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| 1 | Neoadjuvant radiotherapy for rectal cancer management显示文摘Thirty per cent of all colorectal tumours develop in the rectum.The location of the rectum within the bony pelvis and its proximity to vital structures presents significant therapeutic challenges when considering neoadjuvant options and surgical interventions.Most patients with early rectal cancer can be adequately managed by surgery alone.However,a significant proportion of patients with rectal cancer present with locally advanced disease and will potentially benefit from down staging prior to surgery.Neoadjuvant therapy involves a variety of options including radiotherapy,chemotherapy used alone or in combination.Neoadjuvant radiotherapy in rectal cancer has been shown to be effective in reducing tumour burden in advance of curative surgery.The gold standard surgical rectal cancer management aims to achieve surgical removal of the tumour and all draining lymph nodes,within an intact mesorectal package,in order to minimise local recurrence.It is critically important that all rectal cancer cases are discussed at a multidisciplinary meeting represented by all relevant specialties.Pre-operative staging including CT thorax,abdomen,pelvis to assess for distal disease and magnetic resonance imaging to assess local involvement is essential.Staging radiology and MDT discussion are integral in identifying patients who require neoadjuvant radiotherapy.While Neoadjuvant radiotherapy is potentially beneficial it may also result in morbidity and thus should be reserved for those patients who are at a high risk of local failure,which includes patients with nodal involvement,extramural venous invasion and threatened circumferential margin.The aim of this review is to discuss the role of neoadjuvant radiotherapy in the management of rectal cancer. | Gerard Feeney Rishabh Sehgal Margaret Sheehan Aisling Hogan Mark Regan Myles Joyce Michael Kerin | 2019 | World Journal of Gastroenterology2019，25，33： | 28 |
| 2 | 脑动静脉畸形的处理:美国心脏协会/美国卒中协会对医疗卫生专业人员发布的科学声明显示文摘背景本声明旨在复习目前脑动静脉畸形(brain arteriovenous malformations,bAVMs)的临床资料,为破裂或未破裂bAVMs的诊断和治疗提供建议。方法写作组通过面谈和电话会议的方式确定搜索关键词,讨论描述性文字和制定建议。作者通过PubMed、Medline或Embase完成各自相关章节的文献检索,时间截止到2015年1月底。声明草稿由同行评议专家以及卒中委员会科学监督委员会和卒中委员会领导委员会进行预先审查。结果本科学声明的重点细分为流行病学、诊断、自然史、治疗方案(包括开颅手术、立体定向放射外科和栓塞治疗的作用)以及破裂和未破裂bAVMs的处理,并且确定了需要更多证据支持的领域。结论bAVMs是一种相对少见但非常重要的出血性卒中病因,尤其是在年轻成人中。本声明描述了目前关于破裂和未破裂bAVMs的自然史和治疗方法的知识现状,同时提供了处理建议以及对将来研究的提示。 | Colin P. Derdeyn Gregory J. Zipfel Felipe C. Albuquerque Daniel L. Cooke Edward Feldmann Jason P. Sheehan James C. Tomer 盖延廷 王威 简新革 檀书斌 李彦江 彭方强 刘旻谛 宋冬雷 | 2017 | 国际脑血管病杂志2017，25，8： | 12 |
| 3 | 5种源尘表面特征的分析显示文摘运用扫描电镜和X射线能谱分析枝术,对太原市5种大气源尘的表面特征进行分析,结果显示各源尘均具有各自的特征元素和形态特性;工业冶金尘的Fe、建材尘的Ca和汽车尘的Pb为其特征峰。燃煤尘和土壤尘表面元素组分相似,均以Al和Si为主.但形态截然不同,前者颗粒小为圆形,后者颗粒大,形状不规则。 | 杨文敏 赵毓梅 马亚萍 Christine Sheehan | 1996 | 中国公共卫生学报1996，15，4： | 9 |
| 4 | Nonlinear Bend Stiffener Analysis Using A Simple Formulation and Finite Element Method显示文摘Flexible marine risers are commonly used in deepwater floating systems.Bend stiffeners are designed to protect flexible risers against excessive bending at the connection with the hull.The structure is usually analyzed as a cantilever beam subjected to an inclined point load.As deflections are large and the bend stiffener material exhibits nonlinear stress-strain characteristics,geometric and material nonlinearities are important considerations.A new approach has been developed to solve this nonlinear problem.Its main advantage is its simplicity;in fact the present method can be easily implemented on a spreadsheet.Finite element analysis using ABAQUS is performed to validate the method.Solid elements are used for the bend stiffener and flexible pipe.To simulate the near inextensibility of flexible risers,a simple and original idea of using truss elements is proposed.Through a set of validation studies,the present method is found to be in a good agreement with the finite element analysis.Further,parametric studies are performed by using both methods to identify the key parameters and phenomena that are most critical in design.The most important finding is that the common practice of neglecting the internal steel sleeve in the bend stiffener analysis is non-conservative and therefore needs to be reassessed. | TONG Dong Jin LOW Ying Min SHEEHAN John M | 2011 | China Ocean Engineering2011，25，4： | 6 |
