plant and Soil2001，235，： | 1 |
| 18 | Mechanistic and toxicity studies of the photocatalytic oxidation of microcystin-LR显示文摘 | Linda A L Ben C | 2002 | Journal of Photochemistry and Photobiology A:Chemistry2002，148，： | 1 |
| 19 | Increasing hydrophobicity of sol-gel hard coating by chemical and morphological modifications显示文摘 | Wu Linda Y L Soutar A M Zeng X T | 2005 | Surface and Coatings Technology2005，198，： | 1 |
| 20 | Mechanistic and oxideity studies of the photocatalytic oxidation of microcystin-LR 显示文摘 | IAIN L LINDA A L BEN C | 2002 | Chemistry2002，148，13： | 1 |
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