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| 1 | Broadband achromatic metalens in terahertz regime显示文摘Achromatic focusing is essential for broadband operation, which has recently been realised from visible to infrared wavelengths using a metasurface. Similarly, multi-terahertz functional devices can be encoded in a desired metasurface phase profile. However, metalenses suffer from larger chromatic aberrations because of the intrinsic dispersion of each unit element. Here, we propose an achromatic metalens with C-shaped unit elements working from 0.3 to 0.8 THz with a bandwidth of approximately 91% over the centre frequency. The designed metalens possesses a high working efficiency of more than 68% at the peak and a relatively high numerical aperture of 0.385. We further demonstrate the robustness of our Cshaped metalens, considering lateral shape deformations and deviations in the etching depth. Our metalens design opens an avenue for future applications of terahertz meta-devices in spectroscopy, time-offlight tomography and hyperspectral imaging systems. | Qingqing Cheng Meilin Ma Dong Yu Zhixiong Shen Jingya Xie Juncheng Wang Nianxi Xu Hanming Guo Wei Hu Shuming Wang Tao Li Songlin Zhuang | 2019 | Science Bulletin2019，64，20： | 16 |
| 2 | Assessing the global averaged sea-level budget from 2003 to 2010显示文摘A global mass balance(Greenland and Antarctica ice sheet mass loss,terrestrial water storage)and different sea-level components(observed sea-level from satellite altimetry,steric sea-level from Ishii data,and ocean mass from gravity recovery and climate experiment,GRACE)are estimated,in terms of seasonal and interannual variabilities from 2003 to 2010.The results show that a detailed analysis of the GRACE time series over the time period 2003–2010 unambiguously reveals an increase in mass loss from the Greenland ice sheet and Antarctica ice sheet.The mass loss of both ice sheets accelerated at a rate of(392.8±70.0)Gt/a during 2003–2010,which contributed(1.09±0.19)mm/a to the global mean sea-level during this time.The net terrestrial water storage(TWS)trend was negative over the 8 a time span,which gave a small positive contribution of(0.25±0.12)mm/a.The interannual variability of the global mean sea-level was at least partly caused by year-to-year variability of land water storage.Estimating GRACE-based ice sheet mass balance and terrestrial water storage by using published estimates for melting glaciers,the results further show that the ocean mass increase since 2003 has resulted half from an enhanced contribution of the polar ice sheets,and half from the combined ice sheet and terrestrial water storage loss.Taking also into account the melting of mountain glaciers(0.41 mm/a)and the small GRACE-based contribution from continental waters(0.25 mm/a),a total ocean mass contribution of(1.75±0.57)mm/a from 2003 to 2010 is found.Such a value represented 75%of the altimetry-based rate of sea-level rise over that period.The contributions to steric sea-level(i.e.,ocean thermal expansion plus salinity effects)are estimated from:(1)the difference between altimetry-based sea-level and ocean mass change and(2)the latest Ishii data.The inferred steric sea-level rate from(1)(1.41 mm/a from 2003 to 2010)did not agree well with the Ishii-based value also estimated here(0.44 mm/a from 2003 to 2010),but phase.The cause for such a discrepancy is not yet known but may be related to inadequate sampling of in situ ocean temperature and salinity measurements. | LI Juan ZUO Juncheng CHEN Meixiang TAN Wei YANG Yiqiu | 2013 | Acta Oceanologica Sinica2013，32，10： | 6 |
