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| 1 | Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock: 2012显示文摘 | R. Phillip Dellinger Mitchell M. Levy Andrew Rhodes Djillali Annane Herwig Gerlach Steven M. Opal Jonathan E. Sevransky Charles L. Sprung Ivor S. Douglas Roman Jaeschke Tiffany M. Osborn Mark E. Nunnally Sean R. Townsend Konrad Reinhart Ruth M. Kleinpell | 2013 | Critical Care Medicine2013，，2： | 12 |
| 2 | PLEIOTROPIC REGULATORY LOCUS 1 (PRL1) Integrates the Regulation of Sugar Responses with Isoprenoid Metabolism in Arabidopsis显示文摘在植物房间的 isoprenoids 的生合成从 mevalonate (MVA ) 在 cytosol 生产的先锋发生小径并且在由 methylerythritol 4 磷酸盐(MEP ) 的质体,小径,而是很少对协调两条小径的机制被知道。在 Arabidopsis thaliana 为如此的协作发信号的糖的重要性的证据被没有变化,在相关 MEP 小径抄本,蛋白质,或酶活动的层次显示出导出 MEP 的 isoprenoid 产品(叶绿素和类胡萝卜素) 的增加的累积的异种的描述这里提供。这异种被发现是新 loss-of-function 等位基因 PRL1 (多种的规章的地点 1 ) ,编码作为糖的一个全球管理者工作的保存 WD 蛋白质的基因,应力,和荷尔蒙回答,部分地由 SNF1 相关的蛋白质 kinases (SnRK1 ) 的抑制。与在 MVA 小径的主要的规章的酶的 phosphorylation 和 inactivation 的 SnRK1 kinases 的报导角色一致(hydroxymethylglutaryl 辅酶 -- reductase ) ,它的活动或蛋白质层次在 prl1 幼苗被减少。然而,导出 MVA 的结束产品(甾醇) 的累积在变异的幼苗是未改变的。蔗糖补充到野类型的幼苗 phenocopied prl1 变化以 isoprenoid 新陈代谢,建议观察 isoprenoid 显型从增加的糖累积导致 prl1 异种。在摘要, PRL1 看起来与糖,荷尔蒙,和压力回答协调 isoprenoid 新陈代谢。 | Ursula Flores-Perez Jordi Perez-Gil Marta Closa Louwrance R Wright Patricia Botella-Pavia Michael A. Phillips Albert Ferrer Jonathan Gershenzon Manuel Rodriguez-Concepcion | 2010 | Molecular Plant2010，3，1： | 5 |
| 3 | Pushing the boundaries of diode-pumped solid-state lasers for high-energy applications显示文摘We report on the successful demonstration of a 150 J nanosecond pulsed cryogenic gas cooled,diode-pumped multi-slab Yb:YAG laser operating at 1 Hz.To the best of our knowledge,this is the highest energy ever recorded for a diodepumped laser system. | Saumyabrata Banerjee Paul Mason Jonathan Phillips Jodie Smith Thomas Butcher Jacob Spear Mariastefania De Vido Gary Quinn Danielle Clarke Klaus Ertel Cristina Hernez-Gomez Chris Edwards John Collier | 2020 | High Power Laser Science and Engineering2020，8，2： | 4 |
| 4 | Predisposing factors for positive D-Xylose breath test for evaluation of small intestinal bacterial overgrowth:A retrospective study of 932 patients显示文摘AIM: To investigate, in the largest cohort to date, patient characteristics and associated risk factors for developing small intestinal bacterial overgrowth(SIBO) using the D-Xylose breath test(XBT).METHODS: We performed a retrospective crosssectional study to analyze patient characteristics who underwent the XBT for evaluation of SIBO. Diagnostic testing with the XBT was performed based on a clinical suspicion for SIBO in patients with symptoms of bloating, abdominal pain, abdominal distension, weight loss, diarrhea, and/or constipation. Consecutive electronicmedical records of 932 patients who completed the XBT at the University of Florida between 2005 and 2009 were reviewed. A two-way Analysis of Variance(ANOVA) was used to test for several associations including age, gender, and body mass index(BMI) with a +XBT. A two-way ANOVA was also performed to control for the differences and interaction with age and between genders. A similar analysis was repeated for BMI. Associations between medical conditions and prior surgical histories were conducted using the Mantel-Haenszel method for 2 by 2 contingency tables, stratified for gender. Reported odds ratio estimates reflect the odds of the prevalence of a