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| 1 | Mesh implants: An overview of crucial mesh parameters显示文摘Hernia repair is one of the most frequently performed surgical interventions that use mesh implants. This article evaluates crucial mesh parameters to facilitate selection of the most appropriate mesh implant, considering raw materials, mesh composition, structure parameters and mechanical parameters. A literature review was performed using the Pub Med database. The most important mesh parameters in the selection of a mesh implant are the raw material, structural parameters and mechanical parameters, which should match the physiological conditions. The structural parameters, especially the porosity, are the most important predictors of the biocompatibility performance of synthetic meshes. Meshes with large pores exhibit less inflammatory infiltrate, connective tissue and scar bridging, which allows increased soft tissue ingrowth. The raw material and combination of raw materials of the used mesh, including potential coatings and textile design, strongly impact the inflammatory reaction to the mesh. Synthetic meshes made from innovative polymers combined with surface coating have been demonstrated to exhibit advantageous behavior in specialized fields. Monofilament, largepore synthetic meshes exhibit advantages. The value of mesh classification based on mesh weight seems to be overestimated. Mechanical properties of meshes, such as anisotropy/isotropy, elasticity and tensile strength, are crucial parameters for predicting mesh performance after implantation. | Lei-Ming Zhu Philipp Schuster Uwe Klinge | 2015 | World Journal of Gastrointestinal Surgery2015，7，10： | 9 |
| 2 | Recent trends in liver transplantation for alcoholic liver disease in the United States显示文摘AIM To examine temporal changes in the indications for liver transplantation(LT) and characteristics of patients transplanted for alcoholic liver disease(ALD).METHODS We performed a retrospective cohort analysis of trends in the indication for LT using the United Network for Organ Sharing(UNOS) database between 2002 and 2015. Patients were grouped by etiology of the liver disease and characteristics were compared using χ~2 and t-tests. Time series analysis was used identifying any year with a significant change in the number of transplants per year for ALD, and before and after eras were modeled using a general linear model. Subgroup analysis of recipients with ALD was performed by age group, gender, UNOS region and etiology(alcoholic cirrhosis, alcoholic hepatitis and hepatitis C-alcoholic cirrhosis dual listing).RESULTS Of 74216 liver transplant recipients, ALD(n = 9400, 12.7%) was the third leading indication for transplant after hepatitis C and hepatocellular carcinoma. Transplants for ALD, increased from 12.8%(553) in 2002 to 16.5%(1020) in 2015. Time series analysis indicated a significant increase in the number of transplants per year for ALD in 2013(P = 0.03). There were a stable number of transplants per year between 2002 and 2012(linear coefficient 3, 95%CI:-4.6, 11.2) an increase of 177 per year between 2013 and 2015(95%CI: 119, 234). This increase was significant for all age groups except those 71-83 years old, was observed for both genders, and was incompletely explained by a decrease in transplants for hepatitis C and ALD dual listing. All UNOS regions except region 9 saw an increase in the mean number of transplants per year when comparing eras, and this increase was significant in regions 2, 3, 4, 5, 6, 8, 10 and 11.CONCLUSION There has been a dramatic increase in the number of transplants for ALD starting in 2013. | Catherine E Kling James D Perkins Robert L Carithers Dennis M Donovan Lena Sibulesky | 2017 | World Journal of Hepatology2017，9，36： | 6 |