| 3 | Serum semaphorin 4C as a diagnostic biomarker in breast cancer:A multicenter retrospective study显示文摘Background:To date,there is no approved blood-based biomarker for breast cancer detection.Herein,we aimed to assess semaphorin 4C(SEMA4C),a pivotal protein involved in breast cancer progression,as a serum diagnostic biomarker.Methods:We included 6,213 consecutive inpatients from Tongji Hospital,Qilu Hospital,and Hubei Cancer Hospital.Training cohort and two validation cohorts were introduced for diagnostic exploration and validation.A pan-cancer cohort was used to independently explore the diagnostic potential of SEMA4C among solid tumors.Breast cancer patients who underwent mass excision prior to modified radical mastectomy were also analyzed.We hypothesized that increased pretreatment serum SEMA4C levels,measured using optimized in-house enzymelinked immunosorbent assay kits,could detect breast cancer.The endpoints were diagnostic performance,including area under the receiver operating characteristic curve(AUC),sensitivity,and specificity.Post-surgery pathological diagnosis was the reference standard and breast cancer staging followed the TNM classification.There was no restriction on disease stage for eligibilities.Results:We included 2667 inpatients with breast lesions,2378 patients with other solid tumors,and 1168 healthy participants.Specifically,118 patients with breast cancer were diagnosed with stage 0(5.71%),620 with stage I(30.00%),966 with stage II(46.73%),217 with stage III(10.50%),and 8 with stage IV(0.39%).Patients with breast cancer had significantly higher serum SEMA4C levels than benign breast tumor patients and normal controls(P<0.001).Elevated serum SEMA4C levels had AUC of 0.920(95%confidence interval[CI]:0.900–0.941)and 0.932(95%CI:0.911–0.953)for breast cancer detection in the two validation cohorts.The AUCs for detecting early-stage breast cancer(n=366)and ductal carcinoma in situ(n=85)were 0.931(95%CI:0.916–0.946)and 0.879(95%CI:0.832–0.925),respectively.Serum SEMA4C levels significantly decreased after surgery,and the reduction was more striking after modified radical mastectomy,compared with mass excision(P<0.001).The positive rate of enhanced serum SEMA4C levels was 84.77%for breast cancer and below 20.75%for the other 14 solid tumors.Conclusions:Serum SEMA4C demonstrated promising potential as a candidate biomarker for breast cancer diagnosis.However,validation in prospective settings and by other study groups is warranted. | Ya Wang Long Qiao Jie Yang Xiong Li Yaqi Duan Jiahao Liu Shaoqi Chen Huayi Li Dan Liu Tian Fang Jingjing Ma Xiaoting Li Fei Ye Junxiang Wan Juncheng Wei Qin Xu Ensong Guo Ping Jin Mingfu Wu Lin Zhang Yun Xia Yaqun Wu Jun Shao Yaojun Feng Qing Zhang Zongyuan Yang Gang Chen Qinghua Zhang Xingrui Li Shixuan Wang Junbo Hu Xiaoyun Wang Mona P.Tan Kazuaki Takabe Beihua Kong Qifeng Yang Ding Ma Qinglei Gao | 2021 | Cancer Communications2021，41，12： | 3 |
| 4 | Association of assisted reproductive technology, germline de novo mutations and congenital heart defects in a prospective birth cohort study显示文摘Emerging evidence suggests that children conceived through assisted reproductive technology(ART)have a higher risk of congenital heart defects(CHDs)even when there is no family history.De novo mutation(DNM)is a well-known cause of sporadic congenital diseases;however,whether ART procedures increase the number of germline DNM(gDNM)has not yet been well studied.Here,we performed whole-genome sequencing of 1137 individuals from 160 families conceived through ART and 205 families conceived spontaneously.Children conceived via ART carried 4.59 more gDNMs than children conceived spontaneously,including 332 paternal and 1.26 maternal DNMs,after correcting for parental age at conception,cigarette smoking,alcohol drinking,and exercise behaviors.Paternal DNMs in offspring conceived via ART are characterized by C>T substitutions at CpG sites,which potentially affect protein-coding genes and are significantly associated with the increased risk of CHD.In addition,the