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| 1 | Endoscopic retrograde cholangiopancreatography during pregnancy without radiation显示文摘AIM: To present our experience with pregnant patients who underwent endoscopic retrograde cholangiopancreatography (ERCP) without using radiation, and to evaluate the acceptability of this alternative therapeutic pathway for ERCP during pregnancy. METHODS: Between 2000 and 2008, six pregnant women underwent seven ERCP procedures. ERCP was performed under mild sedoanalgesia induced with pethidine HCl and midazolam. The bile duct was cannulated with a guidewire through the papilla. A catheter was slid over the guidewire and bile aspiration and/or visualization of the bile oozing around the guidewire was used to confirm correct cannulation. Following sphincterotomy, the bile duct was cleared by balloon sweeping. When indicated, stents were placed. Confirmation of successful biliary cannulation and stone extraction was made by laboratory, radiological and clinical improvement. Neither fluoroscopy nor spot radiography was used during the procedure. RESULTS: The mean age of the patients was 28 years (range, 21-33 years). The mean gestational age for the fetus was 23 wk (range, 14-34 wk). Five patients underwent ERCP because of choledocholithiasis and/orcholedocholithiasis-induced acute cholangitis. In one case, a stone was extracted after precut papillotomy with a needle-knife, since the stone was impacted. One patient had ERCP because of persistent biliary fistula after hepatic hydatid disease surgery. Following sphincterotomy, scoleces were removed from the common bile duct. Two weeks later, because of the absence of fistula closure, repeat ERCP was performed and a stent was placed. The fistula was closed after stent placement. Neither post-ERCP complications nor premature birth or abortion was seen. CONCLUSION: Non-radiation ERCP in experienced hands can be performed during pregnancy. Stent placement should be considered in cases for which complete common bile duct clearance is dubious because of a lack of visualization of the biliary tree. | Adem Akcakaya Orhan Veli Ozkan Ismail Okan Orhan Kocaman Mustafa Sahin | 2009 | World Journal of Gastroenterology2009，15，29： | 17 |
| 2 | Same-day colonoscopy preparation with Senna alkaloids and bisacodyl tablets:A pilot study显示文摘AIM:To evaluate the efficacy of same-day bowel preparation with Senna alkaloids combined with bisacodyl tablets in routine colonoscopy procedures.METHODS:Between March and June 2013,a sameday bowel preparation was implemented in our endoscopy unit.The preparation consisted of a semi-liquid,fiber-free diet one day prior to the procedure,with two bisacodyl tablets after lunch and dinner,and 250 mL of Senna alkaloid with 1.5 L of drinking water at 6 am the day of the procedure.The quality control parameters of colonoscopy were evaluated and implemented according to the guidelines of the American Society for Gastrointestinal Endoscopy.The pre-procedure,duringprocedure and post-procedure patient data were collected and analyzed:(1) pre-procedure(age,gender,comorbid diseases,colonoscopy indications,complete lack of compliance with the bowel preparation protocol);(2) during-procedure(sedation dose,duration of colonoscopy,withdrawal time,cecal intubation rate,polyp detection rate,Boston Bowel Preparation Scores and presence of foam and clear liquid); and(3) postprocedure(visual analogue scale score,pain during the procedure,patient satisfaction and premature withdrawal due to the insufficient bowel preparation).RESULTS:A total of 75 patients were included in this study with a mean age of 54.64 ± 13.29 years; 53.3%(40/75) were female and 46.7%(35/75) were male.A complete lack of compliance with the bowel preparation protocol was seen in 6.7% of patients(5/75).The mean total duration of colonoscopy was 16.12 ± 6.51 min,and the mean withdrawal time was 8.89 ± 4.07 min.The cecal intubation rate was 93.8%(61/64) and the polyp detection rate was 40%(30/75).The mean Boston Bowel Preparation Score was 7.38 ± 1.81,with the following distribution:right colon,2.34 ± 0.89; transverse colon,2.52 ± 