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| 1 | 肛裂临床诊治指南(第三次修订)显示文摘“美国结直肠外科医师协会(American Societyof ColonandRectal Surgeons.ASCRS)”(协会)致力于推进结直肠和肛门疾病的相关理论以及预防和诊疗水平的提高,给患者提供优质的医疗服务。“标准委员会”由协会中在结直肠外科方面有显著专长的成员组成。该委员会的建立是为了引领国际结直肠和肛门疾病诊治的发展,以建立具有循证医学证据的临床诊疗指南。指南是涵盖性的,非指令性的,目的是为临床决策提供信息,而非具体的治疗方法。指南适用于所有相关的医护人员以及希望得到相应指南中疾病的相关诊治信息的患者。 | Farshid Araghizadeh ~ Robin Boushey Sridhar Chalasani George Chang Robert Cima Gary Dunn Daniel Feingold Philip Fleshner Daniel Geisler Jill Genua Sharon Gregorcyk Daniel Herzig Andreas Kaiser Ravin Kumar David Larson Steven Mills John Monson P. Terry Phang Feza Remzi David Rivadeneira Howard Ross Peter Senatore Elin Sigurdson Thomas Stahl Scott Steele Scott Strong Charles Tement Judith Trudel Madhulika Varnna Martin Weiser 丁义江(译) 皇甫少华(译) 丁曙晴(译) | 2013 | 中华胃肠外科杂志2013，16，7： | 70 |
| 2 | Direct reprogramming of human fibroblasts into dopaminergic neuron-like cells显示文摘外长的 dopaminergic 神经原(DA 神经原) 的移植是为治疗 Parkinson 的疾病(PD ) 的一条有希望的途径。然而,主要跌倒块是施主 DA 神经原的可靠来源的缺乏。这里,我们证明五 transcriptional 因素 Mash1, Ngn2, Sox2, Nurr1,和 Pitx3 的联合直接并且有效地装改编人成纤维细胞进 DA 像神经原的房间。为为 DA 神经原的各种各样的标记积极的染色的 reprogrammed 房间。他们也显示出典型 DA 举起和生产性质。而且,他们展出了 DA 神经原特定的 electrophysiological 侧面。最后,他们在一个老鼠 PD 模型提供了征兆的地势。因此,我们的直接 reprogrammed DA 像神经原的房间是为 PD 的房间代替治疗的有希望的来源。 | Xinjian Liu Fang Li Elizabeth A Stubblefield Barbara Blanchard Toni L Richards Gaynor A Larson Yujun He Qian Huang Aik-Choon Tan Dabing Zhang Timothy A Benke John R Sladek Nancy R Zahniser Chuan-Yuan Li | 2012 | Cell Research2012，22，2： | 14 |
| 3 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 4 | The Origin and Evolution of Mutations in Acute Myeloid Leukemia显示文摘 | John S. Welch Timothy J. Ley Daniel C. Link Christopher A. Miller David E. Larson Daniel C. Koboldt Lukas D. Wartman Tamara L. Lamprecht Fulu Liu Jun Xia Cyriac Kandoth Robert S. Fulton Michael D. McLellan David J. Dooling John W. Wallis Ken Chen Christop | 2012 | Cell2012，，2： | 3 |
| 5 | Advantages of fast-track recovery after laparoscopic right hemicolectomy for colon cancer显示文摘 | Vassiliki L. Tsikitis Stefan D. Holubar Eric J. Dozois Robert R. Cima John H. Pemberton David W. Larson | 2010 | Surgical Endoscopy2010，，8： | 3 |
| 6 | Hand-assisted laparoscopic colon and rectal cancer surgery: Feasibility, short-term, and oncological outcomes显示文摘 | Rajesh Pendlimari Stefan D. Holubar Jirawat Pattan-Arun David W. Larson Eric J. Dozois John H. Pemberton Robert R. Cima | 2010 | Surgery2010，，2： | 2 |
| 7 | Review of 1027 Patients With Newly Diagnosed Multiple Myeloma显示文摘 | Robert A. Kyle Morie A. Gertz Thomas E. Witzig John A. Lust Martha Q. Lacy Angela Dispenzieri Rafael Fonseca S. Vincent Rajkumar Janice R. Offord Dirk R. Larson Matthew E. Plevak Terry M. Therneau Philip R. Greipp | 2003 | Mayo Clinic Proceedings2003，，1： | 2 |
| 8 | Enterocutaneous fistula: Are treatments improving?显示文摘 | John M. Draus Sara A. Huss Niall J. Harty William G. Cheadle Gerald M. Larson | 2006 | Surgery2006，，4： | 1 |
| 9 | The Origin and Evolution of Mutations in Acute Myeloid Leukemia显示文摘 | John S. Welch Timothy J. Ley Daniel C. Link Christopher A. Miller David E. Larson Daniel C. Koboldt Lukas D. Wartman Tamara L. Lamprecht Fulu Liu Jun Xia Cyriac Kandoth Robert S. Fulton Michael D. McLellan David J. Dooling John W. Wallis Ken Chen Christop | 2012 | Cell2012，，2： | 1 |