accumulation of non-coding functional mutations was independently associated with CHD and 87.9% of the mutations were originated from the father.Among ART offspring,infertility of the father was associated with elevated paternal DNMs;usage of both recombinant and urinary follicle-stimulating hormone and high-dosage human chorionic gonadotropin trigger was associated with an increase of maternal DNMs.In sum,the increased gDNMs in offspring conceived by ART were primarily originated from fathers,indicating that ART itself may not be a major reason for the accumulation of gDNMs.Our findings emphasize the importance of evaluating the germline status of the fathers in families with the use of ART. | Cheng Wang Hong Lv Xiufeng Ling Hong Li Feiyang Diao Juncheng Dai Jiangbo Du Ting Chen Qi Xi Yang Zhao Kun Zhou Bo Xu Xiumei Han Xiaoyu Liu Meijuan Peng Congcong Chen Shiyao Tao Lei Huang Cong Liu Mingyang Wen Yangqian Jiang Tao Jiang Chuncheng Lu Wei Wu Di Wu Minjian Chen Yuan Lin Xuejiang Guo Ran Huo Jiayin Liu Hongxia Ma Guangfu Jin Yankai Xia Jiahao Sha Hongbing Shen Zhibin Hu | 2021 | Cell Research2021，31，8： | 2 |
| 5 | Solubilities of diglycolic acid esters at temperatures ranging from (343 to 363 ) K in supercritical carbon dioxide 显示文摘 | Wang Wei Yang Haijian Hu Juncheng | 2010 | J Chem Eng Data2010，55，2： | 1 |
| 6 | Fiber temperature sensor for high-pressure environment 显示文摘 | Huang Zhengyu Peng Wei Xu Juncheng | 2005 | Optical Engineering2005，44，10： | 1 |
| 7 | On De Giorgi's conjecture: Recent progress and open problems显示文摘In 1979,De Giorgi conjectured that the only bounded monotone solutions to the Allen-Cahn equation △u+u-u^3=0 in R^N,are one-dimensional.This conjecture and its connection with minimal surfaces and Toda systems are the subject of this survey article. | Hardy Chan Juncheng Wei | 2018 | Science China Mathematics2018，61，11： | 1 |
| 8 | Classification of solutions of higher order conformally invariant equations显示文摘 | Juncheng Wei Xingwang Xu | 1999 | Mathematische Annalen1999，，2： | 1 |
| 9 | High-performance self-organized Si nanocomposite anode for lithium-ion batteries显示文摘Silicon is being investigated extensively as an anodic material for next-generation lithium ion batteries for portable energy storage and electric vehicles.However,the large changes in volume during cycling lead to the breakdown of the conductive network in Si anodes and the formation of an unstable solid-electrolyte interface,resulting in capacity fading.Here,we demonstrate nanoparticles with a Si@Mn_(22.6)Si_(5.4)C_4@C double-shell structure and the formation of self-organized Si-Mn-C nanocomposite anodes during the lithiation/delithiation process.The anode consists of amorphous Si particles less than 10 nm in diameter and separated by an interconnected conductive/buffer network,which exhibits excellent charge transfer kinetics and charge/discharge performances.A stable specific capacity of 1100 mAh·g^(-1) at 100 mA·g^(-1) and a coulombic efficiency of 99.2%after 30 cycles are achieved.Additionally,a rate capacity of 343 mAh·g^(-1) and a coulombic efficiency of 99.4%at 12000 mA·g^(-1) are also attainable.Owing to its simplicity and applicability,this strategy for improving electrode performance paves a way for the development of high-performance Si-based anodic materials for lithium ion batteries. | Xiuyun Zhao Dingguo Xia Lin Gu Juncheng Yue Biao Li Hang Wei Huijun Yan Ruqiang Zou Yingxia Wang Xiayan Wang Ze Zhang Jixue Li | 2014 | Journal of Energy Chemistry2014，23，3： | 1 |
| 10 | Overexpression of vimentin contributes to prostate cancer invasion and metastasis via src regulation 显示文摘 | Wei Juncheng Xu Gang Wu Mingfu | 2008 | Anticancer Res2008，28，： | 1 |
| 11 | Ground state of N coupled nonlinear Schr/Sdinger equations in R^n, n ≤ 3 显示文摘 | Lin Taichia Wei Juncheng | 2005 | Comm Math Phys2005，255，3： | 1 |