| 5 | 肾移植:应用磁化准备稳态自由进动技术行肾血管非增强MRA检查显示文摘机构审查委员会批准本项符合HIPAA标准的研究,具有知情同意豁免权。目的是研究反转恢复稳态自由进动(steady—state free precession,SSFP)非增强MRA技术在评估肾移植病人肾动脉中的价值。13例接受肾移植者于对比增强MRA检查前行SSFP MRA检查。SSFP MRA提示3处狭窄(2处轻度狭窄,1处重度狭窄),与对比增强MRA一致。2种成像方法的影像质量差异无统计学意义。结果提示SSFP MRA在肾移植动脉成像质量及检测动脉狭窄方面, | X. Liu N. Berg J. Sheehan X. Bi P. Weale R. Jerecic 刘丽华(译) 季倩(校) | 2009 | 国际医学放射学杂志2009，32，4： | 6 |
| 6 | Clinical and pathological characteristics of brain metastasis resected after failed radiosurgery显示文摘 | Jagannathan J Bourne TD Schlesinger D Yen CP Shaffrey ME Laws ER Jr Sheehan JP. | 2010 | 中国神经肿瘤杂志2010，8，1： | 4 |
| 7 | 中国人工智能兴起的原因及其经济意义显示文摘中国在扮演了将近四十年世界工厂的角色之后,正逐渐成为人工智能创新应用的中心。预计至2030年,人工智能将为全球创造15.7万亿美元的财富,其中7万亿美元的财富将由中国创造。为何中国能在人工智能领域迅速跻身国际先进国家行列?这将对中国甚至全球经济产生怎样的影响?本文将从以下三个方面进行回答:人工智能最新进展的本质. | 李开复 Matt Sheehan | 2019 | 智慧中国2019，0，4： | 3 |
| 8 | Private placements and managerial entrenchment显示文摘 | Michael J. Barclay Clifford G. Holderness Dennis P. Sheehan | 2007 | Journal of Corporate Finance2007，，4： | 3 |
| 9 | Three-dimensional echocardiographic assessment of annular shape changes in the normal and regurgitant mitral valve显示文摘 | Kaplan SR Bashein G Sheehan FH | 2000 | Am Heart J2000，139，3： | 2 |
| 10 | Endoscopic Mucosal Resection of an Epstein–Barr Virus-Associated Lymphoepithelioma-Like Gastric Carcinoma显示文摘 | Shou-jiang Tang Naveed Ahmed Feriyl Bhaijee John Sheehan Charu Subramony Courtney Jackson Jack R. Lewin | 2012 | Digestive Diseases and Sciences2012，，11： | 2 |
| 11 | The prognostic value of tumour regression grade following neoadjuvant chemoradiation therapy for rectal cancer显示文摘 | K. I. Abdul‐Jalil K. M. Sheehan J. Kehoe R. Cummins A. O’Grady D. A. McNamara J. Deasy O. Breathnach L. Grogan B. D. P. O’Neill C. Faul I. Parker E. W. Kay B. T. Hennessy P. Gillen | 2014 | Colorectal Dis2014，，1： | 2 |
| 12 | Methods in cardiomyocyte isolation, culture, and gene transfer显示文摘 | William E. Louch Katherine A. Sheehan Beata M. Wolska | 2011 | Journal of Molecular and Cellular Cardiology2011，，： | 2 |
| 13 | Community-acquired Klebsiella pneumoniae liver abscess: an emerging infection in Ireland and Europe显示文摘 | R. Moore D. O’Shea T. Geoghegan P. W. G. Mallon G. Sheehan | 2013 | Infection2013，，3： | 2 |
| 14 | Comparison of oncostatin M expression in keratoacanthoma and squamous cell carcinoma显示文摘 | Tran TA Ross JS Sheehan CE | 2000 | Mod Pathol2000，13，4： | 2 |
| 15 | 可调互啮合间隙密炼机显示文摘一些切向型改型密炼机自19世纪末就一直用于橡胶胶料的混炼。1916年以前,有许多种设计的密炼机出现和消失,但没有任何一种设计被证明是最好的。橡胶混炼技术的真正突破是在1916年和随后的一些年代。 1916年前,密炼机由两个装在密闭混合室内的切向转子组成,仅有一个开口用于材料的装填和卸料,开口用一盖关闭。1916年和随后的一段时间里,提出了一些专利。 | Edward sheehan Luigi pomini 王焱风 | 1998 | 橡胶参考资料1998，28，2： | 2 |
| 16 | 太原市和纽约市汽车排出颗粒物表面特征比较显示文摘采用扫描电镜和X射线能谱分析仪对太原市和纽约市两地汽车排出颗粒物的表面15种元素含量和形态特征进行观察比较。结果显示,两市汽车排放的颗粒物其表面所含主要元素不同,太原市含Pb高,平均占22.5%,而纽约市则以Fe和Si元素为主,二者约占45%。太原市排放的颗粒物粒径大于纽约市;≤2μm的粒子,太原市占62%,纽约市占76%。两市颗粒物形态基本相似,多数颗粒物表面粗糙、多孔,形态不规则。 | 杨文敏 Christine Sheehan | 1997 | 中国公共卫生1997，13，7： | 2 |
| 17 | Nanobeam mechanics: Elasticity, strength, and toughness of nanorods and nanotubes显示文摘 | Sheehan P E Lieber C M | 1997 | Science1997，，277： | 1 |
| 18 | Negative-ion plasma sources显示文摘 | Rynn N | 1988 | Rev Sci Instrum1988，59，： | 1 |
| 19 | Stereotactic radiosurgery for pituitary adenomas:a review of the 6teratur显示文摘 | Laws ER Sheehan JP Sheehan JM | 2004 | J Neuroonc2004，69，： | 1 |
| 20 | PPAR gamma coactivator-l alpha expression during thyroid hormone and contractile activity-induced mitochondrial adaptations显示文摘 | Irrcher I Adhihetty PJ Sheehan T | 2003 | Am J Physiol Cell Physiol2003，284，： | 1 |
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