| 10 | Initiation of Allopurinol at First Medical Contact for Acute Attacks of Gout: A Randomized Clinical Trial显示文摘 | Thomas H. Taylor John N. Mecchella Robin J. Larson Kevin D. Kerin Todd A. MacKenzie | 2012 | The American Journal of Medicine2012，，11： | 1 |
| 11 | Anatomy of the perineal membrane as seen in magnetic resonance images of nulliparous women显示文摘 | Catherine J. Brandon Christina Lewicky-Gaupp Kindra A. Larson John O.L. DeLancey | 2009 | American Journal of Obstetrics and Gynecology2009，，5： | 1 |
| 12 | Phase I pharmacokinetic and biodistribution study with escalating doses of 223 Ra-dichloride in men with castration-resistant metastatic prostate cancer显示文摘 | Jorge A. Carrasquillo Joseph A. O’Donoghue Neeta Pandit-Taskar John L. Humm Dana E. Rathkopf Susan F. Slovin Matthew J. Williamson Kristine Lacuna Anne-Kirsti Aksnes Steven M. Larson Howard I. Scher Michael J. Morris | 2013 | European Journal of Nuclear Medicine and Molecular Imaging2013，，9： | 1 |
| 13 | Effect of Infliximab on Short-Term Complications in Patients Undergoing Operation for Chronic Ulcerative Colitis显示文摘 | Chelliah R. Selvasekar Robert R. Cima David W. Larson Eric J. Dozois Jeffrey R. Harrington William S. Harmsen Edward V. Loftus William J. Sandborn Bruce G. Wolff John H. Pemberton | 2007 | Journal of the American College of Surgeons2007，，5： | 1 |
| 14 | The highly conserved cardiac glycoside binding site of Na, K - AT- Pase plays a role in blood pressure regulation 显示文摘 | Iva Dostanic - Larson James W Van Huysse John N Lorenz | 2005 | PNAS2005，102，15： | 1 |
| 15 | A commercially vilable synthesis of cyanotrimethylsilane显示文摘 | GeraldL Larson Ram R Chawla C S Subramaniam Thomas V John | | 0，，01： | 1 |
| 16 | Feasibility and Predictability of Perioperative PET and Estrogen Receptor Ligand in Patients with Invasive Breast Cancer显示文摘 | Mary L. Gemignani Sujata Patil Venkatraman E. Seshan Michelle Sampson John L. Humm Jason S. Lewis Edi Brogi Steven M. Larson Monica Morrow Neeta Pandit-Taskar | 2013 | Journal of Nuclear Medicine2013，，10： | 1 |
| 17 | Functional Outcomes After Ileal Pouch-Anal Anastomosis for Chronic Ulcerative Colitis显示文摘 | Ridzuan Farouk John H. Pemberton Bruce G. Wolff Roger R. Dozois Scott Browning Dirk Larson | 2000 | Annals of Surgery2000，，： | 1 |
| 18 | Review of 1027 Patients With Newly Diagnosed Multiple Myeloma显示文摘 | Robert A. Kyle Morie A. Gertz Thomas E. Witzig John A. Lust Martha Q. Lacy Angela Dispenzieri Rafael Fonseca S. Vincent Rajkumar Janice R. Offord Dirk R. Larson Matthew E. Plevak Terry M. Therneau Philip R. Greipp | 2003 | Mayo Clinic Proceedings2003，，1： | 1 |
| 19 | Advantages of fast-track recovery after laparoscopic right hemicolectomy for colon cancer显示文摘 | Vassiliki L. Tsikitis Stefan D. Holubar Eric J. Dozois Robert R. Cima John H. Pemberton David W. Larson | 2010 | Surgical Endoscopy2010，，8： | 1 |
| 20 | Pow- ers Absolute Calibration of a Geodetic Time Transfer Sys- tem 显示文摘 | John Plumb Kristine M Larson Joe White and Ed | 2005 | IEEE transactions on ultrasonics ferroelec- trics and frequency control2005，52，11： | 1 |
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