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| 1 | Current trends in staging rectal cancer显示文摘Management of rectal cancer has evolved over the years. In this condition preoperative investigations assist in deciding the optimal treatment. The relation of the tumor edge to the circumferential margin (CRM) is an important factor in deciding the need for neoadjuvant treatment and determines the prognosis. Those with threatened or involved margins are offered long course chemoradiation to enable R0 surgical resection. Endoanal ultrasound (EUS) is useful for tumor (T) staging; hence EUS is a useful imaging modality for early rectal cancer. Magnetic resonance imaging (MRI) is useful for assessing the mesorectum and the mesorectal fascia which has useful prognostic significance and for early identification of local recurrence. Computerized tomography (CT) of the chest, abdomen and pelvis is used to rule out distant metastasis. Identification of the malignant nodes using EUS, CT and MRI is based on the size, morphology and internal characteristics but has drawbacks. Most of the common imaging techniques are suboptimal for imaging following chemoradiation as they struggle to differentiate fibrotic changes and tumor. In this situation, EUS and MRI may provide complementary information to decide further treatment. Functional imaging using positron emission tomography (PET) is useful, particularly PET/CT fusion scans to identify areas of the functionally hot spots. In the current state, imaging has enabled the multidisciplinary team of surgeons, oncologists, radiologists and pathologists to decide on the patient centered management of rectal cancer. In future, functional imaging may play an active role in identifying patients with lymph node metastasis and those with residual and recurrent disease following neoadjuvant chemoradiotherapy. | Abdus Samee Chelliah Ramachandran Selvasekar | 2011 | World Journal of Gastroenterology2011，17，7： | 26 |
| 2 | From traditional serrated adenoma to tubulovillous adenoma and beyond显示文摘It is well established that colorectal cancer develops from a series of precursor epithelial polyps, including tubular adenomas, villous/tubulovillous adenomas(VA/TVA), sessile serrated adenomas(SSA) and traditional serrated adenomas(TSA). Of these, TSAs are least common and account for only 5% of all serrated polyps. TSAs are characterised by the presence of a 'pinecone-like' architecture, granular eosinophilic cytoplasm, luminal serrations, ectopic crypt foci(ECF) and elongated, pencillate nuclei. However, the distinct slit-like luminal serrations, reminiscent of small bowel mucosa, appear to be the most unique and reproducible feature to distinguish TSAs from other polyps. There is a contention that TSAs are not inherently dysplastic and that the majority do not show cytological atypia. Two types of dysplasia are associated with TSA. Serrated dysplasia is less well recognised and less commonly encountered than adenomatous dysplasia. In addition, it is now becoming increasingly evident that TSAs can be admixed with HP, SSA and VA/TVA. At a genetic level, polyps may switch phenotype as they accumulate genetic changes, evolving from a serrated pathway to a more conventional one, which could be the basis for a spectrum theory starting out with a TSA with serration and ECF evolving into a TSA with conventional dysplasia and, eventually, to a well-developed conventional adenoma. Nevertheless, there is an exigency for future studies to provide further illumination and bridge the gaps in our present understanding. | Sangeetha N Kalimuthu Adeline Chelliah Runjan Chetty | 2016 | World Journal of Gastrointestinal Oncology2016，8，12： | 2 |