| 12 | Strongly interacting bumps for the Schrc, dinger-Newton equations显示文摘 | Wei Juncheng Winter M | 2009 | J Math Phys2009，50，1： | 1 |
| 13 | Concentrating solutions for the Hénon equation in ?2显示文摘 | Pierpaolo Esposito Angela Pistoia Juncheng Wei | 2006 | Journal d’Analyse Mathématique2006，，1： | 1 |
| 14 | Genome-wide analysis of GH3 gene family in soybean( Glycine max)显示文摘 | Wei ZHAO Xinjie SHEN Wei GUO Qingbo YOU Yanjie YAO Jianhua LU Juncheng ZHANG Lei HUANG Bingbing DUAN Huarong LV Aili BAO Yongqing JIAO | 2016 | Oil Crop Science2016，1，2： | 1 |
| 15 | Existence and stability of singular patterns in a GinzburgLaudau equation coupled with a mean field显示文摘 | Norbury J Winter M WEI Juncheng | 2002 | Nonlinearity2002，15，： | 1 |
| 16 | A polysaccharide fraction of adlay seed ( Coix lachryma - jobi L.) induces apoptosis in human non-small cell lung cancer A549 cells显示文摘 | Xiangyi Lu Wei Liu Junhua Wu Mengxian Li Juncheng Wang Jihui Wu Cheng Luo | 2012 | Biochemical and Biophysical Research Communications2012，，： | 1 |
| 17 | A novel long-term intravenous combined with local treatment with human amnion-derived mesenchymal stem cells for a multidisciplinary rescued uremic calciphylaxis patient and the underlying mechanism显示文摘Calciphylaxis is a rare disease characterized histologically by microvessel calcification and microthrombosis,with high mortality and no proven therapy.Here,we reported a severe uremic calciphylaxis patient with progressive skin ischemia,large areas of painful malodorous ulcers,and mummified legs.Because of the worsening symptoms and signs refractory to conventional therapies,treatment with human amnion-derived mesenchymal stem cells(hAMSCs)was approved.Preclinical release inspections of hAMSCs,efficacy,and safety assessment,including cytokine secretory ability,immunocompetence,tumorigenicity,and genetics analysis in vitro,were introduced.We further performed acute and long-term hAMSC toxicity evaluations in C57BL/6 mice and rats,abnormal immune response tests in C57BL/6 mice,and tumorigenicity tests in neonatal Balbc-nu nude mice.After the preclinical research,the patient was treated with hAMSCs by intravenous and local intramuscular injection and external supernatant application to the ulcers.When followed up to 15 months,the blood-based markers of bone and mineral metabolism improved,with skin soft tissue regeneration and a more favorable profile of peripheral blood mononuclear cells.Skin biopsy after 1-month treatment showed vascular regeneration with mature noncalcified vessels within the dermis,and 20 months later,the re-epithelialization restored the integrity of the damaged site.No infusion or local treatment-related adverse events occurred.Thus,this novel long-term intravenous combined with local treatment with hAMSCs warrants further investigation as a potential regenerative treatment for uremic calciphylaxis due to effects of inhibiting vascular calcification,stimulating angiogenesis and myogenesis,anti-inflammatory and immune modulation,multidifferentiation,re-epithelialization,and restoration of integrity. | Lianju Qin Jing Zhang Yujie Xiao Kang Liu Yugui Cui Fangyan Xu Wenkai Ren Yanggang Yuan Chunyan Jiang Song Ning Xiaoxue Ye Ming Zeng Hanyang Qian Anning Bian Fan Li Guang Yang Shaowen Tang Zhihong Zhang Juncheng Dai Jing Guo Qiang Wang Bin Sun Yifei Ge Chun Ouyang Xueqiang Xu Jing Wang Yaoyu Huang Hongqing Cui Jing Zhou Meilian Wang Zhonglan Su Yan Lu Di Wu Jingping Shi Wei Liu Li Dong Yinbing Pan Baiqiao Zhao Ying Cui Xueyan Gao Zhanhui Gao Xiang Ma Aiqin Chen Jie Wang Meng Cao Qian Cui Li Chen Feng Chen Youjia Yu Qiang Ji Zhiwei Zhang Mufeng Gu Xiaojun Zhuang Xiaolin Lv Hui Wang Yanyan Pan Ling Wang Xianrong Xu Jing Zhao Xiuqin Wang Cuiping Liu Ningxia Liang Changying Xing Jiayin Liu Ningning Wang | 2022 | Journal of Molecular Cell Biology2022，14，2： | 1 |