condition within the +XBT group to that of the-XBT group. P values of less than 0.05(two-sided) were considered statistically significant.RESULTS: In the 932 consecutive eligible subjects studied, 513 had a positive XBT. A positive association was found between female gender and a positive XBT(P = 0.0025), and females with a positive test were, on average, greater than 5 years older than those with a negative test(P = 0.024). The mean BMI of positive XBT subjects was normal(24.5) and significantly lower than the subjects with a negative XBT(29.5)(P = 0.0050). A positive XBT was associated with gastroesophageal reflux disease(GERD)(OR = 1.35; 95%CI: 1.02-1.80, P = 0.04), peptic ulcer disease(PUD)(OR = 2.61; 95%CI: 1.48-4.59, P < 0.01), gastroparesis(GP)(OR = 2.04; 95%CI: 1.21-3.41, P < 0.01) and steroid use(OR = 1.35; 95%CI: 1.02-1.80, P = 0.01). Irritable bowel syndrome, independent protonpump inhibitor(PPI) usage, or previous abdominal surgery was not significantly associated with a positive XBT. No single subdivision by gender or PPI use was associated with a significant difference in the odds ratios between any of the subsets. CONCLUSION: Female gender, lower BMI, steroid use, PUD, GERD(independent of PPI use), and GP were more prevalent in patients with SIBO, determined by a positive XBT. Increasing age was associated with SIBO in females, but not in males. | Richard A Schatz Qing Zhang Nilesh Lodhia Jonathan Shuster Phillip P Toskes Baharak Moshiree | 2015 | World Journal of Gastroenterology2015，21，15： | 4 |
| 5 | Development of a 100 J,10 Hz laser for compression experiments at the High Energy Density instrument at the European XFEL显示文摘In this paper we review the design and development of a 100 J, 10 Hz nanosecond pulsed laser, codenamed DiPOLE100 X,being built at the Central Laser Facility(CLF). This 1 kW average power diode-pumped solid-state laser(DPSSL) is based on a master oscillator power amplifier(MOPA) design, which includes two cryogenic gas cooled amplifier stages based on DiPOLE multi-slab ceramic Yb:YAG amplifier technology developed at the CLF. The laser will produce pulses between 2 and 15 ns in duration with precise, arbitrarily selectable shapes, at pulse repetition rates up to 10 Hz, allowing real-time shape optimization for compression experiments. Once completed, the laser will be delivered to the European X-ray Free Electron Laser(XFEL) facility in Germany as a UK-funded contribution in kind, where it will be used to study extreme states of matter at the High Energy Density(HED) instrument. | Paul Mason Saumyabrata Banerjee Jodie Smith Thomas Butcher Jonathan Phillips Hauke Hoppner Dominik Moller Klaus Ertel Mariastefania De Vido Ian Hollingham ANDrew Norton Stephanie Tomlinson Tinesimba Zata Jorge Suarez Merchan Chris Hooker Mike Tyldesley Toma Toncian Cristina HernANDez-Gomez Chris Edwards John Collier | 2018 | High Power Laser Science and Engineering2018，6，4： | 4 |
| 6 | Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock显示文摘 | R. Phillip Dellinger Jean M. Carlet Henry Masur Herwig Gerlach Thierry Calandra Jonathan Cohen Juan Gea-Banacloche Didier Keh John C. Marshall Margaret M. Parker Graham Ramsay Janice L. Zimmerman Jean-Louis Vincent M. M. Levy | 2004 | Intensive Care Medicine2004，，4： | 3 |