| 3 | Design and analysis of stiffened composite panels including post-buckling and collapse显示文摘 | R. Degenhardt A. Kling K. Rohwer A.C. Orifici R.S. Thomson | 2007 | Computers and Structures2007，，9： | 3 |
| 4 | Chinese institutional investors’ sentiment显示文摘 | Gerhard Kling Lei Gao | 2007 | Journal of International Financial Markets Institutions & Money2007，，4： | 2 |
| 5 | 术前检测患者血液中总蛋白、白蛋白与白细胞介素-1受体拮抗剂作为切口疝修补术后是否出现血清肿的预测指标显示文摘患者切口疝修补术后出现血清肿是非常常见的,约占20%~30%,其中10%的患者渗液量超过50ml。出现血清肿并不一定出现并发症,但血清肿患者术后容易出现疼痛不适,尤其是补片感染导致修补手术失败,切口疝复发。对某些患者及时使用细针抽液,甚至是手术治疗都是必要的。 | Klink CD Binnebosel M Lucas AH Schachtrupp A Grommes J Conze J Klinge U Neumann U Junge K 宗振(译) 陈双(校) | 2012 | 中华疝和腹壁外科杂志(电子版)2012，6，2： | 2 |
| 6 | Host Remodeling of the Gut Microbiome and Metabolic Changes during Pregnancy显示文摘 | Omry Koren Julia K. Goodrich Tyler C. Cullender Aymé Spor Kirsi Laitinen Helene Kling B?ckhed Antonio Gonzalez Jeffrey J. Werner Largus T. Angenent Rob Knight Fredrik B?ckhed Erika Isolauri Seppo Salminen Ruth E. Ley | 2012 | Cell2012，，3： | 2 |
| 7 | Preoperative acute hype-rvolemic hemodilution with hyolroxyethylstarch:an alternative to acute normovolemic hemodilution显示文摘 | Mielke LL Entholzner EK Kling M | 1997 | Anesth Analg1997，84，： | 1 |
| 8 | Interaction between Electrical Arc and Nd: YAG Laser Radiation显示文摘 | Stute U Kling R Hermsdorf J | 2007 | Annals of the CIRP2007，56，1： | 1 |
| 9 | Altered collagen syntheses in fascia transversalis of patients with inguinal hernia显示文摘 | ] Klinge U Zheng H Si ZY | 1999 | Hernia1999，3，4： | 1 |
| 10 | Incisional hernia:open techniques显示文摘 | Klinge U Conze J Krones CJ | 2005 | World J Surg2005，29，9： | 1 |
| 11 | Pathophysiology of the abdominal wall显示文摘 | Klinge U Conze J Limberg W | 1996 | Chirurg1996，67，3： | 1 |
| 12 | Molecular characterization of two strains of the avian adeno-associated virus (AAAV) 显示文摘 | Hess M Paul G Kling S | 1995 | Arch Virol1995，140，： | 1 |
| 13 | Two-year outcome after recurrent implantation failure prognostic factors and additional interventions 显示文摘 | Kling C Schmutzler A Wilke G | 2008 | Arch Gynecol Obstet2008，278，2： | 1 |
| 14 | Carbon dioxidesupersaturation in the surface waters of lakes 显示文摘 | Cole J J Caraco F N Kling W G | 1994 | Science1994，265，5178： | 1 |
| 15 | Cerebrovascular atherosclerosis correlates with Alzheimer pathology in neurodegenerative dementias 显示文摘 | Yarchoan M Xie SX Kling MA | 2012 | Brain2012，135，12： | 1 |
| 16 | Con trasting cardiac regional responses o A-type and B-type natri- uretic peptide to experimental chronic heart failure显示文摘 | HYSTAD M E KLINGE R SPURKLAND A | 2000 | Scand J Clin Lab Invest2000，60，4： | 1 |
| 17 | PVDF as a new polymer for the construction of surgical meshes 显示文摘 | KLINGE U KLOSTERHALFEN B OTTINGER AP | 2002 | Biomaterials2002，23，16： | 1 |
| 18 | Thermodynamical properties of a rotating ideal Bose gasE显示文摘 | Kling S Pelster A | 2007 | Physical Review A2007，76，02： | 1 |
| 19 | The lightweight and large porous mesh concept for hernia repair显示文摘 | Klosterhalfen B Jange K Klinge U | 2005 | Expert Rev Med Devices2005，2，1： | 1 |
| 20 | Multiplicity of cerebrospinal fluid functions: New challenges in health and disease 显示文摘 | Johanson CE Duncan JA 3rd Klinge PM | 2008 | Cerebrospinal Fluid Res2008，5，： | 1 |
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