| 3 | Performance Bounds of Algorithms for Scheduling Advertisements on a Web Page显示文摘 | Milind Dawande Subodha Kumar Chelliah Sriskandarajah | 2003 | Journal of Scheduling2003，，4： | 1 |
| 4 | Some applications of the generalized traveling salesman problem 显示文摘 | Laporte Gilbert Asef-Vaziri Ardavan Sriskandarajah Chelliah | 1996 | The Journal of the Operational Research Society1996，47，12： | 1 |
| 5 | Factors Affecting Insecticide Induced Resurgence of the Brown Planthopper, Nilaparvata lugens on Rice 显示文摘 | CHELLIAH S HE1NRICHS E A | 1980 | Environ Entomol1980，9，6： | 1 |
| 6 | Effect of Sub-lethal does of Three Insecticides on the Reproductive Rate of the Brown Planthopper, Nilaparvata lugens, on Rice显示文摘 | CHELLIAH S FABELLAR L T HEINRICHS E A | 1980 | Environmental Entomology1980，9，6： | 1 |
| 7 | Inhibition of cancer cell prolifer-ation and apoptosis-inducing activity of fungal taxol and its precur-sor baccatin III purified from endophytic Fusarium solani显示文摘 | Balabhadrapatruni VSK Chelliah | | 0，，13： | 1 |
| 8 | UV-B-induced signaling events lead- ing to enhanced-production of catharanthine in Catharan- thus roseus cell suspension cultures 显示文摘 | Ramani S Chelliah J | 2007 | BMC Plant Biolo- gy2007，7，61： | 1 |
| 9 | Factors affecting insecticide-induced resurgence of the brown planthopper,Nilapavata lugens on rice显示文摘 | CHELLIAH S HEINRICHS E A | 1980 | Environmental Entomology1980，9，6： | 1 |
| 10 | Effect of sub-lethaldoses of three insecticidesd on the reproductive rates of thebrown planthopper,Nilaparvata lugens,on rice显示文摘 | Chelliah S Fabellar L T Heinrichs E A | 1980 | Environ-mental Entomology1980，，9： | 1 |
| 11 | Inducible nitric oxide synthase mediates delaved myocardial protection induced by activation of adenosine A receptor:evidence from gene-knockout mice显示文摘 | Xi L Chelliah J | 2000 | Circulation2000，，8： | 1 |
| 12 | Factors affecting insecticide-in-duced esurgence of the brown planthopper,Nilparvata lugens,on rice显示文摘 | Chelliah S Heinrichs E A | 1980 | Environmental Entomology1980，，9： | 1 |
| 13 | Inducible nitric oxide synthase mediates delayed myocardial protection induced by activation of adenosine A1 receptors: evidence from gene-knockout mice显示文摘 | Zhao T Xi L Chelliah J | 2000 | Circulation2000，102，： | 1 |
| 14 | The NCEP/NCAR 40-yeax reanalysis project 显示文摘 | E Kalnay M Kanamitsu R Kistler WCollins D Deaven L Gandin M Iredell S Saha G White J Woollen Y Zhu M Chelliah W Ebisuzaki W Higgins J Janowiak KC Mo C Ropelewski J Wang A Leetmaa R Reynolds R Jenne D Joseph | 1996 | Bulletin of the American Meteorological Society (S0003-0007)1996，77，3： | 1 |
| 15 | Natural enemies of rice yellow stem borer,Scirpophaga incertulas (Walker)and its relationship with weather elements显示文摘 | Chandramohan N Chelliah S | 1990 | Journal of Biological Control1990，4，2： | 1 |
| 16 | Inducible nitric oxide synthase mediates delayed myocardial protection induced by activation of adenosine A(1) receptors:evidence from gene-knockout mice显示文摘 | Zhao T Xi L Chelliah J | 2000 | Circulation2000，102，： | 1 |
| 17 | Factors affecting insecticides - induced resurgence of the brown planthopper, Nilaparvata lugens on rice 显示文摘 | Chelliah S Heinrich EA | 1980 | Environ Entomol1980，9，6： | 1 |
| 18 | Effects of Sub-lethal Doses of Three Insecticides on the Reproductive Rate of the Brown Planthopper, Nilapavata lugens on Rice显示文摘 | CHELLIAH S FABELLAR L T HEINRICHS E A | 1980 | Environ Entomol1980，9，6： | 1 |
| 19 | Rare case of breast secondary to rectal adenocarcinoma显示文摘 | Sanchez L D Chelliah T Meisher I | 2008 | South Med J2008，101，10： | 1 |
| 20 | Resurgence of Nilaparvata lugens (Stal) populations as influenced by mothod and timing of insecticide applications in lowland rice 显示文摘 | Heinrich EA Aquino GB Chelliah S | 1982 | Environ Entomol1982，11，1： | 1 |
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