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22篇 您的检索式：作者名="LEADER E"

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	题名	作者	年代	出处	被引量
1	胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。	Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉叶鹏	2017	中华高血压杂志2017，25，9：	2
2	Phosphorus sorbing materials : sorption dynamics and physicochemical characteristics 显示文摘	Leader J W Dunne E J Reddy K R	2008	Journal of Environment Quality2008，37，1：	1
3	Analysis of p16 expression and allelic imbalance// loss of heterozygosity of 9p21 in cutaneous squamous cell carcinomas显示文摘	Gray SE Kay E Leader M	2006	J Cell Mol Med2006，10，3：	1
4	The problem with KIT: clinical implications and practical difficulties with CDll7 immunostaining显示文摘	Sabah M Leader M Kay E	2003	Appl Immunohistochem Mol Morphol2003，11，1：	1
5	Protein therapeutics: a summary and pharmacological classification显示文摘	Leader B Baca Q J Golan D E	2008	Nat Rev Drug Discoy2008，7，1：	1
6	Role of higher twist in polarized deep inelastic scattering 显示文摘	LEADER E SIDOROV A V STAMENOV D B	2003	Physical Review D2003，67，074017：	1
7	Phosphorus sorbing materials: sorption dynamics and physicochemical characteris- tics显示文摘	LEADER J W DUNNE E J REDDY K R	2008	Journal of Environment Quality2008，37，1：	1
8	The problem with KIT:clinical implications and practical difficulties with CD117 immunostaining显示文摘	SABAH M LEADER M KAY E	2003	Appl Immunohistochem Mol Morphol2003，11，1：	1
9	Emissions of volatile organic compounds from building materials and consumer products显示文摘	Wallace LA Pellizzari E Leaderer B	1987	Atmos Environ1987，21，2：	1
10	Telomerase activity detected in oral lichen planus by RNA in situ hybridisation: not a marker for malignant transfo rmation显示文摘	O'Flatharta C Leader M Kay E	2002	J Clin Pathol2002，55，8：	1
11	Dust mite, cockroach, cat, and dog allergen concentrations in homes of asthmatic children in the Northeastern United States 显示文摘	LEADERER B P BELANGER K TRICHE E	2002	Environmental Health Perspectives2002，，5：	1
12	The histone deacetylase inhibitor sodium butyrate induces DNA topoisomerase Ⅱ expression and confers hypersensitivity to etoposide in human leukemic cell lines 显示文摘	Sara E'Wilson Kelly B'Leader	2001	Molecular Cancer Therapeutics2001，1，2：	1
13	Epigenetics and the estrogenreceptor显示文摘	Leader J E Wang C Popov V M	2006	Ann N Y Acad Sci2006，1089，1：	1
14	Analysis of FHIT allelic imbal-ance/loss of heterozygosity and FHIT expression in coetaneoussquamous cell carcinomas显示文摘	Gray SE Kay E Leader M	2008	J Cutan Pathol2008，35，9：	1
15	Protein therapeutics: a summary and pharmacological classification 显示文摘	Leader B Baca Q J Golan D E	2008	Nat Rev Drug Discov2008，7，1：	1
16	PC-SPES: herbal formuation for prostate cancer 显示文摘	Marks L S DiPaola R S Nelson P Chen S Heber D Belldegrun A S Lowe F C Fan J Leaders F E Pantuck A J Tyler V E	2002	Urology2002，60，3：	1
17	The problem with KIT: clinical implications and practical difficulties with CD117 immunostaining显示文摘	Sabah M Leader M Kay E	2003	Appl Immunohistochem Mol Morphol2003，11，1：	1
18	The problem with KIT:clinical-implications and practical difficulties with CD117 immunostaining显示文摘	Sabah M Leader M Kay E	2003	Appl Immunohistochem Mol Morphol2003，11，1：	1
19	Epigenetics and the estrogen receptor 显示文摘	LEADER J E WANG C POPAV V M	2006	Ann N Y Acad Sci2006，1089，：	1
20	The relationship between cyclooxygenase-2 expression and characteristics of malignant transformation in human colorectal adenomas显示文摘	Katherine M Sheehan Fionnuala O’Connell Anthony O’Grady Ronan M Conroy Mary B Leader Michael F Byrne Frank E Murray Elaine W Kay	2004	European Journal of Gastroenterology & Hepatology2004，，6：	1

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