| 18 | Crystal structure of human BS69 Bromo-ZnF-PWWP reveals its role in H3K36me3 nucleosome binding显示文摘 | Juncheng Wang Su Qin Fudong Li Sai Li Wei Zhang Junhui Peng Zhiyong Zhang Qingguo Gong Jihui Wu Yunyu Shi | 2014 | Cell Research2014，24，7： | 0 |
| 19 | Analysis of Sea Surface Temperature Cooling in Typhoon Events Passing the Kuroshio Current显示文摘The aim of this study is to investigate the sea surface temperature(SST) cooling as typhoons pass the Kuroshio Current.A numerical circulation model,denoted as the Stony Brook Parallel Ocean Model(sbPOM),was used to simulate the SST,which includes four wave-induced effect terms(i.e.,radiation stress,nonbreaking waves,Stokes drift,and breaking waves) simulated using the third-generation wave model,called WAVEWATCH-Ⅲ(WW3).The significant wave height(SWH) measurements from the Jason-2 altimeter were used to validate the WW3-simulated results,yielding a root mean square error(RMSE) of less than 0.50 m and a correlation coefficient(COR) of approximately 0.93.The water temperature measured from the Advanced Research and Global Observation Satellite was applied to validate the model simulation.Accordingly,the RMSE of the SST is 0.92℃ with a COR of approximately 0.99.As revealed in the sbPOM-simulated SST fields,a reduction in the SST at the Kuroshio Current region was observed as a typhoon passed,although the water temperature of the Kuroshio Current is relatively high.The variation of the SST is consistent with that of the current,whereas the maximum SST lagged behind the occurrence of the peak SWH.Moreover,the Stokes drift plays an important role in the SST cooling after analyzing four wave-induced terms in the background of the Kuroshio Current.The sensitivity experiment also showed that the accuracy of the water temperature was significantly reduced when including breaking waves,which play a negative role in the inside part of the ocean.The variation in the mean mixing layer depth(MLD) showed that a typhoon could enhance the mean MLD in the Kuroshio Current area in September and October,whereas a typhoon has little influence on the mean MLD in the Kuroshio Current area in May.Moreover,the mean MLD rapidly decreased with the weakening of the strong wind force and wave-induced effects when a typhoon crossed the Kuroshio Current. | HU Yuyi SHAO Weizeng SHEN Wei ZUO Juncheng JIANG Tao HU Song | 2024 | Journal of Ocean University of China2024，23，2： | 0 |
| 20 | Applying Normally-off GaN HEMTs for Coreless High-frequency Wireless Chargers显示文摘Wide-bandgap(WBG)devices such as Gallium-Nitride(GaN)High Electron Mobility Transistors(HEMTs)have become popular in the power electronics industry as they offer a lower switching loss,higher thermal capability and higher power density than conventional silicon devices.As an attempt of applying WBG devices to the wireless charging technology,this paper adopts two different types of normally-off GaN HEMTs.One adopts the cascode structure provided by Transphorm Inc,operated under 800kHz to charge a battery pack on an electric scooter at 48 V/500W,with the air gap between the transceiver and receiver of~10cm.The other is enhancement-mode GaN HEMTs provided by GaN Systems Inc,operated at~6MHz to use one transceiver to charge multiple cell phones@~20W.Both of these chargers have no magnetic cores to reduce the cost and weight.Experimental results show both types of GaN HEMTs significantly increased the charging efficiency over conventional Si devices.Challenges of applying such fast-transition devices are discussed,e.g.,common-source inductance and the gate-drive-loop parasitic. | Wei Qian Xi Zhang Yongsheng Fu Juncheng Lu Hua Bai | 2017 | CES Transactions on Electrical Machines and Systems2017，1，4： | 0 |
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