0.67; left colon,2.52 ± 0.63.The mean visual analogue scale score was 4.59 ± 1.57.Due to insufficient bowel preparation,seven patients(7/75; 9.3%) were asked to repeat the procedure.Of these,five patients had poor or modest compliance with the protocol,and two patients reported constipation.Premature withdrawal due to insufficient bowel preparation was 2.7%(2/75).The overall satisfaction with the protocol was 86.7%(65/75),with patients reporting they would prefer the same protocol in a repeat procedure.CONCLUSION:The same-day administration of Senna alkaloids appears to be a safe and effective bowel cleansing protocol for colonoscopy procedures. | Erdinc Yenidogan Ismail Okan Huseyin Ayhan Kayaoglu Gokhan Giray Akgul Mufit Sansal Servet Tali Zeki Ozsoy Mustafa Sahin | 2014 | World Journal of Gastroenterology2014，20，41： | 7 |
| 3 | Mechanical lithotripsy and/or stenting in management of difficult common bile duct stones显示文摘BACKGROUND:Mechanical lithotripsy and/or stent insertion is the alternative therapeutic approach in difficult endoscopic retrograde cholangiopancreatography (ERCP)case.This study was designed to investigate the appropriate treatment for extraction of bile duct stones in difficult cases of ERCP. METHODS:Between 2000 and 2008,744 ERCP procedures were performed in 592 patients with choledocholithiasis in our endoscopy unit.The demographic features,and clinical and laboratory findings were collected from a prospectively held database.Bile duct calculi were extracted by basket and/or balloon catheter following ERCP and sphincterotomy.Patients with retained stones were regarded as difficult cases.These patients were treated with mechanical lithotripsy and those with incomplete clearance of stones underwent stent placement. RESULTS:Two hundred and forty-five patients(41%) were male and 347(59%)were female with a mean age of 58 years(range 19-95 years).Stones were impacted in 27 patients(5%).Stone extraction was performed by basket and/or balloon catheter in 610 ERCP procedures,and lithotripsy was performed in 70 ERCP procedures.Forty- four patients underwent stent insertion,and 20 underwent stent replacement.Morbidity occurred in 39 patients (5%),with no mortality associated with the procedure.Hemorrhage occurred in 9 patients and basket impaction in 4.Mild pancreatitis and cholangitis developed in 12 and 11 patients,respectively. CONCLUSION:Difficult cases of bile duct stones can be treated successfully with lithotripsy,and a stent should be applied when the common bile duct cannot be cleared completely. | Adem Akcakaya Orhan Veli Ozkan Gurhan Bas Atilla Karakelleoglu Orhan Kocaman Ismail Okan Mustafa Sahin | 2009 | Hepatobiliary & Pancreatic Diseases International2009，8，5： | 5 |
| 4 | Low incidence of colorectal dysplasia and cancer among patients with ulcerative colitis: A Turkish referral centre study显示文摘 | Murat Kekilli Ulku Dagli Ismail Hakki Kalkan Bilge Tunc Selcuk Disibeyaz Aysel Ulker Burhan Sahin | 2010 | Scandinavian Journal of Gastroenterology2010，，4： | 1 |
| 5 | Low incidence of colorectal dysplasia and cancer among patients with ulcerative colitis: A Turkish referral centre study显示文摘 | Murat Kekilli Ulku Dagli Ismail Hakki Kalkan Bilge Tunc Selcuk Disibeyaz Aysel Ulker Burhan Sahin | 2010 | Scandinavian Journal of Gastroenterology2010，，4： | 1 |
| 6 | The Lack of Benefit of a Combination of an Angiotensin Receptor Blocker and Calcium Channel Blocker on Contrast-Induced Nephropathy in Patients with Chronic Kidney Disease显示文摘 | Nilufer Oguzhan Havva Cilan Murat Sipahioglu Aydin Unal Ismail Kocyigit Feridun Kavuncuoglu Tamer Arikan Mahmut Akpek Deniz Elcik Omer Sahin Ebru Gulme Cigdem Pala Bulent Tokgoz Cengiz Utas Abdurrahman Oguzhan Oktay Oymak | 2013 | Renal Failure2013，，4： | 1 |
| 7 | Loneliness, self-esteem, and life satisfaction as predictors of Internet addiction显示文摘 | Bahadir Bozoglan Veysel Demirer Ismail Sahin | 2013 | Scandinavian Journal of Psychology2013，54，4： | 1 |
| 8 | Using Rogers'Theory to Interpret Instructional Computer Use by COE Faculty显示文摘 | Ismail Sahin Ann Thompson | 2006 | Journal of Research on Technology in Education2006，，10： | 1 |