| 7 | Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock显示文摘 | R. Phillip Dellinger Jean M. Carlet Henry Masur Herwig Gerlach Thierry Calandra Jonathan Cohen Juan Gea-Banacloche Didier Keh John C. Marshall Margaret M. Parker Graham Ramsay Janice L. Zimmerman Jean-Louis Vincent Mitchell M. Levy | 2004 | Critical Care Medicine2004，，3： | 2 |
| 8 | China's balance of emissions embodied in trade: approaches to measurement and allocating international responsibility显示文摘 | Jiahua Pan Jonathan Phillips Ying Chen | 2008 | Oxford Review of Economic Policy2008，，2： | 2 |
| 9 | Growth inhibition of pancreatic cancer cells by histone deacetylase inhibitor belinostat through suppression of multiple pathways including HIF, NFkB, and mTOR signaling in vitro and in vivo显示文摘 | Wenwen Chien Dhong Hyun Lee Yun Zheng Peer Wuensche Rosie Alvarez Ding Ling Wen Ahmed M. Aribi Su Ming Thean Ngan B. Doan Jonathan W. Said H. Phillip Koeffler | 2014 | Mol. Carcinog2014，，9： | 1 |
| 10 | Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock: 2012显示文摘 | R. Phillip Dellinger Mitchell M. Levy Andrew Rhodes Djillali Annane Herwig Gerlach Steven M. Opal Jonathan E. Sevransky Charles L. Sprung Ivor S. Douglas Roman Jaeschke Tiffany M. Osborn Mark E. Nunnally Sean R. Townsend Konrad Reinhart Ruth M. Kleinpell | 2013 | Critical Care Medicine2013，，2： | 1 |
| 11 | China's Balance of Emissions Embodied in Trade:Approaches to Measurement and Allocating International Responsibility 显示文摘 | Jiahua Pan Jonathan Phillips Ying Chen | 2008 | Oxford Review of Economic Policy2008，，2： | 1 |
| 12 | Prognostic G leason grade grouping: data based on the modified G leason scoring system显示文摘 | Phillip M. Pierorazio Patrick C. Walsh Alan W. Partin Jonathan I. Epstein | 2013 | BJU Int2013，，5： | 1 |
| 13 | Erosion, isostatic response, and the missing peneplains显示文摘 | Jonathan D Phillips | 2002 | Geomorphology2002，45，34： | 1 |
| 14 | Bidirectional transepithelial water transport: measurement and governing mechanisms显示文摘 | Phillips LB Donovan B | 1999 | Biophys J1999，76，2： | 1 |
| 15 | China's balance of emissions embodied in trade:approaches to measurement and allocating international responsibility显示文摘 | Pan Jiahua Phillips Jonathan Chen Ying | 2008 | Oxford Review of Economic Policy2008，，24： | 1 |
| 16 | Aflatoxin and PAH exposure biomarkers in a U.S. population with a high incidence of hepatocellular carcinoma显示文摘 | Natalie M. Johnson Guoqing Qian Li Xu Danielle Tietze Alicia Marroquin-Cardona Abraham Robinson Melanie Rodriguez Linda Kaufman Kyle Cunningham James Wittmer Fernando Guerra Kirby C. Donnelly Jonathan H. Williams Jia-Sheng Wang Timothy D. Phillips | 2010 | Science of the Total Environment2010，，23： | 1 |
| 17 | An evaluation of the factors determining the effectiveness of water quality buffer zones显示文摘 | PHILLIPS JONATHAN D | 1989 | Journal of Hydrology1989，107，： | 1 |
| 18 | The Radiographic Anatomy of the Thoracic Pedicle显示文摘 | Jonathan H. Phillips Thomas F. Kling Mervyn D. Cohen | 1994 | Spine ( Suppl)1994，，4： | 1 |
| 19 | Determinants of aflatoxin levels in Ghanaians: Sociodemographic factors, knowledge of aflatoxin and food handling and consumption practices显示文摘 | Pauline Jolly Yi Jiang William Ellis Richard Awuah Obinna Nnedu Timothy Phillips Jia-Sheng Wang Evans Afriyie-Gyawu Lili Tang Sharina Person Jonathan Williams Curtis Jolly | 2006 | International Journal of Hygiene and Environmental Health2006，，4： | 1 |
| 20 | Measuring complexity of environmental gradients显示文摘 | Jonathan D. Phillips | 1986 | Vegetatio (-)1986，，2： | 1 |
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