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| 1 | Panitumumab and irinotecan versus irinotecan alone for patients with KRAS wild-type, fluorouracil-resistant advanced colorectal cancer (PICCOLO): a prospectively stratified randomised trial显示文摘 | Matthew T Seymour Sarah R Brown Gary Middleton Timothy Maughan Susan Richman Stephen Gwyther Catherine Lowe Jennifer F Seligmann Jonathan Wadsley Nick Maisey Ian Chau Mark Hill Lesley Dawson Stephen Falk Ann O’Callaghan Kim Benstead Philip Chambers Alfred | 2013 | Lancet Oncology2013，，8： | 6 |
| 2 | Nat Genet:单基因突变导致过敏性皮炎的发生显示文摘最近,研究者们鉴定出了一类导致神经性皮炎发生的关键基因突变:CARDll。来自美国NIH过敏与传染病研究所的研究者们通过对四个没有血缘关系的患病家庭进行分析,发现了这一导致疾病产生的基因、 | Chi A Ma, Yuan Zhang, Michael A Weinreich, Jonathan J Lyons, Celeste G Nelson, Thomas DiMaggio, Kelly D Stone, Joshua D Milner Jeffrey R Stinson, Elisa Ruffo, Batsukh Dorjbal, Swadhinya Arjunaraja, Kelsey Voss, Andrew L Snow Jordan K Abbott, Pia J Hauk, Paul R Reynolds, Erwin W Gelfand Elisa Ruffo Salomé Glauzy, Natsuko Yamakawa, Eric Meffre Jennifer Stoddard, Julie Niemela, Sergio D Rosenzweig Yu Zhang, Helen F Matthews Joshua J McElwee Nina Jones Alejandro Palma, Matías Oleastro, Emma Prieto, Andrea R Bernasconi, Geronimo Dubra, Silvia Danielian, Jonathan Zaiat, Marcelo A Marti Brian Kim Megan A Cooper Neil Romberg | 2017 | 现代生物医学进展2017，17，27： | 3 |
| 3 | 一种房颤风险评分系统的建立(Framingham心脏研究):基于社区的队列研究显示文摘背景房颤导致了发病率和病死率的显著上升。本研究旨在建立一种预测个体罹患房颤绝对风险的风险评分系统,并提供研究人员评价新危险因素的流程。方法作者评估了Framingham心脏研究中于1968年6月至1987年9月间进行了8044次检测的4764例参与者(55%为女性,年龄45~95岁)。此后,参与者被随访至房颤首发,随访期最长达10年。多变量Coxi回归确认出1(1年内罹患房颤的临床危险因素。次级分析纳入了常规超声心动图检测指标(5152例4参与者,7156次检测)对房颤风险进行再分层评估,并评价超声检测指标能否提高风险预测能力。结果4764例参与者中的457例4(10%)罹患房颤。年龄、性别、体重指数、收缩压、降压治疗、PR间期、有临床意义的心脏杂音及心力衰竭与房颤相关,并被纳入了风险评分模型(除体重指数P=0.08外,其余均为P〈0.05),模型的C统计量为0.78(95%CI0.76~0.80)。10年房颤风险随年龄变化:年龄〈65岁的人群中53例(1%)风险高于15%,而〉65岁的人群中为783例(27%)。为提高预测能力而纳入超声检测指标仅使模型C统计量略微增高,由0.78(95%C10.75~0.80)增至0.79(95%CI0.77~0.82:P=0.005)。超声心动图检测指标并不能改善风险再分层评估(P=0.18)。结论基于社区医疗中易得的临床因素建立的风险评分系统,有助于确认社区个体罹患房颤的风险,评估技术或标志物能否改善风险预测,以及针对高危个体采取预防措施。 | Renate B Schnabel Lisa M Sullivan Daniel Levy Michael J Pencina Joseph M Massaro Ralph B D'Agostino Sr Christopher Newton-Cheh Jennifer F Yamamoto Jared W Magnani Thomas M Tadros William B Kannel Thomas J Wang Patrick T Ellinor Philip A Wolf Ramachanclran S Vasan Emelia J Benjamin 黄刚(译) | 2009 | 世界临床医学2009，，9： | 2 |
| 4 | The role of laparoscopic nephrectomy in pediatric xanthogranulomatous pyelonephritis: a case report显示文摘 | F Brown Chamberlain Jennifer C | 2013 | Case reports in urology2013，2013，59： | 1 |
| 5 | Interleukin - 6 secretion in vitro is up - regulated in ectopic and eutopic endometrial stromal cells from women with endometriosis 显示文摘 | JENNIFER F TSENG ISABELLE P | 1996 | Fertil Steril1996，81，3： | 1 |
| 6 | Innovation and industry evolution 显示文摘 | Reinganum Jennifer F | 1985 | The Quarterly Journal of Economics1985，2，： | 1 |