| 9 | Railway operations, time-tabling and control 显示文摘 | Marin Marinov Ismail Sahin Stefano Ricci Gordana Vasic-Franklin | 2013 | Research in Transportation Economics2013，，41： | 1 |
| 10 | Predicting Student Satisfaction in Distance Educaiton and Learning Environments 显示文摘 | Ismail SAHIN | 2007 | Turkish Online Journal of Distance Education2007，8，2： | 1 |
| 11 | Thalidomide decreases the plasma levels of IL-1 and TNF following burn injury: Is it a new drug for modulation of systemic inflammatory response显示文摘 | Muhitdin Eski Ismail Sahin Mustafa Sengezer Muhittin Serdar Ahmet Ifran | 2007 | Burns2007，，1： | 1 |
| 12 | Disinfection by-products precursors removal by enhanced coagulation and PAC adsorption 显示文摘 | Vedat Uyak Sema Yavuz Ismail Toroz Sahin Ozaydin Esra Ates Genceli | 2007 | Desalination2007，216，： | 1 |
| 13 | Analysis of community college students’ educational Internet use and metacognitive learning strategies显示文摘 | Ahmet Oguz Akturk Ismail Sahin | 2010 | Procedia - Social and Behavioral Sciences2010，，2： | 1 |
| 14 | Opportunity Detection for OFDMA-Based Cognitive RadioSystems with Timing Misalignment 显示文摘 | SAHIN Mustafa E GUVENG Ismail ARSLAN Huseyin | 2009 | IEEE Trans onWireless Communications2009，8，10： | 1 |
| 15 | Predicting student satisfaction in distance education and learning environment显示文摘 | Ismail SAHIN | 2008 | Turkish Online Journal of Distance Ed- ucation2008，，2： | 1 |
| 16 | Accuracy of endoscopic ultrasound‐guided fine needle aspiration cytology on the differentiation of malignant and benign pancreatic cystic lesions: A single‐center experience显示文摘 | Dilek Oguz Erkin ?zta? Ismail Hakk? Kalkan Oyku Tayfur Bahattin Cicek Gulden Aydog Mevlut Kurt Yavuz Beyazit Digdem Etik Isilay Nadir Burhan Sahin | 2013 | Journal of Digestive Diseases2013，，3： | 1 |
| 17 | The in-vivo assessment of Turkish propolis and its nano form on testicular damage induced by cisplatin显示文摘Objective: Chemotherapeutic drugs, such as cisplatin(CP), which are associated with oxidative stress and apoptosis, may adversely affect the reproductive system. This study tests whether administration of propolis and nano-propolis(NP) can alleviate oxidative stress and apoptosis in rats with testicular damage induced by CP.Methods: In this study, polymeric nanoparticles including propolis were synthesized with a green sonication method and characterized using Fourier transform-infrared spectroscopy, Brunauer-EmmettTeller, and wet scanning transmission electron microscopy techniques. In total, 56 rats were divided into the following seven groups: control, CP, propolis, NP-10, CP + propolis, CP + NP-10, and CP + NP-30.Propolis(100 mg/kg), NP-10(10 mg/kg), and NP-30(30 mg/kg) treatments were administered by gavage daily for 21 d, and CP(3 mg/kg) was administered intraperitoneally in a single dose. After the experiment,oxidative stress parameters, namely, malondialdehyde(MDA), glutathione(GSH), glutathione peroxidase(GPx), and catalase(CAT), and apoptotic pathways including B cell leukemia/lymphoma-2 protein(Bcl-2)and Bcl-2-associated X protein(Bax) were measured in testicular tissues. Furthermore, sperm quality and weights of the testis, epididymis, right cauda epididymis, seminal vesicles and prostate were evaluated.Results: Propolis and NP(especially NP-30) were able to preserve oxidative balance(decreased MDA levels and increased GSH, CAT, and GPx activities) and activate apoptotic pathways(decreased Bax and increased Bcl-2) in the testes of CP-treated rats. Sperm motility in the control, CP, and CP + NP-30 groups were 60%, 48.75%, and 78%, respectively(P<0.001). Especially, NP-30 application completely corrected the deterioration in sperm features induced by CP.Conclusion: The results show that propolis and NP treatments mitigated the side effects of CP on spermatogenic activity, antioxidant situation, and apoptosis in rats. | Pinar Tatli Seven Ismail Seven Selcan Karakus Seda Iflazoglu Mutlu Seyma Ozer Kaya Gozde Arkali Merve Ilgar Ezgi Tan Yesim Muge Sahin Deniz Ismik Ayben Kilislioglu | 2021 | Journal of Integrative Medicine2021，19，5： | 0 |
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