| 7 | Use of supplementary cementing materials to increase the resistance to chloride ion penetration of concrete cured at elevated temperatures显示文摘 | RACHEL J D CHRIS A F JENNIFER N | 1994 | ACI Materials Journal1994，91，1： | 1 |
| 8 | Capacitors显示文摘 | Sarjeant W J Zirnheld Jennifer MacDougall F W | 1998 | IEEE Trans on Plasma Science1998，26，5： | 1 |
| 9 | Bacterial vaginosis : a problematic infection from both a perinatal and neonatal perspective显示文摘 | Jeff M Denney Jennifer F Culhane | 2009 | Seminars in Fetal and Neonatal Medicine2009，14，4： | 1 |
| 10 | Global burden of human food-borne trematodiasis: a systematic review and meta-analysis显示文摘 | Thomas Fürst Jennifer Keiser Jürg Utzinger | 2012 | The Lancet Infectious Diseases2012，，3： | 1 |
| 11 | Quantitative determination of fluorinated alkyl substances by large-volume-injection liquid chromatography tandem mass spectrometry-characterization of municipal wastewaters显示文摘 | SCHULTZ Melissa M BAROFSKY Douglas F FIELD Jennifer A | 2006 | Environmental Science & Technology2006，40，1： | 1 |
| 12 | Microbial community variation and it's relationship with nitrogen mineralization in historically altered forests显示文摘 | Jennifer M F Teri C B Monica G T | 2006 | Ecology2006，87，3： | 1 |
| 13 | Bacteriocins: safe, natural antimicrobials for food preservation 显示文摘 | Jennifer Cleveland Thomas J Montville Ingolf F Nes | 2001 | International Journal of Food Microbiology2001，71，： | 1 |
| 14 | Biomarkers of immune dysfunction following combination antiretroviral therapy for HIV infection显示文摘 | Gregor F Lichtfuss Jennifer Hoy Reena Rajasuriar Marit Kramski Suzanne M Crowe Sharon R Lewin | 2011 | Biomarkers Med2011，，： | 1 |
| 15 | Bacterocins:safe,natural antimicrobials for food preservation显示文摘 | Jennifer C Thomas J M Ingolf F N | 2001 | International Journal of Food Microbiology2001，71，： | 1 |
| 16 | A case study of the changes in the speech-evoked auditory brainstem response associated with auditory training in children with auditory processing disorders显示文摘 | SRIDHAR K JENNIFER F CASEY R | 2013 | Int J Pediatric Otorhinolaryngol2013，77，： | 1 |
| 17 | Evaluating form and function of regional partnerships:applying social net work analysis to the network for a healthy california,2001-2007显示文摘 | Jennifer G Marcy S Heather K F | | 0，，04： | 1 |
| 18 | Differences by race and gender in expected starting salaries of bachelor degree recipients in connecticut 显示文摘 | RHONA C F JENNIFER L B MARYANNE T C | 2007 | The Negro Educational Review2007，58，4： | 1 |
| 19 | IMP3 expression is correlated with histologic grade of tung adenocarcinoma 显示文摘 | Jennifer J Hosey F Yang Q | 2010 | Human Pathol2010，41，4： | 1 |
| 20 | Aquatic herbicides and herbicide contami -nants: In vitro cytotoxicity and cell-cycle analysis显示文摘 | Jennifer L F Rayburn A L | 2006 | EnvironmentalToxicology2006，21，3： | 1 |
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